Development Level

Tbio 134 | 11,178
Tchem 55 | 1,885
Tclin 41 | 612
Tdark 25 | 6,569

Collection

Ion Channel: IDG Consortium (T... 15 | 99

IMPC Phenotype

preweaning lethality, incomple... 10 | 499
preweaning lethality, complete... 7 | 979
abnormal behavior 5 | 298
decreased body weight 5 | 161
decreased vertical activity 5 | 208
enlarged heart 5 | 210
increased circulating alkaline... 5 | 122
abnormal heart morphology 4 | 162
decreased bone mineral density 4 | 126
increased startle reflex 4 | 112
abnormal embryo size 3 | 220
abnormal epididymis morphology 3 | 42
abnormal retina morphology 3 | 71
abnormal seminal vesicle morph... 3 | 114
decreased circulating HDL chol... 3 | 68
decreased circulating choleste... 3 | 93
decreased grip strength 3 | 116
decreased lymphocyte cell numb... 3 | 83
decreased mean corpuscular hem... 3 | 50
decreased mean corpuscular vol... 3 | 79
embryonic lethality prior to t... 3 | 278
enlarged epididymis 3 | 31
impaired glucose tolerance 3 | 75
increased blood urea nitrogen ... 3 | 48
increased mean corpuscular hem... 3 | 96
increased total body fat amoun... 3 | 134
small superior vagus ganglion 3 | 74
abnormal coat-hair pigmentatio... 2 | 64
abnormal gait 2 | 69
abnormal lens morphology 2 | 81
abnormal skin morphology 2 | 50
abnormal sleep behavior 2 | 70
abnormal spleen morphology 2 | 55
abnormal vibrissa morphology 2 | 25
cataract 2 | 92
decreased body length 2 | 101
decreased circulating LDL chol... 2 | 38
decreased circulating alkaline... 2 | 46
decreased circulating calcium ... 2 | 36
decreased circulating chloride... 2 | 30
decreased circulating creatini... 2 | 39
decreased circulating fructosa... 2 | 30
decreased circulating iron lev... 2 | 32
decreased erythrocyte cell num... 2 | 62
decreased fasted circulating g... 2 | 65
decreased hemoglobin content 2 | 68
decreased lean body mass 2 | 135
decreased leukocyte cell numbe... 2 | 73
decreased prepulse inhibition 2 | 82
edema 2 | 59
embryonic growth retardation 2 | 106
embryonic lethality prior to o... 2 | 239
hydrometra 2 | 53
hyperactivity 2 | 148
improved glucose tolerance 2 | 79
increased anti-nuclear antigen... 2 | 19
increased circulating HDL chol... 2 | 80
increased circulating amylase ... 2 | 25
increased circulating calcium ... 2 | 34
increased circulating creatini... 2 | 38
increased circulating serum al... 2 | 22
increased heart weight 2 | 62
increased mean platelet volume 2 | 45
increased monocyte cell number 2 | 63
limb grasping 2 | 41
small heart 2 | 10
small testis 2 | 58
abnormal embryo turning 1 | 31
abnormal head morphology 1 | 10
abnormal heart looping 1 | 5
abnormal lung morphology 1 | 26
abnormal neural tube closure 1 | 46
abnormal neural tube morpholog... 1 | 12
abnormal testis morphology 1 | 43
abnormal vocalization 1 | 21
absent vibrissae 1 | 12
decreased IgE level 1 | 6
decreased circulating amylase ... 1 | 28
decreased circulating creatine... 1 | 4
decreased circulating serum al... 1 | 82
decreased circulating triglyce... 1 | 79
decreased hematocrit 1 | 46
decreased neutrophil cell numb... 1 | 42
enlarged spleen 1 | 41
enlarged urinary bladder 1 | 8
increased body length 1 | 32
increased body weight 1 | 25
increased circulating bilirubi... 1 | 16
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating creatine... 1 | 5
increased circulating fructosa... 1 | 13
increased circulating total pr... 1 | 28
increased circulating triglyce... 1 | 42
increased exploration in new e... 1 | 8
increased lean body mass 1 | 172
prenatal lethality 1 | 28
thin ventricular wall 1 | 24
tremors 1 | 39
vertebral fusion 1 | 23

