Development Level

Tbio 16 | 10,625
Tchem 10 | 1,890

IMPC Term

increased circulating alkaline... 2 | 119
increased circulating choleste... 2 | 53
increased circulating triglyce... 2 | 24
abnormal lens morphology 1 | 73
abnormal retina morphology 1 | 100
abnormal tooth morphology 1 | 24
absent optic nerve 1 | 1
cardiovascular system phenotyp... 1 | 35
decreased cardiac muscle contr... 1 | 5
decreased circulating HDL chol... 1 | 77
decreased circulating chloride... 1 | 32
decreased circulating glucose ... 1 | 121
decreased circulating serum al... 1 | 79
decreased circulating sodium l... 1 | 18
decreased heart rate 1 | 10
decreased heart weight 1 | 44
enlarged heart 1 | 111
enlarged spleen 1 | 26
impaired glucose tolerance 1 | 52
increased CD4-positive, CD25-p... 1 | 1
increased NK T cell number 1 | 11
increased circulating HDL chol... 1 | 63
increased circulating LDL chol... 1 | 15
increased circulating bilirubi... 1 | 16
increased circulating free fat... 1 | 17
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 37
increased mean corpuscular hem... 1 | 25
preweaning lethality, incomple... 1 | 260

Disease

Lipid metabolism disorder 14 | 102
diabetes mellitus 14 | 1,663
Atherosclerosis 13 | 275
Metabolic syndrome X 13 | 155
Coronary artery disease 11 | 240
Obesity 10 | 616
invasive ductal carcinoma 10 | 2,950
psoriasis 10 | 6,685
medulloblastoma, large-cell 9 | 6,234
osteosarcoma 9 | 7,933
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,795
Cardiovascular system disease 8 | 194
ductal carcinoma in situ 8 | 1,745
ovarian cancer 8 | 8,484
Hypercholesterolemia, Familial 6 | 16
breast carcinoma 6 | 1,614
glioblastoma 6 | 5,572
malignant mesothelioma 6 | 3,162
Cancer 5 | 2,346
Cardiovascular Diseases 5 | 50
Peripheral Neuropathy 5 | 303
Type 2 diabetes mellitus 5 | 189
primitive neuroectodermal tumor 5 | 3,031
ulcerative colitis 5 | 2,087
Breast cancer 4 | 3,094
Drug Eruptions 4 | 18
Drug-Induced Liver Injury 4 | 118
Familial hyperlipidemia 4 | 6
Hyperglycemia 4 | 120
Hyperlipidemia 4 | 25
Hyperlipoproteinemias 4 | 6
Hypertensive disease 4 | 193
Hypertriglyceridemia 4 | 18
Kidney disease 4 | 396
Pancreatitis 4 | 97
Vascular disease 4 | 281
adult high grade glioma 4 | 2,148
fibroadenoma 4 | 557
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,289
medulloblastoma 4 | 1,524
pilocytic astrocytoma 4 | 3,086
subependymal giant cell astrocytoma 4 | 2,287
Acquired metabolic disease 3 | 267
Age related macular degeneration 3 | 84
Atopic dermatitis 3 | 944
Coronary heart disease 3 | 59
Diabetes Mellitus, Non-Insulin-Dependent 3 | 157
Dyslipidemias 3 | 17
Heart disease 3 | 279
Hyperinsulinism 3 | 63
Hyperlipoproteinemia Type V 3 | 4
Hypertension 3 | 287
Liver disease 3 | 219
Lung Neoplasms 3 | 171
Pick disease 3 | 1,893
atypical teratoid / rhabdoid tumor 3 | 4,369
esophageal adenocarcinoma 3 | 737
gastric carcinoma 3 | 832
interstitial cystitis 3 | 2,299
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,988
lung adenocarcinoma 3 | 2,713
lung cancer 3 | 4,466
nephrosclerosis 3 | 329
non-small cell lung cancer 3 | 2,798
oligodendroglioma 3 | 2,849
pediatric high grade glioma 3 | 2,712
spina bifida 3 | 1,064
tuberculosis 3 | 1,557
Adenocarcinoma 2 | 115
Alzheimer's disease 2 | 644
Animal Mammary Neoplasms 2 | 136
Arthritis 2 | 248
Asthma 2 | 349
Cerebrovascular disease 2 | 231
Fatty liver disease 2 | 84
Hepatitis C 2 | 90
Hypercholesterolemia 2 | 27
Hypoglycemia 2 | 81
Leishmaniasis 2 | 49
Liver carcinoma 2 | 217
Macular degeneration 2 | 41
Mammary Neoplasms, Experimental 2 | 150
Neoplasm Metastasis 2 | 138
Prostatic Neoplasms 2 | 471
Schizophrenia 2 | 501
Stomach Neoplasms 2 | 282
Waldenstrons macroglobulinemia 2 | 765
active Crohn's disease 2 | 918
active ulcerative colitis 2 | 477
acute quadriplegic myopathy 2 | 1,157
adrenocortical carcinoma 2 | 1,427
atypical teratoid/rhabdoid tumor 2 | 1,095
cutaneous lupus erythematosus 2 | 1,056
dermatomyositis 2 | 933
head and neck cancer and chronic obstructive pulmonary disease 2 | 237
juvenile dermatomyositis 2 | 1,189
lung carcinoma 2 | 2,844
mucosa-associated lymphoid tissue lymphoma 2 | 480
nasopharyngeal carcinoma 2 | 1,056

Tissue

Blood and immune system 25 | 17,995
Digestive Tract 25 | 18,473
Endocrine System 25 | 18,512
Nervous System 25 | 18,561
Skin and soft tissues 25 | 18,115
Urinary Tract 25 | 18,444
Cardiovascular System 24 | 17,958
Female tissues 24 | 18,647
Liver and Pancreas 24 | 18,136
Male tissues 23 | 17,969
Respiratory system 23 | 17,484

Target Family

Non-IDG 17 | 11,971
Enzyme 5 | 4,146
Nuclear Receptor 3 | 48
Transcription Factor 1 | 1,400

GO Process

triglyceride homeostasis 26 | 26
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Apolipoprotein E APOE Tbio Non-IDG -4.17470 15380.4 788
Apolipoprotein A-I APOA1 Tchem Non-IDG -3.60439 3516.7 901
Apolipoprotein C-II APOC2 Tbio Non-IDG -2.49982 337.4 18
Apolipoprotein C-III APOC3 Tbio Non-IDG -2.90374 836.7 239
Nuclear receptor ROR-alpha RORA Tchem Nuclear Receptor -2.17386 139.2 340
Sestrin-2 SESN2 Tbio Non-IDG -1.73062 73.0 151
Apolipoprotein A-V APOA5 Tbio Non-IDG -2.54064 400.3 366
Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 GPIHBP1 Tbio Non-IDG -1.74068 68.9 90
Hepatocyte nuclear factor 4-alpha HNF4A Tchem Nuclear Receptor -3.16372 1303.8 610
Angiopoietin-related protein 4 ANGPTL4 Tbio Non-IDG -2.36340 298.0 270