Development Level

Tbio 11 | 11,445
Tdark 3 | 6,588

IMPC Phenotype

preweaning lethality, complete... 4 | 979
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
abnormal kidney morphology 1 | 65
abnormal seminal vesicle morph... 1 | 114
cardiovascular system phenotyp... 1 | 36
decreased bone mineral content 1 | 151
decreased circulating choleste... 1 | 93
decreased total body fat amoun... 1 | 207
increased bone mineral content 1 | 108
increased total body fat amoun... 1 | 134
short tibia 1 | 97

Disease

Carcinoma 10 | 11,493
glioblastoma 8 | 5,792
ovarian cancer 8 | 8,520
medulloblastoma, large-cell 7 | 6,241
ependymoma 6 | 4,679
lung carcinoma 6 | 2,843
psoriasis 6 | 6,694
osteosarcoma 5 | 7,950
Astrocytoma, Pilocytic 4 | 3,081
Autosomal recessive predisposition 4 | 1,442
Kidney cancer 4 | 2,613
Multiple myeloma 4 | 1,332
atypical teratoid / rhabdoid tumor 4 | 5,112
group 3 medulloblastoma 4 | 4,104
Failure to gain weight 3 | 365
Osteopetrosis 3 | 43
Pediatric failure to thrive 3 | 365
Pick disease 3 | 1,894
adult high grade glioma 3 | 3,801
astrocytic glioma 3 | 2,597
diabetes mellitus 3 | 1,728
mucosa-associated lymphoid tissue lymphoma 3 | 484
oligodendroglioma 3 | 2,850
pancreatic cancer 3 | 2,398
primitive neuroectodermal tumor 3 | 3,035
Anemia 2 | 365
Breast cancer 2 | 3,578
Dental caries 2 | 164
Down syndrome 2 | 499
Dull intelligence 2 | 645
Endometrial cancer 2 | 311
Epilepsy 2 | 792
Frontal bossing 2 | 157
Growth delay 2 | 114
Growth failure 2 | 114
Growth retardation 2 | 115
Hip joint varus deformity - observation 2 | 24
Intellectual disability 2 | 1,016
Late tooth eruption 2 | 61
Liver cancer 2 | 604
Low intelligence 2 | 645
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Motor delay 2 | 147
No development of motor milestones 2 | 147
Poor growth 2 | 114
Poor school performance 2 | 645
Rheumatoid arthritis 2 | 1,191
Rotting teeth 2 | 73
Seizures 2 | 596
Short stature 2 | 531
Very poor growth 2 | 114
dermatomyositis 2 | 966
invasive ductal carcinoma 2 | 2,951
lung cancer 2 | 4,740
malignant mesothelioma 2 | 3,232
non-small cell lung cancer 2 | 2,890
pediatric high grade glioma 2 | 1,064
primary pancreatic ductal adenocarcinoma 2 | 1,109
progressive supranuclear palsy 2 | 676
sarcoidosis 2 | 370
subependymal giant cell astrocytoma 2 | 2,287
tuberculosis 2 | 2,010
Acquired flat foot 1 | 72
Alkaline phosphatase serum increased 1 | 29
Borna disease 1 | 6
Calcinosis 1 | 70
Coarse hair 1 | 31
Decreased projection of midface 1 | 105
Decreased size of teeth 1 | 62
Decreased width of tooth 1 | 59
Dehydration 1 | 40
Ethylmalonic encephalopathy 1 | 12
Flatfoot 1 | 73
Food allergy 1 | 8
Fragile nails 1 | 16
Generalized osteopenia 1 | 99
Glioma 1 | 74
Gynecomastia 1 | 64
Human immunodeficiency virus infectious disease 1 | 138
Hyperkyphosis 1 | 111
Hypokalemia 1 | 52
Hypokalemic periodic paralysis 1 | 11
Hypotrophic midface 1 | 105
Increased calcium level in kidney 1 | 21
Inflammatory Bowel Diseases 1 | 35
Juvenile rheumatoid arthritis 1 | 111
Kyphosis deformity of spine 1 | 114
Metabolic acidosis 1 | 90
Microdontia (disorder) 1 | 59
Midface retrusion 1 | 105
Osteopenia 1 | 99
Osteopetrosis autosomal recessive 1 1 | 2
Osteopetrosis, Autosomal Recessive 1 1 | 2
Pathological fracture 1 | 20
Progressive microcephaly 1 | 32
Rough hair texture 1 | 31
Sickle Cell Anemia 1 | 53
Small midface 1 | 105
Typhoid fever 1 | 22

Tissue

Blood and immune system 14 | 16,909
Digestive Tract 14 | 17,369
Endocrine System 14 | 18,159
Female tissues 14 | 17,400
Male tissues 14 | 17,142
Nervous System 14 | 16,725
Respiratory system 14 | 16,393
Skin and soft tissues 14 | 17,230
Urinary Tract 14 | 16,678
Cardiovascular System 13 | 15,192
Liver and Pancreas 13 | 16,750

Target Family

Enzyme 10 | 4,145
Non-IDG 2 | 12,091
Ion Channel 1 | 344
Transporter 1 | 473

GO Process

vacuolar acidification 14 | 14
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
DmX-like protein 1 DMXL1 Tdark Non-IDG -2.50063 311.1 13
V-type proton ATPase 116 kDa subunit a isoform 4 ATP6V0A4 Tbio Enzyme -2.84949 692.2 90
Natural resistance-associated macrophage protein 1 SLC11A1 Tbio Transporter -2.77524 629.3 129
DmX-like protein 2 DMXL2 Tbio Non-IDG -0.92783 9.34 16
V-type proton ATPase 21 kDa proteolipid subunit ATP6V0B Tbio Enzyme -0.96261 10.7 81
V-type proton ATPase 116 kDa subunit a isoform 3 TCIRG1 Tbio Enzyme -1.92345 93.5 63
V-type proton ATPase subunit d 2 ATP6V0D2 Tbio Enzyme -1.17065 12.0 74
V-type proton ATPase subunit H ATP6V1H Tbio Enzyme -1.26664 18.3 119
Chloride intracellular channel protein 4 CLIC4 Tbio Ion Channel -1.81713 70.5 221
V-type proton ATPase subunit e 2 ATP6V0E2 Tdark Enzyme 0.18 0.40 24