Development Level

Tbio 110 | 11,445
Tchem 4 | 1,598
Tdark 3 | 6,588

IMPC Phenotype

preweaning lethality, complete... 7 | 979
embryonic lethality prior to o... 3 | 239
embryonic lethality prior to t... 2 | 278
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal heart left ventricle ... 1 | 16
abnormal lens morphology 1 | 81
abnormal spleen morphology 1 | 55
cataract 1 | 92
decreased cardiac output 1 | 3
decreased cardiac stroke volum... 1 | 6
decreased circulating glucose ... 1 | 126
decreased granulocyte number 1 | 6
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
enlarged heart 1 | 210
hemorrhage 1 | 23
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased mean corpuscular hem... 1 | 96
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
prolonged QT interval 1 | 38
short tibia 1 | 97

Disease

ovarian cancer 53 | 8,520
lung cancer 41 | 4,740
Multiple myeloma 35 | 1,332
diabetes mellitus 31 | 1,728
intraductal papillary-mucinous neoplasm (IPMN) 29 | 3,291
medulloblastoma, large-cell 29 | 6,241
Carcinoma 28 | 11,493
osteosarcoma 26 | 7,950
Diamond-Blackfan anemia 24 | 31
psoriasis 19 | 6,694
Waldenstrons macroglobulinemia 18 | 765
atypical teratoid / rhabdoid tumor 17 | 5,112
glioblastoma 17 | 5,792
Breast cancer 16 | 3,578
group 3 medulloblastoma 14 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 14 | 2,955
Abnormality of the urinary system 13 | 21
Anemia 13 | 365
Anemia, Diamond-Blackfan 13 | 16
Anemia, Macrocytic 13 | 18
Cardiac Arrhythmia 13 | 103
Cardiac conduction abnormalities 13 | 78
Cleft Palate 13 | 271
Conduction disorder of the heart 13 | 79
Delayed Puberty 13 | 97
EKG abnormalities 13 | 78
Electrocardiogram abnormal 13 | 81
Electrocardiogram change 13 | 78
Fatigue 13 | 182
Hand deformities 13 | 32
Intermittent migraine headaches 13 | 68
Migraine Disorders 13 | 76
Pallor 13 | 40
Uranostaphyloschisis 13 | 167
acute quadriplegic myopathy 13 | 1,158
genital abnormal 13 | 17
reproductive system abnormality 13 | 17
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,989
sonic hedgehog group medulloblastoma 12 | 467
cystic fibrosis 11 | 1,696
oligodendroglioma 11 | 2,850
Cancer 10 | 2,499
adult high grade glioma 10 | 3,801
malignant mesothelioma 10 | 3,232
Adenocarcinoma of lung 9 | 142
Disease Progression 9 | 136
acute myeloid leukemia 9 | 783
Breast Neoplasms 8 | 445
Mammary Neoplasms 8 | 425
Stomach Neoplasms 8 | 300
astrocytoma 8 | 1,146
invasive ductal carcinoma 8 | 2,951
lung adenocarcinoma 8 | 2,716
mucosa-associated lymphoid tissue lymphoma 8 | 484
Disease Models, Animal 7 | 155
Leukoencephalopathy with vanishing white matter 7 | 20
colon cancer 7 | 1,478
subependymal giant cell astrocytoma 7 | 2,287
Autosomal recessive predisposition 6 | 1,442
Epilepsy 6 | 792
Muscle hypotonia 6 | 571
Seizures 6 | 596
non-small cell lung cancer 6 | 2,890
pancreatic cancer 6 | 2,398
primitive neuroectodermal tumor 6 | 3,035
Astrocytoma, Pilocytic 5 | 3,081
Big calvaria 5 | 147
Brain hypomyelination 5 | 11
Central nervous system demyelination 5 | 28
Childhood Ataxia with Central Nervous System Hypomyelinization 5 | 6
Decreased serum progesterone 5 | 5
Delusions 5 | 11
Developmental regression 5 | 95
Dysarthria 5 | 192
Forgetful 5 | 40
Gait, Unsteady 5 | 29
Increased head circumference 5 | 147
Increased size of cranium 5 | 147
Increased size of skull 5 | 147
Lethargy 5 | 77
Leukodystrophy 5 | 55
Leukoencephalopathies 5 | 29
Loss of developmental milestones 5 | 95
Memory Loss 5 | 40
Memory impairment 5 | 40
Mental deterioration in childhood 5 | 95
Mood swings 5 | 77
Muscle Spasticity 5 | 195
Neurodevelopmental regression 5 | 95
OVARIOLEUKODYSTROPHY 5 | 6
Optic Atrophy 5 | 242
Personality change 5 | 23
Premature Menopause 5 | 31
Prostatic Neoplasms 5 | 495
Psychomotor regression 5 | 95
Psychomotor regression beginning in infancy 5 | 95
Psychomotor regression in infants 5 | 95
Psychomotor regression, progressive 5 | 95
Reticulocytopenia 5 | 10
Secondary physiologic amenorrhea 5 | 32

Tissue

Blood and immune system 117 | 16,909
Cardiovascular System 117 | 15,192
Digestive Tract 117 | 17,369
Endocrine System 117 | 18,159
Female tissues 117 | 17,400
Liver and Pancreas 117 | 16,750
Male tissues 117 | 17,142
Nervous System 117 | 16,725
Respiratory system 117 | 16,393
Skin and soft tissues 117 | 17,230
Urinary Tract 117 | 16,678

Target Family

Non-IDG 114 | 12,091
Transporter 2 | 473
Enzyme 1 | 4,145

GO Process

translational initiation 117 | 117
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
60S ribosomal protein L3 RPL3 Tbio Non-IDG -2.02901 103.9 190
40S ribosomal protein S19 RPS19 Tbio Non-IDG -3.14746 1380.8 267
60S ribosomal protein L36 RPL36 Tbio Non-IDG -1.62928 39.9 123
Eukaryotic translation initiation factor 3 subunit C EIF3C Tbio Non-IDG -1.20680 14.1 159
Eukaryotic translation initiation factor 3 subunit B EIF3B Tbio Non-IDG -1.83618 70.5 84
60S ribosomal protein L35 RPL35 Tbio Non-IDG -1.30696 19.1 124
Translation initiation factor eIF-2B subunit delta EIF2B4 Tbio Non-IDG -1.06082 11.3 145
60S ribosomal protein L10 RPL10 Tbio Non-IDG -0.94919 8.10 191
60S ribosomal protein L13a RPL13A Tbio Non-IDG -1.64278 64.4 67
40S ribosomal protein S21 RPS21 Tbio Non-IDG -1.92202 82.6 72