Development Level

Tbio 2 | 10,625

IMPC Term

abnormal retinal pigmentation 1 | 61

Disease

Osteoarthritis 2 | 96
Acquired metabolic disease 1 | 267
Anemia 1 | 252
Brain infarction 1 | 17
Cerebrovascular disease 1 | 231
Cleidocranial dysplasia 1 | 10
Congenital Thrombotic Thrombocytopenic Purpura 1 | 1
Degenerative disc disease 1 | 28
Degenerative polyarthritis 1 | 93
Diarrhea 1 | 155
Disseminated intravascular coagulation 1 | 32
Hypersensitivity reaction type II disease 1 | 235
Hypertension 1 | 287
Immune thrombocytopenic purpura 1 | 2
Kidney disease 1 | 396
Osteoporosis 1 | 257
Purpura 1 | 17
Purpura, Thrombotic Thrombocytopenic 1 | 4
Thrombocytopenia 1 | 105
Thrombotic Microangiopathies 1 | 2
Thrombotic thrombocytopenic purpura 1 | 14
Tooth agenesis 1 | 36
Von Willebrand's disease 1 | 19
Weill-Marchesani syndrome 1 | 14
intraductal papillary-mucinous neoplasm (IPMN) 1 | 3,289
osteosarcoma 1 | 7,933
sonic hedgehog group medulloblastoma 1 | 1,482
tuberculosis 1 | 1,557

Tissue

Blood and immune system 2 | 17,995
Cardiovascular System 2 | 17,958
Digestive Tract 2 | 18,473
Endocrine System 2 | 18,512
Female tissues 2 | 18,647
Liver and Pancreas 2 | 18,136
Male tissues 2 | 17,969
Nervous System 2 | 18,561
Respiratory system 2 | 17,484
Skin and soft tissues 2 | 18,115
Urinary Tract 2 | 18,444

Target Family

Enzyme 1 | 4,146
Non-IDG 1 | 11,971

GWAS Trait

ADAMTS13 activity 2 | 2
Obesity-related traits 380 | 380
Schizophrenia 334 | 334
Height 250 | 250
Post bronchodilator FEV1/FVC r... 192 | 192
Body mass index 180 | 180
IgG glycosylation 162 | 162
Inflammatory bowel disease 117 | 117
Post bronchodilator FEV1 112 | 112
Crohn's disease 110 | 110
Blood metabolite levels 103 | 103
Type 2 diabetes 94 | 94
3-hydroxy-1-methylpropylmercap... 93 | 93
3-hydroxypropylmercapturic aci... 92 | 92
Ulcerative colitis 89 | 89
Platelet count 79 | 79
Systemic lupus erythematosus 78 | 78
HDL cholesterol 76 | 76
Rheumatoid arthritis 74 | 74
Cholesterol, total 73 | 73
Menarche (age at onset) 73 | 73
Diisocyanate-induced asthma 72 | 72
Multiple sclerosis 68 | 68
LDL cholesterol 67 | 67
QT interval 58 | 58
Metabolite levels 55 | 55
Atopic dermatitis 54 | 54
Bipolar disorder and schizophr... 54 | 54
Breast cancer 54 | 54
Prostate cancer 54 | 54
Triglycerides 53 | 53
Bipolar disorder 52 | 52
HIV-1 control 50 | 50
Post bronchodilator FEV1/FVC r... 50 | 50
HIV-1 viral setpoint 49 | 49
Cognitive performance 48 | 48
Amyotrophic lateral sclerosis ... 46 | 46
Bone mineral density 46 | 46
Clozapine-induced agranulocyto... 46 | 46
Attention deficit hyperactivit... 44 | 44
Blood pressure 44 | 44
Coronary heart disease 43 | 43
Glomerular filtration rate (cr... 43 | 43
Parkinson's disease 43 | 43
Type 1 diabetes 42 | 42
PR interval in Tripanosoma cru... 40 | 40
Post bronchodilator FEV1 in CO... 39 | 39
Alzheimer's disease (cognitive... 38 | 38
Educational attainment 38 | 38
Pulmonary function 38 | 38
Diffuse large B cell lymphoma 37 | 37
Inflammatory skin disease 37 | 37
Beta-2 microglubulin plasma le... 36 | 36
Glucose homeostasis traits 36 | 36
Urate levels 36 | 36
Blood metabolite ratios 35 | 35
Psoriasis 35 | 35
Autism spectrum disorder, atte... 34 | 34
Migraine 33 | 33
Coronary artery disease 32 | 32
Metabolic traits 32 | 32
Waist-to-hip ratio adjusted fo... 32 | 32
Cognitive function 31 | 31
Colorectal cancer 31 | 31
Amyotrophic lateral sclerosis 30 | 30
Myopia (pathological) 30 | 30
Obesity 30 | 30
Response to amphetamines 30 | 30
Systolic blood pressure 30 | 30
Alzheimer's disease (late onse... 29 | 29
Celiac disease 29 | 29
Phospholipid levels (plasma) 29 | 29
Red blood cell traits 29 | 29
Advanced age-related macular d... 28 | 28
Dental caries 28 | 28
Fibrinogen levels 28 | 28
Parental extreme longevity (95... 28 | 28
Pulmonary function (interactio... 28 | 28
Asthma 27 | 27
Cognitive decline rate in late... 27 | 27
Glomerular filtration rate in ... 27 | 27
Longevity 27 | 27
Mean platelet volume 27 | 27
Chronic kidney disease 26 | 26
Diabetic kidney disease 26 | 26
Diastolic blood pressure 26 | 26
Coronary artery calcification 25 | 25
Metabolic syndrome 25 | 25
Pancreatic cancer 25 | 25
Protein quantitative trait loc... 25 | 25
Hypertension 24 | 24
Migraine - clinic-based 24 | 24
Parental longevity (combined p... 24 | 24
Primary biliary cirrhosis 24 | 24
Thiazide-induced adverse metab... 24 | 24
Menopause (age at onset) 23 | 23
Response to antipsychotic trea... 23 | 23
Age-related macular degenerati... 22 | 22
Immune response to smallpox va... 22 | 22
Mild influenza (H1N1) infectio... 22 | 22
Sudden cardiac arrest 22 | 22

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