Development Level

Tchem 2 | 1,598

IMPC Phenotype

abnormal embryo size 1 | 220
abnormal heart morphology 1 | 162
abnormal seminal vesicle morph... 1 | 114
abnormal sensory capabilities-... 1 | 8
decreased lymphocyte cell numb... 1 | 83
edema 1 | 59
enlarged heart 1 | 210
enlarged seminal vesicle 1 | 10
hydrometra 1 | 53
increased monocyte cell number 1 | 63
microphthalmia 1 | 26
preweaning lethality, incomple... 1 | 499
small superior vagus ganglion 1 | 74

Disease

Carcinoma 2 | 11,493
Major Depressive Disorder 2 | 301
Pellagra 2 | 26
Unipolar Depression 2 | 250
breast carcinoma 2 | 1,638
cutaneous lupus erythematosus 2 | 1,057
ductal carcinoma in situ 2 | 1,745
invasive ductal carcinoma 2 | 2,951
malignant mesothelioma 2 | 3,232
ovarian cancer 2 | 8,520
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
primary Sjogren syndrome 2 | 735
psoriasis 2 | 6,694
Abnormal urinary amino-acid findings 1 | 38
Abnormality of the musculature 1 | 16
Abnormality of the respiratory system 1 | 4
Aminoaciduria 1 | 38
Amyotrophic lateral sclerosis 1 | 451
Astrocytoma, Pilocytic 1 | 3,081
Atopic dermatitis 1 | 952
Autistic Disorder 1 | 364
Autosomal recessive predisposition 1 | 1,442
Bipolar Disorder 1 | 666
Breast cancer 1 | 3,578
Cognitive delay 1 | 608
Comatose 1 | 56
Congenital deafness 1 | 185
Deafness 1 | 198
Depressed mood 1 | 17
Dull intelligence 1 | 645
Elevated heart rate 1 | 25
Gilles de la Tourette syndrome 1 | 47
Global developmental delay 1 | 608
Hearing Loss, Partial 1 | 185
Hydroxykynureninuria 1 | 1
Hypotension 1 | 82
Inflammation 1 | 120
Intellectual disability 1 | 1,016
Liver Cirrhosis, Experimental 1 | 769
Low intelligence 1 | 645
Mental Retardation 1 | 645
Mental and motor retardation 1 | 608
Mental deficiency 1 | 645
Metabolic acidosis 1 | 90
Muscle Hypertonia 1 | 88
Neurodegenerative Diseases 1 | 38
Neurodegenerative Disorders 1 | 79
Nonorganic psychosis 1 | 84
Nonprogressive encephalopathy 1 | 1
Photosensitivity disease 1 | 1
Poor school performance 1 | 645
Porphyria 1 | 10
Psychotic Disorders 1 | 151
Renal tubular disorder 1 | 12
SCHIZOPHRENIA 1 (disorder) 1 | 1
Schizophrenia 1 | 1,160
Starvation 1 | 1
Tachycardia 1 | 43
Waldenstrons macroglobulinemia 1 | 765
active Crohn's disease 1 | 922
active ulcerative colitis 1 | 764
adrenocortical carcinoma 1 | 1,428
adult high grade glioma 1 | 3,801
astrocytic glioma 1 | 2,597
chronic rhinosinusitis 1 | 512
cystic fibrosis 1 | 1,696
gastric carcinoma 1 | 807
glioblastoma 1 | 5,792
head and neck cancer and chronic obstructive pulmonary disease 1 | 239
hearing impairment 1 | 199
interstitial cystitis 1 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 1 | 3,291
lung adenocarcinoma 1 | 2,716
lung cancer 1 | 4,740
lung carcinoma 1 | 2,843
medulloblastoma 1 | 720
mucosa-associated lymphoid tissue lymphoma 1 | 484
non-small cell lung cancer 1 | 2,890
oligodendroglioma 1 | 2,850
pancreatic cancer 1 | 2,398
periodontitis 1 | 293
pituitary cancer 1 | 1,972
posterior fossa group A ependymoma 1 | 468
primitive neuroectodermal tumor 1 | 3,035
spina bifida 1 | 1,074
tuberculosis 1 | 2,010
ulcerative colitis 1 | 1,819

Tissue

Blood and immune system 2 | 16,909
Digestive Tract 2 | 17,369
Endocrine System 2 | 18,159
Female tissues 2 | 17,400
Liver and Pancreas 2 | 16,750
Male tissues 2 | 17,142
Nervous System 2 | 16,725
Respiratory system 2 | 16,393
Skin and soft tissues 2 | 17,230
Urinary Tract 2 | 16,678
Cardiovascular System 1 | 15,192

Target Family

Enzyme 2 | 4,145

GO Process

tryptophan catabolic process t... 2 | 2
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Kynureninase KYNU Tchem Enzyme -1.61116 39.2 173
Tryptophan 2,3-dioxygenase TDO2 Tchem Enzyme -2.89113 773.6 193