Development Level

Tbio 1,035 | 11,651
Tdark 596 | 6,593
Tchem 90 | 1,388
Tclin 21 | 612

Collection

Kinase: IDG Consortium (Target... 3 | 125
RFA-RM-18-021 3 | 328
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 114 | 979
preweaning lethality, incomple... 47 | 499
embryonic lethality prior to t... 36 | 278
abnormal behavior 27 | 298
embryonic lethality prior to o... 27 | 239
abnormal embryo size 24 | 220
decreased body weight 24 | 161
increased lean body mass 19 | 172
abnormal bone structure 18 | 187
hypoactivity 17 | 132
decreased total body fat amoun... 16 | 207
increased total body fat amoun... 16 | 134
decreased lean body mass 14 | 135
increased startle reflex 14 | 112
decreased circulating glucose ... 13 | 126
hyperactivity 13 | 148
increased bone mineral content 12 | 108
increased mean corpuscular hem... 12 | 96
abnormal heart morphology 11 | 162
decreased circulating serum al... 11 | 82
decreased grip strength 11 | 116
embryonic growth retardation 11 | 106
enlarged heart 11 | 210
abnormal gait 10 | 69
decreased body length 10 | 101
decreased bone mineral content 10 | 151
decreased caudal vertebrae num... 10 | 53
decreased circulating choleste... 10 | 93
decreased leukocyte cell numbe... 10 | 73
decreased prepulse inhibition 10 | 82
decreased vertical activity 10 | 208
increased mean corpuscular vol... 10 | 92
increased or absent threshold ... 10 | 101
male infertility 10 | 123
decreased erythrocyte cell num... 9 | 62
decreased hemoglobin content 9 | 68
hydrometra 9 | 53
increased circulating alkaline... 9 | 122
short tibia 9 | 97
decreased bone mineral density 8 | 126
decreased circulating HDL chol... 8 | 68
decreased circulating triglyce... 8 | 79
impaired glucose tolerance 8 | 75
increased body length 8 | 32
increased bone mineral density 8 | 72
prenatal lethality prior to he... 8 | 87
abnormal seminal vesicle morph... 7 | 114
cataract 7 | 92
decreased circulating insulin ... 7 | 76
decreased lymphocyte cell numb... 7 | 83
edema 7 | 59
improved glucose tolerance 7 | 79
increased circulating HDL chol... 7 | 80
small superior vagus ganglion 7 | 74
thrombocytopenia 7 | 56
abnormal retinal blood vessel ... 6 | 26
decreased circulating LDL chol... 6 | 38
decreased circulating alanine ... 6 | 47
decreased fasted circulating g... 6 | 65
increased mean platelet volume 6 | 45
tremors 6 | 39
abnormal coat-hair pigmentatio... 5 | 64
abnormal kidney morphology 5 | 65
abnormal lens morphology 5 | 81
abnormal tooth morphology 5 | 24
decreased blood urea nitrogen ... 5 | 51
decreased circulating total pr... 5 | 49
decreased heart left ventricle... 5 | 28
increased body weight 5 | 25
increased circulating chloride... 5 | 41
increased circulating choleste... 5 | 66
increased circulating sodium l... 5 | 71
increased erythrocyte cell num... 5 | 39
increased hemoglobin content 5 | 45
small spleen 5 | 19
small testis 5 | 58
vertebral fusion 5 | 23
abnormal behavioral response t... 4 | 66
abnormal bone mineralization 4 | 38
abnormal spleen morphology 4 | 55
abnormal testis morphology 4 | 43
cardiovascular system phenotyp... 4 | 36
decreased anxiety-related resp... 4 | 12
decreased circulating calcium ... 4 | 36
decreased circulating free fat... 4 | 31
decreased circulating fructosa... 4 | 30
decreased mean corpuscular hem... 4 | 50
decreased mean platelet volume 4 | 25
decreased red blood cell distr... 4 | 41
decreased startle reflex 4 | 75
female infertility 4 | 60
increased body temperature 4 | 9
increased circulating creatini... 4 | 38
increased fasted circulating g... 4 | 76
increased mean corpuscular hem... 4 | 36
increased monocyte cell number 4 | 63
increased neutrophil cell numb... 4 | 46
persistence of hyaloid vascula... 4 | 33
syndactyly 4 | 23
vertebral transformation 4 | 12

