Development Level

Tbio 47 | 11,445
Tchem 31 | 1,598
Tclin 6 | 613
Tdark 2 | 6,588

IMPC Phenotype

abnormal retina morphology 2 | 71
abnormal retinal vasculature m... 2 | 27
decreased body weight 2 | 161
decreased prepulse inhibition 2 | 82
increased mean corpuscular vol... 2 | 92
increased or absent threshold ... 2 | 101
increased startle reflex 2 | 112
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal hair growth 1 | 10
abnormal heart left ventricle ... 1 | 16
abnormal retinal blood vessel ... 1 | 26
abnormal sleep behavior 1 | 70
abnormal vibrissa morphology 1 | 25
decreased circulating HDL chol... 1 | 68
decreased circulating creatini... 1 | 39
decreased circulating glucose ... 1 | 126
decreased circulating triglyce... 1 | 79
decreased mean corpuscular vol... 1 | 79
decreased neutrophil cell numb... 1 | 42
hyperactivity 1 | 148
increased IgA level 1 | 1
increased bone mineral density 1 | 72
increased cardiac muscle contr... 1 | 8
increased caudal vertebrae num... 1 | 7
increased circulating creatini... 1 | 38
increased circulating sodium l... 1 | 71
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 96
increased mean corpuscular hem... 1 | 36
increased total retina thickne... 1 | 4
preweaning lethality, complete... 1 | 979
thin ventricular wall 1 | 24
thrombocytopenia 1 | 56

Disease

Carcinoma 57 | 11,493
ovarian cancer 42 | 8,520
psoriasis 42 | 6,694
intraductal papillary-mucinous neoplasm (IPMN) 34 | 3,291
Cancer 31 | 2,499
medulloblastoma, large-cell 29 | 6,241
osteosarcoma 29 | 7,950
intraductal papillary-mucinous adenoma (IPMA) 28 | 2,955
lung carcinoma 26 | 2,843
pancreatic ductal adenocarcinoma liver metastasis 26 | 1,962
lung cancer 25 | 4,740
glioblastoma 22 | 5,792
intraductal papillary-mucinous carcinoma (IPMC) 20 | 2,989
malignant mesothelioma 20 | 3,232
atypical teratoid / rhabdoid tumor 19 | 5,112
ependymoma 19 | 4,679
lung adenocarcinoma 18 | 2,716
tuberculosis 18 | 2,010
interstitial cystitis 17 | 2,312
invasive ductal carcinoma 17 | 2,951
Prostatic Neoplasms 16 | 495
adult high grade glioma 16 | 3,801
diabetes mellitus 16 | 1,728
pancreatic cancer 16 | 2,398
ulcerative colitis 16 | 1,819
group 3 medulloblastoma 15 | 4,104
Breast cancer 14 | 3,578
Chemical and Drug Induced Liver Injury 14 | 195
cystic fibrosis 14 | 1,696
non-small cell lung cancer 14 | 2,890
Schizophrenia 13 | 1,160
adrenocortical carcinoma 13 | 1,428
esophageal adenocarcinoma 13 | 737
ductal carcinoma in situ 12 | 1,745
pituitary cancer 11 | 1,972
primitive neuroectodermal tumor 11 | 3,035
Astrocytoma, Pilocytic 10 | 3,081
Liver disease 10 | 237
astrocytic glioma 10 | 2,597
oligodendroglioma 10 | 2,850
Breast Neoplasms 9 | 445
Drug-Related Side Effects and Adverse Reactions 9 | 62
Hypertension 9 | 396
Liver Cirrhosis, Experimental 9 | 769
Mammary Neoplasms 9 | 425
Pick disease 9 | 1,894
breast carcinoma 9 | 1,638
colon cancer 9 | 1,478
cutaneous lupus erythematosus 9 | 1,057
subependymal giant cell astrocytoma 9 | 2,287
Adverse reaction to drug 8 | 61
Alcoholic Intoxication, Chronic 8 | 289
Autosomal recessive predisposition 8 | 1,442
Melanoma 8 | 711
Obesity 8 | 678
Acute kidney injury 7 | 70
Epilepsy 7 | 792
Lung Neoplasms 7 | 232
Precursor Cell Lymphoblastic Leukemia Lymphoma 7 | 43
Precursor Cell Lymphoblastic Leukemia-Lymphoma 7 | 49
acute quadriplegic myopathy 7 | 1,158
Bladder Neoplasm 6 | 112
Cholestasis 6 | 155
Contact Dermatitis 6 | 81
Depressive disorder 6 | 409
Dermatitis, Contact 6 | 71
Endometriosis 6 | 540
Hepatomegaly 6 | 285
Rheumatoid arthritis 6 | 1,191
Urinary Bladder Neoplasms 6 | 114
active Crohn's disease 6 | 922
aldosterone-producing adenoma 6 | 665
fibroadenoma 6 | 559
head and neck cancer and chronic obstructive pulmonary disease 6 | 239
mucosa-associated lymphoid tissue lymphoma 6 | 484
nephrosclerosis 6 | 333
spina bifida 6 | 1,074
Amphetamine-Related Disorders 5 | 74
Atopic dermatitis 5 | 952
Coronary artery disease 5 | 268
Hypertensive disease 5 | 292
Malaria 5 | 160
Parkinson Disease 5 | 64
active ulcerative colitis 5 | 764
chronic rhinosinusitis 5 | 512
group 4 medulloblastoma 5 | 1,855
non diabetic and post-ischemic heart failure 5 | 200
non primary Sjogren syndrome sicca 5 | 891
non-small cell lung carcinoma 5 | 317
pancreatic carcinoma 5 | 562
periodontitis 5 | 293
primary pancreatic ductal adenocarcinoma 5 | 1,109
Alzheimer's disease 4 | 658
Multiple myeloma 4 | 1,332
Vascular disease 4 | 319
Waldenstrons macroglobulinemia 4 | 765
gastric carcinoma 4 | 807
hepatocellular carcinoma 4 | 547
nasopharyngeal carcinoma 4 | 1,058
pediatric high grade glioma 4 | 1,064

