Development Level

Tbio 39 | 10,625
Tdark 4 | 7,003
Tchem 2 | 1,890
Tclin 1 | 602

Collection

Eligible non-olfactory GPCR Proteins 1 | 143

IMPC Term

decreased bone mineral density 3 | 126
abnormal behavior 2 | 226
abnormal retina morphology 2 | 100
abnormal sleep behavior 2 | 63
decreased body length 2 | 108
decreased bone mineral content 2 | 157
decreased lean body mass 2 | 195
decreased prepulse inhibition 2 | 52
increased circulating chloride... 2 | 43
increased or absent threshold ... 2 | 128
preweaning lethality, complete... 2 | 633
preweaning lethality, incomple... 2 | 260
abnormal behavioral response t... 1 | 52
abnormal bone mineralization 1 | 55
abnormal bone structure 1 | 131
abnormal digit morphology 1 | 13
abnormal lens morphology 1 | 73
abnormal retinal blood vessel ... 1 | 18
absent startle reflex 1 | 15
convulsive seizures 1 | 11
decreased body weight 1 | 174
decreased circulating amylase ... 1 | 24
decreased circulating insulin ... 1 | 75
decreased circulating serum al... 1 | 79
decreased circulating total pr... 1 | 41
decreased erythrocyte cell num... 1 | 43
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular vol... 1 | 50
decreased rib number 1 | 59
decreased startle reflex 1 | 48
female infertility 1 | 34
hyperactivity 1 | 108
hypoactivity 1 | 89
improved glucose tolerance 1 | 56
increased blood urea nitrogen ... 1 | 44
increased bone mineral content 1 | 92
increased circulating alkaline... 1 | 119
increased circulating total pr... 1 | 20
increased circulating triglyce... 1 | 24
increased fasted circulating g... 1 | 68
increased mean corpuscular hem... 1 | 25
increased startle reflex 1 | 38
increased vertical activity 1 | 18

