Development Level

Tchem 6 | 1,598
Tbio 2 | 11,445
Tclin 2 | 613

IMPC Phenotype

abnormal vibrissa morphology 1 | 25
brachydactyly 1 | 19
embryonic lethality prior to t... 1 | 278
increased bone mineral content 1 | 108
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 9 | 11,493
lung carcinoma 6 | 2,843
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
lung cancer 5 | 4,740
malignant mesothelioma 5 | 3,232
psoriasis 5 | 6,694
Astrocytoma, Pilocytic 4 | 3,081
Autosomal recessive predisposition 4 | 1,442
Cancer 4 | 2,499
cystic fibrosis 4 | 1,696
ependymoma 4 | 4,679
medulloblastoma, large-cell 4 | 6,241
ovarian cancer 4 | 8,520
Angioedema 3 | 38
Bipolar Disorder 3 | 666
Factor XII deficiency 3 | 13
Hypertension 3 | 396
Pancreatitis 3 | 123
Partial thromboplastin time increased (finding) 3 | 11
Vascular disease 3 | 319
adult high grade glioma 3 | 3,801
atypical teratoid / rhabdoid tumor 3 | 5,112
diabetes mellitus 3 | 1,728
glioblastoma 3 | 5,792
group 3 medulloblastoma 3 | 4,104
invasive ductal carcinoma 3 | 2,951
lung adenocarcinoma 3 | 2,716
non-small cell lung cancer 3 | 2,890
pancreatic cancer 3 | 2,398
primary pancreatic ductal adenocarcinoma 3 | 1,109
subependymal giant cell astrocytoma 3 | 2,287
Animal Mammary Neoplasms 2 | 136
Arthritis 2 | 290
Arthropathy 2 | 43
Atopic dermatitis 2 | 952
C1 inhibitor deficiency 2 | 8
Coagulation time prolonged 2 | 4
Gingival Hyperplasia 2 | 34
Gingival Hypertrophy 2 | 34
Gingival Overgrowth 2 | 36
Hepatitis B 2 | 108
Mammary Neoplasms, Animal 2 | 136
Mammary Neoplasms, Experimental 2 | 154
Thrombophilia 2 | 38
Thrombosis 2 | 46
adrenocortical carcinoma 2 | 1,428
group 4 medulloblastoma 2 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
osteosarcoma 2 | 7,950
periodontitis 2 | 293
Abdominal pain, episodic 1 | 9
Alcoholism 1 | 45
Algoneurodystrophy 1 | 4
Amyloidosis 1 | 67
Aortic Aneurysm, Abdominal 1 | 9
Atrophic scar 1 | 18
Autoimmune thyroiditis 1 | 27
Axenfeld-Rieger syndrome 1 | 14
Cataplexy 1 | 11
Cell Transformation, Neoplastic 1 | 97
Cholangitis 1 | 32
Choledocholithiasis 1 | 11
Chronic Obstructive Airway Disease 1 | 37
Complement deficiency 1 | 14
Complement deficiency disease 1 | 6
Decreased size of teeth 1 | 62
Decreased width of tooth 1 | 59
Deep Vein Thrombosis 1 | 8
Diabetes Mellitus, Insulin-Dependent 1 | 48
Diabetes Mellitus, Type 1 1 | 43
Diabetic retinopathy 1 | 56
Furrowed palms and soles 1 | 4
Gastrointestinal Hemorrhage 1 | 52
Generalized osteoporosis with pathologic fractures 1 | 6
Hemarthrosis 1 | 12
Hemorrhage 1 | 19
Hepatitis 1 | 67
Hepatitis A 1 | 11
Joint laxity 1 | 54
Liver Neoplasms, Experimental 1 | 59
Microdontia (disorder) 1 | 59
Neoplastic Cell Transformation 1 | 89
Nephritis 1 | 51
Pleurisy 1 | 19
Poor wound healing 1 | 8
Prevention of Thromboembolism with Chronic Atrial Fibrillation 1 | 5
Prevention of deep vein thrombosis 1 | 7
Progeria 1 | 25
Pulmonary Disease, Chronic Obstructive 1 | 31
RETINITIS PIGMENTOSA 43 1 | 4
Recurrent bronchitis 1 | 23
Substance abuse 1 | 59
Thiopurine S-methyltransferase deficiency 1 | 6
Thromboembolism 1 | 15
Thyroiditis 1 | 29
Type 1 diabetes mellitus 1 | 109
Venezuelan equine encephalitis 1 | 7
Von Willebrand's disease 1 | 19
intermittent abdominal pain 1 | 9

Tissue

Liver and Pancreas 10 | 16,750
Urinary Tract 10 | 16,678
Blood and immune system 9 | 16,909
Digestive Tract 9 | 17,369
Endocrine System 9 | 18,159
Female tissues 9 | 17,400
Nervous System 9 | 16,725
Skin and soft tissues 9 | 17,230
Male tissues 8 | 17,142
Respiratory system 8 | 16,393
Cardiovascular System 7 | 15,192

Target Family

Enzyme 8 | 4,145
Non-IDG 2 | 12,091

GO Process

zymogen activation 10 | 10
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Trypsin-3 PRSS3 Tchem Enzyme -2.50102 549.4 308
Pro-cathepsin H CTSH Tchem Enzyme -2.36930 222.0 253
Neurotrypsin PRSS12 Tbio Non-IDG -1.46986 30.6 77
Matrix metalloproteinase-14 MMP14 Tchem Enzyme -3.01152 1087.9 840
Plasma kallikrein KLKB1 Tclin Enzyme -2.89608 720.1 284
Coagulation factor IX F9 Tchem Enzyme -3.54783 3496.6 414
Complement C1r subcomponent C1R Tclin Non-IDG -2.52739 315.0 221
Coagulation factor XII F12 Tchem Enzyme -2.86349 729.4 400
Furin FURIN Tchem Enzyme -3.10213 1183.5 260
Glutathione hydrolase 1 proenzyme GGT1 Tbio Enzyme -3.13033 1793.6 313