Development Level

Tbio 10 | 11,445
Tclin 3 | 613
Tchem 1 | 1,598

IMPC Phenotype

preweaning lethality, complete... 3 | 979
embryonic lethality prior to t... 2 | 278
abnormal behavior 1 | 298
abnormal embryo development 1 | 7
abnormal embryo turning 1 | 31
abnormal locomotor behavior 1 | 24
abnormal pericardium morpholog... 1 | 26
abnormal spleen morphology 1 | 55
abnormal vocalization 1 | 21
decreased body weight 1 | 161
decreased lean body mass 1 | 135
decreased total body fat amoun... 1 | 207
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
increased aggression 1 | 4
increased heart rate variabili... 1 | 7
increased lean body mass 1 | 172
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
limb grasping 1 | 41

Disease

Carcinoma 8 | 11,493
medulloblastoma, large-cell 8 | 6,241
glioblastoma 7 | 5,792
lung cancer 7 | 4,740
ependymoma 6 | 4,679
osteosarcoma 6 | 7,950
ovarian cancer 6 | 8,520
Cancer 5 | 2,499
Intellectual disability 5 | 1,016
Pick disease 5 | 1,894
atypical teratoid / rhabdoid tumor 5 | 5,112
psoriasis 5 | 6,694
Breast cancer 4 | 3,578
Dull intelligence 4 | 645
Low intelligence 4 | 645
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Poor school performance 4 | 645
astrocytic glioma 4 | 2,597
group 3 medulloblastoma 4 | 4,104
oligodendroglioma 4 | 2,850
Alcoholic Intoxication, Chronic 3 | 289
Astrocytoma, Pilocytic 3 | 3,081
Autistic Disorder 3 | 364
Bipolar Disorder 3 | 666
Cerebellar Ataxia 3 | 304
Cognitive delay 3 | 608
Global developmental delay 3 | 608
Kidney cancer 3 | 2,613
Mental and motor retardation 3 | 608
Parkinson's disease 3 | 392
Schizophrenia 3 | 1,160
adult high grade glioma 3 | 3,801
breast carcinoma 3 | 1,638
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
lung adenocarcinoma 3 | 2,716
lung carcinoma 3 | 2,843
non-small cell lung cancer 3 | 2,890
Abnormally small eyeball 2 | 97
Acquired metabolic disease 2 | 336
Alzheimer's disease 2 | 658
Ameloblastoma 2 | 24
Autism Spectrum Disorders 2 | 75
Autism spectrum disorder 2 | 101
Autosomal recessive predisposition 2 | 1,442
Basal cell carcinoma of skin 2 | 2
Cognitive disorder 2 | 50
Congenital ocular coloboma (disorder) 2 | 40
Decreased size of eyeball 2 | 97
Depressive disorder 2 | 409
Endometrial cancer 2 | 311
Endometriosis 2 | 540
Epilepsy 2 | 792
Gilles de la Tourette syndrome 2 | 47
Increased serum lactate 2 | 60
Liver Cirrhosis, Experimental 2 | 769
Liver cancer 2 | 604
Major Depressive Disorder 2 | 301
Mental Depression 2 | 333
Microphthalmos 2 | 100
Multiple Sclerosis 2 | 540
Muscle hypotonia 2 | 571
Nevoid basal cell carcinoma syndrome 2 | 16
Osteoporosis 2 | 363
Polydactyly of toes 2 | 12
Polydactyly preaxial type 1 2 | 9
Seizures 2 | 596
Short stature 2 | 531
Skin cancer 2 | 469
Syndactyly of fingers 2 | 48
Syndactyly of the toes 2 | 45
Unipolar Depression 2 | 250
adrenocortical carcinoma 2 | 1,428
colon cancer 2 | 1,478
cutaneous lupus erythematosus 2 | 1,057
cystic fibrosis 2 | 1,696
ductal carcinoma in situ 2 | 1,745
esophageal adenocarcinoma 2 | 737
group 4 medulloblastoma 2 | 1,855
interstitial cystitis 2 | 2,312
invasive ductal carcinoma 2 | 2,951
malignant mesothelioma 2 | 3,232
nasopharyngeal carcinoma 2 | 1,058
non primary Sjogren syndrome sicca 2 | 891
pancreatic cancer 2 | 2,398
pediatric high grade glioma 2 | 1,064
pituitary cancer 2 | 1,972
progressive supranuclear palsy 2 | 676
subependymal giant cell astrocytoma 2 | 2,287
tuberculosis 2 | 2,010
Dysthymic Disorder 1 | 17
Hyperostosis 1 | 18
Narrow nose 1 | 20
Personality disorder 1 | 25
Pinched bridge of nose 1 | 14
Pinched nasal bridge 1 | 14
Porencephaly 1 | 20
Seasonal affective disorder 1 | 28

Tissue

Digestive Tract 13 | 17,369
Endocrine System 13 | 18,159
Female tissues 13 | 17,400
Nervous System 13 | 16,725
Urinary Tract 12 | 16,678
Blood and immune system 11 | 16,909
Male tissues 11 | 17,142
Liver and Pancreas 10 | 16,750
Respiratory system 10 | 16,393
Skin and soft tissues 10 | 17,230
Cardiovascular System 9 | 15,192

Target Family

Non-IDG 6 | 12,091
Transcription Factor 4 | 1,400
Enzyme 2 | 4,145
GPCR 1 | 408
Transporter 1 | 473

GO Process

thalamus development 14 | 14
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Forkhead box protein B1 FOXB1 Tbio Transcription Factor -1.17019 15.7 110
Smoothened homolog SMO Tclin GPCR -1.17466 14.5 415
Oligodendrocyte transcription factor 2 OLIG2 Tbio Transcription Factor -2.64017 420.5 368
Contactin-associated protein-like 2 CNTNAP2 Tbio Non-IDG -2.36156 228.4 191
Patched domain-containing protein 1 PTCHD1 Tbio Non-IDG -0.84569 7.72 81
2-oxoglutarate dehydrogenase, mitochondrial OGDH Tbio Enzyme -2.47825 290.5 147
Pleiotrophin PTN Tbio Non-IDG -2.85163 746.7 392
Homeobox protein GBX-2 GBX2 Tbio Transcription Factor -1.75250 59.9 240
Low-density lipoprotein receptor-related protein 6 LRP6 Tbio Non-IDG -2.44778 273.2 424
Sodium-dependent serotonin transporter SLC6A4 Tclin Transporter -3.63283 4453.8 245