Development Level

Tbio 100 | 11,445
Tchem 38 | 1,598
Tclin 19 | 613
Tdark 3 | 6,588

IMPC Phenotype

preweaning lethality, complete... 23 | 979
embryonic lethality prior to t... 11 | 278
embryonic lethality prior to o... 10 | 239
abnormal heart morphology 7 | 162
enlarged heart 7 | 210
abnormal embryo size 6 | 220
preweaning lethality, incomple... 6 | 499
decreased vertical activity 5 | 208
abnormal bone structure 4 | 187
abnormal retina morphology 4 | 71
decreased total body fat amoun... 4 | 207
increased bone mineral content 4 | 108
abnormal behavior 3 | 298
abnormal embryo turning 3 | 31
abnormal eye morphology 3 | 68
abnormal neural tube closure 3 | 46
abnormal seminal vesicle morph... 3 | 114
decreased lean body mass 3 | 135
decreased mean corpuscular vol... 3 | 79
embryonic growth retardation 3 | 106
increased bone mineral density 3 | 72
increased circulating HDL chol... 3 | 80
increased lean body mass 3 | 172
increased startle reflex 3 | 112
increased total body fat amoun... 3 | 134
pale yolk sac 3 | 25
abnormal epididymis morphology 2 | 42
abnormal forebrain development 2 | 20
abnormal kidney morphology 2 | 65
abnormal placenta size 2 | 20
decreased bone mineral content 2 | 151
decreased bone mineral density 2 | 126
decreased caudal vertebrae num... 2 | 53
decreased prepulse inhibition 2 | 82
enlarged epididymis 2 | 31
hyperactivity 2 | 148
improved glucose tolerance 2 | 79
increased anti-nuclear antigen... 2 | 19
increased circulating choleste... 2 | 66
increased circulating potassiu... 2 | 29
increased circulating triglyce... 2 | 42
increased hemoglobin content 2 | 45
increased or absent threshold ... 2 | 101
microphthalmia 2 | 26
short tibia 2 | 97
thin ventricular wall 2 | 24
abnormal allantois morphology 1 | 8
abnormal behavioral response t... 1 | 66
abnormal chorioallantoic fusio... 1 | 8
abnormal craniofacial morpholo... 1 | 33
abnormal gait 1 | 69
abnormal heart left ventricle ... 1 | 16
abnormal heart looping 1 | 5
abnormal lens morphology 1 | 81
abnormal locomotor activation 1 | 16
abnormal lung morphology 1 | 26
abnormal motor capabilities-co... 1 | 5
abnormal neural tube morpholog... 1 | 12
abnormal pericardium morpholog... 1 | 26
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal somite shape 1 | 5
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
abnormal tooth morphology 1 | 24
abnormal vertebrae morphology 1 | 18
abnormal visceral yolk sac mor... 1 | 6
cataract 1 | 92
decreased T cell number 1 | 15
decreased anxiety-related resp... 1 | 12
decreased body length 1 | 101
decreased circulating creatini... 1 | 39
decreased circulating insulin ... 1 | 76
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased heart left ventricle... 1 | 28
decreased neutrophil cell numb... 1 | 42
dilated heart left ventricle 1 | 11
edema 1 | 59
enlarged spleen 1 | 41
enlarged uterus 1 | 11
hydrometra 1 | 53
increased circulating alanine ... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating aspartat... 1 | 15
increased circulating creatini... 1 | 38
increased circulating serum al... 1 | 22
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 28
increased heart rate 1 | 23
increased heart weight 1 | 62
increased lactate dehydrogenas... 1 | 3
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
shortened RR interval 1 | 17
small superior vagus ganglion 1 | 74
small testis 1 | 58
tremors 1 | 39
urinary bladder obstruction 1 | 4

