Development Level

Tbio 85 | 11,445
Tdark 24 | 6,588
Tchem 10 | 1,598
Tclin 5 | 613

Collection

Ion Channel: IDG Consortium (T... 1 | 99
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 9 | 979
preweaning lethality, incomple... 5 | 499
abnormal embryo size 4 | 220
abnormal behavior 3 | 298
cataract 3 | 92
increased startle reflex 3 | 112
persistence of hyaloid vascula... 3 | 33
abnormal cornea morphology 2 | 31
abnormal lens morphology 2 | 81
abnormal retina morphology 2 | 71
abnormal seminal vesicle morph... 2 | 114
cardiovascular system phenotyp... 2 | 36
decreased total body fat amoun... 2 | 207
decreased vertical activity 2 | 208
edema 2 | 59
enlarged heart 2 | 210
improved glucose tolerance 2 | 79
increased bone mineral content 2 | 108
increased circulating chloride... 2 | 41
increased total body fat amoun... 2 | 134
abnormal coat- hair morphology 1 | 19
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal locomotor behavior 1 | 24
abnormal optic disc morphology 1 | 10
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal testis morphology 1 | 43
abnormal vitreous body morphol... 1 | 10
corneal opacity 1 | 32
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating phosphat... 1 | 27
decreased circulating sodium l... 1 | 22
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased monocyte cell number 1 | 8
decreased neutrophil cell numb... 1 | 42
enlarged epididymis 1 | 31
fused cornea and lens 1 | 5
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired pupillary reflex 1 | 26
increased body temperature 1 | 9
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 28
increased erythrocyte cell num... 1 | 39
increased fasted circulating g... 1 | 76
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased mean platelet volume 1 | 45
increased or absent threshold ... 1 | 101
increased vertical activity 1 | 24
iris synechia 1 | 3
limb grasping 1 | 41
male infertility 1 | 123
narrow eye opening 1 | 12
prenatal lethality 1 | 28
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
short tibia 1 | 97
small adrenal glands 1 | 16
small spleen 1 | 19
small testis 1 | 58
thrombocytopenia 1 | 56
tremors 1 | 39
unresponsive to tactile stimul... 1 | 8

