Development Level

Tbio 26 | 10,625
Tchem 5 | 1,890
Tdark 4 | 7,003

Collection

Kinase: IDG Consortium (Complete/Control) 1 | 37

IMPC Phenotype

embryonic lethality prior to t... 6 | 187
embryonic lethality prior to o... 5 | 148
preweaning lethality, complete... 4 | 633
decreased mean corpuscular vol... 3 | 50
hypoactivity 2 | 89
abnormal kidney morphology 1 | 30
abnormal seminal vesicle morph... 1 | 47
cardiovascular system phenotyp... 1 | 35
decreased caudal vertebrae num... 1 | 49
decreased erythrocyte cell num... 1 | 43
decreased hemoglobin content 1 | 53
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular hem... 1 | 19
decreased mean platelet volume 1 | 12
decreased prepulse inhibition 1 | 52
decreased total body fat amoun... 1 | 186
increased mean corpuscular hem... 1 | 93
short tibia 1 | 82
small adrenal glands 1 | 15
small lymph nodes 1 | 1
thrombocytosis 1 | 23

Disease

ovarian cancer 17 | 8,491
osteosarcoma 16 | 7,933
glioblastoma 15 | 5,572
medulloblastoma, large-cell 15 | 6,234
psoriasis 14 | 6,685
atypical teratoid / rhabdoid tumor 11 | 4,369
Pick disease 10 | 1,893
ependymoma 10 | 2,514
oligodendroglioma 10 | 2,849
astrocytic glioma 9 | 2,241
primitive neuroectodermal tumor 9 | 3,031
lung carcinoma 8 | 2,844
pilocytic astrocytoma 8 | 3,086
Breast cancer 7 | 3,098
subependymal giant cell astrocytoma 7 | 2,287
Multiple myeloma 6 | 1,327
adult high grade glioma 6 | 2,148
invasive ductal carcinoma 6 | 2,950
medulloblastoma 6 | 1,524
Alzheimer's disease 5 | 644
Anemia 5 | 252
Osteopetrosis 5 | 40
pediatric high grade glioma 5 | 2,712
pituitary cancer 5 | 1,972
Hemochromatosis 4 | 55
Parkinson's disease 4 | 364
astrocytoma 4 | 1,493
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,289
lung cancer 4 | 4,473
pancreatic cancer 4 | 2,300
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,795
sonic hedgehog group medulloblastoma 4 | 1,482
tuberculosis 4 | 1,563
tuberculosis and treatment for 6 months 4 | 686
Aceruloplasminemia 3 | 17
Cancer 3 | 2,346
Carcinoma 3 | 2,147
Cutis laxa 3 | 28
Iron deficiency anemia 3 | 6
Kidney disease 3 | 397
Thalassemia 3 | 46
Waldenstrons macroglobulinemia 3 | 764
acute quadriplegic myopathy 3 | 1,157
atypical teratoid/rhabdoid tumor 3 | 1,095
breast carcinoma 3 | 1,614
chronic rhinosinusitis 3 | 512
colon cancer 3 | 1,475
cystic fibrosis 3 | 1,670
diabetes mellitus 3 | 1,663
group 3 medulloblastoma 3 | 2,254
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,988
lung adenocarcinoma 3 | 2,714
malignant mesothelioma 3 | 3,163
Atransferrinemia 2 | 8
Beta thalassemia 2 | 19
Enlarged vestibular aqueduct 2 | 10
Gaucher disease type 1 2 | 171
Hypersensitivity reaction type II disease 2 | 235
Inflammation 2 | 109
Iron metabolism disease 2 | 17
Liver disease 2 | 219
Malaria 2 | 140
Metabolic acidosis 2 | 49
Neurodegenerative disease 2 | 383
Obesity 2 | 616
Peripheral vascular disease 2 | 90
Sensorineural hearing loss 2 | 107
dermatomyositis 2 | 966
ductal carcinoma in situ 2 | 1,745
esophageal adenocarcinoma 2 | 737
glioblastoma multiforme 2 | 347
hepatocellular carcinoma 2 | 550
nasopharyngeal carcinoma 2 | 1,056
non-small cell lung cancer 2 | 2,798
posterior fossa group A ependymoma 2 | 1,511
posterior fossa group B ependymoma 2 | 1,530
progressive supranuclear palsy 2 | 674
Alcoholic Intoxication, Chronic 1 | 41
Calcinosis 1 | 63
Centronuclear myopathy 1 | 21
Coloboma 1 | 52
Diarrhea 1 | 155
Diffuse large B-cell lymphoma 1 | 42
Echinococcosis 1 | 28
Glycoproteinosis 1 | 13
Histoplasmosis 1 | 22
Human immunodeficiency virus infectious disease 1 | 129
Hypokalemia 1 | 40
Hypokalemic periodic paralysis 1 | 13
Inflammatory myofibroblastic tumor 1 | 8
Myocardial Reperfusion Injury 1 | 34
Neoplastic Cell Transformation 1 | 81
Osteopetrosis autosomal recessive 1 1 | 2
Osteopetrosis, Autosomal Recessive 1 1 | 2
Ovarian Cysts 1 | 34
Pigmented villonodular synovitis 1 | 9
Pulmonary emphysema 1 | 34
Restless legs syndrome 1 | 28
Sickle Cell Anemia 1 | 54

Tissue

Blood and immune system 35 | 17,994
Cardiovascular System 35 | 17,957
Digestive Tract 35 | 18,472
Male tissues 35 | 17,968
Nervous System 35 | 18,560
Skin and soft tissues 35 | 18,114
Urinary Tract 35 | 18,443
Endocrine System 34 | 18,511
Female tissues 34 | 18,646
Liver and Pancreas 34 | 18,135
Respiratory system 34 | 17,483

Target Family

Enzyme 27 | 4,146
Non-IDG 5 | 11,969
Ion Channel 1 | 341
Kinase 1 | 634
Transporter 1 | 473

GO Process

transferrin transport 35 | 35
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 367 | 367
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
chemical synaptic transmission 238 | 238
MAPK cascade 237 | 237
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 199 | 199
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 180 | 180
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 175 | 175
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
protein folding 162 | 162
negative regulation of canonic... 161 | 161
response to lipopolysaccharide 161 | 161
T cell receptor signaling path... 160 | 160
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2-M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
type I interferon signaling pa... 130 | 130
endocytosis 129 | 129

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Rab15 effector protein REP15 Tbio Non-IDG -0.44863 2.71 15
V-type proton ATPase 16 kDa proteolipid subunit ATP6V0C Tbio Enzyme -1.84880 72.6 59
Clathrin heavy chain 1 CLTC Tbio Non-IDG -1.63705 36.3 159
V-type proton ATPase subunit G 3 ATP6V1G3 Tbio Enzyme -0.65332 4.31 51
Metalloreductase STEAP3 STEAP3 Tbio Enzyme -1.38506 25.1 187
V-type proton ATPase subunit G 1 ATP6V1G1 Tbio Enzyme -0.84169 6.10 96
V-type proton ATPase subunit E 2 ATP6V1E2 Tdark Enzyme -0.78312 6.48 48
V-type proton ATPase subunit E 1 ATP6V1E1 Tbio Enzyme -1.02510 10.3 111
V-type proton ATPase subunit e 2 ATP6V0E2 Tdark Enzyme 0.18 0.40 19
V-type proton ATPase subunit d 1 ATP6V0D1 Tbio Enzyme -1.02895 9.11 127