Development Level

Tbio 51 | 11,445
Tchem 14 | 1,598
Tclin 10 | 613
Tdark 4 | 6,588

IMPC Phenotype

preweaning lethality, complete... 7 | 979
decreased lean body mass 4 | 135
increased circulating choleste... 4 | 66
abnormal lens morphology 3 | 81
cataract 3 | 92
decreased body weight 3 | 161
decreased bone mineral content 3 | 151
increased circulating HDL chol... 3 | 80
mammalian phenotype 3 | 17
abnormal bone structure 2 | 187
abnormal eye morphology 2 | 68
abnormal humerus morphology 2 | 11
abnormal retina morphology 2 | 71
abnormal seminal vesicle morph... 2 | 114
abnormal snout morphology 2 | 23
decreased blood urea nitrogen ... 2 | 51
decreased bone mineral density 2 | 126
decreased circulating serum al... 2 | 82
decreased lymphocyte cell numb... 2 | 83
decreased neutrophil cell numb... 2 | 42
enlarged heart 2 | 210
impaired glucose tolerance 2 | 75
increased blood urea nitrogen ... 2 | 48
increased heart weight 2 | 62
increased neutrophil cell numb... 2 | 46
increased startle reflex 2 | 112
increased total body fat amoun... 2 | 134
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal craniofacial morpholo... 1 | 33
abnormal embryo size 1 | 220
abnormal femur morphology 1 | 14
abnormal head morphology 1 | 10
abnormal hindbrain morphology 1 | 10
abnormal locomotor activation 1 | 16
abnormal midbrain morphology 1 | 10
abnormal neural tube closure 1 | 46
abnormal optic disc morphology 1 | 10
abnormal pericardium morpholog... 1 | 26
abnormal placenta size 1 | 20
abnormal response to new envir... 1 | 10
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal startle reflex 1 | 15
abnormal tail movements 1 | 12
abnormal testis morphology 1 | 43
abnormal tooth morphology 1 | 24
cardiovascular system phenotyp... 1 | 36
corneal opacity 1 | 32
decreased IgE level 1 | 6
decreased body length 1 | 101
decreased cardiac muscle contr... 1 | 11
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alkaline... 1 | 46
decreased circulating aspartat... 1 | 34
decreased circulating choleste... 1 | 93
decreased circulating fructosa... 1 | 30
decreased circulating triglyce... 1 | 79
decreased eosinophil cell numb... 1 | 24
decreased grip strength 1 | 116
decreased heart rate 1 | 18
decreased heart weight 1 | 27
decreased lactate dehydrogenas... 1 | 16
decreased mean corpuscular hem... 1 | 31
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
decreased vertical activity 1 | 208
edema 1 | 59
embryonic growth retardation 1 | 106
enlarged lymph nodes 1 | 37
enlarged spleen 1 | 41
fused cornea and lens 1 | 5
hydrometra 1 | 53
hypoactivity 1 | 132
impaired pupillary reflex 1 | 26
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating calcium ... 1 | 34
increased circulating creatini... 1 | 38
increased circulating glucose ... 1 | 24
increased circulating total pr... 1 | 28
increased circulating triglyce... 1 | 42
increased hematocrit 1 | 46
increased lean body mass 1 | 172
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
iris synechia 1 | 3
limb grasping 1 | 41
narrow eye opening 1 | 12
pale yolk sac 1 | 25
persistence of hyaloid vascula... 1 | 33
prenatal lethality prior to he... 1 | 87
prolonged PQ interval 1 | 5
small heart 1 | 10
small superior vagus ganglion 1 | 74
thrombocytosis 1 | 27
trunk curl 1 | 16

