Development Level

Tbio 25 | 11,445
Tchem 2 | 1,598
Tdark 2 | 6,588

IMPC Phenotype

preweaning lethality, complete... 4 | 979
embryonic lethality prior to t... 3 | 278
decreased mean corpuscular vol... 2 | 79
decreased total body fat amoun... 2 | 207
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal cranium morphology 1 | 36
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal forebrain development 1 | 20
abnormal hindbrain development 1 | 16
abnormal incisor morphology 1 | 4
abnormal lens morphology 1 | 81
abnormal limb bud morphology 1 | 17
abnormal liver size 1 | 5
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal placenta size 1 | 20
abnormal radius morphology 1 | 8
abnormal response to new envir... 1 | 10
abnormal snout morphology 1 | 23
abnormal stomach morphology 1 | 10
abnormal tooth morphology 1 | 24
abnormal ulna morphology 1 | 8
cataract 1 | 92
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating choleste... 1 | 93
decreased circulating iron lev... 1 | 32
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased hematocrit 1 | 46
decreased lymphocyte cell numb... 1 | 83
decreased threshold for audito... 1 | 26
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
enlarged lymph nodes 1 | 37
increased blood urea nitrogen ... 1 | 48
increased circulating triglyce... 1 | 42
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 36
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
pale liver 1 | 6
pale yolk sac 1 | 25
pallor 1 | 34

Disease

Carcinoma 23 | 11,493
osteosarcoma 19 | 7,950
ovarian cancer 18 | 8,520
atypical teratoid / rhabdoid tumor 14 | 5,112
psoriasis 14 | 6,694
glioblastoma 13 | 5,792
lung cancer 13 | 4,740
Breast cancer 11 | 3,578
medulloblastoma, large-cell 11 | 6,241
Cancer 10 | 2,499
Kidney cancer 9 | 2,613
ependymoma 9 | 4,679
lung adenocarcinoma 9 | 2,716
pancreatic cancer 9 | 2,398
lung carcinoma 7 | 2,843
malignant mesothelioma 7 | 3,232
non-small cell lung cancer 7 | 2,890
pituitary cancer 7 | 1,972
primary pancreatic ductal adenocarcinoma 7 | 1,109
cystic fibrosis 6 | 1,696
group 4 medulloblastoma 6 | 1,855
interstitial cystitis 6 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
breast carcinoma 5 | 1,638
group 3 medulloblastoma 5 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
primitive neuroectodermal tumor 5 | 3,035
Holt-Oram syndrome 4 | 12
Intellectual disability 4 | 1,016
Melanoma 4 | 711
Rheumatoid arthritis 4 | 1,191
Skin cancer 4 | 469
Umbilical hernia 4 | 93
adult high grade glioma 4 | 3,801
gastric cancer 4 | 459
gastric carcinoma 4 | 807
invasive ductal carcinoma 4 | 2,951
nephrosclerosis 4 | 333
pancreatic carcinoma 4 | 562
Acquired metabolic disease 3 | 336
Amyotrophic lateral sclerosis 3 | 451
Arthritis, Rheumatoid 3 | 174
Astrocytoma, Pilocytic 3 | 3,081
Autosomal recessive predisposition 3 | 1,442
Big calvaria 3 | 147
Bilateral fifth finger clinodactyly 3 | 110
Brachydactyly 3 | 156
Broad forehead 3 | 59
Cardiomyopathy 3 | 116
Cognitive delay 3 | 608
Coloboma 3 | 51
Congenital diaphragmatic hernia 3 | 67
Congenital heart disease 3 | 93
Craniofacial Abnormalities 3 | 151
Cryptorchidism 3 | 296
Curvature of little finger 3 | 110
Diaphragmatic Hernia 3 | 40
Duane-radial ray syndrome 3 | 8
Dull intelligence 3 | 645
Endometrial cancer 3 | 311
Exophthalmos 3 | 112
Frontal bossing 3 | 157
Global developmental delay 3 | 608
Hernia, Diaphragmatic 3 | 40
Increased head circumference 3 | 147
Increased size of cranium 3 | 147
Increased size of skull 3 | 147
Liver cancer 3 | 604
Low intelligence 3 | 645
Mental Retardation 3 | 645
Mental and motor retardation 3 | 608
Mental deficiency 3 | 645
Polydactyly 3 | 107
Poor school performance 3 | 645
Prominent eyes 3 | 96
Prominent globes 3 | 96
Protruding eyes 3 | 96
Short nose 3 | 132
Small head 3 | 374
Small nose 3 | 132
Tetralogy of Fallot 3 | 63
Ventricular Septal Defects 3 | 119
acute quadriplegic myopathy 3 | 1,158
colon cancer 3 | 1,478
cutaneous lupus erythematosus 3 | 1,057
ductal carcinoma in situ 3 | 1,745
juvenile dermatomyositis 3 | 1,187
oligodendroglioma 3 | 2,850
pediatric high grade glioma 3 | 1,064
spina bifida 3 | 1,074
subependymal giant cell astrocytoma 3 | 2,287
ulcerative colitis 3 | 1,819
Depressed nasal bridge 2 | 195
Epilepsy 2 | 792
Male infertility 2 | 206
Thin lips 2 | 49
progressive supranuclear palsy 2 | 676
tuberculosis 2 | 2,010
urothelial carcinoma 2 | 318

Tissue

Digestive Tract 29 | 17,369
Endocrine System 29 | 18,159
Female tissues 29 | 17,400
Male tissues 29 | 17,142
Liver and Pancreas 28 | 16,750
Skin and soft tissues 28 | 17,230
Blood and immune system 27 | 16,909
Cardiovascular System 27 | 15,192
Respiratory system 27 | 16,393
Urinary Tract 27 | 16,678
Nervous System 25 | 16,725

Target Family

Non-IDG 17 | 12,091
Transcription Factor 8 | 1,400
Enzyme 2 | 4,145
Kinase 1 | 634
TF/Epigenetic 1 | 38

GO Process

ventricular septum development 29 | 29
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein HEG homolog 1 HEG1 Tbio Non-IDG -2.11308 129.3 11
Sal-like protein 4 SALL4 Tbio Transcription Factor -2.64737 454.3 165
Latent-transforming growth factor beta-binding protein 1 LTBP1 Tbio Non-IDG -1.97590 101.5 128
Xin actin-binding repeat-containing protein 2 XIRP2 Tbio Non-IDG -0.94115 9.06 17
Leucine zipper protein 1 LUZP1 Tdark Non-IDG -0.56441 4.08 85
Mothers against decapentaplegic homolog 6 SMAD6 Tbio Transcription Factor -2.07569 106.7 450
Receptor for retinol uptake STRA6 STRA6 Tbio Non-IDG -1.78205 67.9 157
Gap junction alpha-5 protein GJA5 Tbio Non-IDG -2.59423 377.5 194
LIM domain transcription factor LMO4 LMO4 Tbio Non-IDG -1.08353 14.5 216
Paired box protein Pax-8 PAX8 Tbio Transcription Factor -2.64765 442.1 540