Development Level

Tbio 86 | 11,445
Tchem 14 | 1,598
Tdark 9 | 6,588
Tclin 6 | 613

IMPC Phenotype

preweaning lethality, complete... 5 | 979
preweaning lethality, incomple... 3 | 499
abnormal bone structure 2 | 187
decreased bone mineral content 2 | 151
decreased bone mineral density 2 | 126
decreased circulating creatini... 2 | 39
decreased mean corpuscular vol... 2 | 79
embryonic lethality prior to o... 2 | 239
enlarged heart 2 | 210
hypoactivity 2 | 132
improved glucose tolerance 2 | 79
abnormal behavior 1 | 298
abnormal coat- hair morphology 1 | 19
abnormal colon morphology 1 | 3
abnormal duodenum morphology 1 | 4
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal eye anterior chamber ... 1 | 9
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal locomotor behavior 1 | 24
abnormal sleep behavior 1 | 70
abnormal spleen morphology 1 | 55
abnormal vertebrae morphology 1 | 18
abnormal vibrissa morphology 1 | 25
decreased NK T cell number 1 | 2
decreased anxiety-related resp... 1 | 12
decreased body length 1 | 101
decreased caudal vertebrae num... 1 | 53
decreased circulating chloride... 1 | 30
decreased circulating insulin ... 1 | 76
decreased heart weight 1 | 27
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 50
decreased respiratory quotient 1 | 16
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
embryonic lethality prior to t... 1 | 278
enlarged epididymis 1 | 31
enlarged lymph nodes 1 | 37
enlarged testis 1 | 6
hemorrhage 1 | 23
increased body length 1 | 32
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased heart rate 1 | 23
increased heart weight 1 | 62
increased lean body mass 1 | 172
increased or absent threshold ... 1 | 101
short tibia 1 | 97
unresponsive to tactile stimul... 1 | 8

Disease

Carcinoma 80 | 11,493
osteosarcoma 61 | 7,950
psoriasis 59 | 6,694
ovarian cancer 56 | 8,520
lung cancer 44 | 4,740
glioblastoma 43 | 5,792
Breast cancer 41 | 3,578
Cancer 39 | 2,499
medulloblastoma, large-cell 39 | 6,241
tuberculosis 33 | 2,010
atypical teratoid / rhabdoid tumor 31 | 5,112
malignant mesothelioma 31 | 3,232
group 3 medulloblastoma 30 | 4,104
lung carcinoma 29 | 2,843
non-small cell lung cancer 29 | 2,890
Astrocytoma, Pilocytic 28 | 3,081
adult high grade glioma 28 | 3,801
invasive ductal carcinoma 28 | 2,951
ependymoma 27 | 4,679
ulcerative colitis 27 | 1,819
intraductal papillary-mucinous neoplasm (IPMN) 25 | 3,291
lung adenocarcinoma 24 | 2,716
Rheumatoid arthritis 23 | 1,191
interstitial cystitis 23 | 2,312
subependymal giant cell astrocytoma 23 | 2,287
pituitary cancer 21 | 1,972
Crohn's disease 20 | 321
intraductal papillary-mucinous carcinoma (IPMC) 20 | 2,989
Kidney cancer 19 | 2,613
Multiple Sclerosis 19 | 540
intraductal papillary-mucinous adenoma (IPMA) 19 | 2,955
primitive neuroectodermal tumor 19 | 3,035
Asthma 18 | 385
Pick disease 17 | 1,894
cystic fibrosis 17 | 1,696
pancreatic cancer 17 | 2,398
Atopic dermatitis 16 | 952
cutaneous lupus erythematosus 16 | 1,057
pancreatic ductal adenocarcinoma liver metastasis 16 | 1,962
astrocytic glioma 15 | 2,597
spina bifida 15 | 1,074
Hypersensitivity reaction type II disease 14 | 253
dermatomyositis 13 | 966
group 4 medulloblastoma 13 | 1,855
Autosomal recessive predisposition 12 | 1,442
Inflammatory bowel disease 12 | 151
Type 1 diabetes mellitus 12 | 109
diabetes mellitus 12 | 1,728
ductal carcinoma in situ 12 | 1,745
oligodendroglioma 12 | 2,850
primary Sjogren syndrome 12 | 735
Liver Cirrhosis, Experimental 11 | 769
acute quadriplegic myopathy 11 | 1,158
colon cancer 11 | 1,478
Allergic hypersensitivity disease 10 | 126
Allergic rhinitis 10 | 94
Alzheimer's disease 10 | 658
Celiac disease 10 | 116
Epilepsy 10 | 792
Schizophrenia 10 | 1,160
Common variable immunodeficiency 9 | 101
Dermatitis, Atopic 9 | 37
Seizures 9 | 596
Systemic lupus erythematosus 9 | 194
astrocytoma 9 | 1,146
esophageal adenocarcinoma 9 | 737
Hepatomegaly 8 | 285
Hypereosinophilic syndrome 8 | 71
Intellectual disability 8 | 1,016
Multiple myeloma 8 | 1,332
Vitiligo 8 | 73
Waldenstrons macroglobulinemia 8 | 765
aldosterone-producing adenoma 8 | 665
juvenile dermatomyositis 8 | 1,187
pediatric high grade glioma 8 | 1,064
periodontitis 8 | 293
Acquired metabolic disease 7 | 336
Alopecia areata 7 | 41
Anemia 7 | 365
Arthritis 7 | 290
Dull intelligence 7 | 645
Endometriosis 7 | 540
Fever 7 | 138
Kidney disease 7 | 430
Leukemia, Myelocytic, Acute 7 | 120
Low intelligence 7 | 645
Lupus Erythematosus, Systemic 7 | 67
Melanoma 7 | 711
Mental Retardation 7 | 645
Mental deficiency 7 | 645
Pneumonia 7 | 174
Poor school performance 7 | 645
active ulcerative colitis 7 | 764
breast carcinoma 7 | 1,638
gastric carcinoma 7 | 807
Arthritis, Rheumatoid 6 | 174
Cognitive delay 6 | 608
Mental and motor retardation 6 | 608
Prostatic Neoplasms 6 | 495
Vascular disease 6 | 319

