Development Level

Tbio 8 | 11,445

IMPC Phenotype

abnormal lens morphology 2 | 81
cataract 2 | 92

Disease

Breast cancer 6 | 3,578
Carcinoma 6 | 11,493
osteosarcoma 6 | 7,950
ovarian cancer 6 | 8,520
Lymphoid leukemia 5 | 160
lung cancer 5 | 4,740
Cancer 4 | 2,499
Precursor Cell Lymphoblastic Leukemia Lymphoma 4 | 43
Precursor Cell Lymphoblastic Leukemia-Lymphoma 4 | 49
acute lymphocytic leukemia 4 | 33
glioblastoma 4 | 5,792
malignant mesothelioma 4 | 3,232
pancreatic cancer 4 | 2,398
pituitary cancer 4 | 1,972
primitive neuroectodermal tumor 4 | 3,035
Lymphoma 3 | 81
Melanoma 3 | 711
Rheumatoid arthritis 3 | 1,191
adult high grade glioma 3 | 3,801
atypical teratoid / rhabdoid tumor 3 | 5,112
breast carcinoma 3 | 1,638
cutaneous lupus erythematosus 3 | 1,057
diabetes mellitus 3 | 1,728
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
medulloblastoma, large-cell 3 | 6,241
ulcerative colitis 3 | 1,819
Actinic keratosis 2 | 21
Adenocarcinoma in situ 2 | 15
Adenoma 2 | 167
Anogenital venereal wart 2 | 14
Arthritis, Rheumatoid 2 | 174
Astrocytoma, Pilocytic 2 | 3,081
Barrett's esophagus 2 | 182
Biliary tract cancer 2 | 19
Bipolar Disorder 2 | 666
CMM1 2 | 5
Cervicitis 2 | 6
Cervix uteri carcinoma in situ 2 | 16
DOID:2627 2 | 94
Diffuse large B-cell lymphoma 2 | 39
Dysplastic nevus syndrome 2 | 7
ENSP00000256078 2 | 30
Esophageal carcinoma 2 | 16
Glaucoma 2 | 239
Head and neck squamous cell carcinoma 2 | 11
Immune system cancer 2 | 140
Kidney Failure 2 | 111
Leukemia 2 | 104
Li-Fraumeni syndrome 2 | 13
Liver cancer 2 | 604
Major Depressive Disorder 2 | 301
Melanoma, Cutaneous Malignant, Susceptibility To, 2 2 | 2
Melanoma-Astrocytoma Syndrome 2 | 2
Melanoma-Pancreatic Cancer Syndrome 2 | 2
Mouth Neoplasms 2 | 55
Myeloma, Multiple 2 | 6
Papilloma 2 | 44
Precursor B-Cell Lymphoblastic Leukemia-Lymphoma 2 | 12
Primary cutaneous T-cell lymphoma 2 | 29
Rheumatic fever 2 | 19
Sezary's disease 2 | 15
Skin cancer 2 | 469
Stomach cancer 2 | 30
Systemic lupus erythematosus 2 | 194
Upper respiratory tract disease 2 | 15
Urinary system cancer 2 | 4
Vascular disease 2 | 319
Wolf-Hirschhorn syndrome 2 | 32
acute T cell leukemia 2 | 17
ependymoma 2 | 4,679
familial melanoma 2 | 10
group 3 medulloblastoma 2 | 4,104
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
invasive ductal carcinoma 2 | 2,951
lung carcinoma 2 | 2,843
non-small cell lung cancer 2 | 2,890
pancreatic ductal carcinoma 2 | 11
primary Sjogren syndrome 2 | 735
psoriasis 2 | 6,694
skin melanoma 2 | 14
Acute Promyelocytic Leukemia 1 | 40
Adenocarcinoma 1 | 122
Carcinoma, Non-Small-Cell Lung 1 | 107
Carcinoma, Squamous Cell 1 | 110
Deglutition Disorders 1 | 132
Drooling 1 | 27
Erythema 1 | 58
Flushing 1 | 60
Glioma 1 | 74
Hodgkin's lymphoma 1 | 15
Leukemia, Promyelocytic, Acute 1 | 36
Lymphoma, T-Cell, Cutaneous 1 | 22
Malignant Squamous Cell Neoplasm 1 | 17
Nephrotic Syndrome 1 | 78
Peripheral Neuropathy 1 | 134
Sarcoma 1 | 62
Sezary Syndrome 1 | 27
Sialorrhea 1 | 28

Tissue

Blood and immune system 7 | 16,909
Digestive Tract 7 | 17,369
Endocrine System 7 | 18,159
Female tissues 7 | 17,400
Liver and Pancreas 7 | 16,750
Respiratory system 7 | 16,393
Skin and soft tissues 7 | 17,230
Urinary Tract 7 | 16,678
Male tissues 6 | 17,142
Nervous System 6 | 16,725
Cardiovascular System 5 | 15,192

Target Family

Transcription Factor 4 | 1,400
Enzyme 1 | 4,145
Kinase 1 | 634
Non-IDG 1 | 12,091
Transporter 1 | 473

GWAS Trait

Acute lymphoblastic leukemia (... 8 | 8
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
AT-rich interactive domain-containing protein 5B ARID5B Tbio Transcription Factor -1.71561 54.6 97
CCAAT/enhancer-binding protein epsilon CEBPE Tbio Transcription Factor -1.71776 57.4 246
DNA-binding protein Ikaros IKZF1 Tbio Transcription Factor -2.66732 483.6 400
Cyclin-dependent kinase inhibitor 2A CDKN2A Tbio Enzyme -3.72848 9058.6 1063
Large neutral amino acids transporter small subunit 2 SLC7A8 Tbio Transporter -1.20076 18.8 126
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha PIP4K2A Tbio Kinase -1.77895 57.4 244
Trans-acting T-cell-specific transcription factor GATA-3 GATA3 Tbio Transcription Factor -3.20678 1568.2 636
Tumor suppressor ARF CDKN2A Tbio Non-IDG -3.72848 9058.6 1063