Development Level

Tbio 16 | 10,625
Tchem 10 | 1,890

IMPC Term

increased circulating alkaline... 2 | 119
increased circulating choleste... 2 | 53
increased circulating triglyce... 2 | 24
abnormal lens morphology 1 | 73
abnormal retina morphology 1 | 100
abnormal tooth morphology 1 | 24
absent optic nerve 1 | 1
cardiovascular system phenotyp... 1 | 35
decreased cardiac muscle contr... 1 | 5
decreased circulating HDL chol... 1 | 77
decreased circulating chloride... 1 | 32
decreased circulating glucose ... 1 | 121
decreased circulating serum al... 1 | 79
decreased circulating sodium l... 1 | 18
decreased heart rate 1 | 10
decreased heart weight 1 | 44
enlarged heart 1 | 111
enlarged spleen 1 | 26
impaired glucose tolerance 1 | 52
increased CD4-positive, CD25-p... 1 | 1
increased NK T cell number 1 | 11
increased circulating HDL chol... 1 | 63
increased circulating LDL chol... 1 | 15
increased circulating bilirubi... 1 | 16
increased circulating free fat... 1 | 17
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 37
increased mean corpuscular hem... 1 | 25
preweaning lethality, incomple... 1 | 260

Disease

Lipid metabolism disorder 14 | 102
diabetes mellitus 14 | 1,663
Atherosclerosis 13 | 275
Metabolic syndrome X 13 | 155
Coronary artery disease 11 | 240
Obesity 10 | 616
invasive ductal carcinoma 10 | 2,950
psoriasis 10 | 6,685
medulloblastoma, large-cell 9 | 6,234
osteosarcoma 9 | 7,933
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,795
Cardiovascular system disease 8 | 194
ductal carcinoma in situ 8 | 1,745
ovarian cancer 8 | 8,492
Hypercholesterolemia, Familial 6 | 18
breast carcinoma 6 | 1,614
glioblastoma 6 | 5,572
malignant mesothelioma 6 | 3,163
Cancer 5 | 2,346
Cardiovascular Diseases 5 | 50
Peripheral Neuropathy 5 | 303
Type 2 diabetes mellitus 5 | 192
primitive neuroectodermal tumor 5 | 3,031
ulcerative colitis 5 | 2,087
Breast cancer 4 | 3,099
Diabetes Mellitus, Non-Insulin-Dependent 4 | 161
Drug Eruptions 4 | 18
Drug-Induced Liver Injury 4 | 118
Familial hyperlipidemia 4 | 6
Hyperglycemia 4 | 120
Hyperlipidemia 4 | 25
Hyperlipoproteinemias 4 | 6
Hypertensive disease 4 | 193
Hypertriglyceridemia 4 | 18
Kidney disease 4 | 397
Pancreatitis 4 | 97
Vascular disease 4 | 281
adult high grade glioma 4 | 2,148
fibroadenoma 4 | 557
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,289
medulloblastoma 4 | 1,524
pilocytic astrocytoma 4 | 3,086
subependymal giant cell astrocytoma 4 | 2,287
Acquired metabolic disease 3 | 267
Age related macular degeneration 3 | 84
Atopic dermatitis 3 | 944
Coronary heart disease 3 | 59
Dyslipidemias 3 | 17
Heart disease 3 | 279
Hyperinsulinism 3 | 63
Hyperlipoproteinemia Type V 3 | 4
Hypertension 3 | 293
Liver disease 3 | 219
Lung Neoplasms 3 | 171
Pick disease 3 | 1,893
atypical teratoid / rhabdoid tumor 3 | 4,369
esophageal adenocarcinoma 3 | 737
gastric carcinoma 3 | 832
interstitial cystitis 3 | 2,299
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,988
lung adenocarcinoma 3 | 2,714
lung cancer 3 | 4,473
nephrosclerosis 3 | 329
non-small cell lung cancer 3 | 2,798
oligodendroglioma 3 | 2,849
pediatric high grade glioma 3 | 2,712
spina bifida 3 | 1,064
tuberculosis 3 | 1,563
Adenocarcinoma 2 | 115
Alzheimer's disease 2 | 644
Animal Mammary Neoplasms 2 | 136
Arthritis 2 | 248
Cerebrovascular disease 2 | 231
Diabetes Mellitus, Noninsulin-Dependent 2 | 31
Fatty liver disease 2 | 86
Hepatitis C 2 | 90
Hypercholesterolemia 2 | 27
Hypoglycemia 2 | 81
Leishmaniasis 2 | 49
Liver carcinoma 2 | 217
Macular degeneration 2 | 44
Mammary Neoplasms, Experimental 2 | 150
Neoplasm Metastasis 2 | 138
Prostatic Neoplasms 2 | 471
Schizophrenia 2 | 503
Stomach Neoplasms 2 | 282
Waldenstrons macroglobulinemia 2 | 765
active Crohn's disease 2 | 918
active ulcerative colitis 2 | 477
acute quadriplegic myopathy 2 | 1,157
adrenocortical carcinoma 2 | 1,427
atypical teratoid/rhabdoid tumor 2 | 1,095
cutaneous lupus erythematosus 2 | 1,056
dermatomyositis 2 | 967
head and neck cancer and chronic obstructive pulmonary disease 2 | 237
juvenile dermatomyositis 2 | 1,189
lung carcinoma 2 | 2,844
mucosa-associated lymphoid tissue lymphoma 2 | 480
nasopharyngeal carcinoma 2 | 1,056

Tissue

Blood and immune system 25 | 17,995
Digestive Tract 25 | 18,473
Endocrine System 25 | 18,512
Nervous System 25 | 18,561
Skin and soft tissues 25 | 18,115
Urinary Tract 25 | 18,444
Cardiovascular System 24 | 17,958
Female tissues 24 | 18,647
Liver and Pancreas 24 | 18,136
Male tissues 23 | 17,969
Respiratory system 23 | 17,484

Target Family

Non-IDG 17 | 11,969
Enzyme 5 | 4,146
Nuclear Receptor 3 | 48
Transcription Factor 1 | 1,400

GO Process

triglyceride homeostasis 26 | 26
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Mediator of RNA polymerase II transcription subunit 13 MED13 Tbio Enzyme -1.45091 21.4 49
Angiopoietin-related protein 4 ANGPTL4 Tbio Non-IDG -2.41477 298.0 270
Angiopoietin-related protein 3 ANGPTL3 Tbio Non-IDG -1.90212 87.6 323
Scavenger receptor class B member 1 SCARB1 Tchem Non-IDG -2.90915 869.1 327
Hepatocyte nuclear factor 4-alpha HNF4A Tchem Nuclear Receptor -3.17798 1303.8 610
Melanoma inhibitory activity protein 2 CTAGE5 Tbio Non-IDG -0.47712 0.00000 79
Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 GPIHBP1 Tbio Non-IDG -1.76802 68.9 90
Apolipoprotein A-V APOA5 Tbio Non-IDG -2.55941 400.3 366
Apolipoprotein E APOE Tbio Non-IDG -4.15802 15380.4 788
Apolipoprotein C-III APOC3 Tbio Non-IDG -2.91329 836.7 239