Development Level

Tbio 35 | 11,445
Tdark 6 | 6,588
Tchem 2 | 1,598
Tclin 1 | 613

Collection

Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

decreased circulating glucose ... 3 | 126
preweaning lethality, complete... 3 | 979
abnormal behavior 2 | 298
decreased vertical activity 2 | 208
increased fasted circulating g... 2 | 76
preweaning lethality, incomple... 2 | 499
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal snout morphology 1 | 23
absent pinna reflex 1 | 23
absent startle reflex 1 | 24
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased basophil cell number 1 | 16
decreased circulating free fat... 1 | 31
decreased eosinophil cell numb... 1 | 24
decreased mean corpuscular hem... 1 | 50
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged epididymis 1 | 31
enlarged heart 1 | 210
enlarged thymus 1 | 5
hyperactivity 1 | 148
increased aggression 1 | 4
increased body length 1 | 32
increased body weight 1 | 25
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased circulating sodium l... 1 | 71
increased heart rate variabili... 1 | 7
increased vertical activity 1 | 24
limb grasping 1 | 41

Disease

Carcinoma 32 | 11,493
osteosarcoma 26 | 7,950
Alzheimer's disease 25 | 658
ovarian cancer 25 | 8,520
glioblastoma 22 | 5,792
psoriasis 22 | 6,694
lung cancer 20 | 4,740
lung carcinoma 17 | 2,843
medulloblastoma, large-cell 17 | 6,241
atypical teratoid / rhabdoid tumor 16 | 5,112
lung adenocarcinoma 16 | 2,716
invasive ductal carcinoma 15 | 2,951
Astrocytoma, Pilocytic 14 | 3,081
non-small cell lung cancer 14 | 2,890
ependymoma 13 | 4,679
oligodendroglioma 13 | 2,850
Breast cancer 12 | 3,578
Kidney cancer 12 | 2,613
malignant mesothelioma 12 | 3,232
group 3 medulloblastoma 11 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
Cancer 10 | 2,499
pituitary cancer 10 | 1,972
subependymal giant cell astrocytoma 10 | 2,287
Alzheimer Disease 9 | 83
adult high grade glioma 9 | 3,801
ductal carcinoma in situ 9 | 1,745
nasopharyngeal carcinoma 9 | 1,058
primitive neuroectodermal tumor 9 | 3,035
tuberculosis 9 | 2,010
astrocytic glioma 8 | 2,597
colon cancer 8 | 1,478
group 4 medulloblastoma 8 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
astrocytoma 7 | 1,146
breast carcinoma 7 | 1,638
dermatomyositis 7 | 966
Atopic dermatitis 6 | 952
Waldenstrons macroglobulinemia 6 | 765
interstitial cystitis 6 | 2,312
ulcerative colitis 6 | 1,819
Cardiovascular system disease 5 | 246
Melanoma 5 | 711
Multiple myeloma 5 | 1,332
Osteoporosis 5 | 363
Pick disease 5 | 1,894
Vascular disease 5 | 319
active Crohn's disease 5 | 922
acute quadriplegic myopathy 5 | 1,158
cutaneous lupus erythematosus 5 | 1,057
cystic fibrosis 5 | 1,696
diabetes mellitus 5 | 1,728
juvenile dermatomyositis 5 | 1,187
pediatric high grade glioma 5 | 1,064
primary Sjogren syndrome 5 | 735
spina bifida 5 | 1,074
Dementia 4 | 175
Duchenne muscular dystrophy 4 | 601
Neurodegenerative disease 4 | 414
Rheumatoid arthritis 4 | 1,191
Schizophrenia 4 | 1,160
adrenocortical carcinoma 4 | 1,428
Amyloidosis 3 | 67
Amyotrophic lateral sclerosis 3 | 451
Atherosclerosis 3 | 291
Autism spectrum disorder 3 | 101
Chronic Lymphocytic Leukemia 3 | 262
Cognitive disorder 3 | 50
Down syndrome 3 | 499
Kidney disease 3 | 430
Macular degeneration 3 | 65
Seizures 3 | 596
Skin cancer 3 | 469
active ulcerative colitis 3 | 764
acute myeloid leukemia 3 | 783
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
esophageal adenocarcinoma 3 | 737
fibroadenoma 3 | 559
mucosa-associated lymphoid tissue lymphoma 3 | 484
pancreatic cancer 3 | 2,398
posterior fossa group A ependymoma 3 | 468
Anemia 2 | 365
Arthritis, Juvenile 2 | 126
Endometrial cancer 2 | 311
Epilepsy 2 | 792
Hypothyroidism 2 | 122
Juvenile arthritis 2 | 126
Major Depressive Disorder 2 | 301
Neoplasm Invasiveness 2 | 161
Polycystic ovary syndrome 2 | 360
Prostatic Neoplasms 2 | 495
Status Epilepticus 2 | 98
Type 2 diabetes mellitus 2 | 272
Unipolar Depression 2 | 250
aldosterone-producing adenoma 2 | 665
chronic rhinosinusitis 2 | 512
gastric carcinoma 2 | 807
hepatocellular carcinoma 2 | 547

Tissue

Blood and immune system 44 | 16,909
Digestive Tract 44 | 17,369
Endocrine System 44 | 18,159
Female tissues 44 | 17,400
Liver and Pancreas 44 | 16,750
Urinary Tract 44 | 16,678
Male tissues 43 | 17,142
Respiratory system 43 | 16,393
Skin and soft tissues 43 | 17,230
Nervous System 42 | 16,725
Cardiovascular System 41 | 15,192

Target Family

Non-IDG 31 | 12,091
Enzyme 6 | 4,145
Kinase 2 | 634
Transporter 2 | 473
Epigenetic 1 | 242
Ion Channel 1 | 344
Transcription Factor 1 | 1,400

GWAS Trait

Alzheimer's disease (late onse... 44 | 44
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
CD2-associated protein CD2AP Tbio Non-IDG -3.44533 2735.9 82
Putative membrane-spanning 4-domains subfamily A member 4E MS4A4E Tdark Non-IDG -0.44037 2.73 6
Leiomodin-3 LMOD3 Tbio Non-IDG -1.00928 10.3 27
Contactin-associated protein-like 2 CNTNAP2 Tbio Non-IDG -2.36156 228.4 191
FERM domain-containing protein 4B FRMD4B Tdark Non-IDG -0.63178 4.93 32
Complement receptor type 1 CR1 Tbio Non-IDG -3.36509 2362.6 700
Zinc finger CW-type PWWP domain protein 1 ZCWPW1 Tdark Epigenetic -0.64243 4.08 44
Apolipoprotein C-I APOC1 Tbio Non-IDG -2.39715 256.4 274
Bone morphogenetic protein 2 BMP2 Tbio Non-IDG -3.65728 4647.9 684
GRB2-associated-binding protein 2 GAB2 Tbio Non-IDG -2.08460 139.8 494