Development Level
Tbio | 10,942 | 11,445 | |
Tdark | 4,845 | 6,588 | |
Tchem | 1,567 | 1,598 | |
Tclin | 600 | 613 |
Collection
RFA-RM-18-021 | 312 | 328 | |
Kinase: IDG Consortium (Target... | 121 | 125 | |
GPCR: IDG Consortium (Targets) | 115 | 126 | |
Ion Channel: IDG Consortium (T... | 95 | 99 | |
Kinase: IDG Consortium (Comple... | 36 | 37 | |
GPCR: IDG Consortium (Complete... | 23 | 25 |
IMPC Phenotype
preweaning lethality, complete... | 966 | 979 | |
preweaning lethality, incomple... | 491 | 499 | |
abnormal behavior | 293 | 298 | |
embryonic lethality prior to t... | 275 | 278 | |
embryonic lethality prior to o... | 238 | 239 | |
abnormal embryo size | 215 | 220 | |
enlarged heart | 205 | 210 | |
decreased total body fat amoun... | 202 | 207 | |
decreased vertical activity | 199 | 208 | |
abnormal bone structure | 182 | 187 | |
increased lean body mass | 166 | 172 | |
abnormal heart morphology | 160 | 162 | |
decreased body weight | 158 | 161 | |
decreased bone mineral content | 148 | 151 | |
hyperactivity | 144 | 148 | |
decreased lean body mass | 133 | 135 | |
hypoactivity | 129 | 132 | |
increased total body fat amoun... | 129 | 134 | |
decreased bone mineral density | 124 | 126 | |
decreased circulating glucose ... | 123 | 126 | |
male infertility | 120 | 123 | |
increased circulating alkaline... | 118 | 122 | |
abnormal seminal vesicle morph... | 112 | 114 | |
decreased grip strength | 112 | 116 | |
increased startle reflex | 106 | 112 | |
embryonic growth retardation | 105 | 106 | |
increased bone mineral content | 104 | 108 | |
decreased body length | 99 | 101 | |
increased or absent threshold ... | 99 | 101 | |
short tibia | 96 | 97 | |
increased mean corpuscular hem... | 93 | 96 | |
increased mean corpuscular vol... | 92 | 92 | |
decreased circulating choleste... | 91 | 93 | |
cataract | 90 | 92 | |
prenatal lethality prior to he... | 85 | 87 | |
decreased lymphocyte cell numb... | 82 | 83 | |
decreased circulating serum al... | 81 | 82 | |
decreased prepulse inhibition | 81 | 82 | |
abnormal lens morphology | 79 | 81 | |
decreased circulating triglyce... | 79 | 79 | |
decreased mean corpuscular vol... | 78 | 79 | |
improved glucose tolerance | 77 | 79 | |
increased circulating HDL chol... | 77 | 80 | |
decreased startle reflex | 75 | 75 | |
increased fasted circulating g... | 75 | 76 | |
decreased circulating insulin ... | 74 | 76 | |
decreased leukocyte cell numbe... | 73 | 73 | |
impaired glucose tolerance | 72 | 75 | |
small superior vagus ganglion | 72 | 74 | |
increased bone mineral density | 71 | 72 | |
increased circulating sodium l... | 71 | 71 | |
abnormal retina morphology | 69 | 71 | |
abnormal sleep behavior | 69 | 70 | |
abnormal eye morphology | 68 | 68 | |
abnormal gait | 67 | 69 | |
decreased circulating HDL chol... | 67 | 68 | |
decreased hemoglobin content | 66 | 68 | |
abnormal kidney morphology | 65 | 65 | |
increased circulating choleste... | 65 | 66 | |
abnormal coat-hair pigmentatio... | 64 | 64 | |
abnormal behavioral response t... | 63 | 66 | |
decreased fasted circulating g... | 63 | 65 | |
increased monocyte cell number | 63 | 63 | |
decreased erythrocyte cell num... | 61 | 62 | |
increased heart weight | 58 | 62 | |
edema | 57 | 59 | |
female infertility | 57 | 60 | |
small testis | 56 | 58 | |
abnormal spleen morphology | 53 | 55 | |
thrombocytopenia | 53 | 56 | |
decreased caudal vertebrae num... | 52 | 53 | |
abnormal skin morphology | 50 | 50 | |
hydrometra | 50 | 53 | |
decreased blood urea nitrogen ... | 49 | 51 | |
decreased mean corpuscular hem... | 49 | 50 | |
decreased circulating total pr... | 48 | 49 | |
increased blood urea nitrogen ... | 47 | 48 | |
increased leukocyte cell numbe... | 47 | 47 | |
abnormal neural tube closure | 46 | 46 | |
