Development Level

Tbio 308 | 11,178
Tchem 63 | 1,885
Tdark 19 | 6,569
Tclin 15 | 612

Collection

Kinase: IDG Consortium (Comple... 1 | 37
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 34 | 979
preweaning lethality, incomple... 12 | 499
embryonic lethality prior to t... 8 | 278
embryonic lethality prior to o... 7 | 239
decreased total body fat amoun... 6 | 207
abnormal behavior 5 | 298
increased startle reflex 5 | 112
abnormal bone structure 4 | 187
abnormal embryo size 4 | 220
abnormal retina morphology 4 | 71
abnormal seminal vesicle morph... 3 | 114
decreased startle reflex 3 | 75
decreased vertical activity 3 | 208
increased bone mineral content 3 | 108
increased lymphocyte cell numb... 3 | 32
increased monocyte cell number 3 | 63
male infertility 3 | 123
abnormal craniofacial morpholo... 2 | 33
abnormal gait 2 | 69
abnormal heart morphology 2 | 162
abnormal neural tube closure 2 | 46
abnormal retinal blood vessel ... 2 | 26
abnormal retinal vasculature m... 2 | 27
decreased bone mineral content 2 | 151
decreased caudal vertebrae num... 2 | 53
decreased circulating alkaline... 2 | 46
decreased circulating choleste... 2 | 93
decreased circulating glucose ... 2 | 126
decreased grip strength 2 | 116
decreased lean body mass 2 | 135
decreased lymphocyte cell numb... 2 | 83
decreased red blood cell distr... 2 | 41
enlarged heart 2 | 210
enlarged lymph nodes 2 | 37
female infertility 2 | 60
hypoactivity 2 | 132
impaired glucose tolerance 2 | 75
increased blood urea nitrogen ... 2 | 48
increased body length 2 | 32
increased bone mineral density 2 | 72
increased circulating HDL chol... 2 | 80
increased circulating alkaline... 2 | 122
increased circulating chloride... 2 | 41
increased heart weight 2 | 62
increased hemoglobin content 2 | 45
increased lean body mass 2 | 172
increased leukocyte cell numbe... 2 | 47
increased mean corpuscular hem... 2 | 96
increased mean corpuscular vol... 2 | 92
increased neutrophil cell numb... 2 | 46
increased total body fat amoun... 2 | 134
abnormal cornea morphology 1 | 31
abnormal cranium morphology 1 | 36
abnormal eye morphology 1 | 68
abnormal femur morphology 1 | 14
abnormal heart left ventricle ... 1 | 16
abnormal iris morphology 1 | 13
abnormal lens morphology 1 | 81
abnormal lung morphology 1 | 26
abnormal midbrain development 1 | 20
abnormal placenta size 1 | 20
abnormal vitreous body morphol... 1 | 10
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
convulsive seizures 1 | 13
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased circulating HDL chol... 1 | 68
decreased circulating calcium ... 1 | 36
decreased circulating chloride... 1 | 30
decreased circulating free fat... 1 | 31
decreased circulating iron lev... 1 | 32
decreased circulating sodium l... 1 | 22
decreased fasted circulating g... 1 | 65
decreased heart left ventricle... 1 | 28
decreased hemoglobin content 1 | 68
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
decreased threshold for audito... 1 | 26
decreased total retina thickne... 1 | 17
edema 1 | 59
embryonic growth retardation 1 | 106
hemorrhage 1 | 23
hyperactivity 1 | 148
impaired righting response 1 | 26
increased blood uric acid leve... 1 | 5
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating potassiu... 1 | 29
increased eosinophil cell numb... 1 | 11
increased exploration in new e... 1 | 8
increased fasted circulating g... 1 | 76
increased large unstained cell... 1 | 5
increased red blood cell distr... 1 | 34
microphthalmia 1 | 26
short tibia 1 | 97
small superior vagus ganglion 1 | 74
small testis 1 | 58
tremors 1 | 39
vertebral fusion 1 | 23

