Development Level

Tbio 89 | 10,625
Tchem 37 | 1,890
Tclin 18 | 602
Tdark 6 | 7,003

IMPC Term

preweaning lethality, complete... 17 | 633
embryonic lethality prior to t... 7 | 187
embryonic lethality prior to o... 5 | 148
preweaning lethality, incomple... 5 | 260
abnormal retina morphology 4 | 100
abnormal behavior 3 | 226
abnormal embryo size 3 | 112
decreased Ly6C low monocyte nu... 3 | 23
decreased body length 3 | 108
decreased caudal vertebrae num... 3 | 49
decreased total body fat amoun... 3 | 186
enlarged heart 3 | 111
increased circulating triglyce... 3 | 24
abnormal bone structure 2 | 131
abnormal embryo turning 2 | 15
abnormal eye morphology 2 | 38
abnormal heart morphology 2 | 51
decreased hemoglobin content 2 | 53
increased Ly6C high monocyte n... 2 | 12
increased circulating HDL chol... 2 | 63
increased circulating choleste... 2 | 53
increased or absent threshold ... 2 | 128
pale yolk sac 2 | 12
short tibia 2 | 82
abnormal QRS complex 1 | 25
abnormal allantois morphology 1 | 3
abnormal embryo development 1 | 2
abnormal epididymis morphology 1 | 31
abnormal forebrain development 1 | 18
abnormal gait 1 | 51
abnormal heart looping 1 | 2
abnormal hindbrain development 1 | 24
abnormal iris morphology 1 | 12
abnormal lens morphology 1 | 73
abnormal locomotor activation 1 | 26
abnormal lumbar vertebrae morp... 1 | 6
abnormal midbrain development 1 | 22
abnormal motor capabilities/co... 1 | 4
abnormal neural tube closure 1 | 37
abnormal neural tube morpholog... 1 | 8
abnormal pericardium morpholog... 1 | 11
abnormal pharyngeal arch morph... 1 | 2
abnormal placenta size 1 | 10
abnormal retinal pigmentation 1 | 61
abnormal skin morphology 1 | 23
abnormal tail bud morphology 1 | 6
abnormal visceral yolk sac mor... 1 | 2
absent heartbeat 1 | 6
cataract 1 | 26
decreased CD103-positive CD11b... 1 | 2
decreased CD4-positive, CD25-p... 1 | 24
decreased anxiety-related resp... 1 | 12
decreased bone mineral density 1 | 126
decreased cardiac output 1 | 2
decreased circulating HDL chol... 1 | 77
decreased circulating choleste... 1 | 85
decreased circulating creatini... 1 | 31
decreased circulating glycerol... 1 | 19
decreased circulating serum al... 1 | 79
decreased circulating sodium l... 1 | 18
decreased circulating triglyce... 1 | 83
decreased eosinophil cell numb... 1 | 41
decreased gamma-delta T cell n... 1 | 18
decreased grip strength 1 | 123
decreased heart weight 1 | 44
decreased lean body mass 1 | 195
decreased mean corpuscular vol... 1 | 50
decreased prepulse inhibition 1 | 52
decreased vertical activity 1 | 22
embryonic growth retardation 1 | 28
enlarged kidney 1 | 7
hyperactivity 1 | 108
hypoactivity 1 | 89
increased bone mineral content 1 | 92
increased circulating alanine ... 1 | 11
increased circulating alkaline... 1 | 119
increased circulating aspartat... 1 | 17
increased circulating creatini... 1 | 29
increased circulating free fat... 1 | 17
increased circulating iron lev... 1 | 25
increased circulating potassiu... 1 | 31
increased circulating sodium l... 1 | 71
increased effector memory CD4-... 1 | 15
increased exploration in new e... 1 | 56
increased grip strength 1 | 83
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
increased lactate dehydrogenas... 1 | 3
increased lean body mass 1 | 107
increased mean corpuscular vol... 1 | 91
increased plasma cell number 1 | 5
increased respiratory quotient 1 | 12
increased total body fat amoun... 1 | 57
irregularly shaped pupil 1 | 7
pale liver 1 | 5
persistence of hyaloid vascula... 1 | 22
straub tail 1 | 26
thin ventricular wall 1 | 5
tremors 1 | 34
vertebral transformation 1 | 12