decreased circulating alanine ... | 46 | 47 | |
increased hematocrit | 46 | 46 | |
increased neutrophil cell numb... | 46 | 46 | |
decreased circulating alkaline... | 44 | 46 | |
decreased hematocrit | 44 | 46 | |
increased hemoglobin content | 43 | 45 | |
increased mean platelet volume | 43 | 45 | |
increased circulating triglyce... | 42 | 42 | |
abnormal testis morphology | 41 | 43 | |
decreased neutrophil cell numb... | 41 | 42 | |
enlarged spleen | 41 | 41 | |
abnormal epididymis morphology | 40 | 42 | |
decreased red blood cell distr... | 40 | 41 | |
limb grasping | 40 | 41 | |
increased circulating chloride... | 39 | 41 | |
increased erythrocyte cell num... | 39 | 39 | |
decreased circulating LDL chol... | 38 | 38 | |
increased circulating creatini... | 38 | 38 | |
increased grip strength | 38 | 41 | |
abnormal bone mineralization | 37 | 38 | |
prolonged QT interval | 37 | 38 |
Disease
Tissue
Endocrine System | 17,486 | 18,159 | |
Female tissues | 16,992 | 17,400 | |
Digestive Tract | 16,988 | 17,369 | |
Skin and soft tissues | 16,855 | 17,230 | |
Male tissues | 16,745 | 17,142 | |
Blood and immune system | 16,559 | 16,909 | |
Liver and Pancreas | 16,450 | 16,750 | |
Nervous System | 16,429 | 16,725 | |
Urinary Tract | 16,392 | 16,678 | |
Respiratory system | 16,116 | 16,393 | |
Cardiovascular System | 14,998 | 15,192 |
Target Family
Non-IDG | 10,456 | 12,091 | |
Enzyme | 3,941 | 4,145 | |
Transcription Factor | 1,328 | 1,400 | |
Kinase | 620 | 634 | |
Transporter | 454 | 473 | |
GPCR | 374 | 408 | |
Ion Channel | 330 | 344 | |
Epigenetic | 235 | 242 | |
oGPCR | 132 | 421 | |
Nuclear Receptor | 47 | 48 | |
TF/Epigenetic | 37 | 38 |
GTEx Tissue
Small Intestine - Terminal Ile... | 17,954 | 17,954 | |
Testis | 18,518 | 18,518 | |
Prostate | 18,213 | 18,213 | |
Cells - EBV-transformed lympho... | 18,186 | 18,186 | |
Brain - Hypothalamus | 18,169 | 18,169 | |
Pituitary | 18,147 | 18,147 | |
Pancreas | 18,123 | 18,123 | |
Adipose - Subcutaneous | 18,110 | 18,110 | |
Breast - Mammary Tissue | 18,103 | 18,103 | |
Colon - Sigmoid | 18,089 | 18,089 | |
Skin - Not Sun Exposed (Suprap... | 18,081 | 18,081 | |
Esophagus - Mucosa | 18,076 | 18,076 | |
Adrenal Gland | 18,071 | 18,071 | |
Liver | 18,071 | 18,071 | |
Brain - Frontal Cortex (BA9) | 18,069 | 18,069 | |
Lung | 18,057 | 18,057 | |
Brain - Cortex | 18,039 | 18,039 | |
Brain - Nucleus accumbens (bas... | 18,024 | 18,024 | |
Thyroid | 18,024 | 18,024 | |
Esophagus - Muscularis | 18,017 | 18,017 | |
Brain - Cerebellar Hemisphere | 18,015 | 18,015 | |
Brain - Hippocampus | 18,011 | 18,011 | |
Nerve - Tibial | 18,007 | 18,007 | |
Brain - Amygdala | 18,006 | 18,006 | |
Heart - Left Ventricle | 18,006 | 18,006 | |
Minor Salivary Gland | 18,005 | 18,005 | |
Brain - Caudate (basal ganglia... | 18,001 | 18,001 | |
Esophagus - Gastroesophageal J... | 18,000 | 18,000 | |
Brain - Anterior cingulate cor... | 17,989 | 17,989 | |
Brain - Cerebellum | 17,983 | 17,983 | |
Brain - Substantia nigra | 17,981 | 17,981 | |
Brain - Spinal cord (cervical ... | 17,973 | 17,973 | |
Ovary | 17,971 | 17,971 | |
Skin - Sun Exposed (Lower leg) | 17,968 | 17,968 | |
Artery - Coronary | 17,949 | 17,949 | |
Adipose - Visceral (Omentum) | 17,937 | 17,937 | |
Artery - Aorta | 17,896 | 17,896 | |
Heart - Atrial Appendage | 17,896 | 17,896 | |
Stomach | 17,879 | 17,879 | |
Brain - Putamen (basal ganglia... | 17,863 | 17,863 | |
Vagina | 17,834 | 17,834 | |
Colon - Transverse | 17,825 | 17,825 | |
Muscle - Skeletal | 17,778 | 17,778 | |
Artery - Tibial | 17,631 | 17,631 | |
Uterus | 17,618 | 17,618 | |
Spleen | 17,614 | 17,614 | |
Cells - Transformed fibroblast... | 17,577 | 17,577 | |
Whole Blood | 17,439 | 17,439 | |
Kidney - Cortex | 17,329 | 17,329 |
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