Disease

Carcinoma 1,172 | 11,493
osteosarcoma 815 | 7,950
ovarian cancer 790 | 8,520
medulloblastoma, large-cell 556 | 6,241
psoriasis 531 | 6,694
glioblastoma 495 | 5,792
group 3 medulloblastoma 463 | 4,104
atypical teratoid / rhabdoid tumor 458 | 5,112
lung cancer 444 | 4,740
ependymoma 369 | 4,679
Breast cancer 329 | 3,578
malignant mesothelioma 309 | 3,232
primitive neuroectodermal tumor 301 | 3,035
Kidney cancer 283 | 2,613
adult high grade glioma 276 | 3,801
oligodendroglioma 260 | 2,850
Cancer 256 | 2,499
intraductal papillary-mucinous neoplasm (IPMN) 253 | 3,291
intraductal papillary-mucinous carcinoma (IPMC) 239 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 225 | 2,955
invasive ductal carcinoma 224 | 2,951
astrocytic glioma 214 | 2,597
Astrocytoma, Pilocytic 199 | 3,081
group 4 medulloblastoma 188 | 1,855
non-small cell lung cancer 180 | 2,890
tuberculosis 173 | 2,010
Pick disease 168 | 1,894
pancreatic cancer 167 | 2,398
lung adenocarcinoma 165 | 2,716
subependymal giant cell astrocytoma 158 | 2,287
lung carcinoma 152 | 2,843
pituitary cancer 145 | 1,972
interstitial cystitis 142 | 2,312
adrenocortical carcinoma 138 | 1,428
breast carcinoma 129 | 1,638
Rheumatoid arthritis 127 | 1,191
astrocytoma 126 | 1,146
pancreatic ductal adenocarcinoma liver metastasis 125 | 1,962
juvenile dermatomyositis 124 | 1,187
Multiple myeloma 121 | 1,332
cystic fibrosis 119 | 1,696
acute quadriplegic myopathy 115 | 1,158
ductal carcinoma in situ 114 | 1,745
spina bifida 114 | 1,074
Intellectual disability 109 | 1,016
acute myeloid leukemia 99 | 783
diabetes mellitus 97 | 1,728
pediatric high grade glioma 94 | 1,064
ulcerative colitis 91 | 1,819
colon cancer 89 | 1,478
dermatomyositis 89 | 966
primary pancreatic ductal adenocarcinoma 84 | 1,109
Schizophrenia 79 | 1,160
Waldenstrons macroglobulinemia 76 | 765
non primary Sjogren syndrome sicca 72 | 891
medulloblastoma 68 | 720
aldosterone-producing adenoma 67 | 665
tuberculosis and treatment for 6 months 65 | 409
Dull intelligence 64 | 645
Low intelligence 64 | 645
Mental Retardation 64 | 645
Mental deficiency 64 | 645
Poor school performance 64 | 645
hepatocellular carcinoma 64 | 547
primary Sjogren syndrome 63 | 735
progressive supranuclear palsy 63 | 676
nasopharyngeal carcinoma 59 | 1,058
Melanoma 57 | 711
cutaneous lupus erythematosus 57 | 1,057
Short stature 56 | 531
Atopic dermatitis 55 | 952
active Crohn's disease 55 | 922
Liver cancer 54 | 604
gastric cancer 53 | 459
sonic hedgehog group medulloblastoma 53 | 467
Breast Neoplasms 52 | 445
Cognitive delay 52 | 608
Global developmental delay 52 | 608
Mental and motor retardation 52 | 608
gastric carcinoma 52 | 807
Mammary Neoplasms 51 | 425
autosomal dominant Emery-Dreifuss muscular dystrophy 51 | 510
Autosomal recessive predisposition 50 | 1,442
Prostatic Neoplasms 49 | 495
active ulcerative colitis 48 | 764
Bipolar Disorder 47 | 666
Epilepsy 46 | 792
Muscle hypotonia 45 | 571
Obesity 45 | 678
Alzheimer's disease 44 | 658
pancreatic carcinoma 44 | 562
Endometriosis 39 | 540
Small head 38 | 374
Acquired metabolic disease 37 | 336
Amyotrophic lateral sclerosis 37 | 451
Multiple Sclerosis 37 | 540
posterior fossa group A ependymoma 37 | 468
Crohn's disease 36 | 321
Seizures 36 | 596
esophageal adenocarcinoma 35 | 737

Tissue

Endocrine System 1,673 | 18,159
Female tissues 1,618 | 17,400
Skin and soft tissues 1,615 | 17,230
Digestive Tract 1,612 | 17,369
Male tissues 1,610 | 17,142
Blood and immune system 1,592 | 16,909
Nervous System 1,590 | 16,725
Urinary Tract 1,574 | 16,678
Liver and Pancreas 1,570 | 16,750
Respiratory system 1,559 | 16,393
Cardiovascular System 1,494 | 15,192

Target Family

Transcription Factor 866 | 1,400
Non-IDG 572 | 12,091
Epigenetic 132 | 242
Enzyme 101 | 4,145
Kinase 32 | 634
TF/Epigenetic 29 | 38
Nuclear Receptor 6 | 48
Transporter 3 | 473
Ion Channel 1 | 344

GO Process

transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Zinc finger protein 215 ZNF215 Tdark Transcription Factor -0.51747 3.15 91
DNA-binding death effector domain-containing protein 2 DEDD2 Tbio Non-IDG -0.55115 3.37 164
Paraspeckle component 1 PSPC1 Tbio Non-IDG -1.75415 48.3 19
DBIRD complex subunit ZNF326 ZNF326 Tbio Non-IDG -0.42207 3.94 120
Zinc finger protein 236 ZNF236 Tbio Transcription Factor -0.40816 2.56 30
Zinc finger CCHC domain-containing protein 9 ZCCHC9 Tdark Non-IDG 0.48 0.71 31
Transcriptional repressor scratch 2 SCRT2 Tdark Transcription Factor 0.22 1.09 25
Zinc finger homeobox protein 2 ZFHX2 Tdark Transcription Factor -0.50515 3.13 28
Transcription factor HES-1 HES1 Tbio Transcription Factor -1.77409 55.5 444
Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific NSD1 Tbio Epigenetic -2.16239 142.5 123