Development Level

Tbio 71 | 11,445
Tchem 17 | 1,598
Tclin 3 | 613

IMPC Phenotype

preweaning lethality, complete... 10 | 979
embryonic lethality prior to t... 6 | 278
preweaning lethality, incomple... 5 | 499
embryonic lethality prior to o... 4 | 239
decreased total body fat amoun... 3 | 207
abnormal behavior 2 | 298
abnormal femur morphology 2 | 14
cardiovascular system phenotyp... 2 | 36
decreased lean body mass 2 | 135
hypoactivity 2 | 132
increased bone mineral content 2 | 108
increased circulating alkaline... 2 | 122
abnormal bone structure 1 | 187
abnormal craniofacial morpholo... 1 | 33
abnormal embryo size 1 | 220
abnormal forebrain morphology 1 | 10
abnormal gait 1 | 69
abnormal lens morphology 1 | 81
abnormal neural tube closure 1 | 46
abnormal optic disc morphology 1 | 10
abnormal retina morphology 1 | 71
abnormal retinal inner nuclear... 1 | 8
abnormal tail morphology 1 | 25
abnormal testis morphology 1 | 43
abnormal vibrissa morphology 1 | 25
brachydactyly 1 | 19
cyanosis 1 | 7
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased circulating glucose ... 1 | 126
decreased eosinophil cell numb... 1 | 24
decreased red blood cell distr... 1 | 41
decreased startle reflex 1 | 75
decreased total retina thickne... 1 | 17
decreased vertical activity 1 | 208
dilated heart left ventricle 1 | 11
edema 1 | 59
enlarged lymph nodes 1 | 37
female infertility 1 | 60
hemorrhage 1 | 23
hyperactivity 1 | 148
increased body length 1 | 32
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating alanine ... 1 | 13
increased circulating aspartat... 1 | 15
increased circulating choleste... 1 | 66
increased circulating iron lev... 1 | 30
increased circulating phosphat... 1 | 26
increased circulating potassiu... 1 | 29
increased heart left ventricle... 1 | 4
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased kidney weight 1 | 6
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 36
increased mean platelet volume 1 | 45
increased or absent threshold ... 1 | 101
increased total body fat amoun... 1 | 134
male infertility 1 | 123
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
thrombocytopenia 1 | 56
trunk curl 1 | 16

