Development Level

Tbio 51 | 11,445
Tdark 13 | 6,588
Tchem 4 | 1,598
Tclin 2 | 613

Collection

RFA-RM-18-021 2 | 328
GPCR: IDG Consortium (Targets) 1 | 126
Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

abnormal behavior 3 | 298
decreased lymphocyte cell numb... 3 | 83
decreased prepulse inhibition 3 | 82
preweaning lethality, complete... 3 | 979
preweaning lethality, incomple... 3 | 499
abnormal bone structure 2 | 187
decreased bone mineral density 2 | 126
increased circulating alkaline... 2 | 122
increased circulating chloride... 2 | 41
abnormal behavioral response t... 1 | 66
abnormal embryo size 1 | 220
abnormal heart morphology 1 | 162
abnormal joint morphology 1 | 23
abnormal placement of pupils 1 | 6
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
absent startle reflex 1 | 24
brachydactyly 1 | 19
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
convulsive seizures 1 | 13
decreased body length 1 | 101
decreased body weight 1 | 161
decreased circulating alanine ... 1 | 47
decreased circulating amylase ... 1 | 28
decreased circulating insulin ... 1 | 76
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased startle reflex 1 | 75
decreased threshold for audito... 1 | 26
enlarged heart 1 | 210
female infertility 1 | 60
hydrometra 1 | 53
hyperactivity 1 | 148
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating total pr... 1 | 28
increased circulating triglyce... 1 | 42
increased fasted circulating g... 1 | 76
increased heart rate variabili... 1 | 7
increased mean corpuscular hem... 1 | 36
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
increased vertical activity 1 | 24
small superior vagus ganglion 1 | 74
syndactyly 1 | 23

Disease

Carcinoma 50 | 11,493
medulloblastoma, large-cell 43 | 6,241
ependymoma 37 | 4,679
glioblastoma 34 | 5,792
atypical teratoid / rhabdoid tumor 32 | 5,112
osteosarcoma 32 | 7,950
ovarian cancer 31 | 8,520
adult high grade glioma 27 | 3,801
group 3 medulloblastoma 26 | 4,104
psoriasis 26 | 6,694
oligodendroglioma 25 | 2,850
Astrocytoma, Pilocytic 23 | 3,081
Breast cancer 23 | 3,578
primitive neuroectodermal tumor 23 | 3,035
Kidney cancer 22 | 2,613
astrocytic glioma 22 | 2,597
lung carcinoma 22 | 2,843
intraductal papillary-mucinous neoplasm (IPMN) 21 | 3,291
invasive ductal carcinoma 19 | 2,951
non-small cell lung cancer 19 | 2,890
intraductal papillary-mucinous adenoma (IPMA) 18 | 2,955
lung cancer 18 | 4,740
lung adenocarcinoma 16 | 2,716
pancreatic cancer 15 | 2,398
subependymal giant cell astrocytoma 15 | 2,287
Pick disease 14 | 1,894
Schizophrenia 14 | 1,160
ductal carcinoma in situ 14 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 14 | 2,989
malignant mesothelioma 14 | 3,232
pituitary cancer 14 | 1,972
Cancer 13 | 2,499
cystic fibrosis 13 | 1,696
acute quadriplegic myopathy 10 | 1,158
breast carcinoma 9 | 1,638
colon cancer 9 | 1,478
group 4 medulloblastoma 9 | 1,855
interstitial cystitis 9 | 2,312
Autosomal recessive predisposition 8 | 1,442
Liver cancer 8 | 604
Melanoma 8 | 711
Rheumatoid arthritis 8 | 1,191
active ulcerative colitis 8 | 764
adrenocortical carcinoma 8 | 1,428
gastric carcinoma 8 | 807
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
spina bifida 8 | 1,074
Atopic dermatitis 7 | 952
Bipolar Disorder 7 | 666
active Crohn's disease 7 | 922
cutaneous lupus erythematosus 7 | 1,057
ulcerative colitis 7 | 1,819
Amyotrophic lateral sclerosis 6 | 451
Intellectual disability 6 | 1,016
Skin cancer 6 | 469
aldosterone-producing adenoma 6 | 665
pediatric high grade glioma 6 | 1,064
Autistic Disorder 5 | 364
Cardiovascular system disease 5 | 246
Down syndrome 5 | 499
Dull intelligence 5 | 645
Endometriosis 5 | 540
Low intelligence 5 | 645
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Poor school performance 5 | 645
tuberculosis 5 | 2,010
Acquired metabolic disease 4 | 336
Anorexia nervosa 4 | 80
Arthritis, Rheumatoid 4 | 174
Cleft Palate 4 | 271
Essential Hypertension 4 | 94
Muscle Spasticity 4 | 195
Muscle hypotonia 4 | 571
Obesity 4 | 678
Prostate cancer 4 | 175
Short stature 4 | 531
Syndactyly 4 | 88
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
fibroadenoma 4 | 559
juvenile dermatomyositis 4 | 1,187
nasopharyngeal carcinoma 4 | 1,058
primary Sjogren syndrome 4 | 735
sarcoidosis 4 | 370
Alzheimer's disease 3 | 658
Bilateral fifth finger clinodactyly 3 | 110
Curvature of little finger 3 | 110
Depressive disorder 3 | 409
Duchenne muscular dystrophy 3 | 601
Epilepsy 3 | 792
Male infertility 3 | 206
Prostatic Neoplasms 3 | 495
Seizures 3 | 596
acute myeloid leukemia 3 | 783
astrocytoma 3 | 1,146
dermatomyositis 3 | 966
diabetes mellitus 3 | 1,728
head and neck cancer 3 | 271
primary pancreatic ductal adenocarcinoma 3 | 1,109
sonic hedgehog group medulloblastoma 3 | 467

Tissue

Endocrine System 66 | 18,159
Female tissues 64 | 17,400
Skin and soft tissues 64 | 17,230
Digestive Tract 63 | 17,369
Liver and Pancreas 62 | 16,750
Male tissues 62 | 17,142
Urinary Tract 62 | 16,678
Nervous System 61 | 16,725
Blood and immune system 59 | 16,909
Cardiovascular System 57 | 15,192
Respiratory system 55 | 16,393

Target Family

Non-IDG 43 | 12,091
Enzyme 11 | 4,145
Transcription Factor 5 | 1,400
Ion Channel 4 | 344
Transporter 4 | 473
Kinase 2 | 634
GPCR 1 | 408

GWAS Trait

Amyotrophic lateral sclerosis ... 70 | 70
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Calcium-activated potassium channel subunit beta-2 KCNMB2 Tbio Ion Channel 1.28 0.09 191
Probable RNA-binding protein 19 RBM19 Tbio Non-IDG -0.42051 3.55 37
Nuclear factor of activated T-cells, cytoplasmic 2 NFATC2 Tbio Transcription Factor -2.43207 259.4 365
Endothelial protein C receptor PROCR Tbio Non-IDG -2.70271 541.0 367
TFIIA-alpha and beta-like factor GTF2A1L Tbio Non-IDG -0.66901 3.86 222
Synaptopodin-2 SYNPO2 Tbio Non-IDG -1.31714 27.9 42
Sterile alpha and TIR motif-containing protein 1 SARM1 Tbio Non-IDG -2.22753 163.9 159
IQ domain-containing protein F5 IQCF5 Tdark Non-IDG 0.00000 3
Neurofascin NFASC Tbio Non-IDG -2.09540 119.2 154
Myelin-associated oligodendrocyte basic protein MOBP Tbio Non-IDG -1.36705 23.4 133