Development Level

Tbio 19 | 11,445
Tclin 4 | 613
Tchem 1 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal heart morphology 1 | 162
abnormal response to new envir... 1 | 10
decreased body weight 1 | 161
decreased circulating amylase ... 1 | 28
decreased circulating creatini... 1 | 39
decreased mean corpuscular vol... 1 | 79
embryonic lethality prior to t... 1 | 278
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
increased circulating HDL chol... 1 | 80
increased circulating chloride... 1 | 41
increased heart weight 1 | 62
increased startle reflex 1 | 112
long tibia 1 | 25

Disease

Carcinoma 16 | 11,493
medulloblastoma, large-cell 11 | 6,241
Cardiomyopathy 10 | 116
Dilated cardiomyopathy 10 | 56
Hypertrophic Cardiomyopathy 10 | 117
malignant mesothelioma 10 | 3,232
ovarian cancer 10 | 8,520
psoriasis 10 | 6,694
cystic fibrosis 9 | 1,696
glioblastoma 9 | 5,792
lung cancer 9 | 4,740
osteosarcoma 9 | 7,950
Cancer 8 | 2,499
lung carcinoma 8 | 2,843
Cardiomyopathy, Dilated 7 | 83
Cardiomyopathy, Hypertrophic, Familial 7 | 9
Congestive heart failure 7 | 113
Familial isolated dilated cardiomyopathy 7 | 41
LEFT VENTRICULAR NONCOMPACTION 10 7 | 40
LEFT VENTRICULAR NONCOMPACTION 8 7 | 40
Left ventricular noncompaction 7 | 26
acute quadriplegic myopathy 7 | 1,158
adult high grade glioma 7 | 3,801
Breast cancer 6 | 3,578
Congenital heart disease 6 | 93
Heart disease 6 | 306
Kidney cancer 6 | 2,613
atypical teratoid / rhabdoid tumor 6 | 5,112
colon cancer 6 | 1,478
Autosomal recessive predisposition 5 | 1,442
Heart failure 5 | 162
Liver cancer 5 | 604
Pick disease 5 | 1,894
group 3 medulloblastoma 5 | 4,104
interstitial cystitis 5 | 2,312
lung adenocarcinoma 5 | 2,716
pancreatic cancer 5 | 2,398
pituitary cancer 5 | 1,972
Atrial Septal Defects 4 | 85
Bipolar Disorder 4 | 666
Cardiomyopathy, Familial Hypertrophic, 1 4 | 6
Cardiomyopathy, Hypertrophic 4 | 24
Cleft Palate 4 | 271
Exophthalmos 4 | 112
Myocardial Infarction 4 | 151
Myopathy 4 | 185
Prominent eyes 4 | 96
Prominent globes 4 | 96
Protruding eyes 4 | 96
Restrictive cardiomyopathy 4 | 11
breast carcinoma 4 | 1,638
diabetes mellitus 4 | 1,728
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
invasive ductal carcinoma 4 | 2,951
non-small cell lung cancer 4 | 2,890
primitive neuroectodermal tumor 4 | 3,035
Acquired scoliosis 3 | 281
Astrocytoma, Pilocytic 3 | 3,081
Atopic dermatitis 3 | 952
Blepharoptosis 3 | 231
Cardiac Arrhythmia 3 | 103
Cardiac conduction abnormalities 3 | 78
Cardiomyopathies 3 | 110
Cataract 3 | 297
Cerebrovascular disease 3 | 238
Conduction disorder of the heart 3 | 79
Congenital deafness 3 | 185
Coronary artery disease 3 | 268
Craniofacial Abnormalities 3 | 151
Curvature of spine 3 | 282
Deafness 3 | 198
Decreased projection of midface 3 | 105
Dental caries 3 | 164
Distal arthrogryposis 3 | 42
EKG abnormalities 3 | 78
Electrocardiogram abnormal 3 | 81
Electrocardiogram change 3 | 78
Glaucoma 3 | 239
Hearing Loss, Partial 3 | 185
Hypertension 3 | 396
Hypertensive disease 3 | 292
Hypotrophic malar bone 3 | 129
Hypotrophic midface 3 | 105
Lens Opacities 3 | 231
Liver Cirrhosis, Experimental 3 | 769
Malar flattening 3 | 129
Melanoma 3 | 711
Midface retrusion 3 | 105
Orbital separation excessive 3 | 244
Patent ductus arteriosus 3 | 90
Prostatic Neoplasms 3 | 495
Skin cancer 3 | 469
Small midface 3 | 105
Sudden Cardiac Death 3 | 29
Tachycardia, Ventricular 3 | 22
hearing impairment 3 | 199
medulloblastoma 3 | 720
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
pediatric high grade glioma 3 | 1,064
subependymal giant cell astrocytoma 3 | 2,287

Tissue

Digestive Tract 25 | 17,369
Endocrine System 25 | 18,159
Female tissues 25 | 17,400
Liver and Pancreas 25 | 16,750
Male tissues 24 | 17,142
Skin and soft tissues 24 | 17,230
Blood and immune system 23 | 16,909
Cardiovascular System 23 | 15,192
Urinary Tract 23 | 16,678
Nervous System 22 | 16,725
Respiratory system 21 | 16,393

Target Family

Non-IDG 16 | 12,091
Transcription Factor 6 | 1,400
Enzyme 1 | 4,145
Kinase 1 | 634
Nuclear Receptor 1 | 48

GO Process

ventricular cardiac muscle tis... 25 | 25
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Plakophilin-2 PKP2 Tbio Non-IDG -2.10355 135.3 243
Forkhead box protein C2 FOXC2 Tbio Transcription Factor -2.23435 187.0 419
Pentatricopeptide repeat-containing protein 2, mitochondrial PTCD2 Tdark Non-IDG -0.06695 1.01 131
Myosin-6 MYH6 Tbio Non-IDG -2.95952 901.3 45
Collagen alpha-1(XI) chain COL11A1 Tbio Non-IDG -2.15516 138.4 96
Insulin gene enhancer protein ISL-1 ISL1 Tbio Transcription Factor -2.63352 410.3 382
Forkhead box protein C1 FOXC1 Tbio Transcription Factor -2.28586 201.8 314
Prospero homeobox protein 1 PROX1 Tbio Transcription Factor -2.31691 210.1 472
Troponin I, slow skeletal muscle TNNI1 Tbio Non-IDG -1.62315 40.3 210
Myosin-7 MYH7 Tbio Non-IDG -2.64013 417.6 176