Development Level

Tbio 16 | 11,445
Tchem 4 | 1,598
Tclin 4 | 613

IMPC Phenotype

preweaning lethality, complete... 5 | 979
abnormal lens morphology 2 | 81
cataract 2 | 92
decreased lean body mass 2 | 135
embryonic lethality prior to t... 2 | 278
increased total body fat amoun... 2 | 134
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal cornea morphology 1 | 31
abnormal optic disc morphology 1 | 10
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
corneal opacity 1 | 32
decreased body weight 1 | 161
decreased mean corpuscular hem... 1 | 50
decreased total body fat amoun... 1 | 207
fused cornea and lens 1 | 5
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
impaired pupillary reflex 1 | 26
improved glucose tolerance 1 | 79
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased startle reflex 1 | 112
iris synechia 1 | 3
limb grasping 1 | 41
narrow eye opening 1 | 12
persistence of hyaloid vascula... 1 | 33
preweaning lethality, incomple... 1 | 499

Disease

Cancer 16 | 2,499
Carcinoma 16 | 11,493
ovarian cancer 13 | 8,520
Cognitive delay 11 | 608
Global developmental delay 11 | 608
Mental and motor retardation 11 | 608
glioblastoma 11 | 5,792
Muscle hypotonia 10 | 571
Short stature 10 | 531
malignant mesothelioma 10 | 3,232
psoriasis 10 | 6,694
Breast cancer 9 | 3,578
Dull intelligence 8 | 645
Hypothyroidism 8 | 122
Intellectual disability 8 | 1,016
Low intelligence 8 | 645
Mental Retardation 8 | 645
Mental deficiency 8 | 645
Poor school performance 8 | 645
atypical teratoid / rhabdoid tumor 8 | 5,112
interstitial cystitis 8 | 2,312
osteosarcoma 8 | 7,950
Coarse facial features 7 | 108
Congenital hypothyroidism 7 | 26
Constipation 7 | 181
Dyschezia 7 | 135
Orbital separation excessive 7 | 244
Thickened facial skin with coarse facial features 7 | 108
Umbilical hernia 7 | 93
group 3 medulloblastoma 7 | 4,104
Autosomal recessive predisposition 6 | 1,442
Bilateral fifth finger clinodactyly 6 | 110
Cleft Palate 6 | 271
Curvature of little finger 6 | 110
Goiter 6 | 38
Kidney cancer 6 | 2,613
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
medulloblastoma, large-cell 6 | 6,241
Abdomen distended 5 | 43
Acquired scoliosis 5 | 281
Byzanthine arch palate 5 | 194
Craniofacial Abnormalities 5 | 151
Cryptorchidism 5 | 296
Curvature of spine 5 | 282
Delayed bone age 5 | 136
Downward slant of palpebral fissure 5 | 158
Dry skin 5 | 75
Exophthalmos 5 | 112
Fetal Growth Retardation 5 | 189
Icterus 5 | 82
Infant, Small for Gestational Age 5 | 176
Intrauterine retardation 5 | 176
Large bregma sutures 5 | 46
Large fontanelle 5 | 46
Large, late-closing fontanelle 5 | 46
Macroglossia 5 | 65
VACTERL association 5 | 26
Vascular disease 5 | 319
Wide bregma sutures 5 | 46
Xerosis 5 | 75
adult high grade glioma 5 | 3,801
ependymoma 5 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
lung cancer 5 | 4,740
non-small cell lung cancer 5 | 2,890
pancreatic cancer 5 | 2,398
Adenoma 4 | 167
Blepharoptosis 4 | 231
Cardiomyopathy 4 | 116
Congenital Epicanthus 4 | 177
Epilepsy 4 | 792
Feeding difficulties in infancy 4 | 175
Growth delay 4 | 114
Growth failure 4 | 114
Growth retardation 4 | 115
High forehead 4 | 102
Hypoplastic mandible condyle 4 | 275
Kidney disease 4 | 430
Long face 4 | 71
Lung Neoplasms 4 | 232
Mandibular hypoplasia 4 | 275
Poor growth 4 | 114
Premature Birth 4 | 77
Premature birth of newborn 4 | 67
Prominent eyes 4 | 96
Prominent globes 4 | 96
Prostatic Neoplasms 4 | 495
Protruding eyes 4 | 96
Seizures 4 | 596
Short neck 4 | 140
Skin hyperelastic 4 | 32
Strabismus 4 | 270
Tall forehead 4 | 102
Ventricular Septal Defects 4 | 119
Very poor growth 4 | 114
breast carcinoma 4 | 1,638
diabetes mellitus 4 | 1,728
invasive ductal carcinoma 4 | 2,951
lung adenocarcinoma 4 | 2,716
tuberculosis 4 | 2,010

Tissue

Blood and immune system 23 | 16,909
Digestive Tract 23 | 17,369
Endocrine System 23 | 18,159
Female tissues 23 | 17,400
Skin and soft tissues 23 | 17,230
Liver and Pancreas 22 | 16,750
Male tissues 22 | 17,142
Respiratory system 22 | 16,393
Urinary Tract 22 | 16,678
Nervous System 21 | 16,725
Cardiovascular System 19 | 15,192

Target Family

Transcription Factor 13 | 1,400
Kinase 5 | 634
Non-IDG 4 | 12,091
Enzyme 1 | 4,145
Nuclear Receptor 1 | 48

GO Process

thyroid gland development 24 | 24
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Dual specificity mitogen-activated protein kinase kinase 1 MAP2K1 Tclin Kinase -3.07197 862.4 2448
T-box transcription factor TBX1 TBX1 Tbio Transcription Factor -1.99519 95.5 207
Homeobox protein Hox-A3 HOXA3 Tbio Transcription Factor -1.65690 45.4 164
Homeobox protein Hox-B3 HOXB3 Tbio Transcription Factor -1.64244 41.9 120
Thyroglobulin TG Tbio Non-IDG -3.88676 7423.9 1081
Paired box protein Pax-8 PAX8 Tbio Transcription Factor -2.64765 442.1 540
Homeobox protein Hox-A5 HOXA5 Tbio Transcription Factor -2.07535 127.1 369
Homeobox protein Hox-D3 HOXD3 Tbio Transcription Factor -1.51371 40.2 144
Serum response factor SRF Tbio Transcription Factor -2.94583 721.8 474
Hematopoietically-expressed homeobox protein HHEX HHEX Tbio Transcription Factor -3.05655 1150.7 363