Development Level

Tbio 35 | 11,445
Tdark 6 | 6,588
Tclin 5 | 613
Tchem 2 | 1,598

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal gait 2 | 69
embryonic lethality prior to t... 2 | 278
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal embryo size 1 | 220
abnormal lens morphology 1 | 81
abnormal locomotor behavior 1 | 24
abnormal optic disc morphology 1 | 10
abnormal response to tactile s... 1 | 17
abnormal retinal blood vessel ... 1 | 26
abnormal startle reflex 1 | 15
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alkaline... 1 | 46
decreased circulating aspartat... 1 | 34
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating potassiu... 1 | 20
decreased circulating total pr... 1 | 49
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
head bobbing 1 | 5
increased body weight 1 | 25
increased prepulse inhibition 1 | 32
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97
thrombocytopenia 1 | 56

Disease

Carcinoma 36 | 11,493
ovarian cancer 33 | 8,520
psoriasis 25 | 6,694
atypical teratoid / rhabdoid tumor 23 | 5,112
glioblastoma 23 | 5,792
osteosarcoma 21 | 7,950
adult high grade glioma 17 | 3,801
lung cancer 17 | 4,740
substance-related disorder 17 | 162
malignant mesothelioma 16 | 3,232
Astrocytoma, Pilocytic 15 | 3,081
Breast cancer 15 | 3,578
Kidney cancer 15 | 2,613
ependymoma 15 | 4,679
invasive ductal carcinoma 15 | 2,951
pituitary cancer 14 | 1,972
lung carcinoma 13 | 2,843
medulloblastoma, large-cell 13 | 6,241
non-small cell lung cancer 13 | 2,890
intraductal papillary-mucinous adenoma (IPMA) 12 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
ductal carcinoma in situ 11 | 1,745
group 3 medulloblastoma 10 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
oligodendroglioma 10 | 2,850
pancreatic cancer 10 | 2,398
primitive neuroectodermal tumor 10 | 3,035
Pick disease 9 | 1,894
astrocytic glioma 9 | 2,597
breast carcinoma 9 | 1,638
lung adenocarcinoma 9 | 2,716
subependymal giant cell astrocytoma 9 | 2,287
Cancer 8 | 2,499
Schizophrenia 8 | 1,160
group 4 medulloblastoma 8 | 1,855
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
Alcohol dependence 7 | 107
Alcoholic Intoxication, Chronic 7 | 289
colon cancer 7 | 1,478
tuberculosis 7 | 2,010
active Crohn's disease 6 | 922
acute quadriplegic myopathy 6 | 1,158
interstitial cystitis 6 | 2,312
pediatric high grade glioma 6 | 1,064
Atopic dermatitis 5 | 952
Bipolar Disorder 5 | 666
Multiple myeloma 5 | 1,332
adrenocortical carcinoma 5 | 1,428
astrocytoma 5 | 1,146
cystic fibrosis 5 | 1,696
fibroadenoma 5 | 559
primary pancreatic ductal adenocarcinoma 5 | 1,109
Acquired metabolic disease 4 | 336
Alcohol abuse 4 | 50
Autosomal recessive predisposition 4 | 1,442
Intellectual disability 4 | 1,016
Liver disease 4 | 237
active ulcerative colitis 4 | 764
diabetes mellitus 4 | 1,728
esophageal cancer 4 | 22
gastric carcinoma 4 | 807
non primary Sjogren syndrome sicca 4 | 891
posterior fossa group A ependymoma 4 | 468
ulcerative colitis 4 | 1,819
Alcoholic Intoxication 3 | 34
Alcoholism 3 | 45
Alzheimer's disease 3 | 658
Anteverted nostril 3 | 191
Cognitive delay 3 | 608
Esophageal Neoplasms 3 | 69
Essential Hypertension 3 | 94
Genetic Predisposition to Disease 3 | 27
Global developmental delay 3 | 608
Liver Cirrhosis, Experimental 3 | 769
Mental and motor retardation 3 | 608
Migraine Disorders 3 | 76
Obesity 3 | 678
Pancreatitis 3 | 123
Rheumatoid arthritis 3 | 1,191
Substance abuse 3 | 59
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
juvenile dermatomyositis 3 | 1,187
mucosa-associated lymphoid tissue lymphoma 3 | 484
nasopharyngeal carcinoma 3 | 1,058
pancreatic carcinoma 3 | 562
sonic hedgehog group medulloblastoma 3 | 467
Attention deficit hyperactivity disorder 2 | 278
Depressive disorder 2 | 409
Endometriosis 2 | 540
Infertility, Male 2 | 46
Male infertility 2 | 206
Mental Depression 2 | 333
Prostate cancer 2 | 175
Type 2 diabetes mellitus 2 | 272
Vascular disease 2 | 319
aldosterone-producing adenoma 2 | 665
dermatomyositis 2 | 966
esophageal adenocarcinoma 2 | 737
hepatocellular carcinoma 2 | 547
spina bifida 2 | 1,074

Tissue

Endocrine System 46 | 18,159
Male tissues 46 | 17,142
Digestive Tract 45 | 17,369
Female tissues 45 | 17,400
Nervous System 45 | 16,725
Skin and soft tissues 45 | 17,230
Cardiovascular System 44 | 15,192
Liver and Pancreas 44 | 16,750
Urinary Tract 44 | 16,678
Blood and immune system 43 | 16,909
Respiratory system 42 | 16,393

Target Family

Non-IDG 27 | 12,091
Enzyme 14 | 4,145
Transcription Factor 3 | 1,400
Epigenetic 1 | 242
Ion Channel 1 | 344
Kinase 1 | 634
Nuclear Receptor 1 | 48

GWAS Trait

Alcohol dependence 48 | 48
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Estrogen receptor ESR1 Tclin Nuclear Receptor -4.00480 8421.6 2610
Ammonium transporter Rh type A RHAG Tbio Non-IDG -3.03053 1073.1 38
Aldehyde dehydrogenase, mitochondrial ALDH2 Tclin Enzyme -2.97865 1004.9 470
SH3 domain-binding protein 5 SH3BP5 Tbio Non-IDG -2.76639 566.7 116
Runt-related transcription factor 3 RUNX3 Tbio Transcription Factor -2.71721 536.2 438
Contactin-5 CNTN5 Tbio Non-IDG -2.54880 296.6 100
Gamma-sarcoglycan SGCG Tbio Non-IDG -2.52283 333.0 85
Alcohol dehydrogenase 1B ADH1B Tclin Enzyme -2.42307 381.5 160
Alcohol dehydrogenase 1C ADH1C Tclin Enzyme -2.42307 381.5 97
Histone deacetylase 4 HDAC4 Tclin Epigenetic -2.42231 255.5 825