Development Level

Tbio 243 | 11,445
Tchem 20 | 1,598
Tdark 19 | 6,588
Tclin 4 | 613

IMPC Phenotype

preweaning lethality, complete... 32 | 979
embryonic lethality prior to t... 12 | 278
embryonic lethality prior to o... 11 | 239
preweaning lethality, incomple... 10 | 499
abnormal embryo size 6 | 220
decreased total body fat amoun... 6 | 207
decreased bone mineral density 5 | 126
improved glucose tolerance 5 | 79
increased lean body mass 5 | 172
male infertility 5 | 123
abnormal bone structure 4 | 187
abnormal heart morphology 4 | 162
decreased vertical activity 4 | 208
embryonic growth retardation 4 | 106
female infertility 4 | 60
impaired glucose tolerance 4 | 75
increased circulating HDL chol... 4 | 80
thrombocytopenia 4 | 56
abnormal cornea morphology 3 | 31
decreased body length 3 | 101
decreased circulating glucose ... 3 | 126
decreased circulating triglyce... 3 | 79
decreased leukocyte cell numbe... 3 | 73
decreased lymphocyte cell numb... 3 | 83
enlarged heart 3 | 210
increased circulating alkaline... 3 | 122
increased circulating potassiu... 3 | 29
prenatal lethality prior to he... 3 | 87
short tibia 3 | 97
abnormal behavior 2 | 298
abnormal behavioral response t... 2 | 66
abnormal forebrain development 2 | 20
abnormal hindbrain development 2 | 16
abnormal neural tube closure 2 | 46
abnormal pericardium morpholog... 2 | 26
abnormal retina morphology 2 | 71
abnormal seminal vesicle morph... 2 | 114
abnormal skin morphology 2 | 50
abnormal thymus morphology 2 | 7
cardiovascular system phenotyp... 2 | 36
decreased IgG1 level 2 | 8
decreased blood urea nitrogen ... 2 | 51
decreased body weight 2 | 161
decreased bone mineral content 2 | 151
decreased circulating amylase ... 2 | 28
decreased circulating sodium l... 2 | 22
decreased neutrophil cell numb... 2 | 42
decreased prepulse inhibition 2 | 82
decreased red blood cell distr... 2 | 41
increased bone mineral density 2 | 72
increased cardiac muscle contr... 2 | 8
increased circulating choleste... 2 | 66
increased circulating free fat... 2 | 20
increased circulating triglyce... 2 | 42
increased grip strength 2 | 41
increased heart rate 2 | 23
increased leukocyte cell numbe... 2 | 47
increased lymphocyte cell numb... 2 | 32
increased mean corpuscular vol... 2 | 92
increased monocyte cell number 2 | 63
increased startle reflex 2 | 112
increased total body fat amoun... 2 | 134
microphthalmia 2 | 26
shortened RR interval 2 | 17
small testis 2 | 58
abnormal cranium morphology 1 | 36
abnormal ear morphology 1 | 9
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
abnormal head morphology 1 | 10
abnormal heart left ventricle ... 1 | 16
abnormal retinal inner nuclear... 1 | 8
abnormal spleen morphology 1 | 55
absent spleen 1 | 3
decreased T cell number 1 | 15
decreased caudal vertebrae num... 1 | 53
decreased circulating chloride... 1 | 30
decreased circulating potassiu... 1 | 20
decreased grip strength 1 | 116
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 31
decreased total retina thickne... 1 | 17
enlarged spleen 1 | 41
enlarged urinary bladder 1 | 8
hydrometra 1 | 53
impaired pupillary reflex 1 | 26
increased anti-nuclear antigen... 1 | 19
increased body weight 1 | 25
increased circulating amylase ... 1 | 25
increased circulating aspartat... 1 | 15
increased circulating creatine... 1 | 5
increased circulating fructosa... 1 | 13
increased circulating phosphat... 1 | 26
increased fasted circulating g... 1 | 76
increased heart weight 1 | 62
increased mean platelet volume 1 | 45
prenatal lethality 1 | 28
small superior vagus ganglion 1 | 74
small thymus 1 | 16
vertebral fusion 1 | 23

