Development Level

Tbio 15 | 11,445
Tdark 5 | 6,588
Tchem 4 | 1,598
Tclin 1 | 613

IMPC Phenotype

increased fasted circulating g... 2 | 76
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal sleep behavior 1 | 70
abnormal snout morphology 1 | 23
convulsive seizures 1 | 13
decreased body length 1 | 101
decreased circulating alanine ... 1 | 47
decreased circulating insulin ... 1 | 76
decreased threshold for audito... 1 | 26
enlarged heart 1 | 210
enlarged testis 1 | 6
enlarged thymus 1 | 5
improved glucose tolerance 1 | 79
increased aggression 1 | 4
increased blood urea nitrogen ... 1 | 48
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased vertical activity 1 | 24
limb grasping 1 | 41
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 16 | 11,493
medulloblastoma, large-cell 13 | 6,241
psoriasis 12 | 6,694
glioblastoma 11 | 5,792
atypical teratoid / rhabdoid tumor 10 | 5,112
osteosarcoma 9 | 7,950
primitive neuroectodermal tumor 8 | 3,035
Cancer 7 | 2,499
ependymoma 7 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
lung cancer 7 | 4,740
lung carcinoma 7 | 2,843
ovarian cancer 7 | 8,520
subependymal giant cell astrocytoma 7 | 2,287
Alzheimer's disease 6 | 658
Astrocytoma, Pilocytic 6 | 3,081
adult high grade glioma 6 | 3,801
group 3 medulloblastoma 6 | 4,104
interstitial cystitis 6 | 2,312
malignant mesothelioma 6 | 3,232
non-small cell lung cancer 6 | 2,890
pituitary cancer 6 | 1,972
Pick disease 5 | 1,894
Schizophrenia 5 | 1,160
acute quadriplegic myopathy 5 | 1,158
astrocytoma 5 | 1,146
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
invasive ductal carcinoma 5 | 2,951
lung adenocarcinoma 5 | 2,716
pancreatic cancer 5 | 2,398
Alzheimer Disease 4 | 83
Breast cancer 4 | 3,578
group 4 medulloblastoma 4 | 1,855
juvenile dermatomyositis 4 | 1,187
oligodendroglioma 4 | 2,850
posterior fossa group A ependymoma 4 | 468
primary Sjogren syndrome 4 | 735
ulcerative colitis 4 | 1,819
Arthritis, Juvenile 3 | 126
Atopic dermatitis 3 | 952
Crohn's disease 3 | 321
Juvenile arthritis 3 | 126
Kidney cancer 3 | 2,613
Melanoma 3 | 711
adrenocortical carcinoma 3 | 1,428
astrocytic glioma 3 | 2,597
colon cancer 3 | 1,478
cystic fibrosis 3 | 1,696
esophageal adenocarcinoma 3 | 737
gastric cancer 3 | 459
hepatocellular carcinoma 3 | 547
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
tuberculosis 3 | 2,010
Acute kidney injury 2 | 70
Alcoholic Intoxication, Chronic 2 | 289
Amyloidosis 2 | 67
Anorexia nervosa 2 | 80
Atherosclerosis 2 | 291
Bipolar Disorder 2 | 666
Celiac disease 2 | 116
Chemical and Drug Induced Liver Injury 2 | 195
Chronic Lymphocytic Leukemia 2 | 262
Dementia 2 | 175
Duchenne muscular dystrophy 2 | 601
Endometriosis 2 | 540
Koolen de Vries syndrome 2 | 18
Lupus Erythematosus, Systemic 2 | 67
Panic disorder 2 | 61
Psychotic Disorders 2 | 151
Skin cancer 2 | 469
Vascular disease 2 | 319
active ulcerative colitis 2 | 764
chronic kidney disease 2 | 90
chronic lymphosyte leukemia 2 | 204
chronic rhinosinusitis 2 | 512
dermatomyositis 2 | 966
diabetes mellitus 2 | 1,728
ductal carcinoma in situ 2 | 1,745
medulloblastoma 2 | 720
nasopharyngeal carcinoma 2 | 1,058
pancreatic carcinoma 2 | 562
pediatric high grade glioma 2 | 1,064
periodontitis 2 | 293
post-traumatic stress disorder 2 | 40
AMYOTROPHIC LATERAL SCLEROSIS 1 1 | 49
Alcohol dependence 1 | 107
Arrhythmogenic right ventricular cardiomyopathy 1 | 30
Atrophic 1 | 10
Atrophy 1 | 10
Barrett's esophagus 1 | 182
Hemolytic anemia 1 | 77
Hyperactive behavior 1 | 91
Hypertrophy, Left Ventricular 1 | 24
Irritable bowel syndrome 1 | 60
Learning disability 1 | 17
Left Ventricular Hypertrophy 1 | 47
Perinatal necrotizing enterocolitis 1 | 21
Placental insufficiency 1 | 18
Pulmonary edema 1 | 17

Tissue

Endocrine System 25 | 18,159
Male tissues 25 | 17,142
Blood and immune system 24 | 16,909
Digestive Tract 24 | 17,369
Female tissues 24 | 17,400
Skin and soft tissues 23 | 17,230
Urinary Tract 23 | 16,678
Nervous System 22 | 16,725
Respiratory system 22 | 16,393
Liver and Pancreas 21 | 16,750
Cardiovascular System 20 | 15,192

Target Family

Non-IDG 18 | 12,091
Enzyme 2 | 4,145
Kinase 2 | 634
GPCR 1 | 408
Ion Channel 1 | 344
Transporter 1 | 473

GWAS Trait

Alzheimer's disease in APOE e4... 25 | 25
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Putative membrane-spanning 4-domains subfamily A member 4E MS4A4E Tdark Non-IDG -0.44037 2.73 6
Serine incorporator 5 SERINC5 Tbio Non-IDG -1.50535 34.0 11
Cerebellar degeneration-related protein 2-like CDR2L Tbio Non-IDG -1.07065 9.41 51
Long-chain-fatty-acid--CoA ligase 6 ACSL6 Tbio Enzyme -1.86749 73.8 139
Protein HID1 HID1 Tdark Non-IDG 0.18 0.96 127
Sodium/potassium/calcium exchanger 4 SLC24A4 Tbio Transporter -1.32054 20.8 63
Leucine-rich repeat-containing protein 37A LRRC37A Tdark Non-IDG -0.25710 1.63 17
Folliculin-interacting protein 1 FNIP1 Tbio Non-IDG -0.92010 6.73 74
O-acetyl-ADP-ribose deacetylase MACROD2 MACROD2 Tbio Enzyme -1.21785 14.5 19
Meiosis-specific kinetochore protein MEIKIN Tdark Non-IDG 0.00000 3