Development Level

Tbio 10 | 11,651
Tchem 4 | 1,388
Tclin 2 | 612

IMPC Phenotype

abnormal cecum morphology 1 | 7
decreased circulating serum al... 1 | 82
decreased eosinophil cell numb... 1 | 24
decreased heart weight 1 | 27
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular vol... 1 | 79
enlarged cecum 1 | 5
enlarged uterus 1 | 11
increased circulating HDL chol... 1 | 80
increased circulating alanine ... 1 | 13
increased circulating aspartat... 1 | 15
increased circulating choleste... 1 | 66
increased circulating triglyce... 1 | 42
increased eosinophil cell numb... 1 | 11
increased fasted circulating g... 1 | 76
increased lactate dehydrogenas... 1 | 3
increased neutrophil cell numb... 1 | 46
increased startle reflex 1 | 112
preweaning lethality, incomple... 1 | 499
small superior vagus ganglion 1 | 74

Disease

ovarian cancer 11 | 8,520
Carcinoma 10 | 11,493
glioblastoma 10 | 5,792
lung carcinoma 10 | 2,843
lung cancer 9 | 4,740
medulloblastoma, large-cell 9 | 6,241
malignant mesothelioma 8 | 3,232
tuberculosis 8 | 2,010
interstitial cystitis 7 | 2,312
psoriasis 7 | 6,694
subependymal giant cell astrocytoma 7 | 2,287
diabetes mellitus 6 | 1,728
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
invasive ductal carcinoma 6 | 2,951
osteosarcoma 6 | 7,950
ulcerative colitis 6 | 1,819
Liver Cirrhosis, Experimental 5 | 769
astrocytoma 5 | 1,146
atypical teratoid / rhabdoid tumor 5 | 5,112
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
Asthma 4 | 385
Astrocytoma, Pilocytic 4 | 3,081
Cancer 4 | 2,499
Duchenne muscular dystrophy 4 | 601
Liver disease 4 | 237
Rheumatoid arthritis 4 | 1,191
adrenocortical carcinoma 4 | 1,428
adult high grade glioma 4 | 3,801
cutaneous lupus erythematosus 4 | 1,057
cystic fibrosis 4 | 1,696
dermatomyositis 4 | 966
gastric carcinoma 4 | 807
head and neck cancer and chronic obstructive pulmonary disease 4 | 239
Arthritis 3 | 290
Brain Injuries 3 | 65
Breast cancer 3 | 3,578
Carcinoma, Hepatocellular 3 | 228
Dermatitis 3 | 157
Hypersensitivity reaction type II disease 3 | 253
Inflammatory bowel disease 3 | 151
Liver carcinoma 3 | 240
Lung disease 3 | 142
Obesity 3 | 678
Peritonitis 3 | 43
Pneumonia 3 | 174
Schizophrenia 3 | 1,160
active Crohn's disease 3 | 922
acute myeloid leukemia 3 | 783
group 4 medulloblastoma 3 | 1,855
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
non-small cell lung cancer 3 | 2,890
pancreatic cancer 3 | 2,398
pediatric high grade glioma 3 | 1,064
periodontitis 3 | 293
Acute Promyelocytic Leukemia 2 | 40
Arthritis, Rheumatoid 2 | 174
Atherosclerosis 2 | 291
Behcet Syndrome 2 | 21
Bipolar Disorder 2 | 666
Cerebrovascular disease 2 | 238
Chemical and Drug Induced Liver Injury 2 | 195
Cholestasis 2 | 155
Colorectal Neoplasms 2 | 243
Coronary artery disease 2 | 268
Crohn Disease 2 | 45
Diarrhea 2 | 253
Down syndrome 2 | 499
Fatty liver disease 2 | 103
Kidney disease 2 | 430
Leukemia, Promyelocytic, Acute 2 | 36
Leukocyte adhesion deficiency 2 | 16
Malaria 2 | 160
Mastitis 2 | 48
Multiple Sclerosis 2 | 540
Neoplasm Metastasis 2 | 168
Perinatal necrotizing enterocolitis 2 | 21
Prostatic Neoplasms 2 | 495
Sepsis 2 | 24
active ulcerative colitis 2 | 764
acute quadriplegic myopathy 2 | 1,158
aldosterone-producing adenoma 2 | 665
astrocytic glioma 2 | 2,597
breast carcinoma 2 | 1,638
colon cancer 2 | 1,478
fibroadenoma 2 | 559
gastric cancer 2 | 459
group 3 medulloblastoma 2 | 4,104
hepatocellular carcinoma 2 | 547
inflammatory breast cancer 2 | 286
juvenile dermatomyositis 2 | 1,187
lung adenocarcinoma 2 | 2,716
mucosa-associated lymphoid tissue lymphoma 2 | 484
nephrosclerosis 2 | 333
pituitary cancer 2 | 1,972
posterior fossa group A ependymoma 2 | 468
Gaucher disease type 3 1 | 67
Pancreatitis 1 | 123
Periodontal Diseases 1 | 21
Respiratory Hypersensitivity 1 | 19

Tissue

Blood and immune system 16 | 16,909
Digestive Tract 16 | 17,369
Endocrine System 16 | 18,159
Female tissues 16 | 17,400
Liver and Pancreas 16 | 16,750
Male tissues 16 | 17,142
Skin and soft tissues 16 | 17,230
Urinary Tract 16 | 16,678
Nervous System 15 | 16,725
Respiratory system 15 | 16,393
Cardiovascular System 13 | 15,192

Target Family

Non-IDG 12 | 12,091
Kinase 2 | 634
Enzyme 1 | 4,145
Nuclear Receptor 1 | 48

GO Process

toll-like receptor 4 signaling... 16 | 16
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Bile acid receptor NR1H4 Tclin Nuclear Receptor -2.57379 350.3 293
Receptor-interacting serine/threonine-protein kinase 2 RIPK2 Tchem Kinase -2.03990 107.3 474
Interleukin-1 receptor-associated kinase 1 IRAK1 Tchem Kinase -2.58807 348.8 804
NF-kappa-B inhibitor alpha NFKBIA Tchem Non-IDG -3.34987 1979.8 1300
Toll/interleukin-1 receptor domain-containing adapter protein TIRAP Tbio Non-IDG -1.96027 90.9 401
Monocyte differentiation antigen CD14 CD14 Tbio Non-IDG -1.99511 109.6 2307
Toll-like receptor 4 TLR4 Tchem Non-IDG -3.81927 6905.8 1289
Integrin beta-2 ITGB2 Tclin Non-IDG -2.40405 232.1 1411
Integrin alpha-M ITGAM Tbio Non-IDG -3.63427 3939.5 2165
Phosphoinositide 3-kinase adapter protein 1 PIK3AP1 Tbio Enzyme -0.26163 1.48 198