Development Level

Tbio 70 | 10,625
Tchem 7 | 1,890
Tdark 6 | 7,003

IMPC Term

preweaning lethality, complete... 10 | 633
embryonic lethality prior to o... 5 | 148
embryonic lethality prior to t... 4 | 187
abnormal retina morphology 3 | 100
decreased body length 2 | 108
decreased lean body mass 2 | 195
decreased total body fat amoun... 2 | 186
abnormal bone structure 1 | 131
abnormal epididymis morphology 1 | 31
abnormal heart morphology 1 | 51
abnormal lens morphology 1 | 73
abnormal skin morphology 1 | 23
cataract 1 | 26
decreased CD103-positive CD11b... 1 | 2
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 49
decreased circulating HDL chol... 1 | 77
decreased circulating amylase ... 1 | 24
decreased circulating serum al... 1 | 79
decreased circulating sodium l... 1 | 18
decreased lumbar vertebrae num... 1 | 62
decreased mean corpuscular vol... 1 | 50
enlarged epididymis 1 | 27
enlarged heart 1 | 111
hypoactivity 1 | 89
increased circulating free fat... 1 | 17
increased circulating potassiu... 1 | 31
increased circulating sodium l... 1 | 71
increased exploration in new e... 1 | 56
increased grip strength 1 | 83
increased or absent threshold ... 1 | 128
increased sacral vertebrae num... 1 | 62
preweaning lethality, incomple... 1 | 260
prolonged QRS complex duration 1 | 2
short tibia 1 | 82
vertebral transformation 1 | 12

Disease

ovarian cancer 49 | 8,484
osteosarcoma 35 | 7,933
lung cancer 23 | 4,466
psoriasis 18 | 6,685
Multiple myeloma 15 | 1,327
Breast cancer 13 | 3,094
Cancer 12 | 2,346
diabetes mellitus 12 | 1,663
Cockayne syndrome 11 | 54
glioblastoma 11 | 5,572
medulloblastoma, large-cell 11 | 6,234
Photosensitive trichothiodystrophy 10 | 24
Carcinoma 9 | 2,147
Pick disease 9 | 1,893
acute quadriplegic myopathy 9 | 1,157
atypical teratoid / rhabdoid tumor 9 | 4,369
malignant mesothelioma 9 | 3,162
acute myeloid leukemia 8 | 780
pediatric high grade glioma 8 | 2,712
group 3 medulloblastoma 7 | 2,254
primitive neuroectodermal tumor 7 | 3,031
Xeroderma pigmentosum 6 | 41
astrocytic glioma 6 | 2,241
dermatomyositis 6 | 933
ependymoma 6 | 2,514
lung adenocarcinoma 6 | 2,713
oligodendroglioma 6 | 2,849
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,795
Intellectual disability 5 | 573
Waldenstrons macroglobulinemia 5 | 765
astrocytoma 5 | 1,493
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,289
medulloblastoma 5 | 1,524
pituitary cancer 5 | 1,972
subependymal giant cell astrocytoma 5 | 2,287
Epidermodysplasia verruciformis 4 | 21
Peripheral Neuropathy 4 | 303
Wolf-Hirschhorn syndrome 4 | 32
adult high grade glioma 4 | 2,148
breast carcinoma 4 | 1,614
group 4 medulloblastoma 4 | 1,875
hepatocellular carcinoma 4 | 532
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,988
invasive ductal carcinoma 4 | 2,950
lung carcinoma 4 | 2,844
non-small cell lung cancer 4 | 2,798
pancreatic cancer 4 | 2,300
tuberculosis 4 | 1,557
Neurodegenerative disease 3 | 383
Rheumatoid Arthritis 3 | 1,160
Riley-Day syndrome 3 | 8
Spinocerebellar ataxia type 7 3 | 13
Trichothiodystrophy Syndromes 3 | 5
juvenile dermatomyositis 3 | 1,189
non primary Sjogren syndrome sicca 3 | 840
pancreatic carcinoma 3 | 567
pilocytic astrocytoma 3 | 3,086
primary pancreatic ductal adenocarcinoma 3 | 1,271
Acquired immunodeficiency syndrome 2 | 164
Baller-Gerold syndrome 2 | 14
Cataract 2 | 104
Dystonia 2 | 77
Gaucher disease type 1 2 | 171
Hemangioma 2 | 35
Leukemia 2 | 88
Microcephaly 2 | 149
Mixed connective tissue disease 2 | 16
Neuropathy 2 | 210
Renal Cell Carcinoma 2 | 199
Rift Valley fever 2 | 13
Rothmund-Thomson syndrome 2 | 22
Tinea capitis 2 | 12
Warsaw breakage syndrome 2 | 12
Werner syndrome 2 | 29
active Crohn's disease 2 | 918
aldosterone-producing adenoma 2 | 664
atypical teratoid/rhabdoid tumor 2 | 1,095
cystic fibrosis 2 | 1,665
gastric cancer 2 | 430
inflammatory breast cancer 2 | 404
nasopharyngeal carcinoma 2 | 1,056
posterior fossa group A ependymoma 2 | 1,511
sonic hedgehog group medulloblastoma 2 | 1,482
tuberculosis and treatment for 3 months 2 | 327
Age related macular degeneration 1 | 84
Autosomal dominant cerebellar ataxia 1 | 34
Barrett's esophagus 1 | 183
Benign epilepsy with centrotemporal spikes 1 | 11
COPD 1 | 113
Developmental coordination disorder 1 | 8
Dyslexia 1 | 36
Hypercalcemia 1 | 37
Hypogonadism 1 | 70
Macular degeneration 1 | 41
Motor neuron disease 1 | 39
Progressive multifocal leukoencephalopathy 1 | 24
Specific language impairment 1 | 31
Sunburn 1 | 3
Vaccinia 1 | 37
chorea-acanthocytosis 1 | 11

Tissue

Blood and immune system 83 | 17,995
Urinary Tract 82 | 18,444
Cardiovascular System 81 | 17,958
Digestive Tract 81 | 18,473
Endocrine System 81 | 18,512
Female tissues 81 | 18,647
Liver and Pancreas 81 | 18,136
Nervous System 81 | 18,561
Male tissues 80 | 17,969
Skin and soft tissues 80 | 18,115
Respiratory system 79 | 17,484

Target Family

Non-IDG 48 | 11,971
Enzyme 27 | 4,146
Epigenetic 4 | 242
Kinase 3 | 634
Transcription Factor 1 | 1,400

GO Process

transcription elongation from ... 83 | 83
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
DNA-directed RNA polymerase II subunit RPB7 POLR2G Tbio Enzyme -1.74939 59.4 153
General transcription factor IIH subunit 3 GTF2H3 Tbio Non-IDG -0.79392 6.02 65
General transcription factor IIH subunit 2 GTF2H2 Tbio Non-IDG -0.87357 6.84 120
General transcription factor IIF subunit 2 GTF2F2 Tbio Non-IDG -1.54703 35.9 153
RNA polymerase II transcription factor SIII subunit A3 ELOA3 Tdark Enzyme -0.26996 2.60 46
Cyclin-dependent kinase 7 CDK7 Tchem Kinase -2.28652 191.1 505
Cyclin-H CCNH Tbio Non-IDG -1.98840 89.8 354
CDK-activating kinase assembly factor MAT1 MNAT1 Tbio Enzyme -2.07687 125.7 152
Transcription elongation factor 1 homolog ELOF1 Tdark Non-IDG 0.00000 1.00 54
Transcription initiation factor TFIID subunit 1-like TAF1L Tchem Epigenetic -0.01848 2.40 39