Development Level

Tbio 8 | 11,445
Tchem 4 | 1,598
Tclin 3 | 613

IMPC Phenotype

decreased mean corpuscular vol... 2 | 79
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
decreased body weight 1 | 161
decreased circulating aspartat... 1 | 34
decreased circulating serum al... 1 | 82
decreased grip strength 1 | 116
enlarged heart 1 | 210
increased circulating HDL chol... 1 | 80
increased circulating alanine ... 1 | 13
increased circulating aspartat... 1 | 15
increased circulating choleste... 1 | 66
increased circulating triglyce... 1 | 42
increased lactate dehydrogenas... 1 | 3
increased mean corpuscular hem... 1 | 96
increased startle reflex 1 | 112
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 13 | 11,493
glioblastoma 9 | 5,792
ovarian cancer 9 | 8,520
Cancer 8 | 2,499
Astrocytoma, Pilocytic 7 | 3,081
osteosarcoma 7 | 7,950
tuberculosis 7 | 2,010
lung carcinoma 6 | 2,843
medulloblastoma, large-cell 6 | 6,241
psoriasis 6 | 6,694
adult high grade glioma 5 | 3,801
lung cancer 5 | 4,740
Hypersensitivity reaction type II disease 4 | 253
Influenza 4 | 142
Kidney cancer 4 | 2,613
Rheumatoid arthritis 4 | 1,191
interstitial cystitis 4 | 2,312
malignant mesothelioma 4 | 3,232
subependymal giant cell astrocytoma 4 | 2,287
Allergic hypersensitivity disease 3 | 126
Arthritis 3 | 290
Asthma 3 | 385
Hepatitis B 3 | 108
Human immunodeficiency virus infectious disease 3 | 138
Meningitis 3 | 67
astrocytoma 3 | 1,146
atypical teratoid / rhabdoid tumor 3 | 5,112
ependymoma 3 | 4,679
head and neck cancer and chronic obstructive pulmonary disease 3 | 239
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
invasive ductal carcinoma 3 | 2,951
non-small cell lung cancer 3 | 2,890
pancreatic cancer 3 | 2,398
pediatric high grade glioma 3 | 1,064
Arthritis, Rheumatoid 2 | 174
Centronuclear myopathy 2 | 27
Chemical and Drug Induced Liver Injury 2 | 195
Coronary artery disease 2 | 268
Crohn Disease 2 | 45
Discoid lupus erythematosus 2 | 7
Falciparum malaria 2 | 2
Glomerulonephritis 2 | 46
Hepatitis C 2 | 94
Hypoxia-Ischemia, Brain 2 | 5
Immunologic Deficiency Syndromes 2 | 113
Inflammation 2 | 120
Inflammatory bowel disease 2 | 151
Liver disease 2 | 237
Malaria 2 | 160
Malaria Prevention 2 | 2
Multiple Sclerosis 2 | 540
Ovale malaria 2 | 2
Plasmodium Falciparum Malaria Prevention 2 | 2
Plasmodium Malariae Malaria Prevention 2 | 2
Plasmodium Ovale Malaria Prevention 2 | 2
Pneumonia 2 | 174
Quartan malaria 2 | 2
Systemic lupus erythematosus 2 | 194
Vascular disease 2 | 319
Vivax malaria 2 | 2
active ulcerative colitis 2 | 764
colon cancer 2 | 1,478
cutaneous lupus erythematosus 2 | 1,057
cystic fibrosis 2 | 1,696
diabetes mellitus 2 | 1,728
gastric cancer 2 | 459
group 3 medulloblastoma 2 | 4,104
hepatocellular carcinoma 2 | 547
inflammatory breast cancer 2 | 286
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
medulloblastoma 2 | 720
pancreatic carcinoma 2 | 562
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
primary Sjogren syndrome 2 | 735
primitive neuroectodermal tumor 2 | 3,035
Adenosine deaminase deficiency 1 | 3
Condyloma acuminatum 1 | 7
Dizziness 1 | 26
Encephalitis 1 | 64
Gingival Hemorrhage 1 | 18
IRAK4 Deficiency 1 | 1
Immunodeficiency due to interleukin-1 receptor-associated kinase-4 deficiency 1 | 1
Invasive Pneumococcal Disease, Recurrent Isolated, 1 1 | 2
Keratitis 1 | 62
Leber congenital amaurosis 1 | 69
Lupus Erythematosus, Systemic 1 | 67
Lymphoid leukemia 1 | 160
Lymphoma 1 | 81
Lymphoma, Follicular 1 | 18
Neutrophil abnormality 1 | 20
Neutrophil count decreased 1 | 47
Osteopetrosis 1 | 43
Osteoporosis 1 | 363
Pallor 1 | 40
Recurrent staphylococcal infections 1 | 2
Recurrent streptococcus pneumoniae infections 1 | 3
Renal Cell Carcinoma 1 | 214
Salmonellosis 1 | 42
Thrombophilia 1 | 38
Vertigo 1 | 29

Tissue

Blood and immune system 15 | 16,909
Digestive Tract 15 | 17,369
Endocrine System 15 | 18,159
Female tissues 15 | 17,400
Liver and Pancreas 15 | 16,750
Male tissues 15 | 17,142
Respiratory system 15 | 16,393
Skin and soft tissues 15 | 17,230
Urinary Tract 15 | 16,678
Nervous System 14 | 16,725
Cardiovascular System 13 | 15,192

Target Family

Non-IDG 8 | 12,091
Kinase 5 | 634
Enzyme 1 | 4,145
Nuclear Receptor 1 | 48

GO Process

toll-like receptor 9 signaling... 15 | 15
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Toll-like receptor 7 TLR7 Tclin Non-IDG -3.02761 1078.4 759
Phosphoinositide 3-kinase adapter protein 1 PIK3AP1 Tbio Enzyme -0.26163 1.48 198
Protein unc-93 homolog B1 UNC93B1 Tbio Non-IDG -1.65198 43.3 91
Toll-like receptor 9 TLR9 Tclin Non-IDG -3.07216 1172.9 792
Toll-like receptor 8 TLR8 Tchem Non-IDG -2.36315 232.6 645
TNF receptor-associated factor 6 TRAF6 Tbio Non-IDG -2.74221 511.1 403
Myeloid differentiation primary response protein MyD88 MYD88 Tbio Non-IDG -3.26747 1795.4 672
Bile acid receptor NR1H4 Tclin Nuclear Receptor -2.57379 350.3 293
Interleukin-1 receptor-associated kinase-like 2 IRAK2 Tbio Kinase -1.55042 34.9 550
Interleukin-1 receptor-associated kinase 4 IRAK4 Tchem Kinase -2.28820 202.2 610