Disease

Carcinoma 257 | 11,192
ovarian cancer 199 | 8,297
Cancer 189 | 2,388
psoriasis 183 | 6,514
osteosarcoma 169 | 7,766
lung cancer 145 | 4,607
glioblastoma 125 | 5,635
medulloblastoma, large-cell 125 | 6,086
atypical teratoid / rhabdoid tumor 97 | 4,971
diabetes mellitus 95 | 1,683
dermatomyositis 92 | 941
group 3 medulloblastoma 91 | 4,002
ependymoma 84 | 4,559
Breast cancer 80 | 3,469
intraductal papillary-mucinous neoplasm (IPMN) 78 | 3,204
adult high grade glioma 76 | 3,701
Rheumatoid arthritis 74 | 1,156
Ankylosing spondylitis 71 | 134
Behcet's disease 71 | 87
Multiple myeloma 71 | 1,296
Arthritis 69 | 276
Hypersensitivity reaction type II disease 66 | 245
malignant mesothelioma 66 | 3,135
Kidney cancer 65 | 2,548
Acquired immunodeficiency syndrome 63 | 192
intraductal papillary-mucinous carcinoma (IPMC) 63 | 2,902
tuberculosis 63 | 1,963
invasive ductal carcinoma 59 | 2,867
primitive neuroectodermal tumor 59 | 2,957
Herpes zoster 57 | 68
Juvenile rheumatoid arthritis 57 | 110
Stevens-Johnson syndrome 57 | 92
Uveitis 56 | 102
subependymal giant cell astrocytoma 56 | 2,230
Astrocytoma, Pilocytic 55 | 3,006
non-small cell lung cancer 54 | 2,799
Human immunodeficiency virus infectious disease 53 | 136
oligodendroglioma 51 | 2,768
Psoriatic arthritis 50 | 84
juvenile dermatomyositis 49 | 1,147
lung carcinoma 49 | 2,755
lung adenocarcinoma 47 | 2,627
astrocytoma 46 | 1,113
Multiple Sclerosis 44 | 527
intraductal papillary-mucinous adenoma (IPMA) 44 | 2,872
pancreatic cancer 44 | 2,322
Pick disease 41 | 1,856
astrocytic glioma 41 | 2,530
Waldenstrons macroglobulinemia 40 | 742
Dermatitis 39 | 154
pancreatic ductal adenocarcinoma liver metastasis 38 | 1,911
colon cancer 37 | 1,428
ulcerative colitis 37 | 1,765
Behcet's syndrome 36 | 49
Schizophrenia 36 | 1,136
Takayasu's arteritis 36 | 53
acute quadriplegic myopathy 36 | 1,133
Congenital adrenal hyperplasia 35 | 71
Nephritis 35 | 51
Retinal vasculitis 35 | 36
Spondyloarthropathy, Susceptibility To, 1 35 | 35
Synovitis 35 | 75
drug-induced hepatitis 35 | 44
Kidney disease 34 | 411
cutaneous lupus erythematosus 34 | 1,016
primary Sjogren syndrome 32 | 710
adrenocortical carcinoma 31 | 1,385
group 4 medulloblastoma 31 | 1,806
interstitial cystitis 31 | 2,237
breast carcinoma 29 | 1,589
pediatric high grade glioma 29 | 1,035
pituitary cancer 29 | 1,915
Intellectual disability 28 | 998
Liver disease 28 | 227
cystic fibrosis 28 | 1,629
ductal carcinoma in situ 28 | 1,686
Autosomal recessive predisposition 27 | 1,407
primary pancreatic ductal adenocarcinoma 27 | 1,071
Anemia 26 | 353
acute myeloid leukemia 24 | 760
Hepatitis B 23 | 105
Primary immunodeficiency disease 23 | 54
Skin disease 23 | 64
nasopharyngeal carcinoma 23 | 1,024
Breast Neoplasms 22 | 423
Dull intelligence 22 | 634
Low intelligence 22 | 634
Mental Retardation 22 | 634
Mental deficiency 22 | 634
Poor school performance 22 | 634
active Crohn's disease 22 | 882
Atopic dermatitis 21 | 915
Epilepsy 21 | 775
Leprosy 21 | 72
Mammary Neoplasms 21 | 403
Birdshot chorioretinopathy 20 | 22
Hemochromatosis 20 | 52
Alzheimer's disease 18 | 640
Stomach Neoplasms 18 | 287
esophageal adenocarcinoma 18 | 696

Tissue

Blood and immune system 326 | 16,909
Digestive Tract 326 | 17,369
Endocrine System 326 | 18,159
Female tissues 326 | 17,400
Liver and Pancreas 326 | 16,750
Male tissues 326 | 17,142
Nervous System 325 | 16,725
Respiratory system 325 | 16,393
Skin and soft tissues 325 | 17,230
Urinary Tract 325 | 16,678
Cardiovascular System 319 | 15,192

Target Family

Non-IDG 287 | 12,091
Enzyme 56 | 4,145
Epigenetic 18 | 242
Kinase 18 | 634
Transcription Factor 17 | 1,400
GPCR 4 | 408
Transporter 3 | 473
TF/Epigenetic 2 | 38

GO Process

viral process 405 | 405
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
General transcription factor IIE subunit 1 GTF2E1 Tbio Non-IDG 0.16 0.68 153
MyoD family inhibitor domain-containing protein MDFIC Tbio Non-IDG -2.90969 749.0 122
ATP-dependent DNA helicase DDX11 DDX11 Tbio Enzyme -1.05592 30.0 163
Chromodomain-helicase-DNA-binding protein 6 CHD6 Tbio Epigenetic -1.01113 11.4 31
HLA class I histocompatibility antigen, B-67 alpha chain HLA-B Tbio Non-IDG -1.88752 1613.5 362
DNA damage-binding protein 1 DDB1 Tchem Non-IDG -2.34719 202.5 353
Cell surface glycoprotein CD200 receptor 1 CD200R1 Tbio Non-IDG -1.93142 83.6 476
Ras-related protein Rab-6A RAB6A Tbio Enzyme -2.09488 134.5 207
Transcription initiation factor TFIID subunit 1 TAF1 Tbio Kinase -2.64215 426.1 228
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like BNIP3L Tbio Non-IDG -2.20837 153.7 355