Disease

Carcinoma 196 | 11,493
ovarian cancer 142 | 8,520
osteosarcoma 137 | 7,950
psoriasis 108 | 6,694
lung cancer 94 | 4,740
medulloblastoma, large-cell 89 | 6,241
Cancer 82 | 2,499
glioblastoma 77 | 5,792
Breast cancer 69 | 3,578
malignant mesothelioma 68 | 3,232
atypical teratoid / rhabdoid tumor 66 | 5,112
group 3 medulloblastoma 61 | 4,104
Kidney cancer 52 | 2,613
ependymoma 52 | 4,679
adult high grade glioma 44 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 41 | 3,291
intraductal papillary-mucinous carcinoma (IPMC) 39 | 2,989
primitive neuroectodermal tumor 39 | 3,035
group 4 medulloblastoma 38 | 1,855
invasive ductal carcinoma 38 | 2,951
breast carcinoma 37 | 1,638
oligodendroglioma 37 | 2,850
Intellectual disability 36 | 1,016
diabetes mellitus 36 | 1,728
pancreatic cancer 35 | 2,398
pituitary cancer 34 | 1,972
lung adenocarcinoma 32 | 2,716
non-small cell lung cancer 32 | 2,890
ulcerative colitis 32 | 1,819
Multiple myeloma 31 | 1,332
Pick disease 31 | 1,894
intraductal papillary-mucinous adenoma (IPMA) 31 | 2,955
astrocytic glioma 30 | 2,597
interstitial cystitis 29 | 2,312
Dull intelligence 28 | 645
Low intelligence 28 | 645
Mental Retardation 28 | 645
Mental deficiency 28 | 645
Poor school performance 28 | 645
acute myeloid leukemia 28 | 783
astrocytoma 28 | 1,146
lung carcinoma 28 | 2,843
subependymal giant cell astrocytoma 28 | 2,287
colon cancer 27 | 1,478
Autosomal recessive predisposition 26 | 1,442
tuberculosis 26 | 2,010
Rheumatoid arthritis 25 | 1,191
acute quadriplegic myopathy 25 | 1,158
ductal carcinoma in situ 23 | 1,745
Astrocytoma, Pilocytic 22 | 3,081
Obesity 21 | 678
Short stature 21 | 531
dermatomyositis 21 | 966
pancreatic ductal adenocarcinoma liver metastasis 21 | 1,962
cystic fibrosis 20 | 1,696
primary pancreatic ductal adenocarcinoma 20 | 1,109
juvenile dermatomyositis 19 | 1,187
spina bifida 18 | 1,074
Cockayne syndrome 17 | 60
Waldenstrons macroglobulinemia 17 | 765
adrenocortical carcinoma 17 | 1,428
cutaneous lupus erythematosus 17 | 1,057
pediatric high grade glioma 17 | 1,064
Muscle hypotonia 16 | 571
Cognitive delay 15 | 608
Endometriosis 15 | 540
Global developmental delay 15 | 608
Mental and motor retardation 15 | 608
Schizophrenia 15 | 1,160
Acquired metabolic disease 14 | 336
Broad flat nasal bridge 14 | 236
Nasal bridge wide 14 | 236
Alzheimer's disease 13 | 658
Liver cancer 13 | 604
Photosensitive trichothiodystrophy 13 | 30
Prostatic Neoplasms 13 | 495
nasopharyngeal carcinoma 13 | 1,058
primary Sjogren syndrome 13 | 735
Atopic dermatitis 12 | 952
Bipolar Disorder 12 | 666
Carcinoma, Hepatocellular 12 | 228
Depressive disorder 12 | 409
Epilepsy 12 | 792
Hypoplastic mandible condyle 12 | 275
Liver carcinoma 12 | 240
Mandibular hypoplasia 12 | 275
Micrognathism 12 | 275
Small head 12 | 374
active ulcerative colitis 12 | 764
gastric carcinoma 12 | 807
hepatocellular carcinoma 12 | 547
Breast Neoplasms 11 | 445
Down syndrome 11 | 499
Sensorineural Hearing Loss (disorder) 11 | 284
Short nose 11 | 132
Small nose 11 | 132
urothelial carcinoma 11 | 318
Cataract 10 | 297
Mental Depression 10 | 333
progressive supranuclear palsy 10 | 676

Tissue

Endocrine System 281 | 18,159
Digestive Tract 272 | 17,369
Male tissues 272 | 17,142
Skin and soft tissues 272 | 17,230
Female tissues 269 | 17,400
Liver and Pancreas 269 | 16,750
Urinary Tract 269 | 16,678
Nervous System 267 | 16,725
Blood and immune system 266 | 16,909
Respiratory system 265 | 16,393
Cardiovascular System 252 | 15,192

Target Family

Transcription Factor 137 | 1,400
Non-IDG 91 | 12,091
Enzyme 40 | 4,145
Epigenetic 7 | 242
Kinase 4 | 634
Nuclear Receptor 4 | 48
TF/Epigenetic 3 | 38

GO Process

transcription from RNA polymer... 286 | 286
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein AF-9 MLLT3 Tbio Non-IDG -1.99555 93.8 210
Y-box-binding protein 2 YBX2 Tbio Transcription Factor -1.99119 94.8 236
DNA-directed RNA polymerases I, II, and III subunit RPABC3 POLR2H Tbio Enzyme -1.13403 13.5 180
TFIIA-alpha and beta-like factor GTF2A1L Tbio Non-IDG -0.66901 3.86 222
Sal-like protein 3 SALL3 Tbio Transcription Factor -0.98197 10.1 22
Krueppel-like factor 4 KLF4 Tbio Transcription Factor -2.89447 774.1 686
Transcription regulator protein BACH2 BACH2 Tbio Transcription Factor -1.90906 89.8 184
Methyl-CpG-binding domain protein 1 MBD1 Tbio Transcription Factor -2.23809 171.1 297
ETS-related transcription factor Elf-3 ELF3 Tbio Transcription Factor -2.42034 268.3 328
Krueppel-like factor 13 KLF13 Tbio Transcription Factor -1.40009 27.3 111