Development Level

Tbio 3 | 11,445
Tchem 1 | 1,598

IMPC Phenotype

preweaning lethality, complete... 1 | 979

Disease

Carcinoma 4 | 11,493
Astrocytoma, Pilocytic 3 | 3,081
invasive ductal carcinoma 3 | 2,951
lung adenocarcinoma 3 | 2,716
lung cancer 3 | 4,740
lung carcinoma 3 | 2,843
malignant mesothelioma 3 | 3,232
ovarian cancer 3 | 8,520
Breast cancer 2 | 3,578
Cancer 2 | 2,499
adult high grade glioma 2 | 3,801
atypical teratoid / rhabdoid tumor 2 | 5,112
glioblastoma 2 | 5,792
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
nasopharyngeal carcinoma 2 | 1,058
non-small cell lung cancer 2 | 2,890
osteosarcoma 2 | 7,950
Abnormality of the cerebrum 1 | 3
Abnormality of the voice 1 | 46
Absent auditory canals 1 | 23
Absent external auditory canals 1 | 23
Anosmia 1 | 22
Anterior hypopituitarism 1 | 18
Atresia of the external auditory canal 1 | 23
Atretic auditory canal 1 | 23
Autosomal dominant nonsyndromic deafness 10 1 | 4
Autosomal dominant nonsyndromic deafness 23 1 | 3
Bone disease 1 | 10
Branchioma 1 | 3
Branchiootic syndrome 1 | 12
Branchiootorenal syndrome 1 | 8
Cholesteatoma 1 | 16
Cleft uvula 1 | 27
Conductive hearing loss 1 | 123
Congenital Abnormalities 1 | 11
Congenital Abnormality 1 | 11
Congenital deafness 1 | 185
Congenital hypoplasia of breast 1 | 25
Craniofacial Abnormalities 1 | 151
Deafness 1 | 198
Decreased bone mineral density Z score 1 | 31
Decreased fertility 1 | 33
Decreased size of teeth 1 | 62
Decreased width of tooth 1 | 59
Deep overbite 1 | 4
Delayed Puberty 1 | 97
Endometrial Neoplasms 1 | 55
Erectile abnormalities 1 | 16
Euthyroid Goiter 1 | 3
Eye and adnexa disease 1 | 18
Frontotemporal dementia 1 | 51
Hearing Loss, Mixed Conductive-Sensorineural 1 | 12
Hearing Loss, Partial 1 | 185
Highly variable severity 1 | 157
Hip Dislocation, Congenital 1 | 48
Hypogonadism, Isolated Hypogonadotropic 1 | 71
Hypogonadotropic hypogonadism 1 | 89
Hypoplastic cochlea 1 | 6
Hypothalamic gonadotropin-releasing hormone deficiency 1 | 14
Incomplete partition of the cochlea type II 1 | 3
Kallmann syndrome 1 | 33
Klinefelter's syndrome 1 | 56
Liver diseases 1 | 87
Malformed ossicles 1 | 3
Malformed pinnae 1 | 37
Microdontia (disorder) 1 | 59
Middle ear malformations 1 | 5
Mondini malformation 1 | 3
Myocardial Infarction 1 | 151
Narrow face 1 | 54
Narrowing of ear canal 1 | 13
Neurodegenerative disease 1 | 414
Nonsyndromic deafness 1 | 142
Overbite 1 | 4
Posterior lingual occlusion of mandibular teeth 1 | 4
Posterior polar cataract 1 | 6
Preauricular Fistulae, Congenital 1 | 27
Preauricular dimple 1 | 27
Preauricular sinus 1 | 27
Preauricular skin tag 1 | 19
Prion disease 1 | 16
RENAL ADYSPLASIA 1 | 25
Renal agenesis 1 | 29
Renal dysplasia 1 | 28
Renal hypoplasia/aplasia 1 | 7
Retinopathy of prematurity 1 | 22
Sense of smell impaired 1 | 21
Sensorineural Hearing Loss (disorder) 1 | 284
Skin tag on the posterior cheek 1 | 19
Small testicle 1 | 75
Stenosis of external auditory canal 1 | 13
Stenosis of nasolacrimal duct 1 | 4
Thin face 1 | 54
Townes-Brocks syndrome 1 | 15
Variable expressivity 1 | 157
Vesico-Ureteral Reflux 1 | 33
Wilms Tumor 1 | 28
atypical teratoid/rhabdoid tumor 1 | 357
hearing impairment 1 | 199
hereditary spastic paraplegia 1 | 318

Tissue

Blood and immune system 4 | 16,909
Digestive Tract 4 | 17,369
Endocrine System 4 | 18,159
Female tissues 4 | 17,400
Liver and Pancreas 4 | 16,750
Male tissues 4 | 17,142
Nervous System 4 | 16,725
Respiratory system 4 | 16,393
Skin and soft tissues 4 | 17,230
Urinary Tract 4 | 16,678
Cardiovascular System 3 | 15,192

Target Family

Non-IDG 2 | 12,091
Transcription Factor 2 | 1,400

GO Process

trigeminal ganglion developmen... 4 | 4
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Homeobox protein SIX4 SIX4 Tbio Transcription Factor -2.31722 197.8 141
Semaphorin-3A SEMA3A Tbio Non-IDG -2.70786 548.1 185
Neuropilin-1 NRP1 Tchem Non-IDG -2.71062 531.2 587
Homeobox protein SIX1 SIX1 Tbio Transcription Factor -2.64041 433.7 111