Tissue

Digestive Tract 82 | 17,369
Liver and Pancreas 82 | 16,750
Female tissues 81 | 17,400
Endocrine System 80 | 18,159
Skin and soft tissues 80 | 17,230
Male tissues 79 | 17,142
Urinary Tract 79 | 16,678
Blood and immune system 77 | 16,909
Respiratory system 76 | 16,393
Nervous System 72 | 16,725
Cardiovascular System 65 | 15,192

Target Family

Enzyme 58 | 4,145
Non-IDG 20 | 12,091
Nuclear Receptor 4 | 48
Transcription Factor 4 | 1,400

GO Process

xenobiotic metabolic process 86 | 86
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cholesterol 24-hydroxylase CYP46A1 Tbio Enzyme -1.84856 68.6 197
Aryl hydrocarbon receptor repressor AHRR Tbio Transcription Factor -1.68768 52.8 77
Cytochrome P450 26A1 CYP26A1 Tchem Enzyme -2.44772 290.1 197
NADPH--cytochrome P450 reductase POR Tbio Enzyme -2.43541 216.2 257
Aflatoxin B1 aldehyde reductase member 2 AKR7A2 Tbio Enzyme -2.57327 369.6 197
Sulfotransferase 1A3 SULT1A3 Tbio Enzyme -2.23459 201.6 133
NAD(P)H dehydrogenase [quinone] 1 NQO1 Tchem Enzyme -3.12097 1326.4 550
Glycine N-acyltransferase GLYAT Tbio Enzyme -1.91086 76.4 110
UDP-glucuronosyltransferase 2B15 UGT2B15 Tbio Enzyme -1.79589 61.5 83
Prostaglandin G/H synthase 1 PTGS1 Tclin Enzyme -3.23035 1641.3 479