Development Level

Tbio 12 | 11,445
Tchem 3 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal behavior 1 | 298
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal forebrain development 1 | 20
abnormal heart morphology 1 | 162
abnormal neural tube closure 1 | 46
abnormal placenta size 1 | 20
abnormal vertebrae morphology 1 | 18
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating choleste... 1 | 93
decreased circulating fructosa... 1 | 30
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased lean body mass 1 | 135
decreased lumbar vertebrae num... 1 | 2
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged uterus 1 | 11
hydrometra 1 | 53
hyperactivity 1 | 148
increased monocyte cell number 1 | 63
pale yolk sac 1 | 25
pallor 1 | 34
preweaning lethality, incomple... 1 | 499
small superior vagus ganglion 1 | 74

Disease

Carcinoma 12 | 11,493
glioblastoma 9 | 5,792
osteosarcoma 9 | 7,950
ovarian cancer 9 | 8,520
Cancer 8 | 2,499
astrocytoma 7 | 1,146
Astrocytoma, Pilocytic 6 | 3,081
Kidney cancer 6 | 2,613
Tetralogy of Fallot 6 | 63
atypical teratoid / rhabdoid tumor 6 | 5,112
ependymoma 6 | 4,679
interstitial cystitis 6 | 2,312
lung cancer 6 | 4,740
Breast cancer 5 | 3,578
Cutis marmorata 5 | 32
Failure to gain weight 5 | 365
Pediatric failure to thrive 5 | 365
lung adenocarcinoma 5 | 2,716
lung carcinoma 5 | 2,843
medulloblastoma, large-cell 5 | 6,241
pancreatic cancer 5 | 2,398
Abnormally small eyeball 4 | 97
Brachydactyly 4 | 156
Breast Neoplasms 4 | 445
Cataract 4 | 297
Decreased size of eyeball 4 | 97
Mammary Neoplasms 4 | 425
Microphthalmos 4 | 100
Strabismus 4 | 270
adult high grade glioma 4 | 3,801
group 4 medulloblastoma 4 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
non-small cell lung cancer 4 | 2,890
psoriasis 4 | 6,694
Abnormality of pulmonary valve 3 | 23
Abnormality of the metacarpal bones 3 | 17
Absent toes 3 | 4
Adams Oliver syndrome 3 | 6
Adams-Oliver Syndrome 1 3 | 6
Adams-Oliver syndrome 3 | 15
Aplasia Cutis Congenita 3 | 14
Calvarial defect 3 | 10
Cardiomegaly 3 | 116
Claw hand 3 | 26
Cleft Palate 3 | 271
Congenital absence of hand 3 | 3
Congenital atresia of pulmonary artery 3 | 5
Congenital heart disease 3 | 93
Congenital scar 3 | 13
Cranial defect 3 | 10
Craniofacial Abnormalities 3 | 151
Endometriosis 3 | 540
Heart disease 3 | 306
Hereditary hemorrhagic telangiectasia 3 | 13
Hydrocephalus 3 | 152
Lens Opacities 3 | 231
Liver Cirrhosis 3 | 181
Short distal phalanges 3 | 50
Skull defect 3 | 10
Sparse hair 3 | 59
Syndactyly of fingers 3 | 48
Talipes 3 | 20
Talipes foot deformities 3 | 20
Thin, sparse hair 3 | 59
Ventricular Septal Defects 3 | 119
acute quadriplegic myopathy 3 | 1,158
cystic fibrosis 3 | 1,696
gastric carcinoma 3 | 807
group 3 medulloblastoma 3 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
invasive ductal carcinoma 3 | 2,951
malignant mesothelioma 3 | 3,232
oligodendroglioma 3 | 2,850
primitive neuroectodermal tumor 3 | 3,035
tuberculosis 3 | 2,010
Acquired scoliosis 2 | 281
Alzheimer's disease 2 | 658
Anemia 2 | 365
Byzanthine arch palate 2 | 194
Chemical and Drug Induced Liver Injury 2 | 195
Chest Pain 2 | 38
Coronary artery disease 2 | 268
Curvature of spine 2 | 282
Depressive disorder 2 | 409
Eye Abnormalities 2 | 35
Hemoglobin low 2 | 124
Highly variable clinical phenotype 2 | 150
Highly variable phenotype and severity 2 | 150
Highly variable phenotype, even within families 2 | 150
Hypertension 2 | 396
Hypothyroidism 2 | 122
Neuropathy 2 | 261
Osteoarthritis 2 | 184
Osteoporosis 2 | 363
Phenotypic variability 2 | 150
Polycystic ovary syndrome 2 | 360
Right atrial isomerism 2 | 29
Sensorineural hearing loss 2 | 106
Umbilical hernia 2 | 93
urothelial carcinoma 2 | 318

Tissue

Blood and immune system 15 | 16,909
Cardiovascular System 15 | 15,192
Digestive Tract 15 | 17,369
Endocrine System 15 | 18,159
Female tissues 15 | 17,400
Liver and Pancreas 15 | 16,750
Male tissues 15 | 17,142
Nervous System 15 | 16,725
Skin and soft tissues 15 | 17,230
Urinary Tract 15 | 16,678
Respiratory system 14 | 16,393

Target Family

Non-IDG 8 | 12,091
Transcription Factor 4 | 1,400
Kinase 2 | 634
Enzyme 1 | 4,145
Epigenetic 1 | 242

GO Process

ventricular trabecula myocardi... 16 | 16
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein HEG homolog 1 HEG1 Tbio Non-IDG -2.11308 129.3 11
Endoglin ENG Tbio Non-IDG -3.10482 1235.9 1622
Cerebral cavernous malformations 2 protein-like CCM2L Tdark Non-IDG -0.06695 1.24 54
Ubiquitin conjugation factor E4 B UBE4B Tbio Non-IDG -1.86207 73.2 141
Chromodomain-helicase-DNA-binding protein 7 CHD7 Tbio Epigenetic -2.91077 788.8 102
Bone morphogenetic protein receptor type-1A BMPR1A Tchem Kinase -2.34984 211.0 622
Transforming growth factor beta-2 TGFB2 Tbio Non-IDG -3.14427 1378.3 384
Homeobox protein Nkx-2.5 NKX2-5 Tbio Transcription Factor -2.79738 600.1 385
Forkhead box protein H1 FOXH1 Tbio Transcription Factor -2.20219 153.8 185
Recombining binding protein suppressor of hairless RBPJ Tbio Transcription Factor -2.67790 444.5 266