Disease

Carcinoma 58 | 11,493
ovarian cancer 51 | 8,520
Cancer 49 | 2,499
glioblastoma 45 | 5,792
osteosarcoma 44 | 7,950
pancreatic cancer 39 | 2,398
Breast cancer 38 | 3,578
lung cancer 36 | 4,740
psoriasis 36 | 6,694
medulloblastoma, large-cell 34 | 6,241
non-small cell lung cancer 33 | 2,890
atypical teratoid / rhabdoid tumor 31 | 5,112
ependymoma 31 | 4,679
lung adenocarcinoma 31 | 2,716
interstitial cystitis 29 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 29 | 2,955
invasive ductal carcinoma 29 | 2,951
malignant mesothelioma 28 | 3,232
group 3 medulloblastoma 27 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 27 | 3,291
cystic fibrosis 26 | 1,696
lung carcinoma 26 | 2,843
Kidney cancer 25 | 2,613
Astrocytoma, Pilocytic 24 | 3,081
adult high grade glioma 24 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 22 | 2,989
ductal carcinoma in situ 21 | 1,745
oligodendroglioma 20 | 2,850
ulcerative colitis 20 | 1,819
Hypertensive disease 18 | 292
breast carcinoma 18 | 1,638
primary pancreatic ductal adenocarcinoma 17 | 1,109
primitive neuroectodermal tumor 17 | 3,035
subependymal giant cell astrocytoma 17 | 2,287
Schizophrenia 16 | 1,160
astrocytic glioma 16 | 2,597
pancreatic ductal adenocarcinoma liver metastasis 16 | 1,962
tuberculosis 16 | 2,010
Liver Cirrhosis, Experimental 15 | 769
diabetes mellitus 15 | 1,728
nasopharyngeal carcinoma 15 | 1,058
spina bifida 15 | 1,074
Breast Neoplasms 14 | 445
Duchenne muscular dystrophy 14 | 601
Mammary Neoplasms 14 | 425
colon cancer 14 | 1,478
cutaneous lupus erythematosus 14 | 1,057
Atopic dermatitis 13 | 952
esophageal adenocarcinoma 13 | 737
Coronary artery disease 12 | 268
Hypertension 12 | 396
active ulcerative colitis 12 | 764
Heart disease 11 | 306
Kidney disease 11 | 430
Orbital separation excessive 11 | 244
autosomal dominant Emery-Dreifuss muscular dystrophy 11 | 510
Cleft Palate 10 | 271
Increase in blood pressure 10 | 119
Lung Neoplasms 10 | 232
Prostatic Neoplasms 10 | 495
Pulmonary Fibrosis 10 | 106
active Crohn's disease 10 | 922
gastric carcinoma 10 | 807
juvenile dermatomyositis 10 | 1,187
Aortic Valve Insufficiency 9 | 40
Cardiomegaly 9 | 116
Liver Cirrhosis 9 | 181
Melanoma 9 | 711
Pick disease 9 | 1,894
Short stature 9 | 531
acute quadriplegic myopathy 9 | 1,158
adrenocortical carcinoma 9 | 1,428
fibroadenoma 9 | 559
group 4 medulloblastoma 9 | 1,855
pituitary cancer 9 | 1,972
Acquired scoliosis 8 | 281
Alzheimer's disease 8 | 658
Animal Mammary Neoplasms 8 | 136
Atherosclerosis 8 | 291
Autosomal recessive predisposition 8 | 1,442
Bipolar Disorder 8 | 666
Curvature of spine 8 | 282
Epilepsy 8 | 792
Exophthalmos 8 | 112
Hypoplastic mandible condyle 8 | 275
Mammary Neoplasms, Animal 8 | 136
Mammary Neoplasms, Experimental 8 | 154
Mandibular hypoplasia 8 | 275
Micrognathism 8 | 275
Polycystic ovary syndrome 8 | 360
Renal Cell Carcinoma 8 | 214
Seizures 8 | 596
Vascular disease 8 | 319
mucosa-associated lymphoid tissue lymphoma 8 | 484
non primary Sjogren syndrome sicca 8 | 891
pediatric high grade glioma 8 | 1,064
Depressive disorder 7 | 409
astrocytoma 7 | 1,146
nephrosclerosis 7 | 333
primary Sjogren syndrome 7 | 735

Tissue

Digestive Tract 77 | 17,369
Endocrine System 77 | 18,159
Female tissues 77 | 17,400
Blood and immune system 76 | 16,909
Liver and Pancreas 76 | 16,750
Respiratory system 76 | 16,393
Skin and soft tissues 76 | 17,230
Urinary Tract 75 | 16,678
Male tissues 74 | 17,142
Nervous System 74 | 16,725
Cardiovascular System 70 | 15,192

Target Family

Non-IDG 49 | 12,091
Kinase 13 | 634
Enzyme 6 | 4,145
Transcription Factor 5 | 1,400
GPCR 3 | 408
Nuclear Receptor 2 | 48
Transporter 1 | 473

GO Process

wound healing 79 | 79
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Endoglin ENG Tbio Non-IDG -3.10482 1235.9 1622
Aquaporin-1 AQP1 Tbio Non-IDG -3.08125 1107.4 374
Cerebral cavernous malformations 2 protein-like CCM2L Tdark Non-IDG -0.06695 1.24 54
Scavenger receptor class B member 1 SCARB1 Tchem Non-IDG -2.93920 915.7 378
Discoidin, CUB and LCCL domain-containing protein 2 DCBLD2 Tbio Non-IDG -1.08601 14.5 196
Coronin-1B CORO1B Tbio Non-IDG -1.09320 13.6 149
C-C motif chemokine 20 CCL20 Tbio Non-IDG -3.10283 1250.3 496
ETS domain-containing protein Elk-3 ELK3 Tbio Transcription Factor -0.17124 0.86 225
Fibronectin FN1 Tchem Non-IDG -3.09873 1208.8 1583
Alpha-(1,3)-fucosyltransferase 10 FUT10 Tdark Enzyme -0.25307 1.95 121