Development Level

Tbio 39 | 11,445
Tchem 9 | 1,598
Tclin 6 | 613
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 8 | 979
embryonic lethality prior to t... 5 | 278
enlarged heart 4 | 210
abnormal pericardium morpholog... 3 | 26
preweaning lethality, incomple... 3 | 499
abnormal behavior 2 | 298
abnormal embryo size 2 | 220
decreased body weight 2 | 161
decreased vertical activity 2 | 208
edema 2 | 59
embryonic lethality prior to o... 2 | 239
hydrometra 2 | 53
abnormal bone structure 1 | 187
abnormal embryo development 1 | 7
abnormal embryo turning 1 | 31
abnormal eye morphology 1 | 68
abnormal eye size 1 | 7
abnormal forebrain development 1 | 20
abnormal heart morphology 1 | 162
abnormal hindbrain development 1 | 16
abnormal lung morphology 1 | 26
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal optic disc morphology 1 | 10
abnormal rib morphology 1 | 10
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal spinal cord morpholog... 1 | 9
abnormal spleen morphology 1 | 55
abnormal tooth morphology 1 | 24
corneal opacity 1 | 32
decreased blood urea nitrogen ... 1 | 51
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased prepulse inhibition 1 | 82
decreased total retina thickne... 1 | 17
enlarged spleen 1 | 41
hydrops fetalis 1 | 1
impaired glucose tolerance 1 | 75
increased circulating HDL chol... 1 | 80
increased heart rate variabili... 1 | 7
increased leukocyte cell numbe... 1 | 47
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
irregularly shaped pupil 1 | 7
limb grasping 1 | 41
microphthalmia 1 | 26
pale yolk sac 1 | 25
pallor 1 | 34
prenatal lethality 1 | 28
scaly skin 1 | 4
small superior vagus ganglion 1 | 74
small testis 1 | 58

