Development Level

Tbio 26 | 11,445
Tchem 10 | 1,598
Tclin 6 | 613
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 9 | 979
increased total body fat amoun... 3 | 134
abnormal cornea morphology 2 | 31
abnormal embryo size 2 | 220
abnormal lens morphology 2 | 81
cataract 2 | 92
corneal opacity 2 | 32
decreased lean body mass 2 | 135
embryonic growth retardation 2 | 106
embryonic lethality prior to t... 2 | 278
hemorrhage 2 | 23
impaired pupillary reflex 2 | 26
increased startle reflex 2 | 112
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal eyelid fusion 1 | 3
abnormal facial morphology 1 | 17
abnormal head morphology 1 | 10
abnormal limb morphology 1 | 13
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal optic disc morphology 1 | 10
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal startle reflex 1 | 15
abnormal tail morphology 1 | 25
abnormal testis morphology 1 | 43
absent vibrissae 1 | 12
cyanosis 1 | 7
decreased basophil cell number 1 | 16
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating glucose ... 1 | 126
decreased hemoglobin content 1 | 68
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular hem... 1 | 50
decreased prepulse inhibition 1 | 82
decreased vertical activity 1 | 208
edema 1 | 59
fused cornea and lens 1 | 5
impaired glucose tolerance 1 | 75
increased blood uric acid leve... 1 | 5
increased body length 1 | 32
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased fasted circulating g... 1 | 76
increased vertical activity 1 | 24
iris synechia 1 | 3
limb grasping 1 | 41
mammalian phenotype 1 | 17
narrow eye opening 1 | 12
persistence of hyaloid vascula... 1 | 33
respiratory system phenotype 1 | 2
small superior vagus ganglion 1 | 74
small testis 1 | 58
vertebral fusion 1 | 23

Disease

Carcinoma 30 | 11,493
ovarian cancer 28 | 8,520
Cancer 27 | 2,499
osteosarcoma 25 | 7,950
glioblastoma 22 | 5,792
psoriasis 19 | 6,694
medulloblastoma, large-cell 18 | 6,241
Breast cancer 17 | 3,578
lung cancer 17 | 4,740
malignant mesothelioma 17 | 3,232
atypical teratoid / rhabdoid tumor 16 | 5,112
ependymoma 15 | 4,679
group 3 medulloblastoma 15 | 4,104
pancreatic cancer 15 | 2,398
intraductal papillary-mucinous neoplasm (IPMN) 14 | 3,291
intraductal papillary-mucinous adenoma (IPMA) 12 | 2,955
Kidney cancer 11 | 2,613
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,989
non-small cell lung cancer 11 | 2,890
oligodendroglioma 11 | 2,850
tuberculosis 11 | 2,010
Autosomal recessive predisposition 10 | 1,442
Intellectual disability 10 | 1,016
Schizophrenia 10 | 1,160
Cognitive delay 9 | 608
Dull intelligence 9 | 645
Global developmental delay 9 | 608
Low intelligence 9 | 645
Mental Retardation 9 | 645
Mental and motor retardation 9 | 608
Mental deficiency 9 | 645
Poor school performance 9 | 645
Short stature 9 | 531
adult high grade glioma 9 | 3,801
astrocytic glioma 9 | 2,597
interstitial cystitis 9 | 2,312
invasive ductal carcinoma 9 | 2,951
lung adenocarcinoma 9 | 2,716
primitive neuroectodermal tumor 9 | 3,035
Cleft Palate 8 | 271
Prostatic Neoplasms 8 | 495
Strabismus 8 | 270
breast carcinoma 8 | 1,638
Breast Neoplasms 7 | 445
Epilepsy 7 | 792
Mammary Neoplasms 7 | 425
Multiple myeloma 7 | 1,332
Pick disease 7 | 1,894
Seizures 7 | 596
Sensorineural Hearing Loss (disorder) 7 | 284
Vascular disease 7 | 319
pituitary cancer 7 | 1,972
Alzheimer's disease 6 | 658
Bilateral fifth finger clinodactyly 6 | 110
Bipolar Disorder 6 | 666
Byzanthine arch palate 6 | 194
Curvature of little finger 6 | 110
Fetal Growth Retardation 6 | 189
Hypoplastic mandible condyle 6 | 275
Immune system cancer 6 | 140
Lung Neoplasms 6 | 232
Mandibular hypoplasia 6 | 275
Micrognathism 6 | 275
Nerve Degeneration 6 | 121
Orbital separation excessive 6 | 244
Small head 6 | 374
Splenomegaly 6 | 190
ductal carcinoma in situ 6 | 1,745
group 4 medulloblastoma 6 | 1,855
primary pancreatic ductal adenocarcinoma 6 | 1,109
Acquired scoliosis 5 | 281
Amyotrophic lateral sclerosis 5 | 451
Chemical and Drug Induced Liver Injury 5 | 195
Cleft Lip 5 | 141
Craniofacial Abnormalities 5 | 151
Curvature of spine 5 | 282
Downward slant of palpebral fissure 5 | 158
Infant, Small for Gestational Age 5 | 176
Intrauterine retardation 5 | 176
Lymphoid leukemia 5 | 160
Melanoma 5 | 711
Muscle hypotonia 5 | 571
Obesity 5 | 678
Premature Birth 5 | 77
Premature birth of newborn 5 | 67
Skin cancer 5 | 469
astrocytoma 5 | 1,146
cystic fibrosis 5 | 1,696
diabetes mellitus 5 | 1,728
lung carcinoma 5 | 2,843
progressive supranuclear palsy 5 | 676
spina bifida 5 | 1,074
subependymal giant cell astrocytoma 5 | 2,287
ulcerative colitis 5 | 1,819
Depressive disorder 4 | 409
Down syndrome 4 | 499
acute quadriplegic myopathy 4 | 1,158
adrenocortical carcinoma 4 | 1,428
nasopharyngeal carcinoma 4 | 1,058
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962

