Development Level

Tbio 29 | 11,445
Tchem 5 | 1,598
Tdark 2 | 6,588

Collection

Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

embryonic lethality prior to o... 6 | 239
embryonic lethality prior to t... 6 | 278
preweaning lethality, complete... 6 | 979
abnormal behavior 4 | 298
decreased total body fat amoun... 3 | 207
decreased mean corpuscular vol... 2 | 79
hyperactivity 2 | 148
abnormal kidney morphology 1 | 65
abnormal seminal vesicle morph... 1 | 114
brachydactyly 1 | 19
cardiovascular system phenotyp... 1 | 36
decreased caudal vertebrae num... 1 | 53
decreased circulating bilirubi... 1 | 19
decreased erythrocyte cell num... 1 | 62
decreased hemoglobin content 1 | 68
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean platelet volume 1 | 25
decreased prepulse inhibition 1 | 82
hypoactivity 1 | 132
increased bone mineral content 1 | 108
increased circulating alkaline... 1 | 122
increased circulating iron lev... 1 | 30
increased heart rate variabili... 1 | 7
increased mean corpuscular hem... 1 | 96
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased or absent threshold ... 1 | 101
preweaning lethality, incomple... 1 | 499
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
short tibia 1 | 97
small adrenal glands 1 | 16
small lymph nodes 1 | 1
syndactyly 1 | 23
thrombocytosis 1 | 27

Disease

Carcinoma 22 | 11,493
osteosarcoma 17 | 7,950
ovarian cancer 17 | 8,520
ependymoma 15 | 4,679
atypical teratoid / rhabdoid tumor 14 | 5,112
glioblastoma 14 | 5,792
medulloblastoma, large-cell 14 | 6,241
psoriasis 14 | 6,694
astrocytic glioma 11 | 2,597
Pick disease 10 | 1,894
oligodendroglioma 10 | 2,850
primitive neuroectodermal tumor 9 | 3,035
Astrocytoma, Pilocytic 8 | 3,081
Autosomal recessive predisposition 8 | 1,442
Breast cancer 8 | 3,578
lung carcinoma 8 | 2,843
Anemia 7 | 365
adult high grade glioma 7 | 3,801
group 3 medulloblastoma 7 | 4,104
subependymal giant cell astrocytoma 7 | 2,287
Kidney cancer 6 | 2,613
Multiple myeloma 6 | 1,332
Alzheimer's disease 5 | 658
Osteopetrosis 5 | 43
diabetes mellitus 5 | 1,728
invasive ductal carcinoma 5 | 2,951
lung cancer 5 | 4,740
pituitary cancer 5 | 1,972
tuberculosis 5 | 2,010
Cancer 4 | 2,499
Cutis Laxa 4 | 39
Hemochromatosis 4 | 54
Neurodegenerative disease 4 | 414
Thalassemia 4 | 53
cystic fibrosis 4 | 1,696
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
malignant mesothelioma 4 | 3,232
pancreatic cancer 4 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
Atransferrinemia 3 | 8
Failure to gain weight 3 | 365
Hemoglobin low 3 | 124
Hemolytic anemia 3 | 77
Hepatomegaly 3 | 285
Hyperferritinaemia 3 | 14
Increased ferritin 3 | 14
Iron deficiency anemia 3 | 12
Iron metabolism disease 3 | 20
Kidney disease 3 | 430
Liver disease 3 | 237
Osteoporosis 3 | 363
Pediatric failure to thrive 3 | 365
Peripheral vascular disease 3 | 87
Schizophrenia 3 | 1,160
Serum ferritin increased 3 | 14
Splenomegaly 3 | 190
Waldenstrons macroglobulinemia 3 | 765
acute quadriplegic myopathy 3 | 1,158
astrocytoma 3 | 1,146
breast carcinoma 3 | 1,638
chronic rhinosinusitis 3 | 512
dermatomyositis 3 | 966
group 4 medulloblastoma 3 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
medulloblastoma 3 | 720
pediatric high grade glioma 3 | 1,064
tuberculosis and treatment for 6 months 3 | 409
Alzheimer Disease 2 | 83
Bell Palsy 2 | 58
Broad flat nasal bridge 2 | 236
Elevated hepatic transaminases 2 | 81
Epilepsy 2 | 792
Facial Paresis 2 | 59
Facial muscle weakness of muscles innervated by CN VII 2 | 58
Hepatic enzyme increased 2 | 81
Liver Cirrhosis 2 | 181
Liver Dysfunction 2 | 99
Liver cancer 2 | 604
Liver enzymes abnormal 2 | 81
Liver function test increased 2 | 81
Liver function tests abnormal finding 2 | 81
Malaria 2 | 160
Motor delay 2 | 147
Nasal bridge wide 2 | 236
Nephrocalcinosis 2 | 35
No development of motor milestones 2 | 147
Parkinson's disease 2 | 392
Schizoaffective Disorder 2 | 55
Seizures 2 | 596
Subclinical abnormal liver function tests 2 | 81
Transaminases increased 2 | 81
colon cancer 2 | 1,478
esophageal adenocarcinoma 2 | 737
glioblastoma multiforme 2 | 142
hepatocellular carcinoma 2 | 547
lung adenocarcinoma 2 | 2,716
nasopharyngeal carcinoma 2 | 1,058
progressive supranuclear palsy 2 | 676
substance-related disorder 2 | 162

Tissue

Blood and immune system 36 | 16,909
Digestive Tract 35 | 17,369
Endocrine System 35 | 18,159
Female tissues 35 | 17,400
Male tissues 35 | 17,142
Nervous System 35 | 16,725
Urinary Tract 35 | 16,678
Liver and Pancreas 34 | 16,750
Respiratory system 34 | 16,393
Skin and soft tissues 34 | 17,230
Cardiovascular System 33 | 15,192

Target Family

Enzyme 28 | 4,145
Non-IDG 6 | 12,091
Ion Channel 1 | 344
Kinase 1 | 634

GO Process

transferrin transport 36 | 36
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Rab15 effector protein REP15 Tbio Non-IDG -0.44863 2.71 21
V-type proton ATPase 116 kDa subunit a isoform 4 ATP6V0A4 Tbio Enzyme -2.84949 692.2 90
Serotransferrin TF Tbio Non-IDG -4.15070 13447.9 1168
Transferrin receptor protein 1 TFRC Tbio Non-IDG -3.43851 2558.3 1677
Serine/threonine-protein kinase LMTK2 LMTK2 Tbio Kinase -1.46351 31.6 189
Clathrin heavy chain 1 CLTC Tbio Non-IDG -1.66258 38.8 231
V-type proton ATPase subunit C 1 ATP6V1C1 Tbio Enzyme -1.31659 21.7 102
V-type proton ATPase subunit B, brain isoform ATP6V1B2 Tchem Enzyme -1.39933 24.1 157
V-type proton ATPase subunit F ATP6V1F Tbio Enzyme -0.91914 8.76 118
Mucolipin-1 MCOLN1 Tchem Ion Channel -2.43459 272.2 132