Development Level

Tbio 30 | 11,651
Tdark 5 | 6,593
Tchem 4 | 1,388
Tclin 2 | 612

IMPC Phenotype

decreased circulating glucose ... 2 | 126
abnormal behavior 1 | 298
abnormal tooth morphology 1 | 24
absent startle reflex 1 | 24
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased erythrocyte cell num... 1 | 62
hyperactivity 1 | 148
increased aggression 1 | 4
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased circulating triglyce... 1 | 42
increased fasted circulating g... 1 | 76
increased heart rate variabili... 1 | 7
increased mean corpuscular hem... 1 | 36
increased total body fat amoun... 1 | 134
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499

Disease

Alzheimer's disease 28 | 658
Carcinoma 26 | 11,493
osteosarcoma 23 | 7,950
glioblastoma 20 | 5,792
psoriasis 20 | 6,694
medulloblastoma, large-cell 19 | 6,241
ovarian cancer 18 | 8,520
atypical teratoid / rhabdoid tumor 15 | 5,112
intraductal papillary-mucinous neoplasm (IPMN) 15 | 3,291
lung cancer 15 | 4,740
adult high grade glioma 14 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 14 | 2,955
invasive ductal carcinoma 14 | 2,951
non-small cell lung cancer 14 | 2,890
Breast cancer 12 | 3,578
Cancer 12 | 2,499
interstitial cystitis 12 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,989
lung carcinoma 12 | 2,843
lung adenocarcinoma 11 | 2,716
ulcerative colitis 11 | 1,819
Alzheimer Disease 10 | 83
group 3 medulloblastoma 10 | 4,104
malignant mesothelioma 10 | 3,232
nasopharyngeal carcinoma 10 | 1,058
Astrocytoma, Pilocytic 9 | 3,081
Kidney cancer 9 | 2,613
ductal carcinoma in situ 9 | 1,745
oligodendroglioma 9 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
subependymal giant cell astrocytoma 9 | 2,287
Schizophrenia 8 | 1,160
astrocytoma 8 | 1,146
cutaneous lupus erythematosus 8 | 1,057
cystic fibrosis 8 | 1,696
ependymoma 8 | 4,679
pituitary cancer 8 | 1,972
primitive neuroectodermal tumor 8 | 3,035
Intellectual disability 7 | 1,016
Seizures 7 | 596
astrocytic glioma 7 | 2,597
colon cancer 7 | 1,478
juvenile dermatomyositis 7 | 1,187
pancreatic cancer 7 | 2,398
Atopic dermatitis 6 | 952
Autosomal recessive predisposition 6 | 1,442
Bipolar Disorder 6 | 666
Dementia 6 | 175
Duchenne muscular dystrophy 6 | 601
Pick disease 6 | 1,894
adrenocortical carcinoma 6 | 1,428
breast carcinoma 6 | 1,638
group 4 medulloblastoma 6 | 1,855
tuberculosis 6 | 2,010
Atherosclerosis 5 | 291
Endometriosis 5 | 540
Epilepsy 5 | 792
Kidney disease 5 | 430
Major Depressive Disorder 5 | 301
Multiple Sclerosis 5 | 540
Waldenstrons macroglobulinemia 5 | 765
acute quadriplegic myopathy 5 | 1,158
diabetes mellitus 5 | 1,728
head and neck cancer and chronic obstructive pulmonary disease 5 | 239
mucosa-associated lymphoid tissue lymphoma 5 | 484
Cognitive disorder 4 | 50
Dull intelligence 4 | 645
Liver cancer 4 | 604
Low intelligence 4 | 645
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Multiple myeloma 4 | 1,332
Poor school performance 4 | 645
Unipolar Depression 4 | 250
aldosterone-producing adenoma 4 | 665
chronic rhinosinusitis 4 | 512
esophageal adenocarcinoma 4 | 737
non primary Sjogren syndrome sicca 4 | 891
primary Sjogren syndrome 4 | 735
Anemia 3 | 365
Arthritis, Juvenile 3 | 126
Autism spectrum disorder 3 | 101
Autistic Disorder 3 | 364
Cardiovascular system disease 3 | 246
Coronary artery disease 3 | 268
DOID:2627 3 | 94
Depressive disorder 3 | 409
Endometrial cancer 3 | 311
Hypertension 3 | 396
Juvenile arthritis 3 | 126
Melanoma 3 | 711
Mood Disorders 3 | 184
Neurodegenerative disease 3 | 414
Obesity 3 | 678
Vascular disease 3 | 319
dermatomyositis 3 | 966
hepatocellular carcinoma 3 | 547
pediatric high grade glioma 3 | 1,064
periodontitis 3 | 293
spina bifida 3 | 1,074

Tissue

Endocrine System 40 | 18,159
Blood and immune system 39 | 16,909
Female tissues 39 | 17,400
Liver and Pancreas 39 | 16,750
Digestive Tract 38 | 17,369
Male tissues 38 | 17,142
Skin and soft tissues 38 | 17,230
Urinary Tract 38 | 16,678
Nervous System 37 | 16,725
Respiratory system 37 | 16,393
Cardiovascular System 34 | 15,192

Target Family

Non-IDG 29 | 12,091
Enzyme 6 | 4,145
Transporter 3 | 473
Transcription Factor 2 | 1,400
Kinase 1 | 634

GWAS Trait

Alzheimer's disease 41 | 41
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein phosphatase 1 regulatory subunit 3B PPP1R3B Tbio Enzyme -2.49697 300.9 94
FANCD2 opposite strand protein FANCD2OS Tdark Non-IDG 0.00000 50
Triggering receptor expressed on myeloid cells 2 TREM2 Tbio Non-IDG -2.42594 269.9 370
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 NDUFA12 Tclin Enzyme -0.98410 9.07 112
Phosphatidylinositol-binding clathrin assembly protein PICALM Tbio Non-IDG -1.92862 84.7 130
Apolipoprotein E APOE Tbio Non-IDG -4.20176 15904.9 976
ATP-binding cassette sub-family A member 7 ABCA7 Tbio Transporter -2.20287 157.0 138
Myeloid cell surface antigen CD33 CD33 Tclin Non-IDG -2.92768 774.4 1518
Clusterin CLU Tbio Non-IDG -3.28651 2016.4 826
Stromelysin-1 MMP3 Tchem Non-IDG -3.28189 1799.2 1019