Development Level

Tbio 161 | 11,445
Tchem 15 | 1,598
Tclin 11 | 613
Tdark 11 | 6,588

Collection

RFA-RM-18-021 3 | 328
Ion Channel: IDG Consortium (T... 2 | 99
GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

enlarged heart 7 | 210
preweaning lethality, complete... 7 | 979
abnormal behavior 5 | 298
abnormal heart morphology 5 | 162
decreased vertical activity 5 | 208
preweaning lethality, incomple... 5 | 499
increased or absent threshold ... 4 | 101
abnormal retina morphology 3 | 71
decreased body weight 3 | 161
hyperactivity 3 | 148
hypoactivity 3 | 132
increased lean body mass 3 | 172
increased leukocyte cell numbe... 3 | 47
shortened RR interval 3 | 17
abnormal behavioral response t... 2 | 66
abnormal bone mineralization 2 | 38
abnormal bone structure 2 | 187
abnormal coat-hair pigmentatio... 2 | 64
abnormal embryo size 2 | 220
abnormal eye morphology 2 | 68
absent startle reflex 2 | 24
cardiovascular system phenotyp... 2 | 36
convulsive seizures 2 | 13
decreased circulating potassiu... 2 | 20
decreased circulating triglyce... 2 | 79
decreased heart rate variabili... 2 | 13
decreased hemoglobin content 2 | 68
decreased leukocyte cell numbe... 2 | 73
edema 2 | 59
impaired glucose tolerance 2 | 75
increased circulating glucose ... 2 | 24
increased circulating potassiu... 2 | 29
increased fasted circulating g... 2 | 76
increased heart rate 2 | 23
increased hematocrit 2 | 46
increased mean corpuscular hem... 2 | 96
increased mean corpuscular vol... 2 | 92
increased prepulse inhibition 2 | 32
increased total body fat amoun... 2 | 134
limb grasping 2 | 41
prolonged PR interval 2 | 15
short tibia 2 | 97
thrombocytopenia 2 | 56
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
abnormal heart left ventricle ... 1 | 16
abnormal liver morphology 1 | 17
abnormal locomotor activation 1 | 16
abnormal pericardium morpholog... 1 | 26
abnormal retinal blood vessel ... 1 | 26
abnormal sleep behavior 1 | 70
abnormal testis morphology 1 | 43
abnormal vibrissa morphology 1 | 25
abnormal whole-body plethysmog... 1 | 4
absent pinna reflex 1 | 23
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating amylase ... 1 | 28
decreased circulating calcium ... 1 | 36
decreased circulating chloride... 1 | 30
decreased circulating creatini... 1 | 39
decreased circulating free fat... 1 | 31
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased exploration in new e... 1 | 11
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased lean body mass 1 | 135
decreased mean platelet volume 1 | 25
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged spleen 1 | 41
enlarged uterus 1 | 11
hydroencephaly 1 | 14
impaired pupillary reflex 1 | 26
impaired righting response 1 | 26
increased blood urea nitrogen ... 1 | 48
increased blood uric acid leve... 1 | 5
increased body weight 1 | 25
increased bone mineral content 1 | 108
increased circulating alanine ... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating aspartat... 1 | 15
increased circulating sodium l... 1 | 71
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
increased startle reflex 1 | 112
increased vertical activity 1 | 24
persistence of hyaloid vascula... 1 | 33
prenatal lethality prior to he... 1 | 87
shortened PR interval 1 | 6
small adrenal glands 1 | 16
small testis 1 | 58
stereotypic behavior 1 | 3
trunk curl 1 | 16
vertebral fusion 1 | 23

