Development Level

Tbio 3 | 11,445
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, complete... 1 | 979
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36

Disease

Hypertension 4 | 396
Autosomal recessive predisposition 3 | 1,442
Bradycardia 3 | 36
Breast cancer 3 | 3,578
Cancer 3 | 2,499
Hypotension 3 | 82
breast carcinoma 3 | 1,638
group 3 medulloblastoma 3 | 4,104
lung cancer 3 | 4,740
ulcerative colitis 3 | 1,819
Abdominal Pain 2 | 98
Abnormality of vision 2 | 40
Blonde eyebrow 2 | 5
Broad flat nasal bridge 2 | 236
Carcinoma 2 | 11,493
Cardiovascular Abnormalities 2 | 31
Cardiovascular Diseases 2 | 59
Congenital central hypoventilation syndrome 2 | 18
Congenital deafness 2 | 185
Constipation 2 | 181
Convex nasal bridge 2 | 57
Deafness 2 | 198
Diabetes Mellitus, Non-Insulin-Dependent 2 | 145
Diabetes Mellitus, Type 2 2 | 142
Diaphragmatic Hernia 2 | 40
Disorder of macula of retina 2 | 6
Dyschezia 2 | 135
Grey eyebrow 2 | 5
Grey eyelashes 2 | 5
Hearing Loss, Partial 2 | 185
Heart disease 2 | 306
Heart failure 2 | 162
Hepatopulmonary syndrome 2 | 6
Hernia, Diaphragmatic 2 | 40
Heterochromia iridis 2 | 9
Hirschsprung Disease 2 | 31
Hirschsprung's disease 2 | 46
Hypertension, Pulmonary 2 | 37
Hypertensive disease 2 | 292
Intestinal Obstruction 2 | 31
Kidney disease 2 | 430
Megacolon 2 | 29
Nasal bridge wide 2 | 236
Nausea and vomiting 2 | 97
Nephrosis 2 | 21
Olfactory lobe absence 2 | 6
Premature canities 2 | 24
Prominent nasal bridge 2 | 57
Pulmonary hypertension 2 | 85
Sensorineural Hearing Loss (disorder) 2 | 284
Sensorineural hearing loss 2 | 106
Subarachnoid Hemorrhage 2 | 7
Synophrys 2 | 40
Thin hypoplastic alae nasi 2 | 51
WAARDENBURG SYNDROME, TYPE 4A 2 | 3
Waardenburg's syndrome 2 | 17
Waardenburg-Shah syndrome 2 | 3
Weight decreased 2 | 103
White eyebrows 2 | 5
White eyelashes 2 | 5
White forelock 2 | 12
blue iris (physical finding) 2 | 17
colon cancer 2 | 1,478
ductal carcinoma in situ 2 | 1,745
ependymoma 2 | 4,679
hearing impairment 2 | 199
hypopigmented skin patch 2 | 59
invasive ductal carcinoma 2 | 2,951
lung adenocarcinoma 2 | 2,716
lung carcinoma 2 | 2,843
malignant mesothelioma 2 | 3,232
medulloblastoma, large-cell 2 | 6,241
non-small cell lung cancer 2 | 2,890
ovarian cancer 2 | 8,520
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
Abnormal auditory evoked potential 1 | 7
Achromasia 1 | 11
Albinism 1 | 11
Cardiomegaly 1 | 116
Cell Transformation, Neoplastic 1 | 97
Congenital diaphragmatic hernia 1 | 67
Diabetes Mellitus, Experimental 1 | 108
Ganglioneuroma 1 | 13
Glossoptosis 1 | 10
Hyperglycemia 1 | 137
Hypertrophy 1 | 17
Hypertrophy, Left Ventricular 1 | 24
Infarction, Middle Cerebral Artery 1 | 33
Left Ventricular Hypertrophy 1 | 47
Lewy Body Disease 1 | 21
Myocardial Reperfusion Injury 1 | 37
Neoplastic Cell Transformation 1 | 89
Pain 1 | 103
Paraparesis, Spastic 1 | 16
Peripheral Neuropathy 1 | 134
Posterior displacement of the tongue 1 | 10
Pre-Eclampsia 1 | 68
Pulmonary Fibrosis 1 | 106
Systemic scleroderma 1 | 60
Toxic shock syndrome 1 | 28

Tissue

Blood and immune system 4 | 16,909
Digestive Tract 4 | 17,369
Endocrine System 4 | 18,159
Female tissues 4 | 17,400
Liver and Pancreas 4 | 16,750
Male tissues 4 | 17,142
Respiratory system 4 | 16,393
Skin and soft tissues 4 | 17,230
Urinary Tract 4 | 16,678
Cardiovascular System 3 | 15,192
Nervous System 3 | 16,725

Target Family

Non-IDG 3 | 12,091
GPCR 1 | 408

GO Process

vein smooth muscle contraction 4 | 4
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Endothelin-3 EDN3 Tbio Non-IDG -2.96371 794.0 219
Endothelin-2 EDN2 Tbio Non-IDG -2.65568 390.3 131
Endothelin receptor type B EDNRB Tclin GPCR -3.27771 1756.7 324
Endothelin-1 EDN1 Tbio Non-IDG -4.07520 12851.9 607