Disease

Carcinoma 37 | 11,493
glioblastoma 30 | 5,792
lung cancer 29 | 4,740
ovarian cancer 29 | 8,520
non-small cell lung cancer 27 | 2,890
osteosarcoma 26 | 7,950
Cancer 22 | 2,499
invasive ductal carcinoma 22 | 2,951
psoriasis 22 | 6,694
intraductal papillary-mucinous neoplasm (IPMN) 21 | 3,291
lung carcinoma 20 | 2,843
atypical teratoid / rhabdoid tumor 19 | 5,112
intraductal papillary-mucinous carcinoma (IPMC) 19 | 2,989
Breast cancer 18 | 3,578
ependymoma 18 | 4,679
lung adenocarcinoma 18 | 2,716
medulloblastoma, large-cell 18 | 6,241
malignant mesothelioma 15 | 3,232
ulcerative colitis 15 | 1,819
Astrocytoma, Pilocytic 14 | 3,081
adult high grade glioma 14 | 3,801
group 3 medulloblastoma 14 | 4,104
interstitial cystitis 14 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 14 | 2,955
pancreatic cancer 14 | 2,398
cystic fibrosis 13 | 1,696
ductal carcinoma in situ 12 | 1,745
breast carcinoma 11 | 1,638
pituitary cancer 11 | 1,972
tuberculosis 11 | 2,010
Autosomal recessive predisposition 10 | 1,442
Heart disease 10 | 306
Kidney cancer 10 | 2,613
diabetes mellitus 10 | 1,728
group 4 medulloblastoma 10 | 1,855
primitive neuroectodermal tumor 10 | 3,035
Hypertension 9 | 396
astrocytoma 9 | 1,146
Schizophrenia 8 | 1,160
acute quadriplegic myopathy 8 | 1,158
adrenocortical carcinoma 8 | 1,428
oligodendroglioma 8 | 2,850
primary pancreatic ductal adenocarcinoma 8 | 1,109
Bipolar Disorder 7 | 666
Cerebrovascular disease 7 | 238
astrocytic glioma 7 | 2,597
colon cancer 7 | 1,478
fibroadenoma 7 | 559
gastric carcinoma 7 | 807
juvenile dermatomyositis 7 | 1,187
Atherosclerosis 6 | 291
Atopic dermatitis 6 | 952
Coronary artery disease 6 | 268
Glaucoma 6 | 239
Hemangioma 6 | 69
Hypertensive disease 6 | 292
Liver Cirrhosis, Experimental 6 | 769
Rheumatoid arthritis 6 | 1,191
Telangiectasis 6 | 36
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 510
dermatomyositis 6 | 966
nephrosclerosis 6 | 333
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
spina bifida 6 | 1,074
subependymal giant cell astrocytoma 6 | 2,287
urothelial carcinoma 6 | 318
Alzheimer's disease 5 | 658
Breast Neoplasms 5 | 445
Colorectal Neoplasms 5 | 243
Kidney disease 5 | 430
Lung Neoplasms 5 | 232
Mammary Neoplasms 5 | 425
Multiple Sclerosis 5 | 540
Multiple cutaneous and mucosal venous malformations 5 | 10
Neoplasm Metastasis 5 | 168
Pick disease 5 | 1,894
Short stature 5 | 531
Squamous cell carcinoma 5 | 129
Telangiectasia of the skin 5 | 39
aldosterone-producing adenoma 5 | 665
chronic rhinosinusitis 5 | 512
gastric cancer 5 | 459
nasopharyngeal carcinoma 5 | 1,058
Arthritis 4 | 290
Bilateral fifth finger clinodactyly 4 | 110
Curvature of little finger 4 | 110
Depressive disorder 4 | 409
Down syndrome 4 | 499
Duchenne muscular dystrophy 4 | 601
Epilepsy 4 | 792
Liver carcinoma 4 | 240
Lung disease 4 | 142
Major Depressive Disorder 4 | 301
Prostatic Neoplasms 4 | 495
Type 2 diabetes mellitus 4 | 272
active ulcerative colitis 4 | 764
acute myeloid leukemia 4 | 783
hepatocellular carcinoma 4 | 547
mucosa-associated lymphoid tissue lymphoma 4 | 484
pediatric high grade glioma 4 | 1,064

Tissue

Endocrine System 54 | 18,159
Female tissues 54 | 17,400
Digestive Tract 53 | 17,369
Liver and Pancreas 53 | 16,750
Skin and soft tissues 53 | 17,230
Urinary Tract 53 | 16,678
Blood and immune system 52 | 16,909
Cardiovascular System 52 | 15,192
Male tissues 52 | 17,142
Nervous System 51 | 16,725
Respiratory system 51 | 16,393

Target Family

Non-IDG 26 | 12,091
Transcription Factor 14 | 1,400
Kinase 6 | 634
Enzyme 5 | 4,145
GPCR 3 | 408
Epigenetic 1 | 242

GO Process

vasculogenesis 55 | 55
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein HEG homolog 1 HEG1 Tbio Non-IDG -2.11308 129.3 11
Endoglin ENG Tbio Non-IDG -3.10482 1235.9 1622
Growth/differentiation factor 2 GDF2 Tbio Non-IDG -2.16825 176.4 239
Zinc finger protein ZFPM2 ZFPM2 Tbio Transcription Factor -1.78912 62.9 93
Smoothened homolog SMO Tclin GPCR -1.17466 14.5 415
Transmembrane protein 100 TMEM100 Tbio Non-IDG -0.92226 8.79 100
Epidermal growth factor-like protein 7 EGFL7 Tbio Non-IDG -1.78690 72.8 217
Brachyury protein TBXT Tbio Transcription Factor -2.24737 158.4 337
Zinc finger MIZ domain-containing protein 1 ZMIZ1 Tbio Transcription Factor -1.57174 37.9 126
Cullin-7 CUL7 Tbio Non-IDG -1.49747 38.0 139