Development Level

Tbio 3 | 11,445

IMPC Phenotype

abnormal gait 1 | 69
increased circulating fructosa... 1 | 13
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28

Disease

Carcinoma 2 | 11,493
osteosarcoma 2 | 7,950
Adult Fanconi syndrome 1 | 12
Asymptomatic hyperammonemia 1 | 1
Autosomal recessive infantile hypercalcemia 1 | 2
Autosomal recessive predisposition 1 | 1,442
Bone Diseases, Developmental 1 | 27
Calcinosis 1 | 70
Cancer 1 | 2,499
Cardiomegaly 1 | 116
Down syndrome 1 | 499
Dull intelligence 1 | 645
Endomyocardial Fibrosis 1 | 13
FRTS1 1 | 2
Fanconi Renotubular Syndrome 2 1 | 1
Fanconi syndrome 1 | 14
Fetal Growth Retardation 1 | 189
Generalized aminoaciduria 1 | 9
Generalized dystonia 1 | 4
Generalized osteopenia 1 | 99
Glycosuria 1 | 29
Hyperammonemia 1 | 30
Hypercalcemia 1 | 59
Hypercalcemia, Infantile 1 | 3
Hypercalciuria 1 | 27
Hyperinsulinaemic hypoglycaemia 1 | 16
Hyperinsulinemic hypoglycemia 1 | 17
Hyperinsulinemic hypoglycemia, familial, 6 1 | 1
Hyperinsulinism 1 | 133
Hyperphosphatemia 1 | 32
Hyperphosphaturia 1 | 21
Hypochromic anemia 1 | 9
Hypoglycaemic seizure 1 | 10
Hypoglycemia 1 | 152
Hypoglycemic coma 1 | 10
Hypophosphatemia 1 | 40
Increased serum bone-specific alkaline phosphatase 1 | 4
Increased susceptibility to fractures 1 | 21
Intellectual disability 1 | 1,016
Kidney Failure 1 | 111
Kidney disease 1 | 430
Low intelligence 1 | 645
Mental Retardation 1 | 645
Mental deficiency 1 | 645
Multiple myeloma 1 | 1,332
Muscle Weakness 1 | 170
NEPHROLITHIASIS/OSTEOPOROSIS, HYPOPHOSPHATEMIC, 1 1 | 1
Nephrolithiasis 1 | 56
Nephrolithiasis-Osteoporosis, Hypophosphatemic, 1 1 | 1
Obesity 1 | 678
Osteomalacia 1 | 35
Osteopenia 1 | 99
Osteoporosis 1 | 363
Poor school performance 1 | 645
Proximal tubulopathy 1 | 9
Pulmonary alveolar microlithiasis 1 | 4
Renal Insufficiency 1 | 90
Renal failure in adulthood 1 | 76
Renal phosphate wasting 1 | 7
Rickets 1 | 49
Short stature 1 | 531
Urine phosphorous concentration above normal 1 | 21
adult high grade glioma 1 | 3,801
atypical teratoid / rhabdoid tumor 1 | 5,112
diabetes mellitus 1 | 1,728
gastric carcinoma 1 | 807
glioblastoma 1 | 5,792
group 3 medulloblastoma 1 | 4,104
hypophosphatemic nephrolithiasis/osteoporosis 1 1 | 1
medulloblastoma, large-cell 1 | 6,241
nephrosclerosis 1 | 333
ovarian cancer 1 | 8,520
pancreatic ductal adenocarcinoma liver metastasis 1 | 1,962
primitive neuroectodermal tumor 1 | 3,035
psoriasis 1 | 6,694
subependymal giant cell astrocytoma 1 | 2,287

Tissue

Digestive Tract 3 | 17,369
Liver and Pancreas 3 | 16,750
Male tissues 3 | 17,142
Nervous System 3 | 16,725
Skin and soft tissues 3 | 17,230
Urinary Tract 3 | 16,678
Blood and immune system 2 | 16,909
Cardiovascular System 2 | 15,192
Endocrine System 2 | 18,159
Female tissues 2 | 17,400
Respiratory system 2 | 16,393

Target Family

Enzyme 1 | 4,145
Epigenetic 1 | 242
Transporter 1 | 473

GO Process

tricarboxylic acid metabolic p... 3 | 3
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Glutamate dehydrogenase 1, mitochondrial GLUD1 Tbio Enzyme -2.39787 257.7 148
Sodium-dependent phosphate transport protein 2A SLC34A1 Tbio Transporter -1.98345 87.1 65
NAD-dependent protein lipoamidase sirtuin-4, mitochondrial SIRT4 Tbio Epigenetic -2.14139 133.9 254