Tissue

Endocrine System 42 | 18,159
Skin and soft tissues 42 | 17,230
Digestive Tract 41 | 17,369
Female tissues 41 | 17,400
Blood and immune system 40 | 16,909
Liver and Pancreas 40 | 16,750
Male tissues 40 | 17,142
Nervous System 40 | 16,725
Respiratory system 39 | 16,393
Urinary Tract 39 | 16,678
Cardiovascular System 36 | 15,192

Target Family

Transcription Factor 14 | 1,400
Non-IDG 12 | 12,091
Kinase 11 | 634
Enzyme 3 | 4,145
Epigenetic 1 | 242
TF/Epigenetic 1 | 38
Transporter 1 | 473

GO Process

thymus development 43 | 43
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transcription factor MafB MAFB Tbio Transcription Factor -2.01655 101.2 191
Mitotic spindle assembly checkpoint protein MAD1 MAD1L1 Tbio Non-IDG -1.17500 13.6 283
Zinc finger and BTB domain-containing protein 1 ZBTB1 Tbio Transcription Factor -0.66768 5.75 59
Dual specificity mitogen-activated protein kinase kinase 1 MAP2K1 Tclin Kinase -3.07197 862.4 2448
Ephrin type-B receptor 3 EPHB3 Tchem Kinase -1.68968 47.7 409
Homeobox protein SIX4 SIX4 Tbio Transcription Factor -2.31722 197.8 141
T-box transcription factor TBX1 TBX1 Tbio Transcription Factor -1.99519 95.5 207
Homeobox protein Hox-A3 HOXA3 Tbio Transcription Factor -1.65690 45.4 164
Paired box protein Pax-1 PAX1 Tbio Transcription Factor -2.03339 106.1 245
CST complex subunit CTC1 CTC1 Tbio Non-IDG -1.74818 54.2 49