Development Level

Tbio 64 | 11,445
Tdark 5 | 6,588

IMPC Phenotype

preweaning lethality, complete... 9 | 979
preweaning lethality, incomple... 3 | 499
abnormal embryo size 2 | 220
decreased leukocyte cell numbe... 2 | 73
embryonic growth retardation 2 | 106
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
abnormal behavior 1 | 298
abnormal coat-hair pigmentatio... 1 | 64
abnormal lens morphology 1 | 81
abnormal pericardium morpholog... 1 | 26
cataract 1 | 92
decreased bone mineral density 1 | 126
decreased circulating aspartat... 1 | 34
decreased fasted circulating g... 1 | 65
decreased lymphocyte cell numb... 1 | 83
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
edema 1 | 59
hypoactivity 1 | 132
increased bone mineral density 1 | 72
increased circulating creatini... 1 | 38
increased fasted circulating g... 1 | 76
increased mean corpuscular hem... 1 | 96
increased neutrophil cell numb... 1 | 46
male infertility 1 | 123
prenatal lethality prior to he... 1 | 87
small testis 1 | 58

Disease

Carcinoma 44 | 11,493
ovarian cancer 44 | 8,520
osteosarcoma 30 | 7,950
group 3 medulloblastoma 28 | 4,104
lung cancer 28 | 4,740
medulloblastoma, large-cell 26 | 6,241
glioblastoma 21 | 5,792
psoriasis 21 | 6,694
malignant mesothelioma 16 | 3,232
ependymoma 15 | 4,679
Multiple myeloma 14 | 1,332
Breast cancer 13 | 3,578
atypical teratoid / rhabdoid tumor 13 | 5,112
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
Kidney cancer 11 | 2,613
Waldenstrons macroglobulinemia 11 | 765
acute quadriplegic myopathy 11 | 1,158
non-small cell lung cancer 11 | 2,890
primitive neuroectodermal tumor 11 | 3,035
astrocytic glioma 10 | 2,597
oligodendroglioma 10 | 2,850
tuberculosis and treatment for 6 months 9 | 409
dermatomyositis 8 | 966
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
Pick disease 7 | 1,894
adult high grade glioma 7 | 3,801
astrocytoma 7 | 1,146
group 4 medulloblastoma 7 | 1,855
invasive ductal carcinoma 7 | 2,951
lung adenocarcinoma 7 | 2,716
Gaucher disease type 1 6 | 180
HIV Infections 6 | 102
juvenile dermatomyositis 6 | 1,187
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
subependymal giant cell astrocytoma 6 | 2,287
Autosomal recessive predisposition 5 | 1,442
Intellectual disability 5 | 1,016
diabetes mellitus 5 | 1,728
hepatocellular carcinoma 5 | 547
nasopharyngeal carcinoma 5 | 1,058
pediatric high grade glioma 5 | 1,064
progressive supranuclear palsy 5 | 676
adrenocortical carcinoma 4 | 1,428
aldosterone-producing adenoma 4 | 665
atypical teratoid/rhabdoid tumor 4 | 357
breast carcinoma 4 | 1,638
colon cancer 4 | 1,478
pituitary cancer 4 | 1,972
Amyotrophic lateral sclerosis 3 | 451
Bilateral fifth finger clinodactyly 3 | 110
Byzanthine arch palate 3 | 194
Cancer 3 | 2,499
Curvature of little finger 3 | 110
Disease Progression 3 | 136
Epilepsy 3 | 792
Microcephaly 3 | 166
Polycystic ovary syndrome 3 | 360
Rheumatoid arthritis 3 | 1,191
Spinocerebellar ataxia type 31 3 | 8
Stomach Neoplasms 3 | 300
acute myeloid leukemia 3 | 783
non primary Sjogren syndrome sicca 3 | 891
pancreatic cancer 3 | 2,398
posterior fossa group B ependymoma 3 | 416
spina bifida 3 | 1,074
Adenocarcinoma of lung 2 | 142
Alzheimer's disease 2 | 658
Astrocytoma, Pilocytic 2 | 3,081
Bipolar Disorder 2 | 666
Cognitive delay 2 | 608
Creatine phosphokinase serum increased 2 | 110
Disease Models, Animal 2 | 155
Distal limb muscle weakness due to peripheral neuropathy 2 | 62
Distal muscle weakness 2 | 62
Dull intelligence 2 | 645
Elevated creatine kinase 2 | 110
Global developmental delay 2 | 608
Hematologic cancer 2 | 12
Hyperreflexia 2 | 209
Hypoplastic mandible condyle 2 | 275
Immune system cancer 2 | 140
Liver cancer 2 | 604
Male infertility 2 | 206
Mastocytosis 2 | 27
Mental and motor retardation 2 | 608
Mental deficiency 2 | 645
Neurodegenerative disease 2 | 414
Poor school performance 2 | 645
Progressive disorder 2 | 142
Schizophrenia 2 | 1,160
Uranostaphyloschisis 2 | 167
Ventricular Septal Defects 2 | 119
gastric cancer 2 | 459
interstitial cystitis 2 | 2,312
medulloblastoma 2 | 720
pancreatic carcinoma 2 | 562
primary Sjogren syndrome 2 | 735
primary pancreatic ductal adenocarcinoma 2 | 1,109
tuberculosis and treatment for 3 months 2 | 179

Tissue

Blood and immune system 69 | 16,909
Cardiovascular System 69 | 15,192
Digestive Tract 69 | 17,369
Endocrine System 69 | 18,159
Female tissues 69 | 17,400
Liver and Pancreas 69 | 16,750
Male tissues 69 | 17,142
Nervous System 69 | 16,725
Respiratory system 69 | 16,393
Skin and soft tissues 69 | 17,230
Urinary Tract 69 | 16,678

Target Family

Non-IDG 58 | 12,091
Enzyme 9 | 4,145
Transcription Factor 2 | 1,400

GO Process

termination of RNA polymerase ... 69 | 69
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
RNA-binding protein 8A RBM8A Tbio Non-IDG -3.16448 1415.1 94
THO complex subunit 7 homolog THOC7 Tbio Non-IDG -0.34772 2.04 61
THO complex subunit 5 homolog THOC5 Tbio Non-IDG -1.14189 16.8 116
Cleavage and polyadenylation specificity factor subunit 3 CPSF3 Tbio Non-IDG -1.47182 27.3 190
THO complex subunit 6 homolog THOC6 Tbio Non-IDG -1.77416 57.9 131
Splicing factor U2AF 26 kDa subunit U2AF1L4 Tbio Non-IDG -0.17609 1.86 61
Polyadenylate-binding protein 2 PABPN1 Tbio Non-IDG -2.48757 316.4 120
Zinc finger protein 473 ZNF473 Tbio Transcription Factor -1.11630 12.6 101
Cleavage and polyadenylation specificity factor subunit 1 CPSF1 Tbio Non-IDG -1.00806 8.79 51
Transcription termination factor 2 TTF2 Tbio Non-IDG -0.36173 2.95 140