Development Level

Tbio 15 | 11,178
Tchem 10 | 1,885

IMPC Phenotype

decreased circulating glucose ... 2 | 126
decreased vertical activity 2 | 208
increased circulating alkaline... 2 | 122
increased circulating choleste... 2 | 66
increased circulating triglyce... 2 | 42
abnormal bone structure 1 | 187
abnormal kidney morphology 1 | 65
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal seminal vesicle morph... 1 | 114
abnormal tooth morphology 1 | 24
absent optic nerve 1 | 2
cardiovascular system phenotyp... 1 | 36
decreased bone mineral density 1 | 126
decreased cardiac muscle contr... 1 | 11
decreased circulating HDL chol... 1 | 68
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased heart rate 1 | 18
decreased heart weight 1 | 27
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
decreased total body fat amoun... 1 | 207
enlarged heart 1 | 210
enlarged spleen 1 | 41
impaired glucose tolerance 1 | 75
increased circulating LDL chol... 1 | 13
increased circulating bilirubi... 1 | 16
increased circulating free fat... 1 | 20
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 36
increased or absent threshold ... 1 | 101
increased red blood cell distr... 1 | 34
increased total body fat amoun... 1 | 134
increased total retina thickne... 1 | 4
persistence of hyaloid vascula... 1 | 33
prolonged PQ interval 1 | 5
prolonged QT interval 1 | 38

Disease

Atherosclerosis 15 | 276
Carcinoma 15 | 11,192
Lipid metabolism disorder 14 | 111
diabetes mellitus 14 | 1,683
Coronary artery disease 12 | 253
Obesity 12 | 655
invasive ductal carcinoma 10 | 2,867
psoriasis 10 | 6,514
medulloblastoma, large-cell 9 | 6,086
osteosarcoma 9 | 7,766
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,911
Cardiovascular system disease 8 | 240
ductal carcinoma in situ 8 | 1,686
ovarian cancer 8 | 8,297
malignant mesothelioma 7 | 3,135
Cancer 6 | 2,388
Hypercholesterolemia, Familial 6 | 22
Hyperlipoproteinemia Type II 6 | 12
Hypertension 6 | 372
Metabolic syndrome X 6 | 52
breast carcinoma 6 | 1,589
glioblastoma 6 | 5,635
Autosomal recessive predisposition 5 | 1,407
Chemical and Drug Induced Liver Injury 5 | 188
Hepatomegaly 5 | 280
Hyperlipidemia 5 | 43
Hypertriglyceridemia 5 | 17
Kidney disease 5 | 411
Schizophrenia 5 | 1,136
Type 2 diabetes mellitus 5 | 268
adult high grade glioma 5 | 3,701
group 3 medulloblastoma 5 | 4,002
primitive neuroectodermal tumor 5 | 2,957
ulcerative colitis 5 | 1,765
Acquired metabolic disease 4 | 329
Astrocytoma, Pilocytic 4 | 3,006
Breast cancer 4 | 3,469
Cardiovascular Diseases 4 | 57
Drug Eruptions 4 | 17
Dyslipidemias 4 | 27
Familial hyperlipidemia 4 | 6
Hypercholesterolemia 4 | 43
Hyperglycemia 4 | 134
Hyperlipidemias 4 | 17
Hypertensive disease 4 | 278
Liver Cirrhosis, Experimental 4 | 733
Pancreatitis 4 | 118
Serum cholesterol raised 4 | 22
Splenomegaly 4 | 186
Vascular disease 4 | 294
atypical teratoid / rhabdoid tumor 4 | 4,971
fibroadenoma 4 | 538
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,204
lung cancer 4 | 4,607
subependymal giant cell astrocytoma 4 | 2,230
tuberculosis 4 | 1,963
Age related macular degeneration 3 | 71
Atopic dermatitis 3 | 915
Cerebrovascular disease 3 | 223
Cholesteryl Ester Transfer Protein Deficiency 3 | 3
Diabetes Mellitus, Non-Insulin-Dependent 3 | 140
Diabetes Mellitus, Type 2 3 | 136
Eruptive xanthoma 3 | 3
Fatty liver disease 3 | 102
Heart disease 3 | 288
Hyperinsulinism 3 | 128
Hyperlipoproteinemias 3 | 5
Hypertriglyceridemia result 3 | 35
Hypotriglyceridaemia 3 | 3
Kidney Failure 3 | 108
Liver disease 3 | 227
Lung Neoplasms 3 | 217
Macular degeneration 3 | 64
Pediatric Obesity 3 | 4
Pick disease 3 | 1,856
Proteinuria 3 | 143
esophageal adenocarcinoma 3 | 696
gastric carcinoma 3 | 781
interstitial cystitis 3 | 2,237
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,872
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,902
lung adenocarcinoma 3 | 2,627
nephrosclerosis 3 | 314
non-small cell lung cancer 3 | 2,799
oligodendroglioma 3 | 2,768
spina bifida 3 | 1,053
Alzheimer's disease 2 | 640
Arthritis 2 | 276
Cholestasis 2 | 154
Cutis Laxa 2 | 39
Depressive disorder 2 | 401
Mental Depression 2 | 325
Polycystic ovary syndrome 2 | 348
Seizures 2 | 584
Waldenstrons macroglobulinemia 2 | 742
active Crohn's disease 2 | 882
acute quadriplegic myopathy 2 | 1,133
adrenocortical carcinoma 2 | 1,385
nasopharyngeal carcinoma 2 | 1,024
pediatric high grade glioma 2 | 1,035

Tissue

Digestive Tract 25 | 17,369
Endocrine System 24 | 18,159
Liver and Pancreas 24 | 16,750
Female tissues 23 | 17,400
Skin and soft tissues 23 | 17,230
Urinary Tract 23 | 16,678
Blood and immune system 22 | 16,909
Male tissues 22 | 17,142
Respiratory system 21 | 16,393
Nervous System 20 | 16,725
Cardiovascular System 19 | 15,192

Target Family

Non-IDG 16 | 12,091
Enzyme 5 | 4,145
Nuclear Receptor 3 | 48
Transcription Factor 1 | 1,400

GO Process

triglyceride homeostasis 25 | 25
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Acyl-coenzyme A synthetase ACSM2A, mitochondrial ACSM2A Tbio Enzyme -2.11752 121.7 60
Carbohydrate-responsive element-binding protein MLXIPL Tbio Transcription Factor -2.29554 206.7 235
Lipoprotein lipase LPL Tchem Enzyme -3.09646 876.3 338
Scavenger receptor class B member 1 SCARB1 Tchem Non-IDG -2.93920 915.7 378
Mediator of RNA polymerase II transcription subunit 13 MED13 Tbio Enzyme -1.52250 26.0 53
Apolipoprotein A-V APOA5 Tbio Non-IDG -2.58826 425.0 481
Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 GPIHBP1 Tbio Non-IDG -1.82315 79.6 104
Sestrin-2 SESN2 Tbio Non-IDG -1.88129 92.6 176
Cholesteryl ester transfer protein CETP Tchem Non-IDG -3.20658 1755.9 264
Apolipoprotein A-I APOA1 Tchem Non-IDG -3.62534 3592.8 1151