Development Level

Tbio 2 | 11,445

IMPC Phenotype

embryonic lethality prior to t... 1 | 278
preweaning lethality, complete... 1 | 979

Disease

Breast cancer 2 | 3,578
Cancer 2 | 2,499
ALL 1 | 9
Abnormal hair quantity 1 | 16
Anemia, Aplastic 1 | 7
Aplastic Anemia 1 | 21
Ataxia telangiectasia 1 | 34
Autoimmune hemolytic anemia 1 | 31
Basal cell carcinoma 1 | 54
Birthmark 1 | 35
Bone marrow hypocellularity 1 | 20
Breast Neoplasms 1 | 445
Bronchiectasis 1 | 64
Cachexia 1 | 50
Cafe-au-Lait Spots 1 | 37
Carcinoma, Basal Cell 1 | 28
Choanal Atresia 1 | 42
Chromosome Breakage 1 | 36
Chronic diarrhea 1 | 29
Concave bridge of nose 1 | 195
Convex nasal bridge 1 | 57
Convex nasal ridge 1 | 37
Decreased platelet count 1 | 111
Deep philtrum 1 | 21
Depressed nasal bridge 1 | 195
Depressed nasal root/bridge 1 | 195
Depressed philtrum 1 | 21
Diarrhea 1 | 253
Dysgammaglobulinemia 1 | 10
Esophageal Neoplasms 1 | 69
Familial cancer of breast 1 | 12
Gastrointestinal infection 1 | 4
Genetic Predisposition to Disease 1 | 27
Glioma 1 | 74
Head and Neck Neoplasms 1 | 26
Hearing abnormality 1 | 12
Hereditary Breast and Ovarian Cancer Syndrome 1 | 14
Hydronephrosis 1 | 89
Hyperactive behavior 1 | 91
Hyperplasia of malar bones 1 | 4
Hyperplasia of nose 1 | 23
Hypertrophic cardiomyopathy 15 1 | 1
Hypertrophy of nose 1 | 23
Increased chromosomal breakage 1 | 27
Increased frequency of micturition 1 | 2
Infectious disease of lung 1 | 29
Large auricle 1 | 87
Large dysplastic ears 1 | 87
Large nose 1 | 23
Large pinnae 1 | 87
Large prominent ears 1 | 87
Large protruding ears 1 | 87
Large, floppy ears 1 | 87
Lead Poisoning 1 | 6
Long nose 1 | 15
Low B cell count 1 | 8
Low anterior hairline 1 | 30
Lymphoma 1 | 81
MELANOMA, CUTANEOUS MALIGNANT, SUSCEPTIBILITY TO, 6 1 | 1
Macrotia 1 | 87
Malignant neoplasm of breast 1 | 15
Mammary Neoplasms 1 | 425
Mammary Neoplasms, Experimental 1 | 154
Mastoiditis 1 | 8
Melanoma 1 | 711
Mental deterioration 1 | 32
Mesothelioma 1 | 38
Microcephaly 1 | 166
Multiple pulmonary infections 1 | 29
Neoplasm Invasiveness 1 | 161
Neoplasm Recurrence, Local 1 | 37
Nerve Degeneration 1 | 121
Neuro-degenerative disease 1 | 43
Neurodegenerative Disorders 1 | 79
Nijmegen breakage syndrome 1 | 24
Otitis Media 1 | 52
Ovarian Failure, Premature 1 | 9
Paranasal Sinus Diseases 1 | 34
Prominent midface 1 | 4
Prominent nasal bridge 1 | 57
Prostate cancer, familial 1 | 13
Recurrent bronchitis 1 | 23
Recurrent gastrointestinal infections 1 | 4
Recurrent pneumonia 1 | 29
Recurrent pulmonary infections 1 | 29
Recurrent sinopulmonary infections 1 | 6
Recurrent urinary tract infection 1 | 24
Retrognathia 1 | 54
Rhabdomyosarcoma 1 | 39
Sinusitis 1 | 65
Skin Neoplasms 1 | 69
Stomach Neoplasms 1 | 300
Stomatitis 1 | 21
Stricture of anus 1 | 13
T-Lymphocytopenia 1 | 9
Thrombocytopenia 1 | 197
Xeroderma pigmentosum group D 1 | 33
Xeroderma pigmentosum group F 1 | 22
Xeroderma pigmentosum group G 1 | 16
medulloblastoma 1 | 720

Tissue

Blood and immune system 2 | 16,909
Cardiovascular System 2 | 15,192
Digestive Tract 2 | 17,369
Endocrine System 2 | 18,159
Female tissues 2 | 17,400
Liver and Pancreas 2 | 16,750
Male tissues 2 | 17,142
Nervous System 2 | 16,725
Respiratory system 2 | 16,393
Skin and soft tissues 2 | 17,230
Urinary Tract 2 | 16,678

Target Family

Non-IDG 2 | 12,091

GO Process

telomere maintenance via telom... 2 | 2
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
DNA repair protein XRCC3 XRCC3 Tbio Non-IDG -2.50791 314.0 414
Nibrin NBN Tbio Non-IDG -1.95649 97.2 1094