Development Level

Tbio 97 | 11,651
Tdark 32 | 6,593
Tchem 19 | 1,388
Tclin 2 | 612

Collection

RFA-RM-18-021 4 | 328
Kinase: IDG Consortium (Target... 2 | 125
GPCR: IDG Consortium (Targets) 1 | 126
Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, complete... 9 | 979
preweaning lethality, incomple... 6 | 499
abnormal behavior 3 | 298
decreased grip strength 3 | 116
abnormal bone structure 2 | 187
abnormal embryo size 2 | 220
abnormal testis morphology 2 | 43
decreased body weight 2 | 161
decreased bone mineral content 2 | 151
decreased bone mineral density 2 | 126
decreased circulating choleste... 2 | 93
decreased fasted circulating g... 2 | 65
decreased vertical activity 2 | 208
hyperactivity 2 | 148
increased body weight 2 | 25
increased circulating creatini... 2 | 38
increased erythrocyte cell num... 2 | 39
increased mean corpuscular hem... 2 | 96
limb grasping 2 | 41
small testis 2 | 58
abnormal bone mineralization 1 | 38
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal liver morphology 1 | 17
abnormal pelvic girdle bone mo... 1 | 12
abnormal retina morphology 1 | 71
abnormal rib morphology 1 | 10
abnormal seminal vesicle morph... 1 | 114
abnormal skin appearance 1 | 3
abnormal spinal cord morpholog... 1 | 9
abnormal vibrissa morphology 1 | 25
abnormal vitreous body morphol... 1 | 10
cataract 1 | 92
decreased NK cell number 1 | 2
decreased T cell number 1 | 15
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased brain size 1 | 4
decreased caudal vertebrae num... 1 | 53
decreased circulating alkaline... 1 | 46
decreased circulating calcium ... 1 | 36
decreased circulating creatine... 1 | 4
decreased circulating creatini... 1 | 39
decreased circulating glucose ... 1 | 126
decreased circulating iron lev... 1 | 32
decreased circulating magnesiu... 1 | 13
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased mature B cell number 1 | 7
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
decreased threshold for audito... 1 | 26
decreased total body fat amoun... 1 | 207
edema 1 | 59
enlarged heart 1 | 210
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased basophil cell number 1 | 7
increased body length 1 | 32
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating phosphat... 1 | 26
increased circulating triglyce... 1 | 42
increased eosinophil cell numb... 1 | 11
increased grip strength 1 | 41
increased heart rate 1 | 23
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 36
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
increased prepulse inhibition 1 | 32
increased startle reflex 1 | 112
long tibia 1 | 25
narrow eye opening 1 | 12
pallor 1 | 34
persistence of hyaloid vascula... 1 | 33
shortened RR interval 1 | 17
small adrenal glands 1 | 16
small heart 1 | 10
small liver 1 | 8
small lung 1 | 5
small spleen 1 | 19
small stomach 1 | 3
small thymus 1 | 16