Disease

osteosarcoma 83 | 7,933
ovarian cancer 82 | 8,492
psoriasis 58 | 6,685
lung cancer 53 | 4,473
medulloblastoma, large-cell 48 | 6,234
Cancer 47 | 2,346
glioblastoma 38 | 5,572
atypical teratoid / rhabdoid tumor 37 | 4,369
malignant mesothelioma 33 | 3,163
Breast cancer 28 | 3,099
primitive neuroectodermal tumor 28 | 3,031
intraductal papillary-mucinous neoplasm (IPMN) 27 | 3,289
group 4 medulloblastoma 26 | 1,875
invasive ductal carcinoma 25 | 2,950
pituitary cancer 24 | 1,972
group 3 medulloblastoma 23 | 2,254
intraductal papillary-mucinous adenoma (IPMA) 23 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 23 | 2,988
Endometriosis 22 | 535
pediatric high grade glioma 21 | 2,712
ulcerative colitis 21 | 2,087
Carcinoma 20 | 2,147
astrocytoma 20 | 1,493
breast carcinoma 20 | 1,614
diabetes mellitus 20 | 1,663
ductal carcinoma in situ 20 | 1,745
interstitial cystitis 19 | 2,299
lung adenocarcinoma 19 | 2,714
lung carcinoma 19 | 2,844
oligodendroglioma 19 | 2,849
Pick disease 18 | 1,893
Rheumatoid Arthritis 18 | 1,171
astrocytic glioma 18 | 2,241
ependymoma 18 | 2,514
pancreatic cancer 18 | 2,300
subependymal giant cell astrocytoma 17 | 2,287
Mammary Neoplasms 16 | 410
adult high grade glioma 16 | 2,148
pilocytic astrocytoma 15 | 3,086
Obesity 14 | 616
pancreatic ductal adenocarcinoma liver metastasis 14 | 1,795
Multiple myeloma 13 | 1,328
cystic fibrosis 13 | 1,670
non-small cell lung cancer 13 | 2,798
tuberculosis 13 | 1,563
adrenocortical carcinoma 12 | 1,427
dermatomyositis 12 | 967
medulloblastoma 12 | 1,524
posterior fossa group A ependymoma 12 | 1,511
primary pancreatic ductal adenocarcinoma 12 | 1,271
Atopic dermatitis 11 | 944
Prostatic Neoplasms 11 | 471
acute quadriplegic myopathy 11 | 1,157
colon cancer 11 | 1,475
juvenile dermatomyositis 11 | 1,189
spina bifida 11 | 1,064
Acne vulgaris 10 | 16
Metabolic syndrome X 10 | 155
Photosensitive trichothiodystrophy 10 | 24
acute myeloid leukemia 10 | 785
sonic hedgehog group medulloblastoma 10 | 1,482
Cockayne syndrome 9 | 54
Heart disease 9 | 279
Intellectual disability 9 | 573
Peripheral Neuropathy 9 | 303
Adenocarcinoma 8 | 115
Hypertension 8 | 293
Liver carcinoma 8 | 217
Polycystic Ovary Syndrome 8 | 335
aldosterone-producing adenoma 8 | 664
gastric carcinoma 8 | 832
Alzheimer's disease 7 | 644
Amyotrophic Lateral Sclerosis 7 | 432
Bipolar Disorder 7 | 266
Drug-Induced Liver Injury 7 | 118
Hypertensive disease 7 | 193
Infertility 7 | 163
Kaposi's Sarcoma Skin Lesions 7 | 7
Kidney disease 7 | 397
Liver disease 7 | 219
Menopausal flushing 7 | 17
atypical teratoid/rhabdoid tumor 7 | 1,095
autosomal dominant Emery-Dreifuss muscular dystrophy 7 | 499
cutaneous lupus erythematosus 7 | 1,056
hepatocellular carcinoma 7 | 550
Adenoma 6 | 165
Atrophic vaginitis 6 | 14
Cholestasis 6 | 93
Crohn's disease 6 | 304
Duchenne muscular dystrophy 6 | 602
Postmenopausal osteoporosis 6 | 19
Waldenstrons macroglobulinemia 6 | 765
chronic rhinosinusitis 6 | 512
esophageal adenocarcinoma 6 | 737
gastric cancer 6 | 436
nasopharyngeal carcinoma 6 | 1,056
nephrosclerosis 6 | 329
pancreatic carcinoma 6 | 567
tuberculosis and treatment for 6 months 6 | 686
urothelial carcinoma 6 | 318

Tissue

Nervous System 149 | 18,561
Blood and immune system 148 | 17,995
Cardiovascular System 148 | 17,958
Digestive Tract 148 | 18,473
Endocrine System 148 | 18,512
Female tissues 148 | 18,647
Liver and Pancreas 148 | 18,136
Male tissues 148 | 17,969
Respiratory system 147 | 17,484
Urinary Tract 147 | 18,444
Skin and soft tissues 146 | 18,115

Target Family

Nuclear Receptor 47 | 48
Non-IDG 46 | 11,969
Enzyme 35 | 4,146
Transcription Factor 12 | 1,400
Epigenetic 5 | 242
Kinase 5 | 634

GO Process

transcription initiation from ... 150 | 150
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transcriptional enhancer factor TEF-1 TEAD1 Tbio Transcription Factor -1.64251 37.7 135
Thyroid hormone receptor-associated protein 3 THRAP3 Tbio Non-IDG -0.80588 7.46 119
Nuclear receptor subfamily 2 group C member 1 NR2C1 Tbio Nuclear Receptor -1.36299 21.6 224
Mediator of RNA polymerase II transcription subunit 31 MED31 Tdark Enzyme -1.14629 14.6 47
Mediator of RNA polymerase II transcription subunit 13 MED13 Tbio Enzyme -1.45091 21.4 49
Transcription initiation factor TFIID subunit 9B TAF9B Tbio Non-IDG -1.37920 23.3 85
Nuclear receptor-binding protein NRBP1 Tbio Kinase -0.83639 9.04 223
Nuclear receptor subfamily 2 group C member 2 NR2C2 Tchem Nuclear Receptor -1.68095 43.4 403
Natriuretic peptides A NPPA Tchem Non-IDG -3.23922 1719.8 429
TFIIA-alpha and beta-like factor GTF2A1L Tbio Non-IDG -0.66901 3.86 184