Development Level

Tbio 219 | 10,625
Tchem 28 | 1,890
Tdark 21 | 7,003
Tclin 4 | 602

IMPC Term

preweaning lethality, complete... 16 | 633
embryonic lethality prior to t... 8 | 187
preweaning lethality, incomple... 7 | 260
decreased body length 6 | 108
decreased total body fat amoun... 5 | 186
embryonic lethality prior to o... 5 | 148
increased circulating alkaline... 4 | 119
short tibia 4 | 82
abnormal bone structure 3 | 131
abnormal cornea morphology 3 | 24
abnormal embryo size 3 | 112
decreased bone mineral density 3 | 126
decreased grip strength 3 | 123
improved glucose tolerance 3 | 56
increased circulating HDL chol... 3 | 63
increased grip strength 3 | 83
increased lean body mass 3 | 107
thrombocytopenia 3 | 46
abnormal behavior 2 | 226
abnormal forebrain development 2 | 18
abnormal heart morphology 2 | 51
abnormal hindbrain development 2 | 24
abnormal neural tube closure 2 | 37
abnormal retina morphology 2 | 100
abnormal retinal pigmentation 2 | 61
cardiovascular system phenotyp... 2 | 35
decreased B cell number 2 | 30
decreased anxiety-related resp... 2 | 12
decreased body weight 2 | 174
decreased bone mineral content 2 | 157
decreased circulating HDL chol... 2 | 77
decreased circulating glucose ... 2 | 121
decreased circulating sodium l... 2 | 18
decreased circulating total pr... 2 | 41
decreased circulating triglyce... 2 | 83
decreased hemoglobin content 2 | 53
decreased lean body mass 2 | 195
decreased mature B cell number 2 | 25
decreased mean corpuscular hem... 2 | 19
female infertility 2 | 34
increased circulating free fat... 2 | 17
increased circulating potassiu... 2 | 31
increased effector memory CD4-... 2 | 15
increased leukocyte cell numbe... 2 | 37
increased mean corpuscular vol... 2 | 91
male infertility 2 | 62
prenatal lethality prior to he... 2 | 64
abnormal behavioral response t... 1 | 52
abnormal coat appearance 1 | 25
abnormal gait 1 | 51
abnormal head morphology 1 | 10
abnormal heart left ventricle ... 1 | 20
abnormal midbrain development 1 | 22
abnormal placenta size 1 | 10
abnormal retinal inner nuclear... 1 | 5
abnormal skin morphology 1 | 23
abnormal spinal cord morpholog... 1 | 8
abnormal startle reflex 1 | 14
absent heartbeat 1 | 6
decreased CD4-positive, CD25-p... 1 | 24
decreased CD8-positive, naive ... 1 | 5
decreased IgG1 level 1 | 4
decreased KLRG1-positive NK ce... 1 | 9
decreased Ly6C low monocyte nu... 1 | 23
decreased T cell number 1 | 31
decreased caudal vertebrae num... 1 | 49
decreased circulating chloride... 1 | 32
decreased circulating creatini... 1 | 31
decreased effector memory CD8-... 1 | 24
decreased gamma-delta T cell n... 1 | 18
decreased macrophage cell numb... 1 | 4
decreased total retina thickne... 1 | 20
enlarged lymph nodes 1 | 27
impaired pupillary reflex 1 | 14
increased CD4-positive, alpha ... 1 | 15
increased KLRG1+ CD4 alpha bet... 1 | 5
increased Ly6C high monocyte n... 1 | 12
increased Ly6C low monocyte nu... 1 | 8
increased NK cell number 1 | 19
increased blood urea nitrogen ... 1 | 44
increased body weight 1 | 42
increased cardiac muscle contr... 1 | 5
increased circulating choleste... 1 | 53
increased circulating fructosa... 1 | 11
increased circulating glucose ... 1 | 16
increased circulating glycerol... 1 | 11
increased effector memory T-he... 1 | 5
increased eosinophil cell numb... 1 | 9
increased gamma-delta T cell n... 1 | 16
increased mean corpuscular hem... 1 | 25
increased startle reflex 1 | 38
increased total body fat amoun... 1 | 57
pale liver 1 | 5
pale yolk sac 1 | 12
polydactyly 1 | 22
prenatal lethality 1 | 16
shortened ST segment 1 | 9
straub tail 1 | 26
vertebral fusion 1 | 23
vertebral transformation 1 | 12

