Development Level

Tbio 317 | 11,445
Tchem 53 | 1,598
Tdark 20 | 6,588
Tclin 15 | 613

Collection

Kinase: IDG Consortium (Comple... 1 | 37
Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 34 | 979
preweaning lethality, incomple... 12 | 499
embryonic lethality prior to t... 8 | 278
embryonic lethality prior to o... 7 | 239
decreased total body fat amoun... 6 | 207
abnormal behavior 5 | 298
increased startle reflex 5 | 112
abnormal bone structure 4 | 187
abnormal embryo size 4 | 220
abnormal retina morphology 4 | 71
abnormal seminal vesicle morph... 3 | 114
decreased startle reflex 3 | 75
decreased vertical activity 3 | 208
increased bone mineral content 3 | 108
increased lymphocyte cell numb... 3 | 32
increased monocyte cell number 3 | 63
male infertility 3 | 123
abnormal craniofacial morpholo... 2 | 33
abnormal gait 2 | 69
abnormal heart morphology 2 | 162
abnormal neural tube closure 2 | 46
abnormal retinal blood vessel ... 2 | 26
abnormal retinal vasculature m... 2 | 27
decreased bone mineral content 2 | 151
decreased caudal vertebrae num... 2 | 53
decreased circulating alkaline... 2 | 46
decreased circulating choleste... 2 | 93
decreased circulating glucose ... 2 | 126
decreased grip strength 2 | 116
decreased lean body mass 2 | 135
decreased lymphocyte cell numb... 2 | 83
decreased red blood cell distr... 2 | 41
enlarged heart 2 | 210
enlarged lymph nodes 2 | 37
female infertility 2 | 60
hypoactivity 2 | 132
impaired glucose tolerance 2 | 75
increased blood urea nitrogen ... 2 | 48
increased body length 2 | 32
increased bone mineral density 2 | 72
increased circulating HDL chol... 2 | 80
increased circulating alkaline... 2 | 122
increased circulating chloride... 2 | 41
increased heart weight 2 | 62
increased hemoglobin content 2 | 45
increased lean body mass 2 | 172
increased leukocyte cell numbe... 2 | 47
increased mean corpuscular hem... 2 | 96
increased mean corpuscular vol... 2 | 92
increased neutrophil cell numb... 2 | 46
increased total body fat amoun... 2 | 134
abnormal cornea morphology 1 | 31
abnormal cranium morphology 1 | 36
abnormal eye morphology 1 | 68
abnormal femur morphology 1 | 14
abnormal heart left ventricle ... 1 | 16
abnormal iris morphology 1 | 13
abnormal lens morphology 1 | 81
abnormal lung morphology 1 | 26
abnormal midbrain development 1 | 20
abnormal placenta size 1 | 20
abnormal vitreous body morphol... 1 | 10
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
convulsive seizures 1 | 13
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased circulating HDL chol... 1 | 68
decreased circulating calcium ... 1 | 36
decreased circulating chloride... 1 | 30
decreased circulating free fat... 1 | 31
decreased circulating iron lev... 1 | 32
decreased circulating sodium l... 1 | 22
decreased fasted circulating g... 1 | 65
decreased heart left ventricle... 1 | 28
decreased hemoglobin content 1 | 68
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
decreased threshold for audito... 1 | 26
decreased total retina thickne... 1 | 17
edema 1 | 59
embryonic growth retardation 1 | 106
hemorrhage 1 | 23
hyperactivity 1 | 148
impaired righting response 1 | 26
increased blood uric acid leve... 1 | 5
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating potassiu... 1 | 29
increased eosinophil cell numb... 1 | 11
increased exploration in new e... 1 | 8
increased fasted circulating g... 1 | 76
increased large unstained cell... 1 | 5
increased red blood cell distr... 1 | 34
microphthalmia 1 | 26
short tibia 1 | 97
small superior vagus ganglion 1 | 74
small testis 1 | 58
tremors 1 | 39
vertebral fusion 1 | 23

