Development Level

Tbio 106 | 11,445
Tdark 25 | 6,588
Tchem 14 | 1,598
Tclin 9 | 613

IMPC Phenotype

preweaning lethality, complete... 10 | 979
abnormal eye morphology 4 | 68
vertebral fusion 3 | 23
abnormal behavior 2 | 298
abnormal behavioral response t... 2 | 66
abnormal bone structure 2 | 187
abnormal coat appearance 2 | 31
abnormal cornea morphology 2 | 31
abnormal eye size 2 | 7
abnormal hair growth 2 | 10
abnormal lens morphology 2 | 81
abnormal lung morphology 2 | 26
cataract 2 | 92
decreased body weight 2 | 161
decreased caudal vertebrae num... 2 | 53
decreased circulating HDL chol... 2 | 68
decreased circulating choleste... 2 | 93
decreased circulating glucose ... 2 | 126
decreased circulating total pr... 2 | 49
decreased fasted circulating g... 2 | 65
decreased leukocyte cell numbe... 2 | 73
decreased mean corpuscular hem... 2 | 50
decreased total body fat amoun... 2 | 207
decreased vertical activity 2 | 208
impaired glucose tolerance 2 | 75
increased bone mineral density 2 | 72
increased lean body mass 2 | 172
increased mean corpuscular hem... 2 | 96
increased mean corpuscular vol... 2 | 92
limb grasping 2 | 41
abnormal coat-hair pigmentatio... 1 | 64
abnormal eye pigmentation 1 | 3
abnormal eyelid aperture 1 | 2
abnormal iris morphology 1 | 13
abnormal kidney morphology 1 | 65
abnormal response to new envir... 1 | 10
abnormal response to tactile s... 1 | 17
abnormal retina morphology 1 | 71
abnormal retinal vasculature m... 1 | 27
abnormal rib morphology 1 | 10
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal spleen morphology 1 | 55
abnormal tail morphology 1 | 25
abnormal vibrissa morphology 1 | 25
absent pinna reflex 1 | 23
anophthalmia 1 | 33
cardiovascular system phenotyp... 1 | 36
corneal opacity 1 | 32
corneal vascularization 1 | 6
decreased bone mineral content 1 | 151
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating alkaline... 1 | 46
decreased circulating aspartat... 1 | 34
decreased circulating fructosa... 1 | 30
decreased circulating serum al... 1 | 82
decreased grip strength 1 | 116
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular vol... 1 | 79
decreased mean platelet volume 1 | 25
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
edema 1 | 59
embryonic lethality prior to o... 1 | 239
enlarged lung 1 | 2
excessive tearing 1 | 2
hemorrhage 1 | 23
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired pupillary reflex 1 | 26
increased anti-nuclear antigen... 1 | 19
increased body weight 1 | 25
increased bone mineral content 1 | 108
increased circulating alkaline... 1 | 122
increased circulating bilirubi... 1 | 16
increased circulating fructosa... 1 | 13
increased circulating sodium l... 1 | 71
increased fasted circulating g... 1 | 76
increased grip strength 1 | 41
increased heart rate 1 | 23
increased heart rate variabili... 1 | 7
increased heart weight 1 | 62
increased kidney weight 1 | 6
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased prepulse inhibition 1 | 32
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
male infertility 1 | 123
narrow eye opening 1 | 12
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
small adrenal glands 1 | 16
thrombocytosis 1 | 27
trunk curl 1 | 16