Disease

medulloblastoma, large-cell 31 | 6,234
glioblastoma 27 | 5,572
osteosarcoma 24 | 7,933
ovarian cancer 22 | 8,484
atypical teratoid / rhabdoid tumor 21 | 4,369
oligodendroglioma 21 | 2,849
primitive neuroectodermal tumor 20 | 3,031
psoriasis 20 | 6,685
Breast cancer 18 | 3,094
Carcinoma 18 | 2,147
astrocytic glioma 18 | 2,241
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,289
pilocytic astrocytoma 18 | 3,086
lung carcinoma 17 | 2,844
Amyotrophic Lateral Sclerosis 16 | 431
ependymoma 16 | 2,514
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,956
invasive ductal carcinoma 16 | 2,950
lung cancer 15 | 4,466
pediatric high grade glioma 15 | 2,712
lung adenocarcinoma 14 | 2,713
non-small cell lung cancer 14 | 2,798
intraductal papillary-mucinous carcinoma (IPMC) 13 | 2,988
cystic fibrosis 11 | 1,665
ductal carcinoma in situ 11 | 1,745
malignant mesothelioma 11 | 3,162
pituitary cancer 11 | 1,972
posterior fossa group A ependymoma 11 | 1,511
adult high grade glioma 10 | 2,148
pancreatic cancer 10 | 2,300
subependymal giant cell astrocytoma 10 | 2,287
Cancer 9 | 2,346
Pick disease 9 | 1,893
group 4 medulloblastoma 9 | 1,875
acute quadriplegic myopathy 8 | 1,157
medulloblastoma 8 | 1,524
Atopic dermatitis 7 | 944
colon cancer 7 | 1,475
interstitial cystitis 7 | 2,299
sonic hedgehog group medulloblastoma 7 | 1,482
ulcerative colitis 7 | 2,087
Schizophrenia 6 | 501
active Crohn's disease 6 | 918
adrenocortical carcinoma 6 | 1,427
atypical teratoid/rhabdoid tumor 6 | 1,095
breast carcinoma 6 | 1,614
cutaneous lupus erythematosus 6 | 1,056
gastric carcinoma 6 | 832
group 3 medulloblastoma 6 | 2,254
spina bifida 5 | 1,064
Autistic Disorder 4 | 320
Cardiovascular system disease 4 | 194
Endometriosis 4 | 535
Intellectual disability 4 | 573
Melanoma 4 | 261
active ulcerative colitis 4 | 477
aldosterone-producing adenoma 4 | 664
astrocytoma 4 | 1,493
fibroadenoma 4 | 557
Acquired metabolic disease 3 | 267
Duchenne muscular dystrophy 3 | 602
Neuropathy 3 | 210
Rheumatoid Arthritis 3 | 1,160
acute myeloid leukemia 3 | 780
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 499
diabetes mellitus 3 | 1,663
juvenile dermatomyositis 3 | 1,189
nasopharyngeal carcinoma 3 | 1,056
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,795
posterior fossa group B ependymoma 3 | 1,530
sarcoidosis 3 | 358
tuberculosis 3 | 1,557
Asthma 2 | 349
Bipolar Disorder 2 | 266
Cerebrovascular disease 2 | 231
Chronic obstructive pulmonary disease 2 | 146
Colorectal Neoplasms 2 | 217
Craniofacial Abnormalities 2 | 147
Down syndrome 2 | 548
Heart conduction disease 2 | 65
Hyperopia 2 | 33
Hypertension 2 | 287
Hypertensive disease 2 | 193
Inflammation 2 | 109
Malaria 2 | 140
Motor neuron disease 2 | 39
Myopia 2 | 99
Neurodegenerative disease 2 | 383
Prostate cancer 2 | 172
Prostatic Neoplasms 2 | 471
Vascular disease 2 | 281
chronic rhinosinusitis 2 | 512
cystic fibrosis and chronic rhinosinusitis 2 | 213
dermatomyositis 2 | 933
gastric cancer 2 | 430
hereditary spastic paraplegia 2 | 313
interstitial lung disease 2 | 291
primary Sjogren syndrome 2 | 789
primary pancreatic ductal adenocarcinoma 2 | 1,271
tuberculosis and treatment for 3 months 2 | 327

Tissue

Blood and immune system 45 | 17,995
Cardiovascular System 45 | 17,958
Digestive Tract 45 | 18,473
Endocrine System 45 | 18,512
Female tissues 45 | 18,647
Liver and Pancreas 45 | 18,136
Male tissues 45 | 17,969
Nervous System 45 | 18,561
Urinary Tract 45 | 18,444
Respiratory system 44 | 17,484
Skin and soft tissues 44 | 18,115

Target Family

Non-IDG 28 | 11,971
Enzyme 8 | 4,146
Transporter 4 | 473
Ion Channel 2 | 341
Transcription Factor 2 | 1,400
GPCR 1 | 406
Kinase 1 | 634

