Development Level

Tbio 8 | 11,651
Tchem 2 | 1,388

IMPC Phenotype

preweaning lethality, complete... 4 | 979
abnormal behavior 1 | 298
abnormal optic disc morphology 1 | 10
abnormal retina morphology 1 | 71
abnormal tooth morphology 1 | 24
corneal opacity 1 | 32
decreased circulating creatini... 1 | 39
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
increased circulating HDL chol... 1 | 80
irregularly shaped pupil 1 | 7
prenatal lethality 1 | 28
small testis 1 | 58
urinary bladder obstruction 1 | 4

Disease

lung cancer 6 | 4,740
ovarian cancer 6 | 8,520
psoriasis 6 | 6,694
glioblastoma 5 | 5,792
Breast cancer 4 | 3,578
Cancer 4 | 2,499
Congenital heart disease 4 | 93
atypical teratoid / rhabdoid tumor 4 | 5,112
ependymoma 4 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
medulloblastoma, large-cell 4 | 6,241
non-small cell lung cancer 4 | 2,890
pancreatic cancer 4 | 2,398
ATRIAL FIBRILLATION, FAMILIAL, 1 (disorder) 3 | 21
Astrocytoma, Pilocytic 3 | 3,081
Atrial Fibrillation 3 | 124
Autosomal recessive predisposition 3 | 1,442
Cardiomyopathy, Dilated 3 | 83
Hypothyroidism 3 | 122
Mammary Neoplasms 3 | 425
adrenocortical carcinoma 3 | 1,428
adult high grade glioma 3 | 3,801
interstitial cystitis 3 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
lung adenocarcinoma 3 | 2,716
nasopharyngeal carcinoma 3 | 1,058
osteosarcoma 3 | 7,950
pituitary cancer 3 | 1,972
primary Sjogren syndrome 3 | 735
primitive neuroectodermal tumor 3 | 3,035
ulcerative colitis 3 | 1,819
Atopic dermatitis 2 | 952
Brachydactyly 2 | 156
Breast Neoplasms 2 | 445
Broad flat nasal bridge 2 | 236
Cardiac Arrhythmia 2 | 103
Cardiac conduction abnormalities 2 | 78
Cardiomegaly 2 | 116
Cardiomyopathy 2 | 116
Cognitive delay 2 | 608
Conduction disorder of the heart 2 | 79
Congestive heart failure 2 | 113
Conotruncal Heart Malformations 2 | 10
Craniofacial Abnormalities 2 | 151
EKG abnormalities 2 | 78
Electrocardiogram abnormal 2 | 81
Electrocardiogram change 2 | 78
Endometriosis 2 | 540
Exophthalmos 2 | 112
Familial atrial fibrillation 2 | 23
Fatigue 2 | 182
Feeding difficulties 2 | 127
Glaucoma 2 | 239
Global developmental delay 2 | 608
Growth delay 2 | 114
Growth failure 2 | 114
Growth retardation 2 | 115
Hepatomegaly 2 | 285
Highly variable severity 2 | 157
Hypodontia 2 | 81
Intrauterine retardation 2 | 176
Large bregma sutures 2 | 46
Large fontanelle 2 | 46
Large, late-closing fontanelle 2 | 46
Liver Cirrhosis, Experimental 2 | 769
Mental and motor retardation 2 | 608
Midface retrusion 2 | 105
Myocardial Infarction 2 | 151
Nasal bridge wide 2 | 236
Neurodegenerative disease 2 | 414
Penile hypospadias 2 | 106
Polycystic ovary syndrome 2 | 360
Poor growth 2 | 114
Prominent eyes 2 | 96
Prominent globes 2 | 96
Protruding eyes 2 | 96
Right atrial isomerism 2 | 29
Short stature 2 | 531
Small midface 2 | 105
Tetralogy of Fallot 2 | 67
Thin lips 2 | 49
Variable expressivity 2 | 157
Ventricular Septal Defects 2 | 119
Very poor growth 2 | 114
Wide bregma sutures 2 | 46
astrocytic glioma 2 | 2,597
astrocytoma 2 | 1,146
breast carcinoma 2 | 1,638
colon cancer 2 | 1,478
ductal carcinoma in situ 2 | 1,745
group 3 medulloblastoma 2 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
invasive ductal carcinoma 2 | 2,951
lung carcinoma 2 | 2,843
oligodendroglioma 2 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
sonic hedgehog group medulloblastoma 2 | 467
spina bifida 2 | 1,074
tuberculosis 2 | 2,010
ventricular septal defect 2 | 20

Tissue

Cardiovascular System 9 | 15,192
Female tissues 9 | 17,400
Digestive Tract 8 | 17,369
Endocrine System 8 | 18,159
Liver and Pancreas 8 | 16,750
Urinary Tract 8 | 16,678
Blood and immune system 7 | 16,909
Male tissues 7 | 17,142
Skin and soft tissues 7 | 17,230
Nervous System 6 | 16,725
Respiratory system 6 | 16,393

Target Family

Non-IDG 5 | 12,091
Transcription Factor 4 | 1,400
Kinase 1 | 634

GO Process

ventricular cardiac muscle cel... 10 | 10
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Pituitary homeobox 2 PITX2 Tbio Transcription Factor -2.67290 480.0 220
G2/mitotic-specific cyclin-B1 CCNB1 Tchem Non-IDG -3.14393 1189.3 1251
Prelamin-A/C LMNA Tbio Non-IDG -3.03952 1089.9 1005
Homeobox protein Nkx-2.5 NKX2-5 Tbio Transcription Factor -2.79738 600.1 385
Autophagy protein 5 ATG5 Tbio Non-IDG -2.88619 656.2 666
Homeobox protein Nkx-2.6 NKX2-6 Tbio Transcription Factor -3.04651 1092.2 134
Four and a half LIM domains protein 2 FHL2 Tbio Non-IDG -2.60042 385.8 253
Bone morphogenetic protein 10 BMP10 Tbio Non-IDG -1.43436 26.2 268
Hairy/enhancer-of-split related with YRPW motif protein 2 HEY2 Tbio Transcription Factor -2.43307 261.2 173
Cyclin-dependent kinase 1 CDK1 Tchem Kinase -3.28086 1790.3 1933