Development Level

Tchem 6 | 1,598
Tbio 3 | 11,445

IMPC Phenotype

abnormal embryo size 3 | 220
abnormal bone structure 2 | 187
preweaning lethality, incomple... 2 | 499
abnormal coat- hair morphology 1 | 19
abnormal craniofacial morpholo... 1 | 33
abnormal eye morphology 1 | 68
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
anophthalmia 1 | 33
decreased startle reflex 1 | 75
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
increased prepulse inhibition 1 | 32
microphthalmia 1 | 26
pale yolk sac 1 | 25
pallor 1 | 34
preweaning lethality, complete... 1 | 979
small adrenal glands 1 | 16
small superior vagus ganglion 1 | 74
small testis 1 | 58

Disease

Carcinoma 9 | 11,493
atypical teratoid / rhabdoid tumor 7 | 5,112
ovarian cancer 7 | 8,520
glioblastoma 6 | 5,792
osteosarcoma 6 | 7,950
adult high grade glioma 5 | 3,801
medulloblastoma, large-cell 5 | 6,241
Cancer 4 | 2,499
Kidney cancer 4 | 2,613
interstitial cystitis 4 | 2,312
Astrocytoma, Pilocytic 3 | 3,081
Breast cancer 3 | 3,578
ependymoma 3 | 4,679
lung cancer 3 | 4,740
malignant mesothelioma 3 | 3,232
psoriasis 3 | 6,694
Male infertility 2 | 206
Multiple synostoses syndrome 2 | 9
Pick disease 2 | 1,894
Rheumatoid arthritis 2 | 1,191
acute myeloid leukemia 2 | 783
acute quadriplegic myopathy 2 | 1,158
astrocytic glioma 2 | 2,597
group 3 medulloblastoma 2 | 4,104
invasive ductal carcinoma 2 | 2,951
primitive neuroectodermal tumor 2 | 3,035
progressive supranuclear palsy 2 | 676
subependymal giant cell astrocytoma 2 | 2,287
ulcerative colitis 2 | 1,819
ATRIOVENTRICULAR CANAL DEFECT 1 | 17
Alzheimer's disease 1 | 658
Amyotrophic lateral sclerosis 1 | 451
Blastic phase chronic myeloid leukemia 1 | 58
Brain disease 1 | 96
Breast Neoplasms 1 | 445
Carcinoma of pancreas 1 | 5
Cardiomyopathies 1 | 110
Cholestasis 1 | 155
Chronic Myelocytic Leukemia Accelerated Phase 1 | 59
Chronic phase chronic myeloid leukemia 1 | 45
Colitis 1 | 54
Congenital heart disease 1 | 93
Coronary artery disease 1 | 268
Dextrocardia 1 | 12
Dyspnea 1 | 76
Ectopic spleen 1 | 1
Endocardial Cushion Defects 1 | 17
Familial primary pulmonary hypertension 1 | 11
Gastrointestinal stromal tumor 1 | 62
Gaucher disease type 1 1 | 180
Gout 1 | 106
HETEROTAXY, VISCERAL, 4, AUTOSOMAL 1 | 1
Hereditary hemorrhagic telangiectasia 1 | 13
Heterotaxy Syndrome 1 | 5
Hyperandrogenism 1 | 34
Hypersensitivity reaction type II disease 1 | 253
Hypertension 1 | 396
Hypertension, Pulmonary 1 | 37
Hypoxia-Ischemia, Brain 1 | 5
Idiopathic pulmonary arterial hypertension 1 | 40
Infertility 1 | 188
Liver cancer 1 | 604
Liver neoplasms 1 | 130
Lung Neoplasms 1 | 232
Lung disease 1 | 142
Mammary Neoplasms 1 | 425
Marijuana Abuse 1 | 31
Microsatellite Instability 1 | 12
Multiple Sclerosis 1 | 540
Myopathy 1 | 185
Pancreatic Neuroendocrine Tumor 1 | 45
Patellar tendinitis 1 | 2
Philadelphia Chromosome Positive Chronic Myelocytic Leukemia 1 | 45
Philadelphia chromosome-positive acute lymphoblastic leukemia 1 | 47
Pre-Eclampsia 1 | 68
Primary pulmonary hypertension 1 | 14
Pulmonary hypertension 1 | 85
RETINITIS PIGMENTOSA 70 1 | 3
Renal Cell Carcinoma 1 | 214
Right aortic arch (disorder) 1 | 1
Right atrial isomerism 1 | 29
Situs Inversus 1 | 65
Situs ambiguous 1 | 8
Situs ambiguus 1 | 25
Spider Veins 1 | 17
Telangiectasis 1 | 36
Ventricular Septal Defects 1 | 119
Visceral heterotaxy 1 | 14
Waldenstrons macroglobulinemia 1 | 765
axial spondyloarthropathy 1 | 28
breast carcinoma 1 | 1,638
chronic lymphosyte leukemia 1 | 204
colon cancer 1 | 1,478
cystic fibrosis 1 | 1,696
fascioscapulohumeral muscular dystrophy 1 | 100
inflammatory breast cancer 1 | 286
medulloblastoma 1 | 720
pediatric high grade glioma 1 | 1,064
pulmonary arterial hypertension 1 | 75
tuberculosis 1 | 2,010

Tissue

Endocrine System 9 | 18,159
Blood and immune system 8 | 16,909
Cardiovascular System 8 | 15,192
Digestive Tract 8 | 17,369
Female tissues 8 | 17,400
Liver and Pancreas 8 | 16,750
Male tissues 8 | 17,142
Nervous System 8 | 16,725
Respiratory system 8 | 16,393
Skin and soft tissues 8 | 17,230
Urinary Tract 8 | 16,678

Target Family

Kinase 6 | 634
Enzyme 3 | 4,145

GO Process

transmembrane receptor protein... 9 | 9
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Activin receptor type-2A ACVR2A Tchem Kinase -2.08745 108.0 315
Bone morphogenetic protein receptor type-2 BMPR2 Tchem Kinase -2.66587 458.1 390
A-kinase anchor protein 4 AKAP4 Tbio Enzyme -1.95952 93.1 116
Activin receptor type-1B ACVR1B Tchem Kinase -2.00550 91.2 418
A-kinase anchor protein 3 AKAP3 Tbio Enzyme -1.36635 24.0 139
Activin receptor type-2B ACVR2B Tchem Kinase -2.14321 122.9 303
Protein phosphatase 1L PPM1L Tbio Enzyme -0.74923 6.69 111
Interleukin-1 receptor-associated kinase 1 IRAK1 Tchem Kinase -2.58807 348.8 804
Mitogen-activated protein kinase 14 MAPK14 Tchem Kinase -3.36007 2240.8 1574