Disease

Carcinoma 169 | 11,192
psoriasis 112 | 6,514
ovarian cancer 109 | 8,297
medulloblastoma, large-cell 105 | 6,086
glioblastoma 102 | 5,635
osteosarcoma 100 | 7,766
atypical teratoid / rhabdoid tumor 90 | 4,971
ependymoma 77 | 4,559
group 3 medulloblastoma 73 | 4,002
adult high grade glioma 69 | 3,701
lung cancer 69 | 4,607
oligodendroglioma 67 | 2,768
primitive neuroectodermal tumor 62 | 2,957
Astrocytoma, Pilocytic 58 | 3,006
Breast cancer 58 | 3,469
Kidney cancer 55 | 2,548
astrocytic glioma 53 | 2,530
intraductal papillary-mucinous neoplasm (IPMN) 52 | 3,204
lung carcinoma 50 | 2,755
Autosomal recessive predisposition 49 | 1,407
malignant mesothelioma 49 | 3,135
Schizophrenia 47 | 1,136
Epilepsy 46 | 775
intraductal papillary-mucinous adenoma (IPMA) 45 | 2,872
intraductal papillary-mucinous carcinoma (IPMC) 45 | 2,902
subependymal giant cell astrocytoma 42 | 2,230
pituitary cancer 41 | 1,915
lung adenocarcinoma 38 | 2,627
pancreatic ductal adenocarcinoma liver metastasis 37 | 1,911
non-small cell lung cancer 35 | 2,799
Cancer 34 | 2,388
Pick disease 34 | 1,856
invasive ductal carcinoma 34 | 2,867
pancreatic cancer 34 | 2,322
ulcerative colitis 34 | 1,765
Bipolar Disorder 33 | 646
interstitial cystitis 33 | 2,237
tuberculosis 28 | 1,963
Intellectual disability 27 | 998
Liver Cirrhosis, Experimental 24 | 733
Rheumatoid arthritis 24 | 1,156
cystic fibrosis 24 | 1,629
astrocytoma 23 | 1,113
colon cancer 23 | 1,428
acute quadriplegic myopathy 22 | 1,133
Hypertensive disease 21 | 278
Seizures 21 | 584
adrenocortical carcinoma 21 | 1,385
ductal carcinoma in situ 21 | 1,686
Autistic Disorder 20 | 358
Dull intelligence 20 | 634
General anesthesia 20 | 53
Low intelligence 20 | 634
Mental Retardation 20 | 634
Mental deficiency 20 | 634
Poor school performance 20 | 634
diabetes mellitus 20 | 1,683
Alcoholic Intoxication, Chronic 19 | 283
Hypertension 19 | 372
active Crohn's disease 19 | 882
active ulcerative colitis 19 | 736
group 4 medulloblastoma 19 | 1,806
Cerebellar Ataxia 18 | 302
Depressive disorder 18 | 401
Muscle hypotonia 18 | 562
breast carcinoma 18 | 1,589
spina bifida 18 | 1,053
Infantile onset 17 | 236
Mental Depression 17 | 325
cutaneous lupus erythematosus 17 | 1,016
juvenile dermatomyositis 17 | 1,147
non primary Sjogren syndrome sicca 17 | 861
pediatric high grade glioma 17 | 1,035
Melanoma 16 | 689
Multiple myeloma 16 | 1,296
Cognitive delay 15 | 596
Colorectal Neoplasms 15 | 235
Duchenne muscular dystrophy 15 | 587
Global developmental delay 15 | 596
Liver cancer 15 | 589
Mental and motor retardation 15 | 596
Nystagmus 15 | 309
Obesity 15 | 655
Tonic-clonic epilepsy 15 | 47
gastric carcinoma 15 | 781
primary pancreatic ductal adenocarcinoma 15 | 1,071
Cataract 13 | 290
Diarrhea 13 | 245
Dysarthria 13 | 190
Failure to gain weight 13 | 359
Kidney disease 13 | 411
Pediatric failure to thrive 13 | 359
esophageal adenocarcinoma 13 | 696
medulloblastoma 13 | 702
Atopic dermatitis 12 | 915
Cholestasis 12 | 154
Neuropathy 12 | 254
dermatomyositis 12 | 941
progressive supranuclear palsy 12 | 656
Retinitis Pigmentosa 11 | 223

Tissue

Endocrine System 247 | 18,159
Digestive Tract 239 | 17,369
Male tissues 238 | 17,142
Skin and soft tissues 236 | 17,230
Nervous System 234 | 16,725
Female tissues 233 | 17,400
Urinary Tract 228 | 16,678
Blood and immune system 226 | 16,909
Liver and Pancreas 224 | 16,750
Respiratory system 211 | 16,393
Cardiovascular System 190 | 15,192

Target Family

Transporter 87 | 473
Non-IDG 83 | 12,091
Ion Channel 70 | 344
Enzyme 13 | 4,145
Nuclear Receptor 1 | 48
Transcription Factor 1 | 1,400

GO Process

transport 255 | 255
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Neuronatin NNAT Tbio Non-IDG -1.98217 101.3 38
Solute carrier family 12 member 3 SLC12A3 Tclin Transporter -2.82971 634.2 167
Solute carrier family 12 member 2 SLC12A2 Tclin Transporter -3.01974 1033.9 235
Gap junction beta-2 protein GJB2 Tbio Non-IDG -3.17642 1514.7 242
Aquaporin-4 AQP4 Tchem Non-IDG -3.33435 2159.1 358
Plasma membrane calcium-transporting ATPase 3 ATP2B3 Tbio Transporter -2.52332 332.0 52
P2X purinoceptor 3 P2RX3 Tchem Ion Channel -2.55623 360.2 162
ADP/ATP translocase 2 SLC25A5 Tbio Transporter -1.98936 91.6 65
Brain mitochondrial carrier protein 1 SLC25A14 Tbio Transporter -1.45184 29.0 51
Multidrug resistance-associated protein 6 ABCC6 Tchem Transporter -2.71911 547.1 100