Development Level

Tbio 11 | 11,445
Tchem 2 | 1,598

IMPC Phenotype

increased circulating triglyce... 1 | 42
increased prepulse inhibition 1 | 32
limb grasping 1 | 41
preweaning lethality, incomple... 1 | 499

Disease

osteosarcoma 9 | 7,950
ovarian cancer 7 | 8,520
psoriasis 7 | 6,694
Carcinoma 6 | 11,493
group 3 medulloblastoma 6 | 4,104
lung carcinoma 6 | 2,843
atypical teratoid / rhabdoid tumor 5 | 5,112
ependymoma 5 | 4,679
medulloblastoma, large-cell 5 | 6,241
non-small cell lung cancer 5 | 2,890
oligodendroglioma 5 | 2,850
pancreatic cancer 5 | 2,398
Pick disease 4 | 1,894
acute quadriplegic myopathy 4 | 1,158
adult high grade glioma 4 | 3,801
astrocytic glioma 4 | 2,597
cystic fibrosis 4 | 1,696
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
lung cancer 4 | 4,740
tuberculosis 4 | 2,010
Astrocytoma, Pilocytic 3 | 3,081
Atopic dermatitis 3 | 952
Breast cancer 3 | 3,578
adrenocortical carcinoma 3 | 1,428
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
glioblastoma 3 | 5,792
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
progressive supranuclear palsy 3 | 676
subependymal giant cell astrocytoma 3 | 2,287
Autosomal dominant cerebellar ataxia 2 | 33
Duchenne muscular dystrophy 2 | 601
Ichthyosis 2 | 56
Intellectual disability 2 | 1,016
Multiple myeloma 2 | 1,332
Neurodegenerative disease 2 | 414
active Crohn's disease 2 | 922
acute myeloid leukemia 2 | 783
aldosterone-producing adenoma 2 | 665
dermatomyositis 2 | 966
ductal carcinoma in situ 2 | 1,745
gastric cancer 2 | 459
invasive ductal carcinoma 2 | 2,951
juvenile dermatomyositis 2 | 1,187
lung adenocarcinoma 2 | 2,716
malignant mesothelioma 2 | 3,232
pancreatic carcinoma 2 | 562
pituitary cancer 2 | 1,972
primary Sjogren syndrome 2 | 735
primitive neuroectodermal tumor 2 | 3,035
Abnormal visual evoked potential 1 | 26
Acquired scoliosis 1 | 281
Adrenoleukodystrophy 1 | 29
Age related macular degeneration 1 | 72
Arrhythmogenic right ventricular cardiomyopathy 1 | 30
Autosomal recessive non-syndromic intellectual disability 1 | 7
Axenfeld-Rieger syndrome 1 | 14
Catecholaminergic polymorphic ventricular tachycardia 1 | 12
Centronuclear myopathy 1 | 27
Color vision defect 1 | 33
Curvature of spine 1 | 282
Decreased tendon reflex 1 | 122
Decreased to absent deep tendon reflexes 1 | 42
Difficulties with night vision 1 | 87
Dry skin 1 | 75
Dysarthria 1 | 192
Dysdiadochokinesis 1 | 25
Epilepsy 1 | 792
Ethylmalonic encephalopathy 1 | 12
Fatty liver disease 1 | 103
Fundus dystrophy 1 | 83
Heart failure 1 | 162
Hypohidrosis 1 | 34
Hypomyelinating leukodystrophy 6 1 | 26
Infertility, Male 1 | 46
Leukemia 1 | 104
Liver Cirrhosis, Experimental 1 | 769
Macular degeneration 1 | 65
Myopathy 1 | 185
Night Blindness 1 | 101
Open-angle glaucoma 1 | 27
Pectus excavatum 1 | 100
Peroxisomal disease 1 | 22
Polycystic ovary syndrome 1 | 360
Progressive cerebellar ataxia 1 | 13
Recurrent respiratory infections 1 | 141
Retinal Degeneration 1 | 106
Retinitis pigmentosa 25 1 | 9
Simpson-Golabi-Behmel syndrome 1 | 19
Spastic Quadriplegia 1 | 42
Spinocerebellar Ataxias 1 | 34
Tinea pedis 1 | 29
Urticaria 1 | 67
Xerosis 1 | 75
active ulcerative colitis 1 | 764
breast carcinoma 1 | 1,638
cystic fibrosis and chronic rhinosinusitis 1 | 214
head and neck cancer 1 | 271
hereditary spastic paraplegia 1 | 318

Tissue

Blood and immune system 13 | 16,909
Digestive Tract 13 | 17,369
Endocrine System 13 | 18,159
Female tissues 13 | 17,400
Liver and Pancreas 13 | 16,750
Male tissues 13 | 17,142
Nervous System 13 | 16,725
Respiratory system 13 | 16,393
Skin and soft tissues 13 | 17,230
Urinary Tract 13 | 16,678
Cardiovascular System 12 | 15,192

Target Family

Non-IDG 7 | 12,091
Enzyme 6 | 4,145

GO Process

very long-chain fatty acid bio... 13 | 13
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

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