Disease

ovarian cancer 135 | 8,484
osteosarcoma 129 | 7,933
psoriasis 106 | 6,685
medulloblastoma, large-cell 87 | 6,234
lung cancer 85 | 4,466
Cancer 76 | 2,346
glioblastoma 72 | 5,572
malignant mesothelioma 65 | 3,162
Breast cancer 58 | 3,094
atypical teratoid / rhabdoid tumor 57 | 4,369
Carcinoma 39 | 2,147
pediatric high grade glioma 39 | 2,712
breast carcinoma 38 | 1,614
group 4 medulloblastoma 38 | 1,875
invasive ductal carcinoma 38 | 2,950
intraductal papillary-mucinous carcinoma (IPMC) 37 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 37 | 3,289
primitive neuroectodermal tumor 37 | 3,031
oligodendroglioma 35 | 2,849
group 3 medulloblastoma 34 | 2,254
pancreatic cancer 34 | 2,300
ependymoma 33 | 2,514
diabetes mellitus 32 | 1,663
lung adenocarcinoma 32 | 2,713
pituitary cancer 32 | 1,972
ulcerative colitis 31 | 2,087
Multiple myeloma 30 | 1,327
Pick disease 30 | 1,893
astrocytoma 30 | 1,493
interstitial cystitis 29 | 2,299
intraductal papillary-mucinous adenoma (IPMA) 29 | 2,956
non-small cell lung cancer 29 | 2,798
subependymal giant cell astrocytoma 29 | 2,287
lung carcinoma 27 | 2,844
astrocytic glioma 25 | 2,241
colon cancer 25 | 1,475
acute quadriplegic myopathy 24 | 1,157
pilocytic astrocytoma 24 | 3,086
Rheumatoid Arthritis 23 | 1,160
acute myeloid leukemia 23 | 780
ductal carcinoma in situ 23 | 1,745
sonic hedgehog group medulloblastoma 23 | 1,482
tuberculosis 23 | 1,557
adult high grade glioma 22 | 2,148
primary pancreatic ductal adenocarcinoma 22 | 1,271
cystic fibrosis 20 | 1,665
dermatomyositis 20 | 933
juvenile dermatomyositis 19 | 1,189
medulloblastoma 19 | 1,524
pancreatic ductal adenocarcinoma liver metastasis 19 | 1,795
adrenocortical carcinoma 17 | 1,427
cutaneous lupus erythematosus 16 | 1,056
posterior fossa group A ependymoma 16 | 1,511
spina bifida 16 | 1,064
Intellectual disability 15 | 573
atypical teratoid/rhabdoid tumor 15 | 1,095
Cockayne syndrome 14 | 54
Endometriosis 14 | 535
Waldenstrons macroglobulinemia 14 | 765
posterior fossa group B ependymoma 14 | 1,530
gastric carcinoma 13 | 832
nasopharyngeal carcinoma 13 | 1,056
primary Sjogren syndrome 13 | 789
Acquired metabolic disease 12 | 267
Atopic dermatitis 12 | 944
Obesity 12 | 616
Prostatic Neoplasms 12 | 471
hepatocellular carcinoma 12 | 532
Alzheimer's disease 11 | 644
Photosensitive trichothiodystrophy 11 | 24
active Crohn's disease 11 | 918
urothelial carcinoma 11 | 318
Down syndrome 10 | 548
Liver carcinoma 10 | 217
Peripheral Neuropathy 10 | 303
active ulcerative colitis 10 | 477
tuberculosis and treatment for 6 months 10 | 686
Amyotrophic Lateral Sclerosis 9 | 431
Craniofacial Abnormalities 9 | 147
Mammary Neoplasms 9 | 410
chronic lymphosyte leukemia 9 | 232
inflammatory breast cancer 9 | 404
pancreatic carcinoma 9 | 567
Lung Neoplasms 8 | 171
aldosterone-producing adenoma 8 | 664
esophageal adenocarcinoma 8 | 737
gastric cancer 8 | 430
non primary Sjogren syndrome sicca 8 | 840
progressive supranuclear palsy 8 | 674
Crohn's disease 7 | 304
Leukemia 7 | 88
Leukemia, Myelocytic, Acute 7 | 113
Stomach Neoplasms 7 | 282
chronic rhinosinusitis 7 | 512
fibroadenoma 7 | 557
non-small cell lung carcinoma 7 | 413
sarcoidosis 7 | 358
Asthma 6 | 349
Myocardial Ischemia 6 | 169
Schizophrenia 6 | 501

Tissue

Female tissues 270 | 18,647
Nervous System 270 | 18,561
Digestive Tract 269 | 18,473
Endocrine System 268 | 18,512
Blood and immune system 267 | 17,995
Cardiovascular System 267 | 17,958
Male tissues 266 | 17,969
Skin and soft tissues 266 | 18,115
Urinary Tract 265 | 18,444
Liver and Pancreas 264 | 18,136
Respiratory system 260 | 17,484

Target Family

Transcription Factor 134 | 1,400
Non-IDG 85 | 11,971
Enzyme 35 | 4,146
Epigenetic 7 | 242
Kinase 4 | 634
Nuclear Receptor 4 | 48
TF/Epigenetic 3 | 38

GO Process

transcription from RNA polymer... 272 | 272
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Proto-oncogene c-Fos FOS Tchem Transcription Factor -4.11560 13094.7 961
Zinc finger protein 136 ZNF136 Tdark Transcription Factor 0.12 0.68 102
Forkhead box protein M1 FOXM1 Tbio Transcription Factor -3.09305 1275.4 345
Zinc finger protein 148 ZNF148 Tbio Transcription Factor -1.71996 60.7 178
POU domain, class 3, transcription factor 4 POU3F4 Tbio Transcription Factor -2.24459 179.3 55
Interferon regulatory factor 9 IRF9 Tbio Transcription Factor -1.79340 61.7 168
Zinc finger protein GLIS1 GLIS1 Tbio Transcription Factor -0.87828 10.0 91
Pancreas/duodenum homeobox protein 1 PDX1 Tbio Transcription Factor -2.33707 243.8 508
Host cell factor 1 HCFC1 Tbio Non-IDG -2.50024 341.6 160
Erythroid transcription factor GATA1 Tbio Transcription Factor -2.97791 941.1 675