Development Level

Tbio 25 | 11,445
Tchem 6 | 1,598
Tclin 1 | 613
Tdark 1 | 6,588

Collection

Ion Channel: IDG Consortium (T... 1 | 99
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 3 | 979
decreased body length 2 | 101
enlarged heart 2 | 210
hyperactivity 2 | 148
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal eye morphology 1 | 68
abnormal heart morphology 1 | 162
abnormal lymph node morphology 1 | 3
abnormal seminal vesicle morph... 1 | 114
absent startle reflex 1 | 24
aorta stenosis 1 | 2
cataract 1 | 92
convulsive seizures 1 | 13
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased heart left ventricle... 1 | 28
decreased heart rate 1 | 18
decreased mean corpuscular vol... 1 | 79
decreased mean platelet volume 1 | 25
decreased threshold for audito... 1 | 26
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
enlarged spleen 1 | 41
hypoactivity 1 | 132
increased circulating sodium l... 1 | 71
increased erythrocyte cell num... 1 | 39
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 96
persistence of hyaloid vascula... 1 | 33
preweaning lethality, incomple... 1 | 499
thin ventricular wall 1 | 24
thrombocytopenia 1 | 56

Disease

Macular degeneration 26 | 65
Carcinoma 21 | 11,493
ovarian cancer 18 | 8,520
lung cancer 15 | 4,740
psoriasis 15 | 6,694
glioblastoma 13 | 5,792
osteosarcoma 13 | 7,950
Age related macular degeneration 12 | 72
Breast cancer 12 | 3,578
malignant mesothelioma 12 | 3,232
lung carcinoma 11 | 2,843
non-small cell lung cancer 11 | 2,890
ependymoma 10 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,955
invasive ductal carcinoma 9 | 2,951
medulloblastoma, large-cell 9 | 6,241
Autosomal recessive predisposition 8 | 1,442
Cancer 8 | 2,499
adult high grade glioma 8 | 3,801
ductal carcinoma in situ 8 | 1,745
Astrocytoma, Pilocytic 7 | 3,081
Kidney cancer 7 | 2,613
Kidney disease 7 | 430
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
lung adenocarcinoma 7 | 2,716
subependymal giant cell astrocytoma 7 | 2,287
astrocytoma 6 | 1,146
atypical teratoid / rhabdoid tumor 6 | 5,112
breast carcinoma 6 | 1,638
cystic fibrosis 6 | 1,696
diabetes mellitus 6 | 1,728
group 3 medulloblastoma 6 | 4,104
interstitial cystitis 6 | 2,312
oligodendroglioma 6 | 2,850
pancreatic cancer 6 | 2,398
Kuhnt-Junius degeneration 5 | 14
Melanoma 5 | 711
Rheumatoid arthritis 5 | 1,191
Schizophrenia 5 | 1,160
colon cancer 5 | 1,478
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
ulcerative colitis 5 | 1,819
Alopecia areata 4 | 41
Atypical Hemolytic Uremic Syndrome 4 | 9
Cardiovascular system disease 4 | 246
Coronary artery disease 4 | 268
Hemolytic-Uremic Syndrome 4 | 30
Immunologic Deficiency Syndromes 4 | 113
Liver cancer 4 | 604
Multiple Sclerosis 4 | 540
Systemic lupus erythematosus 4 | 194
Thrombocytopenia 4 | 197
Type 1 diabetes mellitus 4 | 109
Type 2 diabetes mellitus 4 | 272
active Crohn's disease 4 | 922
adrenocortical carcinoma 4 | 1,428
aldosterone-producing adenoma 4 | 665
astrocytic glioma 4 | 2,597
dermatomyositis 4 | 966
juvenile dermatomyositis 4 | 1,187
nasopharyngeal carcinoma 4 | 1,058
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
pituitary cancer 4 | 1,972
primary pancreatic ductal adenocarcinoma 4 | 1,109
tuberculosis 4 | 2,010
Acquired metabolic disease 3 | 336
Alzheimer's disease 3 | 658
Anemia 3 | 365
Atherosclerosis 3 | 291
Bipolar Disorder 3 | 666
Cerebrovascular disease 3 | 238
Duchenne muscular dystrophy 3 | 601
Hypertension 3 | 396
Major Depressive Disorder 3 | 301
Metabolic syndrome X 3 | 52
Nonorganic psychosis 3 | 84
Obesity 3 | 678
Orbital separation excessive 3 | 244
Prostate cancer 3 | 175
Psychotic Disorders 3 | 151
Skin Neoplasms 3 | 69
Skin cancer 3 | 469
Systemic scleroderma 3 | 60
Vascular disease 3 | 319
Vitiligo 3 | 73
acute quadriplegic myopathy 3 | 1,158
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
fibroadenoma 3 | 559
gastric carcinoma 3 | 807
non primary Sjogren syndrome sicca 3 | 891
pediatric high grade glioma 3 | 1,064
periodontitis 3 | 293
primitive neuroectodermal tumor 3 | 3,035
urothelial carcinoma 3 | 318
Chronic obstructive pulmonary disease 2 | 184
Craniosynostosis 2 | 74
Diabetes Mellitus, Non-Insulin-Dependent 2 | 145
Diabetes Mellitus, Type 2 2 | 142
Epilepsy 2 | 792
Ventricular Septal Defects 2 | 119

Tissue

Endocrine System 33 | 18,159
Female tissues 33 | 17,400
Skin and soft tissues 33 | 17,230
Blood and immune system 32 | 16,909
Cardiovascular System 32 | 15,192
Digestive Tract 32 | 17,369
Liver and Pancreas 32 | 16,750
Male tissues 32 | 17,142
Respiratory system 31 | 16,393
Urinary Tract 31 | 16,678
Nervous System 30 | 16,725

Target Family

Non-IDG 18 | 12,091
Enzyme 6 | 4,145
Kinase 4 | 634
Transcription Factor 3 | 1,400
Ion Channel 1 | 344
Transporter 1 | 473

GWAS Trait

Age-related macular degenerati... 33 | 33
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Collagen alpha-1(VIII) chain COL8A1 Tbio Non-IDG -1.31054 16.6 116
Hematopoietic progenitor cell antigen CD34 CD34 Tbio Non-IDG -4.14691 13698.4 1952
Tyrosine-protein kinase FRK FRK Tchem Kinase -1.68365 49.2 394
Death-associated protein kinase 3 DAPK3 Tchem Kinase -1.64668 50.7 291
Tyrosinase TYR Tclin Enzyme -3.32888 2021.2 494
Apolipoprotein C-I APOC1 Tbio Non-IDG -2.39715 256.4 274
Cholesteryl ester transfer protein CETP Tchem Non-IDG -3.20658 1755.9 264
Mitochondrial import receptor subunit TOM40 homolog TOMM40 Tbio Non-IDG -2.21973 158.9 94
Synapsin-3 SYN3 Tbio Non-IDG -1.99912 100.6 110
Ras-responsive element-binding protein 1 RREB1 Tbio Transcription Factor -1.67112 45.9 157