Development Level

Tbio 8 | 11,445
Tclin 2 | 613
Tchem 1 | 1,598

IMPC Phenotype

abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal forebrain development 1 | 20
abnormal heart morphology 1 | 162
abnormal neural tube closure 1 | 46
abnormal placenta size 1 | 20
abnormal sleep behavior 1 | 70
decreased bone mineral density 1 | 126
decreased exploration in new e... 1 | 11
decreased prepulse inhibition 1 | 82
decreased urine creatinine lev... 1 | 3
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged uterus 1 | 11
hydrometra 1 | 53
increased body length 1 | 32
increased monocyte cell number 1 | 63
pale yolk sac 1 | 25
pallor 1 | 34
prolonged QRS complex duration 1 | 8
small superior vagus ganglion 1 | 74

Disease

Hypothyroidism 9 | 122
Carcinoma 8 | 11,493
psoriasis 6 | 6,694
Congenital hypothyroidism 5 | 26
Goiter 5 | 38
Autosomal recessive predisposition 4 | 1,442
Dull intelligence 4 | 645
Hyperthyroidism 4 | 53
Intellectual disability 4 | 1,016
Low intelligence 4 | 645
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Poor school performance 4 | 645
Thyroid Dyshormonogenesis 1 4 | 6
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
lung adenocarcinoma 4 | 2,716
malignant mesothelioma 4 | 3,232
non-small cell lung cancer 4 | 2,890
osteosarcoma 4 | 7,950
Abdomen distended 3 | 43
Atopic dermatitis 3 | 952
Coarse facial features 3 | 108
Cognitive delay 3 | 608
Constipation 3 | 181
Dyschezia 3 | 135
Endometriosis 3 | 540
Fatigue 3 | 182
Global developmental delay 3 | 608
Hypersomnia 3 | 8
Icterus 3 | 82
Kidney cancer 3 | 2,613
Large bregma sutures 3 | 46
Large fontanelle 3 | 46
Large, late-closing fontanelle 3 | 46
Liver Cirrhosis, Experimental 3 | 769
Macroglossia 3 | 65
Mental and motor retardation 3 | 608
Muscle hypotonia 3 | 571
Pendred Syndrome 3 | 22
Short stature 3 | 531
Thickened facial skin with coarse facial features 3 | 108
Thyrotoxicosis 3 | 38
Umbilical hernia 3 | 93
Wide bregma sutures 3 | 46
group 3 medulloblastoma 3 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
lung cancer 3 | 4,740
Astrocytoma, Pilocytic 2 | 3,081
Atherosclerosis 2 | 291
Autism Spectrum Disorders 2 | 75
Autism spectrum disorder 2 | 101
Autoimmune thyroiditis 2 | 27
Bipolar Disorder 2 | 666
Breast Neoplasms 2 | 445
Carcinoma, Hepatocellular 2 | 228
Chronic granulomatous disease 2 | 13
Graves' disease 2 | 24
Hypertension 2 | 396
Kidney disease 2 | 430
Liver carcinoma 2 | 240
Mammary Neoplasms 2 | 425
Melanoma 2 | 711
Pick disease 2 | 1,894
Thyroid Diseases 2 | 24
Thyroid cancer 2 | 36
Thyroiditis 2 | 29
Thyrotoxic crisis 2 | 2
adrenocortical carcinoma 2 | 1,428
astrocytic glioma 2 | 2,597
atypical teratoid / rhabdoid tumor 2 | 5,112
colon cancer 2 | 1,478
ependymoma 2 | 4,679
glioblastoma 2 | 5,792
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
lung carcinoma 2 | 2,843
medulloblastoma, large-cell 2 | 6,241
nasopharyngeal carcinoma 2 | 1,058
non primary Sjogren syndrome sicca 2 | 891
oligodendroglioma 2 | 2,850
ovarian cancer 2 | 8,520
pancreatic cancer 2 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
primitive neuroectodermal tumor 2 | 3,035
uncontrolled asthma 2 | 56
Abnormality of metabolism/homeostasis 1 | 134
Cerebral palsy 1 | 40
Growth delay 1 | 114
Growth failure 1 | 114
Growth retardation 1 | 115
Influenza 1 | 142
Mesothelioma 1 | 38
Osteoarthritis 1 | 184
Pneumonia 1 | 174
Polyhydramnios 1 | 108
Poor growth 1 | 114
Retrognathia 1 | 54
Very poor growth 1 | 114
facioscapulohumeral dystrophy 1 | 288
head and neck cancer and chronic obstructive pulmonary disease 1 | 239

Tissue

Blood and immune system 11 | 16,909
Digestive Tract 11 | 17,369
Endocrine System 11 | 18,159
Female tissues 11 | 17,400
Liver and Pancreas 11 | 16,750
Male tissues 11 | 17,142
Nervous System 11 | 16,725
Skin and soft tissues 11 | 17,230
Respiratory system 10 | 16,393
Urinary Tract 10 | 16,678
Cardiovascular System 9 | 15,192

Target Family

Enzyme 9 | 4,145
Transcription Factor 1 | 1,400
Transporter 1 | 473

GO Process

thyroid hormone generation 11 | 11
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Carboxypeptidase Q CPQ Tbio Enzyme -2.51783 330.9 81
Type I iodothyronine deiodinase DIO1 Tclin Enzyme -2.19858 153.3 82
Thyroxine 5-deiodinase DIO3 Tbio Enzyme -2.21985 98.0 199
Type II iodothyronine deiodinase DIO2 Tbio Enzyme -2.60036 368.6 134
Thyroid peroxidase TPO Tclin Enzyme -2.83776 580.4 368
Forkhead box protein E1 FOXE1 Tbio Transcription Factor -2.41790 254.9 187
Dual oxidase 1 DUOX1 Tbio Enzyme -2.50131 279.5 85
Dual oxidase 2 DUOX2 Tchem Enzyme -2.45061 251.8 126
Sodium/iodide cotransporter SLC5A5 Tbio Transporter -3.03414 1016.4 360
Iodotyrosine deiodinase 1 IYD Tbio Enzyme -1.49204 31.3 36