Disease

Carcinoma 104 | 11,493
ovarian cancer 91 | 8,520
osteosarcoma 90 | 7,950
psoriasis 64 | 6,694
lung cancer 62 | 4,740
Cancer 56 | 2,499
medulloblastoma, large-cell 56 | 6,241
glioblastoma 50 | 5,792
group 3 medulloblastoma 47 | 4,104
atypical teratoid / rhabdoid tumor 44 | 5,112
Breast cancer 43 | 3,578
malignant mesothelioma 39 | 3,232
ependymoma 33 | 4,679
primitive neuroectodermal tumor 33 | 3,035
adult high grade glioma 32 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 30 | 3,291
invasive ductal carcinoma 29 | 2,951
pituitary cancer 28 | 1,972
ductal carcinoma in situ 26 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 26 | 2,989
Kidney cancer 25 | 2,613
intraductal papillary-mucinous adenoma (IPMA) 25 | 2,955
Endometriosis 24 | 540
lung adenocarcinoma 24 | 2,716
oligodendroglioma 24 | 2,850
astrocytoma 23 | 1,146
breast carcinoma 23 | 1,638
diabetes mellitus 23 | 1,728
ulcerative colitis 23 | 1,819
astrocytic glioma 22 | 2,597
pancreatic cancer 22 | 2,398
Astrocytoma, Pilocytic 21 | 3,081
group 4 medulloblastoma 21 | 1,855
subependymal giant cell astrocytoma 21 | 2,287
Breast Neoplasms 20 | 445
interstitial cystitis 20 | 2,312
Mammary Neoplasms 19 | 425
Pick disease 19 | 1,894
Rheumatoid arthritis 19 | 1,191
Schizophrenia 19 | 1,160
lung carcinoma 19 | 2,843
Intellectual disability 18 | 1,016
non-small cell lung cancer 18 | 2,890
Autosomal recessive predisposition 17 | 1,442
Obesity 17 | 678
tuberculosis 17 | 2,010
colon cancer 16 | 1,478
pancreatic ductal adenocarcinoma liver metastasis 16 | 1,962
Bipolar Disorder 15 | 666
adrenocortical carcinoma 15 | 1,428
cystic fibrosis 15 | 1,696
Prostatic Neoplasms 14 | 495
Atopic dermatitis 13 | 952
Multiple myeloma 13 | 1,332
Polycystic ovary syndrome 13 | 360
acute quadriplegic myopathy 13 | 1,158
juvenile dermatomyositis 13 | 1,187
primary pancreatic ductal adenocarcinoma 13 | 1,109
spina bifida 13 | 1,074
Cockayne syndrome 12 | 60
Depressive disorder 12 | 409
Dull intelligence 12 | 645
Low intelligence 12 | 645
Mental Retardation 12 | 645
Mental deficiency 12 | 645
Photosensitive trichothiodystrophy 12 | 30
Poor school performance 12 | 645
acute myeloid leukemia 12 | 783
dermatomyositis 12 | 966
pediatric high grade glioma 12 | 1,064
Acne vulgaris 11 | 14
Cryptorchidism 11 | 296
Failure to gain weight 11 | 365
Hypertension 11 | 396
Muscle hypotonia 11 | 571
Osteoporosis 11 | 363
Pediatric failure to thrive 11 | 365
Short stature 11 | 531
Xeroderma pigmentosum group B 11 | 20
Carcinoma, Hepatocellular 10 | 228
Liver carcinoma 10 | 240
Melanoma 10 | 711
nasopharyngeal carcinoma 10 | 1,058
Adenocarcinoma 9 | 122
Alzheimer's disease 9 | 658
Epilepsy 9 | 792
Heart disease 9 | 306
Hypoplastic mandible condyle 9 | 275
Kidney disease 9 | 430
Lung Neoplasms 9 | 232
Mandibular hypoplasia 9 | 275
Micrognathism 9 | 275
Strabismus 9 | 270
gastric carcinoma 9 | 807
Mental Depression 8 | 333
aldosterone-producing adenoma 8 | 665
autosomal dominant Emery-Dreifuss muscular dystrophy 8 | 510
cutaneous lupus erythematosus 8 | 1,057
esophageal adenocarcinoma 8 | 737
hepatocellular carcinoma 8 | 547

Tissue

Endocrine System 159 | 18,159
Skin and soft tissues 158 | 17,230
Blood and immune system 157 | 16,909
Digestive Tract 157 | 17,369
Female tissues 157 | 17,400
Male tissues 156 | 17,142
Respiratory system 156 | 16,393
Liver and Pancreas 155 | 16,750
Urinary Tract 155 | 16,678
Nervous System 151 | 16,725
Cardiovascular System 150 | 15,192

Target Family

Non-IDG 49 | 12,091
Nuclear Receptor 47 | 48
Enzyme 37 | 4,145
Transcription Factor 15 | 1,400
Kinase 7 | 634
Epigenetic 5 | 242

GO Process

transcription initiation from ... 160 | 160
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nuclear receptor 2C2-associated protein NR2C2AP Tbio Non-IDG -0.49369 3.49 124
Mediator of RNA polymerase II transcription subunit 15 MED15 Tbio Enzyme -1.60315 40.6 144
DNA-directed RNA polymerase II subunit RPB2 POLR2B Tbio Enzyme -2.49730 299.8 149
Photoreceptor-specific nuclear receptor NR2E3 Tbio Nuclear Receptor 0.00000 261
Mediator of RNA polymerase II transcription subunit 16 MED16 Tbio Enzyme -0.82499 7.04 154
Thyroid hormone receptor-associated protein 3 THRAP3 Tbio Non-IDG -0.87769 8.81 136
Steroid hormone receptor ERR2 ESRRB Tchem Nuclear Receptor -1.95523 86.9 173
Mediator of RNA polymerase II transcription subunit 31 MED31 Tbio Enzyme -1.19048 15.1 61
Mediator of RNA polymerase II transcription subunit 13 MED13 Tbio Enzyme -1.52250 26.0 53
Nuclear receptor subfamily 2 group C member 1 NR2C1 Tbio Nuclear Receptor -1.39182 24.4 294