Disease

Carcinoma 59 | 11,493
ovarian cancer 58 | 8,520
osteosarcoma 54 | 7,950
glioblastoma 51 | 5,792
Cancer 46 | 2,499
psoriasis 42 | 6,694
lung cancer 36 | 4,740
medulloblastoma, large-cell 36 | 6,241
atypical teratoid / rhabdoid tumor 34 | 5,112
non-small cell lung cancer 30 | 2,890
intraductal papillary-mucinous adenoma (IPMA) 28 | 2,955
ependymoma 27 | 4,679
malignant mesothelioma 27 | 3,232
lung carcinoma 26 | 2,843
invasive ductal carcinoma 25 | 2,951
lung adenocarcinoma 25 | 2,716
Astrocytoma, Pilocytic 24 | 3,081
Breast cancer 23 | 3,578
adult high grade glioma 23 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 21 | 3,291
cystic fibrosis 20 | 1,696
group 3 medulloblastoma 20 | 4,104
pancreatic cancer 20 | 2,398
astrocytoma 19 | 1,146
diabetes mellitus 19 | 1,728
intraductal papillary-mucinous carcinoma (IPMC) 18 | 2,989
primitive neuroectodermal tumor 18 | 3,035
pituitary cancer 17 | 1,972
subependymal giant cell astrocytoma 17 | 2,287
ulcerative colitis 17 | 1,819
Kidney cancer 16 | 2,613
juvenile dermatomyositis 16 | 1,187
breast carcinoma 15 | 1,638
ductal carcinoma in situ 15 | 1,745
group 4 medulloblastoma 15 | 1,855
oligodendroglioma 15 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 15 | 1,962
tuberculosis 15 | 2,010
interstitial cystitis 14 | 2,312
Pick disease 13 | 1,894
Schizophrenia 13 | 1,160
pediatric high grade glioma 13 | 1,064
Hypertensive disease 12 | 292
Liver Cirrhosis, Experimental 12 | 769
Rheumatoid arthritis 12 | 1,191
acute quadriplegic myopathy 12 | 1,158
colon cancer 12 | 1,478
Acquired scoliosis 11 | 281
Curvature of spine 11 | 282
Prostatic Neoplasms 11 | 495
Pulmonary Fibrosis 11 | 106
acute myeloid leukemia 11 | 783
primary pancreatic ductal adenocarcinoma 11 | 1,109
Kidney disease 10 | 430
Orbital separation excessive 10 | 244
dermatomyositis 10 | 966
Atopic dermatitis 9 | 952
Autosomal recessive predisposition 9 | 1,442
Epilepsy 9 | 792
Heart disease 9 | 306
Hypertension 9 | 396
Ureteral obstruction 9 | 33
active Crohn's disease 9 | 922
active ulcerative colitis 9 | 764
astrocytic glioma 9 | 2,597
Acquired flat foot 8 | 72
Anemia 8 | 365
Aortic Valve Insufficiency 8 | 40
Coronary artery disease 8 | 268
Flatfoot 8 | 73
Hernia, Inguinal 8 | 89
Hypoplastic mandible condyle 8 | 275
Liver Cirrhosis 8 | 181
Mandibular hypoplasia 8 | 275
Micrognathism 8 | 275
Multiple myeloma 8 | 1,332
Seizures 8 | 596
Short stature 8 | 531
Waldenstrons macroglobulinemia 8 | 765
aldosterone-producing adenoma 8 | 665
gastric carcinoma 8 | 807
Alzheimer's disease 7 | 658
Arachnodactyly 7 | 49
Asthma 7 | 385
Breast Neoplasms 7 | 445
Byzanthine arch palate 7 | 194
Cardiomegaly 7 | 116
Cerebrovascular disease 7 | 238
Colorectal Neoplasms 7 | 243
Craniofacial Abnormalities 7 | 151
Increase in blood pressure 7 | 119
Mammary Neoplasms 7 | 425
Obesity 7 | 678
Parkinson's disease 7 | 392
autosomal dominant Emery-Dreifuss muscular dystrophy 7 | 510
fibroadenoma 7 | 559
gastric cancer 7 | 459
head and neck cancer 7 | 271
medulloblastoma 7 | 720
nephrosclerosis 7 | 333

Tissue

Digestive Tract 90 | 17,369
Endocrine System 90 | 18,159
Liver and Pancreas 90 | 16,750
Male tissues 90 | 17,142
Skin and soft tissues 90 | 17,230
Female tissues 89 | 17,400
Nervous System 89 | 16,725
Respiratory system 89 | 16,393
Urinary Tract 89 | 16,678
Cardiovascular System 88 | 15,192
Blood and immune system 87 | 16,909

Target Family

Non-IDG 46 | 12,091
Enzyme 18 | 4,145
Transcription Factor 14 | 1,400
Kinase 13 | 634

GO Process

transforming growth factor bet... 91 | 91
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Growth/differentiation factor 15 GDF15 Tbio Non-IDG -2.84344 761.3 702
Endoglin ENG Tbio Non-IDG -3.10482 1235.9 1622
Junctional adhesion molecule A F11R Tbio Non-IDG -2.56739 380.0 394
Transforming growth factor-beta receptor-associated protein 1 TGFBRAP1 Tbio Non-IDG -1.03126 9.10 179
Disintegrin and metalloproteinase domain-containing protein 9 ADAM9 Tchem Enzyme -2.08807 122.3 258
Latent-transforming growth factor beta-binding protein 2 LTBP2 Tbio Non-IDG -1.22721 18.2 100
Ubiquitin carboxyl-terminal hydrolase 15 USP15 Tbio Enzyme -1.64742 41.6 242
Rho guanine nucleotide exchange factor 18 ARHGEF18 Tbio Non-IDG -0.76671 7.19 177
Mothers against decapentaplegic homolog 6 SMAD6 Tbio Transcription Factor -2.07569 106.7 450
Polyubiquitin-B UBB Tbio Non-IDG -1.98860 97.4 427