Disease

Carcinoma 102 | 11,493
ovarian cancer 94 | 8,520
osteosarcoma 65 | 7,950
psoriasis 63 | 6,694
glioblastoma 54 | 5,792
lung cancer 54 | 4,740
medulloblastoma, large-cell 47 | 6,241
atypical teratoid / rhabdoid tumor 38 | 5,112
ependymoma 36 | 4,679
pancreatic ductal adenocarcinoma liver metastasis 35 | 1,962
Breast cancer 33 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 33 | 3,291
Multiple myeloma 32 | 1,332
intraductal papillary-mucinous adenoma (IPMA) 29 | 2,955
Astrocytoma, Pilocytic 28 | 3,081
malignant mesothelioma 28 | 3,232
Kidney cancer 27 | 2,613
adult high grade glioma 25 | 3,801
oligodendroglioma 25 | 2,850
interstitial cystitis 24 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 24 | 2,989
astrocytic glioma 23 | 2,597
lung carcinoma 23 | 2,843
non-small cell lung cancer 23 | 2,890
group 3 medulloblastoma 22 | 4,104
invasive ductal carcinoma 22 | 2,951
Cancer 21 | 2,499
Colorectal Neoplasms 21 | 243
pancreatic cancer 21 | 2,398
lung adenocarcinoma 20 | 2,716
Autosomal recessive predisposition 19 | 1,442
Pick disease 19 | 1,894
primitive neuroectodermal tumor 19 | 3,035
subependymal giant cell astrocytoma 19 | 2,287
cystic fibrosis 18 | 1,696
HIV Infections 16 | 102
tuberculosis 16 | 2,010
Rheumatoid arthritis 15 | 1,191
Waldenstrons macroglobulinemia 15 | 765
dermatomyositis 15 | 966
diabetes mellitus 14 | 1,728
Liver Cirrhosis, Experimental 13 | 769
astrocytoma 13 | 1,146
ductal carcinoma in situ 13 | 1,745
ulcerative colitis 12 | 1,819
Hepatomegaly 11 | 285
active ulcerative colitis 11 | 764
adrenocortical carcinoma 11 | 1,428
juvenile dermatomyositis 11 | 1,187
progressive supranuclear palsy 11 | 676
Neurodegenerative disease 10 | 414
Skin cancer 10 | 469
acute quadriplegic myopathy 10 | 1,158
non primary Sjogren syndrome sicca 10 | 891
pediatric high grade glioma 10 | 1,064
Alzheimer's disease 9 | 658
Failure to gain weight 9 | 365
Pediatric failure to thrive 9 | 365
active Crohn's disease 9 | 922
breast carcinoma 9 | 1,638
cutaneous lupus erythematosus 9 | 1,057
pituitary cancer 9 | 1,972
primary pancreatic ductal adenocarcinoma 9 | 1,109
Anemia 8 | 365
Cholestasis 8 | 155
Disease Progression 8 | 136
Epilepsy 8 | 792
Liver cancer 8 | 604
aldosterone-producing adenoma 8 | 665
colon cancer 8 | 1,478
gastric cancer 8 | 459
group 4 medulloblastoma 8 | 1,855
Duchenne muscular dystrophy 7 | 601
Intellectual disability 7 | 1,016
Seizures 7 | 596
medulloblastoma 7 | 720
Anteverted nostril 6 | 191
Diarrhea 6 | 253
Hypertension 6 | 396
Liver disease 6 | 237
Melanoma 6 | 711
Muscle Weakness 6 | 170
Neurogenic Muscular Atrophy 6 | 139
Neurogenic muscle atrophy, especially in the lower limbs 6 | 139
Neuropathy 6 | 261
Peripheral Neuropathy 6 | 134
Skeletal muscle atrophy 6 | 139
Tangier disease 6 | 10
acute myeloid leukemia 6 | 783
esophageal adenocarcinoma 6 | 737
muscle degeneration 6 | 139
posterior fossa group A ependymoma 6 | 468
primary Sjogren syndrome 6 | 735
Arthritis, Rheumatoid 5 | 174
Down syndrome 5 | 499
Endometriosis 5 | 540
Prostatic Neoplasms 5 | 495
Schizophrenia 5 | 1,160
fibroadenoma 5 | 559
mucosa-associated lymphoid tissue lymphoma 5 | 484

Tissue

Endocrine System 154 | 18,159
Female tissues 153 | 17,400
Digestive Tract 152 | 17,369
Nervous System 152 | 16,725
Male tissues 150 | 17,142
Skin and soft tissues 150 | 17,230
Urinary Tract 149 | 16,678
Blood and immune system 147 | 16,909
Liver and Pancreas 147 | 16,750
Respiratory system 145 | 16,393
Cardiovascular System 141 | 15,192

Target Family

Non-IDG 53 | 12,091
Transporter 52 | 473
Enzyme 47 | 4,145
Ion Channel 2 | 344

GO Process

transmembrane transport 154 | 154
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Proteasome activator complex subunit 2 PSME2 Tbio Non-IDG -1.47440 29.1 305
Feline leukemia virus subgroup C receptor-related protein 1 FLVCR1 Tbio Non-IDG -1.54460 33.8 139
Proteasome subunit beta type-10 PSMB10 Tchem Enzyme -1.88722 74.3 178
Choline transporter-like protein 1 SLC44A1 Tbio Transporter -1.60796 43.9 212
Derlin-1 DERL1 Tbio Non-IDG -1.88253 69.7 178
ATP-binding cassette sub-family A member 5 ABCA5 Tbio Transporter -1.09683 13.2 131
ATP-binding cassette sub-family D member 3 ABCD3 Tbio Transporter -1.82051 64.2 166
ATP-binding cassette sub-family A member 3 ABCA3 Tbio Transporter -2.25972 187.7 32
ATP-binding cassette sub-family A member 12 ABCA12 Tbio Transporter -2.05873 115.5 66
Solute carrier family 10 member 6 SLC10A6 Tdark Transporter -0.89661 11.2 23