Disease

Carcinoma 111 | 11,493
ovarian cancer 71 | 8,520
glioblastoma 64 | 5,792
osteosarcoma 62 | 7,950
ependymoma 61 | 4,679
medulloblastoma, large-cell 59 | 6,241
psoriasis 59 | 6,694
adult high grade glioma 54 | 3,801
atypical teratoid / rhabdoid tumor 54 | 5,112
lung cancer 51 | 4,740
Kidney cancer 47 | 2,613
Breast cancer 44 | 3,578
lung carcinoma 44 | 2,843
Astrocytoma, Pilocytic 41 | 3,081
group 3 medulloblastoma 41 | 4,104
oligodendroglioma 40 | 2,850
astrocytic glioma 39 | 2,597
non-small cell lung cancer 38 | 2,890
intraductal papillary-mucinous neoplasm (IPMN) 37 | 3,291
primitive neuroectodermal tumor 34 | 3,035
interstitial cystitis 33 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 32 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 31 | 2,955
pituitary cancer 30 | 1,972
malignant mesothelioma 28 | 3,232
pancreatic cancer 27 | 2,398
invasive ductal carcinoma 25 | 2,951
Cancer 24 | 2,499
subependymal giant cell astrocytoma 24 | 2,287
Pick disease 22 | 1,894
lung adenocarcinoma 22 | 2,716
ulcerative colitis 22 | 1,819
Liver cancer 21 | 604
Schizophrenia 21 | 1,160
group 4 medulloblastoma 19 | 1,855
ductal carcinoma in situ 18 | 1,745
breast carcinoma 17 | 1,638
tuberculosis 17 | 2,010
cystic fibrosis 16 | 1,696
Bipolar Disorder 15 | 666
Melanoma 15 | 711
Rheumatoid arthritis 15 | 1,191
colon cancer 15 | 1,478
adrenocortical carcinoma 14 | 1,428
pancreatic ductal adenocarcinoma liver metastasis 14 | 1,962
Skin cancer 13 | 469
active ulcerative colitis 12 | 764
nasopharyngeal carcinoma 12 | 1,058
Autosomal recessive predisposition 11 | 1,442
Epilepsy 11 | 792
Osteoporosis 11 | 363
cutaneous lupus erythematosus 11 | 1,057
diabetes mellitus 11 | 1,728
spina bifida 11 | 1,074
Acquired metabolic disease 10 | 336
Alzheimer's disease 10 | 658
active Crohn's disease 10 | 922
gastric carcinoma 10 | 807
Endometriosis 9 | 540
Intellectual disability 9 | 1,016
Mental Depression 9 | 333
aldosterone-producing adenoma 9 | 665
astrocytoma 9 | 1,146
primary pancreatic ductal adenocarcinoma 9 | 1,109
Atopic dermatitis 8 | 952
Liver Cirrhosis, Experimental 8 | 769
Major Depressive Disorder 8 | 301
Obesity 8 | 678
Prostatic Neoplasms 8 | 495
Unipolar Depression 8 | 250
acute quadriplegic myopathy 8 | 1,158
esophageal adenocarcinoma 8 | 737
Amyotrophic lateral sclerosis 7 | 451
Autistic Disorder 7 | 364
Multiple myeloma 7 | 1,332
sonic hedgehog group medulloblastoma 7 | 467
Alcoholic Intoxication, Chronic 6 | 289
Attention deficit hyperactivity disorder 6 | 278
Celiac disease 6 | 116
Depressive disorder 6 | 409
Down syndrome 6 | 499
Dull intelligence 6 | 645
Endometrial cancer 6 | 311
Low intelligence 6 | 645
Mental Retardation 6 | 645
Mental deficiency 6 | 645
Poor school performance 6 | 645
Seizures 6 | 596
Type 2 diabetes mellitus 6 | 272
juvenile dermatomyositis 6 | 1,187
medulloblastoma 6 | 720
non primary Sjogren syndrome sicca 6 | 891
Atrial Fibrillation 5 | 124
Crohn's disease 5 | 321
Muscle hypotonia 5 | 571
dermatomyositis 5 | 966
nephrosclerosis 5 | 333
pediatric high grade glioma 5 | 1,064
substance-related disorder 5 | 162
tuberculosis and treatment for 6 months 5 | 409

Tissue

Endocrine System 140 | 18,159
Female tissues 138 | 17,400
Skin and soft tissues 136 | 17,230
Digestive Tract 135 | 17,369
Urinary Tract 134 | 16,678
Liver and Pancreas 133 | 16,750
Male tissues 133 | 17,142
Nervous System 133 | 16,725
Respiratory system 133 | 16,393
Blood and immune system 128 | 16,909
Cardiovascular System 121 | 15,192

Target Family

Non-IDG 80 | 12,091
Enzyme 34 | 4,145
Kinase 12 | 634
Transcription Factor 12 | 1,400
GPCR 4 | 408
Ion Channel 3 | 344
Epigenetic 2 | 242
oGPCR 2 | 421
Nuclear Receptor 1 | 48

GWAS Trait

3-hydroxypropylmercapturic aci... 150 | 150
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Epithelial membrane protein 2 EMP2 Tbio Non-IDG -2.30856 210.6 116
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 PLCB1 Tbio Enzyme -2.50444 332.8 190
Testis-expressed protein 26 TEX26 Tdark Non-IDG 0.49 0.27 5
Secretoglobin family 1D member 1 SCGB1D1 Tbio Non-IDG -2.15875 142.3 0
RNA binding protein fox-1 homolog 1 RBFOX1 Tbio Non-IDG -2.00815 99.2 207
Thyrotropin-releasing hormone-degrading ectoenzyme TRHDE Tbio Enzyme -1.62910 39.1 51
Synaptic vesicle glycoprotein 2C SV2C Tbio Non-IDG -1.38055 21.0 85
Cystatin-D CST5 Tbio Non-IDG -1.65364 41.5 81
Plexin-A4 PLXNA4 Tbio Non-IDG -1.43719 26.5 116
Gamma-soluble NSF attachment protein NAPG Tbio Non-IDG -1.66116 45.2 127