Disease

Carcinoma 90 | 11,493
ovarian cancer 64 | 8,520
osteosarcoma 59 | 7,950
glioblastoma 55 | 5,792
medulloblastoma, large-cell 54 | 6,241
psoriasis 54 | 6,694
atypical teratoid / rhabdoid tumor 51 | 5,112
ependymoma 47 | 4,679
lung cancer 40 | 4,740
Astrocytoma, Pilocytic 39 | 3,081
Breast cancer 39 | 3,578
Kidney cancer 38 | 2,613
malignant mesothelioma 38 | 3,232
lung adenocarcinoma 36 | 2,716
adult high grade glioma 35 | 3,801
group 3 medulloblastoma 31 | 4,104
oligodendroglioma 31 | 2,850
astrocytic glioma 30 | 2,597
pancreatic cancer 30 | 2,398
lung carcinoma 28 | 2,843
non-small cell lung cancer 28 | 2,890
pituitary cancer 27 | 1,972
primitive neuroectodermal tumor 27 | 3,035
invasive ductal carcinoma 25 | 2,951
intraductal papillary-mucinous neoplasm (IPMN) 24 | 3,291
interstitial cystitis 23 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 22 | 2,989
ductal carcinoma in situ 21 | 1,745
subependymal giant cell astrocytoma 21 | 2,287
intraductal papillary-mucinous adenoma (IPMA) 20 | 2,955
acute quadriplegic myopathy 19 | 1,158
Cancer 18 | 2,499
Pick disease 18 | 1,894
breast carcinoma 18 | 1,638
adrenocortical carcinoma 17 | 1,428
ulcerative colitis 17 | 1,819
Autosomal recessive predisposition 16 | 1,442
cystic fibrosis 15 | 1,696
medulloblastoma 15 | 720
nasopharyngeal carcinoma 15 | 1,058
Atopic dermatitis 14 | 952
Schizophrenia 14 | 1,160
colon cancer 14 | 1,478
group 4 medulloblastoma 14 | 1,855
primary pancreatic ductal adenocarcinoma 13 | 1,109
tuberculosis 13 | 2,010
Melanoma 12 | 711
acute myeloid leukemia 11 | 783
diabetes mellitus 11 | 1,728
pancreatic ductal adenocarcinoma liver metastasis 11 | 1,962
Autistic Disorder 10 | 364
Epilepsy 10 | 792
Liver cancer 10 | 604
dermatomyositis 10 | 966
esophageal adenocarcinoma 10 | 737
Alzheimer's disease 9 | 658
Intellectual disability 9 | 1,016
active Crohn's disease 9 | 922
active ulcerative colitis 9 | 764
gastric cancer 9 | 459
gastric carcinoma 9 | 807
juvenile dermatomyositis 9 | 1,187
pancreatic carcinoma 9 | 562
pediatric high grade glioma 9 | 1,064
primary Sjogren syndrome 9 | 735
Down syndrome 8 | 499
Duchenne muscular dystrophy 8 | 601
Muscle hypotonia 8 | 571
Obesity 8 | 678
Parkinson's disease 8 | 392
Waldenstrons macroglobulinemia 8 | 765
Amyotrophic lateral sclerosis 7 | 451
Cleft Palate 7 | 271
Kidney disease 7 | 430
Multiple myeloma 7 | 1,332
Rheumatoid arthritis 7 | 1,191
Skin cancer 7 | 469
chronic rhinosinusitis 7 | 512
fibroadenoma 7 | 559
non-small cell lung carcinoma 7 | 317
sonic hedgehog group medulloblastoma 7 | 467
Alcoholic Intoxication, Chronic 6 | 289
Cognitive delay 6 | 608
Global developmental delay 6 | 608
Liver Cirrhosis, Experimental 6 | 769
Mental and motor retardation 6 | 608
Seizures 6 | 596
Substance-Related Disorders 6 | 115
Vascular disease 6 | 319
astrocytoma 6 | 1,146
non primary Sjogren syndrome sicca 6 | 891
progressive supranuclear palsy 6 | 676
spina bifida 6 | 1,074
urothelial carcinoma 6 | 318
Dull intelligence 5 | 645
Low intelligence 5 | 645
Mental deficiency 5 | 645
Poor school performance 5 | 645
Prostatic Neoplasms 5 | 495
cutaneous lupus erythematosus 5 | 1,057

Tissue

Endocrine System 122 | 18,159
Female tissues 119 | 17,400
Nervous System 118 | 16,725
Digestive Tract 115 | 17,369
Skin and soft tissues 115 | 17,230
Male tissues 114 | 17,142
Liver and Pancreas 112 | 16,750
Urinary Tract 111 | 16,678
Respiratory system 110 | 16,393
Blood and immune system 108 | 16,909
Cardiovascular System 104 | 15,192

Target Family

Non-IDG 66 | 12,091
Enzyme 30 | 4,145
Transcription Factor 9 | 1,400
Ion Channel 5 | 344
GPCR 4 | 408
Kinase 3 | 634
Epigenetic 2 | 242
Nuclear Receptor 2 | 48
Transporter 2 | 473
TF/Epigenetic 1 | 38

GWAS Trait

Alzheimer disease and age of o... 124 | 124
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Calcium-dependent secretion activator 2 CADPS2 Tbio Non-IDG -1.18033 15.0 36
Phorbol-12-myristate-13-acetate-induced protein 1 PMAIP1 Tbio Non-IDG -2.70122 462.2 347
Beta-1,3-galactosyltransferase 1 B3GALT1 Tbio Enzyme -0.68296 3.85 66
Tetraspanin-16 TSPAN16 Tdark Non-IDG -1.99505 87.0 42
ATP-dependent RNA helicase DDX25 DDX25 Tbio Enzyme -1.23468 21.8 47
FERM, ARHGEF and pleckstrin domain-containing protein 1 FARP1 Tbio Non-IDG -1.56544 38.3 153
Annexin A10 ANXA10 Tbio Non-IDG -1.33040 25.3 301
Neurogenic differentiation factor 6 NEUROD6 Tbio Transcription Factor -1.51923 32.8 133
Nuclear envelope phosphatase-regulatory subunit 1 CNEP1R1 Tbio Enzyme 0.32 0.61 9
ATP-dependent RNA helicase DDX18 DDX18 Tbio Enzyme -0.74619 5.48 53