Tissue

Digestive Tract 111 | 17,369
Blood and immune system 108 | 16,909
Endocrine System 108 | 18,159
Female tissues 107 | 17,400
Liver and Pancreas 107 | 16,750
Male tissues 107 | 17,142
Urinary Tract 107 | 16,678
Skin and soft tissues 106 | 17,230
Nervous System 103 | 16,725
Respiratory system 103 | 16,393
Cardiovascular System 96 | 15,192

Target Family

Non-IDG 57 | 12,091
Transcription Factor 22 | 1,400
Enzyme 21 | 4,145
Kinase 5 | 634
Transporter 3 | 473
Epigenetic 2 | 242
GPCR 2 | 408
Nuclear Receptor 2 | 48
Ion Channel 1 | 344

GWAS Trait

Allergic disease (asthma, hay ... 115 | 115
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tumor necrosis factor receptor superfamily member 11A TNFRSF11A Tbio Non-IDG -3.26478 1689.0 464
NEDD4 family-interacting protein 1 NDFIP1 Tbio Non-IDG -1.24333 24.3 147
Juxtaposed with another zinc finger protein 1 JAZF1 Tbio Non-IDG -1.61585 42.8 94
C-C motif chemokine 20 CCL20 Tbio Non-IDG -3.10283 1250.3 496
Inactive ubiquitin thioesterase FAM105A FAM105A Tdark Enzyme -0.38641 2.48 94
Interleukin-1 receptor-like 1 IL1RL1 Tbio Non-IDG -2.06895 107.0 347
Nuclear factor of activated T-cells, cytoplasmic 2 NFATC2 Tbio Transcription Factor -2.43207 259.4 365
Forkhead box protein O1 FOXO1 Tbio Transcription Factor -3.05358 1143.3 1478
Regulator of G-protein signaling 14 RGS14 Tbio Non-IDG -1.61170 43.9 233
Transcription regulator protein BACH2 BACH2 Tbio Transcription Factor -1.90906 89.8 184