Development Level

Tbio 8 | 10,625

IMPC Phenotype

embryonic lethality prior to t... 1 | 187

Disease

group 3 medulloblastoma 4 | 2,254
malignant mesothelioma 3 | 3,163
osteosarcoma 3 | 7,933
ovarian cancer 3 | 8,491
Breast cancer 2 | 3,098
Intellectual disability 2 | 573
glioblastoma 2 | 5,572
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,289
lung cancer 2 | 4,473
medulloblastoma, large-cell 2 | 6,234
pediatric high grade glioma 2 | 2,712
Atopic dermatitis 1 | 944
Beaulieu-Boycott-Innes syndrome 1 | 1
Carcinoma 1 | 2,147
Developmental delay-microcephaly-facial dysmorphism syndrome, Hutterite type 1 | 1
HIV Infections 1 | 99
Kaposi's sarcoma 1 | 20
Kernicterus 1 | 12
Mental retardation, X-linked 12 1 | 1
Multiple myeloma 1 | 1,327
Peliosis Hepatis 1 | 4
Plasmodium vivax malaria 1 | 2
Rheumatoid Arthritis 1 | 1,170
Schizophrenia 1 | 503
Waldenstrons macroglobulinemia 1 | 764
West Nile encephalitis 1 | 8
aldosterone-producing adenoma 1 | 664
angiosarcoma 1 | 10
astrocytic glioma 1 | 2,241
astrocytoma 1 | 1,493
atypical teratoid/rhabdoid tumor 1 | 1,095
diabetes mellitus 1 | 1,663
hereditary spastic paraplegia 1 | 313
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 1 | 2,988
invasive ductal carcinoma 1 | 2,950
nasopharyngeal carcinoma 1 | 1,056
non-small cell lung cancer 1 | 2,798
pancreatic cancer 1 | 2,300
pancreatic ductal adenocarcinoma liver metastasis 1 | 1,795
pilocytic astrocytoma 1 | 3,086
posterior fossa group A ependymoma 1 | 1,511
posterior fossa group B ependymoma 1 | 1,530
primary pancreatic ductal adenocarcinoma 1 | 1,271
primitive neuroectodermal tumor 1 | 3,031
psoriasis 1 | 6,685
sonic hedgehog group medulloblastoma 1 | 1,482
ulcerative colitis 1 | 2,087

Tissue

Blood and immune system 8 | 17,994
Cardiovascular System 8 | 17,957
Digestive Tract 8 | 18,472
Endocrine System 8 | 18,511
Female tissues 8 | 18,646
Liver and Pancreas 8 | 18,135
Male tissues 8 | 17,968
Nervous System 8 | 18,560
Respiratory system 8 | 17,483
Skin and soft tissues 8 | 18,114
Urinary Tract 8 | 18,443

Target Family

Non-IDG 7 | 11,969
Enzyme 1 | 4,146

GO Process

viral mRNA export from host ce... 8 | 8
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 367 | 367
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
chemical synaptic transmission 238 | 238
MAPK cascade 237 | 237
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 199 | 199
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 180 | 180
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 175 | 175
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
protein folding 162 | 162
negative regulation of canonic... 161 | 161
response to lipopolysaccharide 161 | 161
T cell receptor signaling path... 160 | 160
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2-M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
type I interferon signaling pa... 130 | 130
endocytosis 129 | 129

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Spliceosome RNA helicase DDX39B DDX39B Tbio Enzyme -1.70644 57.0 123
THO complex subunit 2 THOC2 Tbio Non-IDG -1.88663 76.8 47
THO complex subunit 3 THOC3 Tbio Non-IDG -0.90305 10.4 90
THO complex subunit 6 homolog THOC6 Tbio Non-IDG -1.72319 50.1 112
THO complex subunit 1 THOC1 Tbio Non-IDG -1.29482 23.3 227
THO complex subunit 5 homolog THOC5 Tbio Non-IDG -1.10371 16.8 92
THO complex subunit 7 homolog THOC7 Tbio Non-IDG -0.34772 2.04 43
THO complex subunit 4 ALYREF Tbio Non-IDG -2.43751 263.2 0