Disease

Carcinoma 263 | 11,493
ovarian cancer 214 | 8,520
Cancer 195 | 2,499
psoriasis 190 | 6,694
osteosarcoma 174 | 7,950
lung cancer 153 | 4,740
glioblastoma 133 | 5,792
medulloblastoma, large-cell 129 | 6,241
atypical teratoid / rhabdoid tumor 100 | 5,112
dermatomyositis 98 | 966
diabetes mellitus 98 | 1,728
group 3 medulloblastoma 94 | 4,104
ependymoma 87 | 4,679
Breast cancer 85 | 3,578
Multiple myeloma 85 | 1,332
intraductal papillary-mucinous neoplasm (IPMN) 81 | 3,291
adult high grade glioma 78 | 3,801
Rheumatoid arthritis 75 | 1,191
Ankylosing spondylitis 72 | 140
Behcet's disease 71 | 89
Arthritis 70 | 290
malignant mesothelioma 69 | 3,232
Hypersensitivity reaction type II disease 66 | 253
Kidney cancer 66 | 2,613
intraductal papillary-mucinous carcinoma (IPMC) 65 | 2,989
tuberculosis 65 | 2,010
Acquired immunodeficiency syndrome 63 | 197
invasive ductal carcinoma 62 | 2,951
primitive neuroectodermal tumor 60 | 3,035
subependymal giant cell astrocytoma 58 | 2,287
Astrocytoma, Pilocytic 57 | 3,081
Herpes zoster 57 | 68
Juvenile rheumatoid arthritis 57 | 111
Stevens-Johnson syndrome 57 | 92
Uveitis 56 | 103
non-small cell lung cancer 56 | 2,890
oligodendroglioma 55 | 2,850
Human immunodeficiency virus infectious disease 53 | 138
lung carcinoma 52 | 2,843
juvenile dermatomyositis 51 | 1,187
Psoriatic arthritis 50 | 86
astrocytoma 49 | 1,146
lung adenocarcinoma 49 | 2,716
Waldenstrons macroglobulinemia 48 | 765
pancreatic cancer 47 | 2,398
intraductal papillary-mucinous adenoma (IPMA) 45 | 2,955
Multiple Sclerosis 44 | 540
Pick disease 42 | 1,894
astrocytic glioma 42 | 2,597
pancreatic ductal adenocarcinoma liver metastasis 42 | 1,962
Dermatitis 39 | 157
colon cancer 38 | 1,478
ulcerative colitis 38 | 1,819
acute quadriplegic myopathy 37 | 1,158
Behcet's syndrome 36 | 50
Schizophrenia 36 | 1,160
Synovitis 36 | 78
Takayasu's arteritis 36 | 53
cutaneous lupus erythematosus 36 | 1,057
primary Sjogren syndrome 36 | 735
Congenital adrenal hyperplasia 35 | 73
Kidney disease 35 | 430
Nephritis 35 | 51
Retinal vasculitis 35 | 36
Spondyloarthropathy, Susceptibility To, 1 35 | 35
drug-induced hepatitis 35 | 44
interstitial cystitis 34 | 2,312
adrenocortical carcinoma 31 | 1,428
group 4 medulloblastoma 31 | 1,855
breast carcinoma 30 | 1,638
pediatric high grade glioma 30 | 1,064
cystic fibrosis 29 | 1,696
ductal carcinoma in situ 29 | 1,745
pituitary cancer 29 | 1,972
Autosomal recessive predisposition 28 | 1,442
Intellectual disability 28 | 1,016
Liver disease 28 | 237
primary pancreatic ductal adenocarcinoma 28 | 1,109
Anemia 27 | 365
acute myeloid leukemia 25 | 783
Skin disease 24 | 66
active Crohn's disease 24 | 922
nasopharyngeal carcinoma 24 | 1,058
Breast Neoplasms 23 | 445
Hepatitis B 23 | 108
Primary immunodeficiency disease 23 | 54
Atopic dermatitis 22 | 952
Dull intelligence 22 | 645
Low intelligence 22 | 645
Mammary Neoplasms 22 | 425
Mental Retardation 22 | 645
Mental deficiency 22 | 645
Poor school performance 22 | 645
Epilepsy 21 | 792
HIV Infections 21 | 102
Leprosy 21 | 73
esophageal adenocarcinoma 21 | 737
Birdshot chorioretinopathy 20 | 23
Hemochromatosis 20 | 54
non primary Sjogren syndrome sicca 19 | 891

Tissue

Blood and immune system 326 | 16,909
Digestive Tract 326 | 17,369
Endocrine System 326 | 18,159
Female tissues 326 | 17,400
Liver and Pancreas 326 | 16,750
Male tissues 326 | 17,142
Nervous System 325 | 16,725
Respiratory system 325 | 16,393
Skin and soft tissues 325 | 17,230
Urinary Tract 325 | 16,678
Cardiovascular System 319 | 15,192

Target Family

Non-IDG 287 | 12,091
Enzyme 56 | 4,145
Epigenetic 18 | 242
Kinase 18 | 634
Transcription Factor 17 | 1,400
GPCR 4 | 408
Transporter 3 | 473
TF/Epigenetic 2 | 38

GO Process

viral process 405 | 405
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Serine incorporator 5 SERINC5 Tbio Non-IDG -1.50535 34.0 11
HLA class I histocompatibility antigen, B-35 alpha chain HLA-B Tbio Non-IDG -1.88752 1613.5 0
F-box/LRR-repeat protein 2 FBXL2 Tbio Non-IDG -0.89339 8.63 129
Histone-arginine methyltransferase CARM1 CARM1 Tchem Epigenetic -2.04034 130.8 476
Cullin-7 CUL7 Tbio Non-IDG -1.49747 38.0 139
E3 ubiquitin-protein ligase RNF216 RNF216 Tbio Enzyme -1.27012 17.8 170
Uridine-cytidine kinase-like 1 UCKL1 Tdark Kinase -0.15970 2.21 110
Nucleoporin NDC1 NDC1 Tbio Non-IDG -0.66901 4.57 46
Nascent polypeptide-associated complex subunit alpha NACA Tbio Non-IDG -1.15827 23.3 50
BTB/POZ domain-containing protein KCTD5 KCTD5 Tbio Non-IDG -1.70628 50.2 52