GWAS Trait

Amyotrophic lateral sclerosis ... 46 | 46
Obesity-related traits 380 | 380
Schizophrenia 334 | 334
Height 250 | 250
Post bronchodilator FEV1/FVC r... 192 | 192
Body mass index 180 | 180
IgG glycosylation 162 | 162
Inflammatory bowel disease 117 | 117
Post bronchodilator FEV1 112 | 112
Crohn's disease 110 | 110
Blood metabolite levels 103 | 103
Type 2 diabetes 94 | 94
3-hydroxy-1-methylpropylmercap... 93 | 93
3-hydroxypropylmercapturic aci... 92 | 92
Ulcerative colitis 89 | 89
Platelet count 79 | 79
Systemic lupus erythematosus 78 | 78
HDL cholesterol 76 | 76
Rheumatoid arthritis 74 | 74
Cholesterol, total 73 | 73
Menarche (age at onset) 73 | 73
Diisocyanate-induced asthma 72 | 72
Multiple sclerosis 68 | 68
LDL cholesterol 67 | 67
QT interval 58 | 58
Metabolite levels 55 | 55
Atopic dermatitis 54 | 54
Bipolar disorder and schizophr... 54 | 54
Breast cancer 54 | 54
Prostate cancer 54 | 54
Triglycerides 53 | 53
Bipolar disorder 52 | 52
HIV-1 control 50 | 50
Post bronchodilator FEV1/FVC r... 50 | 50
HIV-1 viral setpoint 49 | 49
Cognitive performance 48 | 48
Bone mineral density 46 | 46
Clozapine-induced agranulocyto... 46 | 46
Attention deficit hyperactivit... 44 | 44
Blood pressure 44 | 44
Coronary heart disease 43 | 43
Glomerular filtration rate (cr... 43 | 43
Parkinson's disease 43 | 43
Type 1 diabetes 42 | 42
PR interval in Tripanosoma cru... 40 | 40
Post bronchodilator FEV1 in CO... 39 | 39
Alzheimer's disease (cognitive... 38 | 38
Educational attainment 38 | 38
Pulmonary function 38 | 38
Diffuse large B cell lymphoma 37 | 37
Inflammatory skin disease 37 | 37
Beta-2 microglubulin plasma le... 36 | 36
Glucose homeostasis traits 36 | 36
Urate levels 36 | 36
Blood metabolite ratios 35 | 35
Psoriasis 35 | 35
Autism spectrum disorder, atte... 34 | 34
Migraine 33 | 33
Coronary artery disease 32 | 32
Metabolic traits 32 | 32
Waist-to-hip ratio adjusted fo... 32 | 32
Cognitive function 31 | 31
Colorectal cancer 31 | 31
Amyotrophic lateral sclerosis 30 | 30
Myopia (pathological) 30 | 30
Obesity 30 | 30
Response to amphetamines 30 | 30
Systolic blood pressure 30 | 30
Alzheimer's disease (late onse... 29 | 29
Celiac disease 29 | 29
Phospholipid levels (plasma) 29 | 29
Red blood cell traits 29 | 29
Advanced age-related macular d... 28 | 28
Dental caries 28 | 28
Fibrinogen levels 28 | 28
Parental extreme longevity (95... 28 | 28
Pulmonary function (interactio... 28 | 28
Asthma 27 | 27
Cognitive decline rate in late... 27 | 27
Glomerular filtration rate in ... 27 | 27
Longevity 27 | 27
Mean platelet volume 27 | 27
Chronic kidney disease 26 | 26
Diabetic kidney disease 26 | 26
Diastolic blood pressure 26 | 26
Coronary artery calcification 25 | 25
Metabolic syndrome 25 | 25
Pancreatic cancer 25 | 25
Protein quantitative trait loc... 25 | 25
Hypertension 24 | 24
Migraine - clinic-based 24 | 24
Parental longevity (combined p... 24 | 24
Primary biliary cirrhosis 24 | 24
Thiazide-induced adverse metab... 24 | 24
Menopause (age at onset) 23 | 23
Response to antipsychotic trea... 23 | 23
Age-related macular degenerati... 22 | 22
Immune response to smallpox va... 22 | 22
Mild influenza (H1N1) infectio... 22 | 22
Sudden cardiac arrest 22 | 22

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Laminin subunit alpha-2 LAMA2 Tbio Non-IDG -2.48634 321.9 131
Transmembrane protein 132B TMEM132B Tdark Non-IDG 0.00000 1.00 25
Thromboxane-A synthase TBXAS1 Tchem Enzyme -3.06668 1228.9 241
Plasma membrane calcium-transporting ATPase 2 ATP2B2 Tbio Transporter -2.03165 116.3 74
Protein N-lysine methyltransferase METTL21A METTL21A Tchem Enzyme 0.00000 1.05 62
Integrin alpha-9 ITGA9 Tbio Non-IDG -1.42298 25.6 96
Protein unc-13 homolog A UNC13A Tbio Non-IDG -1.78472 61.9 22
Ankyrin-3 ANK3 Tbio Non-IDG -2.16309 146.7 148
Catenin delta-2 CTNND2 Tbio Non-IDG -1.87512 92.2 112
Clavesin-1 CLVS1 Tbio Non-IDG -0.27300 2.43 56