Development Level

Tbio 5 | 11,445

Disease

Leigh disease 4 | 100
Beriberi 3 | 12
Carcinoma 3 | 11,493
biotin-responsive basal ganglia disease 3 | 8
lung cancer 3 | 4,740
non-small cell lung cancer 3 | 2,890
Autosomal recessive predisposition 2 | 1,442
Wernicke-Korsakoff syndrome 2 | 10
active Crohn's disease 2 | 922
active ulcerative colitis 2 | 764
adrenocortical carcinoma 2 | 1,428
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
invasive ductal carcinoma 2 | 2,951
lung adenocarcinoma 2 | 2,716
ovarian cancer 2 | 8,520
tuberculosis 2 | 2,010
Abnormal urinary amino-acid findings 1 | 38
Abnormal vision 1 | 52
Acidosis, Lactic 1 | 97
Aminoaciduria 1 | 38
Amish lethal microcephaly 1 | 1
Amyotrophic lateral sclerosis type 1 1 | 23
Amyotrophic lateral sclerosis type 4 1 | 5
Anemia 1 | 365
Anemia, Megaloblastic 1 | 16
Anorexia 1 | 43
Atrial Septal Defects 1 | 85
Basal Ganglia Diseases 1 | 14
Basal ganglia disease, biotin-responsive 1 | 1
Biotin deficiency 1 | 10
Brain disease 1 | 96
Cardiac Arrhythmia 1 | 103
Cardiac conduction abnormalities 1 | 78
Conduction disorder of the heart 1 | 79
Cone dystrophy 1 | 71
Cone/cone-rod dystrophy 1 | 20
Decreased platelet count 1 | 111
Dermatologic disorders 1 | 93
Detrusor sphincter dyssynergia 1 | 8
Diarrhea 1 | 253
Dizziness 1 | 26
Duchenne muscular dystrophy 1 | 601
Dystonia 1 | 164
Dystonic disease 1 | 106
EKG abnormalities 1 | 78
Electrocardiogram abnormal 1 | 81
Electrocardiogram change 1 | 78
Headache 1 | 37
Highly variable clinical phenotype 1 | 150
Highly variable phenotype and severity 1 | 150
Highly variable phenotype, even within families 1 | 150
Hoarseness 1 | 31
Lactic acidemia 1 | 95
Lethargy 1 | 77
Liver Cirrhosis, Experimental 1 | 769
MICROCEPHALY, AMISH TYPE (disorder) 1 | 1
Megaloblastic anemia 1 | 18
Microcephaly 1 | 166
Microcephaly, Amish Type 1 | 1
Muscle Spasticity 1 | 195
Neuropathy 1 | 261
Pallor 1 | 40
Paresthesia 1 | 32
Phenotypic variability 1 | 150
Pyruvate decarboxylase deficiency 1 | 16
Retinal Degeneration 1 | 106
Scleritis 1 | 6
Sensorineural Hearing Loss (disorder) 1 | 284
Sensorineural hearing loss 1 | 106
Sideroblastic anemia 1 | 20
Skin Abnormalities 1 | 37
Striatal necrosis, bilateral, and progressive polyneuropathy 1 | 1
THIAMINE METABOLISM DYSFUNCTION SYNDROME 4 (BILATERAL STRIATAL DEGENERATION AND PROGRESSIVE POLYNEUROPATHY TYPE) 1 | 1
Thiamine Metabolism Dysfunction Syndrome 2 (Biotin- or Thiamine-Responsive Type) 1 | 1
Thrombocytopenia 1 | 197
Type 2 diabetes mellitus 1 | 272
Ventricular Septal Defects 1 | 119
Vertigo 1 | 29
Wernicke encephalopathy 1 | 12
Wolfram syndrome 1 | 12
astrocytic glioma 1 | 2,597
basal ganglia disease 1 | 1
breast carcinoma 1 | 1,638
chronic rhinosinusitis 1 | 512
colon cancer 1 | 1,478
cystic fibrosis and chronic rhinosinusitis 1 | 214
dermatomyositis 1 | 966
diabetes mellitus 1 | 1,728
fibroadenoma 1 | 559
inflammatory breast cancer 1 | 286
interstitial lung disease 1 | 298
intraductal papillary-mucinous carcinoma (IPMC) 1 | 2,989
limb girdle muscular dystrophy 2A 1 | 213
oligodendroglioma 1 | 2,850
pituitary cancer 1 | 1,972
pterygium 1 | 76
spina bifida 1 | 1,074
subependymal giant cell astrocytoma 1 | 2,287
substance-related disorder 1 | 162
urothelial carcinoma 1 | 318

Tissue

Blood and immune system 5 | 16,909
Cardiovascular System 5 | 15,192
Digestive Tract 5 | 17,369
Endocrine System 5 | 18,159
Female tissues 5 | 17,400
Liver and Pancreas 5 | 16,750
Male tissues 5 | 17,142
Nervous System 5 | 16,725
Respiratory system 5 | 16,393
Skin and soft tissues 5 | 17,230
Urinary Tract 5 | 16,678

Target Family

Transporter 3 | 473
Enzyme 1 | 4,145
Kinase 1 | 634

GO Process

thiamine-containing compound m... 5 | 5
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Mitochondrial thiamine pyrophosphate carrier SLC25A19 Tbio Transporter -2.34612 194.5 69
Thiamine transporter 2 SLC19A3 Tbio Transporter -1.83955 73.2 85
Thiamin pyrophosphokinase 1 TPK1 Tbio Kinase -1.54318 34.4 114
Thiamine-triphosphatase THTPA Tbio Enzyme -1.53297 36.7 119
Thiamine transporter 1 SLC19A2 Tbio Transporter -2.02810 109.1 49