Disease

Carcinoma 130 | 11,493
Autosomal recessive predisposition 73 | 1,442
Retinitis Pigmentosa 71 | 226
medulloblastoma, large-cell 62 | 6,241
psoriasis 60 | 6,694
Cataract 59 | 297
osteosarcoma 58 | 7,950
Nystagmus 57 | 317
ovarian cancer 56 | 8,520
Intellectual disability 52 | 1,016
Night Blindness 51 | 101
group 3 medulloblastoma 51 | 4,104
Blindness 50 | 88
Photodysphoria 50 | 121
Photophobia 50 | 121
glioblastoma 50 | 5,792
Electroretinogram abnormal 49 | 95
Lens Opacities 49 | 231
Difficulties with night vision 47 | 87
Low Vision 47 | 174
Retinal Degeneration 47 | 106
Visual Impairment 47 | 174
atypical teratoid / rhabdoid tumor 47 | 5,112
Abnormality of retinal pigmentation 46 | 111
Dull intelligence 46 | 645
Fundus dystrophy 46 | 83
Low intelligence 46 | 645
Mental Retardation 46 | 645
Mental deficiency 46 | 645
Poor school performance 46 | 645
Retinal pigment epithelial abnormality 46 | 111
ependymoma 46 | 4,679
Glaucoma 45 | 239
Sensorineural Hearing Loss (disorder) 42 | 284
Obesity 41 | 678
Kidney cancer 39 | 2,613
lung cancer 39 | 4,740
Cone dystrophy 38 | 71
adult high grade glioma 38 | 3,801
Blind Vision 37 | 111
Blindness, Legal 37 | 110
Myopia 37 | 176
Optic Atrophy 36 | 242
Breast cancer 35 | 3,578
Congenital hypoplasia of penis 35 | 176
Keratoconus 35 | 113
Reduced visual acuity 35 | 63
Hypogonadism 34 | 173
Anteverted nostril 32 | 191
Broad flat nasal bridge 31 | 236
Nasal bridge wide 31 | 236
oligodendroglioma 31 | 2,850
Abnormality of the retinal vasculature 30 | 59
Astrocytoma, Pilocytic 30 | 3,081
Conductive hearing loss 30 | 123
Ophthalmoplegia 30 | 106
primitive neuroectodermal tumor 30 | 3,035
Atypical scarring of skin 29 | 62
Congenital anomaly of testis 29 | 52
Hyperinsulinism 29 | 133
Night blindness, progressive 29 | 51
pituitary cancer 29 | 1,972
cone-rod dystrophy 28 | 59
lung carcinoma 28 | 2,843
Color vision defect 25 | 33
malignant mesothelioma 25 | 3,232
Abnormal color vision 23 | 31
Color vision defect, severe 23 | 31
astrocytic glioma 23 | 2,597
lung adenocarcinoma 23 | 2,716
Leber congenital amaurosis 22 | 69
invasive ductal carcinoma 22 | 2,951
Epilepsy 21 | 792
subependymal giant cell astrocytoma 20 | 2,287
Schizophrenia 19 | 1,160
Cancer 18 | 2,499
Melanoma 18 | 711
Pick disease 18 | 1,894
non-small cell lung cancer 18 | 2,890
pancreatic cancer 18 | 2,398
adrenocortical carcinoma 17 | 1,428
interstitial cystitis 17 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 17 | 2,955
Seizures 16 | 596
Visual field constriction 16 | 36
diabetes mellitus 16 | 1,728
Hyperopia 15 | 70
Muscle hypotonia 15 | 571
Strabismus 15 | 270
group 4 medulloblastoma 15 | 1,855
intraductal papillary-mucinous neoplasm (IPMN) 15 | 3,291
tuberculosis 15 | 2,010
intraductal papillary-mucinous carcinoma (IPMC) 14 | 2,989
Cerebellar Ataxia 13 | 304
Cognitive delay 13 | 608
Congenital stationary night blindness 13 | 29
Global developmental delay 13 | 608
Mental and motor retardation 13 | 608
Skin cancer 13 | 469
cystic fibrosis 13 | 1,696

Tissue

Endocrine System 185 | 18,159
Digestive Tract 165 | 17,369
Skin and soft tissues 162 | 17,230
Nervous System 160 | 16,725
Female tissues 157 | 17,400
Male tissues 150 | 17,142
Urinary Tract 150 | 16,678
Blood and immune system 149 | 16,909
Liver and Pancreas 146 | 16,750
Respiratory system 132 | 16,393
Cardiovascular System 114 | 15,192

Target Family

Non-IDG 104 | 12,091
Enzyme 32 | 4,145
Transcription Factor 21 | 1,400
GPCR 14 | 408
Ion Channel 13 | 344
Kinase 6 | 634
Transporter 5 | 473
Nuclear Receptor 3 | 48

GO Process

visual perception 198 | 198
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Oculomedin OCLM Tdark Non-IDG -1.09546 10.2 0
Neural retina-specific leucine zipper protein NRL Tbio Transcription Factor -2.46080 279.4 74
Gap junction delta-2 protein GJD2 Tbio Non-IDG -2.48933 326.9 192
Ceroid-lipofuscinosis neuronal protein 6 CLN6 Tbio Non-IDG -1.87357 0.00000 103
Beta-crystallin A3 CRYBA1 Tbio Non-IDG -1.45158 27.2 133
Gap junction alpha-3 protein GJA3 Tbio Non-IDG -2.14059 135.1 171
Bardet-Biedl syndrome 4 protein BBS4 Tbio Non-IDG -1.53435 31.5 200
Cone-rod homeobox protein CRX Tbio Transcription Factor -2.44826 272.0 185
Paired box protein Pax-2 PAX2 Tbio Transcription Factor -2.68609 492.0 349
Beta-crystallin B1 CRYBB1 Tbio Non-IDG -1.89050 77.2 109