Development Level

Tbio 11 | 11,445
Tclin 4 | 613

Collection

Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal retina morphology 1 | 71
absent startle reflex 1 | 24
decreased body length 1 | 101
decreased circulating iron lev... 1 | 32
decreased erythrocyte cell num... 1 | 62
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
embryonic lethality prior to t... 1 | 278
hypoactivity 1 | 132
increased circulating magnesiu... 1 | 10
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499

Disease

Long QT syndrome 11 | 39
Carcinoma 10 | 11,493
Syncope 10 | 22
Atrial Fibrillation 9 | 124
Brugada syndrome 9 | 29
Cardiomyopathy 9 | 116
Romano-Ward Syndrome 8 | 12
ovarian cancer 8 | 8,520
psoriasis 8 | 6,694
Cardiac Arrhythmia 7 | 103
Familial atrial fibrillation 7 | 23
Long QT syndrome 1 7 | 20
Prolonged QT interval 7 | 15
Sudden Cardiac Death 7 | 29
Sudden infant death syndrome 7 | 32
Ventricular Fibrillation 7 | 17
atypical teratoid / rhabdoid tumor 7 | 5,112
glioblastoma 7 | 5,792
ATRIAL FIBRILLATION, FAMILIAL, 1 (disorder) 6 | 21
Breast cancer 6 | 3,578
Short QT syndrome 6 | 12
Torsades de Pointes 6 | 8
adult high grade glioma 6 | 3,801
ependymoma 6 | 4,679
lung carcinoma 6 | 2,843
medulloblastoma, large-cell 6 | 6,241
osteosarcoma 6 | 7,950
Astrocytoma, Pilocytic 5 | 3,081
Atrioventricular block 5 | 35
Cardiac arrest 5 | 36
Catecholaminergic polymorphic ventricular tachycardia 5 | 12
Kidney cancer 5 | 2,613
Timothy syndrome 5 | 11
lung adenocarcinoma 5 | 2,716
lung cancer 5 | 4,740
malignant mesothelioma 5 | 3,232
primitive neuroectodermal tumor 5 | 3,035
Autosomal recessive predisposition 4 | 1,442
Heart conduction disease 4 | 83
Heart disease 4 | 306
Ventricular arrhythmia 4 | 27
adrenocortical carcinoma 4 | 1,428
astrocytic glioma 4 | 2,597
group 3 medulloblastoma 4 | 4,104
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
non-small cell lung cancer 4 | 2,890
oligodendroglioma 4 | 2,850
Brugada Syndrome (disorder) 3 | 15
Epilepsy 3 | 792
Liver cancer 3 | 604
Palpitations 3 | 18
Pick disease 3 | 1,894
Right bundle branch block 3 | 17
Sudden death 3 | 16
colon cancer 3 | 1,478
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
pancreatic cancer 3 | 2,398
pituitary cancer 3 | 1,972
Arrhythmogenic right ventricular cardiomyopathy 2 | 30
Atrial Fibrillation, Familial, 3 2 | 2
Autism spectrum disorder 2 | 101
Cardiac conduction abnormalities 2 | 78
Cardiomegaly 2 | 116
Cardioversion of Atrial Fibrillation 2 | 9
Conduction disorder of the heart 2 | 79
DOID:2627 2 | 94
Dilated cardiomyopathy 2 | 56
Disease of mental health 2 | 36
EKG abnormalities 2 | 78
Eaton-Lambert syndrome 2 | 40
Electrocardiogram abnormal 2 | 81
Electrocardiogram change 2 | 78
Endometrial cancer 2 | 311
Exophthalmos 2 | 112
Hearing Loss, Noise-Induced 2 | 5
Hypertension 2 | 396
Hypokalemia 2 | 52
Jervell-Lange Nielsen syndrome 2 | 4
Life-Threatening Ventricular Tachycardia 2 | 15
Multiple Sclerosis 2 | 540
Myopathy 2 | 185
Noise-induced hearing loss 2 | 5
Prominent eyes 2 | 96
Prominent globes 2 | 96
Protruding eyes 2 | 96
Schizophrenia 2 | 1,160
Sensorineural hearing loss 2 | 106
Status Epilepticus 2 | 98
Tachycardia 2 | 43
Thin lips 2 | 49
acute myeloid leukemia 2 | 783
breast carcinoma 2 | 1,638
cystic fibrosis 2 | 1,696
ductal carcinoma in situ 2 | 1,745
gastric carcinoma 2 | 807
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
invasive ductal carcinoma 2 | 2,951
medulloblastoma 2 | 720
subependymal giant cell astrocytoma 2 | 2,287

Tissue

Blood and immune system 15 | 16,909
Cardiovascular System 15 | 15,192
Digestive Tract 15 | 17,369
Endocrine System 15 | 18,159
Female tissues 15 | 17,400
Liver and Pancreas 15 | 16,750
Male tissues 15 | 17,142
Respiratory system 15 | 16,393
Skin and soft tissues 15 | 17,230
Urinary Tract 14 | 16,678
Nervous System 13 | 16,725

Target Family

Ion Channel 7 | 344
Non-IDG 6 | 12,091
Enzyme 2 | 4,145

GO Process

ventricular cardiac muscle cel... 15 | 15
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Plakophilin-2 PKP2 Tbio Non-IDG -2.10355 135.3 243
Alpha-1-syntrophin SNTA1 Tbio Non-IDG -1.49227 31.4 254
Ankyrin-2 ANK2 Tbio Non-IDG -2.08421 120.5 236
Potassium voltage-gated channel subfamily E regulatory beta subunit 5 KCNE5 Tbio Non-IDG -0.91945 8.20 84
Potassium voltage-gated channel subfamily H member 2 KCNH2 Tclin Ion Channel -3.22575 1653.9 243
Potassium voltage-gated channel subfamily KQT member 1 KCNQ1 Tclin Ion Channel -2.90675 800.2 365
Gap junction alpha-5 protein GJA5 Tbio Non-IDG -2.59423 377.5 194
Ryanodine receptor 2 RYR2 Tclin Ion Channel -2.92980 851.9 138
Glycerol-3-phosphate dehydrogenase 1-like protein GPD1L Tbio Enzyme -1.31283 20.2 132
E3 ubiquitin-protein ligase NEDD4-like NEDD4L Tbio Enzyme -2.52486 353.9 144